Registered Attendees
Registered Attendees
Print This PageRegistered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:
- Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting
(You can edit your own abstract from My Account page as well)
NOTE: Abstract authors/submitters may choose to not have their abstract available online before the meeting...these abstracts will be available in the Abstract Book at the meeting.
- Full participant list, including joint meeting participants
- Printable Invoices and Invitation Letters
- Scholarship Information
- Lodging Information
Login to My Account page
Close Window
Big Sky Resort Floorplan
This meeting took place in 2013
For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.
Meeting Details
Multiple Sclerosis (A1)
Organizer(s) Trevor J. Kilpatrick, Brenda Banwell and Hartmut Wekerle
January 11 - January 16, 2013
Big Sky Resort • Big Sky, Montana USA
Abstract Deadline: September 12, 2012
Late Abstract Deadline: October 11, 2012
Scholarship Deadline: September 12, 2012
Early Registration Deadline: November 12, 2012
Sponsored by Biogen Idec and the National Multiple Sclerosis Society
CME Information
Summary of Meeting:
Multiple sclerosis (MS) is a complex disease in which genetic, environmental and stochastic factors all play a part to induce aberrant interactions between the immune system and neural cells, ultimately transforming into progressive neurological disability. Our understanding of MS is rapidly evolving, and multiple areas of research are showing great promise of future treatment or cure. However, further progress will depend on establishing a deep understanding of the underlying disease mechanisms. With this in mind, this meeting aims to: 1) Define integrated approaches by which to study disease pathogenesis, which represents a critical barrier to progress in the field; 2) Provide an up-to-date perspective on molecular pathogenesis and how this might be used to optimize patient management; 3) Define state-of-the-art technologies by which to quantitate disease burden; 4) Discuss key elements concerning the concept of disease heterogeneity and how emergent approaches to disease stratification can optimize management strategies; and 5) Provide perspectives concerning the potential therapeutic applications of neuroprotective, regenerative and bioengineering-based strategies, and how these might complement immunotherapy. Speakers have been carefully selected on the basis that, independent of whether they are basic scientists or clinician researchers, they each have a track record in adopting a multi-disciplinary approach that has enabled the application of discoveries in one area of endeavor to seed advances in another. We anticipate that participants will gain an understanding of how a systems biology-based approach can accelerate our knowledge base of multiple sclerosis and how that knowledge base can be successfully applied to novel clinical research and development, as well as potentiated patient care.
CME Information
Multiple sclerosis (MS) is a complex disease in which genetic, environmental and stochastic factors all play a part to induce aberrant interactions between the immune system and neural cells, ultimately transforming into progressive neurological disability. Our understanding of MS is rapidly evolving, and multiple areas of research are showing great promise of future treatment or cure. However, further progress will depend on establishing a deep understanding of the underlying disease mechanisms. With this in mind, this meeting aims to: 1) Define integrated approaches by which to study disease pathogenesis, which represents a critical barrier to progress in the field; 2) Provide an up-to-date perspective on molecular pathogenesis and how this might be used to optimize patient management; 3) Define state-of-the-art technologies by which to quantitate disease burden; 4) Discuss key elements concerning the concept of disease heterogeneity and how emergent approaches to disease stratification can optimize management strategies; and 5) Provide perspectives concerning the potential therapeutic applications of neuroprotective, regenerative and bioengineering-based strategies, and how these might complement immunotherapy. Speakers have been carefully selected on the basis that, independent of whether they are basic scientists or clinician researchers, they each have a track record in adopting a multi-disciplinary approach that has enabled the application of discoveries in one area of endeavor to seed advances in another. We anticipate that participants will gain an understanding of how a systems biology-based approach can accelerate our knowledge base of multiple sclerosis and how that knowledge base can be successfully applied to novel clinical research and development, as well as potentiated patient care.
Conference Program Print | View meeting in 12 hr (am/pm) time
FRIDAY, JANUARY 11
08:00—09:00
Welcome and Keynote Address
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting
*
Trevor J. Kilpatrick,
University of Melbourne, Australia
Lawrence Steinman,
Stanford University, USA
When Bad is Good: Amyloid Molecules as Guardians Against Neuroinflammation
When Bad is Good: Amyloid Molecules as Guardians Against Neuroinflammation
09:00—11:15
Nature and Nurture: Insights Beyond GWAS and Epidemiological Studies
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting
Patrizia Casaccia,
Mount Sinai School of Medicine, USA
Genome-Wide Study of DNA Methylation Reveals Epigenetic Alterations in Brains of Multiple Sclerosis Patients
Genome-Wide Study of DNA Methylation Reveals Epigenetic Alterations in Brains of Multiple Sclerosis Patients
Justin P. Rubio,
GlaxoSmithKline R&D, UK
Realizing the Promise of Pharmacogenomics
Realizing the Promise of Pharmacogenomics
Tomas Olsson,
Karolinska Institutet, Sweden
Genes and Lifestyle/Environmental Factors in Multiple Sclerosis and their Interactions
Genes and Lifestyle/Environmental Factors in Multiple Sclerosis and their Interactions
Judith Field,
University of Melbourne, Australia
Short Talk: Gene Expression in Immune Cell Subsets: A Risk Gene Study for Multiple Sclerosis
Short Talk: Gene Expression in Immune Cell Subsets: A Risk Gene Study for Multiple Sclerosis
17:00—19:15
Cellular and Molecular Profiling: The Road to an Integrated Approach
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting
*
Hartmut Wekerle,
Max Planck Institut, Germany
From Gut to Brain: The Complex Build-Up of Experimental Autoimmune Encephalomyelitis
From Gut to Brain: The Complex Build-Up of Experimental Autoimmune Encephalomyelitis
William H. Robinson,
Stanford University School of Medicine, USA
From Tissue to Proteomics and Lipidomics
From Tissue to Proteomics and Lipidomics
Ronald N. Germain,
NIAID, National Institutes of Health, USA
Using Highly Multiplexed Data Collection and Computational Biology to Probe the Human Immune System
Using Highly Multiplexed Data Collection and Computational Biology to Probe the Human Immune System
Simone C. Wuest,
NINDS, National Institutes of Health, USA
Short Talk: Investigation of Cellular Intrathecal and Peripheral Immune Responses in Patients with Multiple Sclerosis
Short Talk: Investigation of Cellular Intrathecal and Peripheral Immune Responses in Patients with Multiple Sclerosis
Peter Kosa,
NINDS, National Institutes of Health, USA
Short Talk: Exosomes – A Potential Source of Biomarkers in Multiple Sclerosis
Short Talk: Exosomes – A Potential Source of Biomarkers in Multiple Sclerosis
08:00—11:00
Paraclinical Measures of Structural and Functional Change
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting
*
Catherine Lubetzki,
INSERM and University Pierre et Marie Curie (UPMC), France
Elliot M. Frohman,
University of Texas Southwestern Medical Center, USA
Eye-ing a Window of Neuroprotection in the Visual System for MS
Eye-ing a Window of Neuroprotection in the Visual System for MS
Adrienne N. Dula,
Vanderbilt University, USA
Short Talk: Molecular MRI of Multiple Sclerosis Using 7 Tesla Chemical Exchange Saturation Transfer (CEST)
Short Talk: Molecular MRI of Multiple Sclerosis Using 7 Tesla Chemical Exchange Saturation Transfer (CEST)
Paul M. Matthews,
GSK/Imperial College London, UK
Short Talk: Interpreting Molecular Imaging Measures of Inflammation in MS
Short Talk: Interpreting Molecular Imaging Measures of Inflammation in MS
Frauke Zipp,
Johannes-Gutenberg-Universität Mainz, Germany
Crosstalk of the Immune and Nervous Systems
Crosstalk of the Immune and Nervous Systems
Martin Kerschensteiner,
Ludwig Maximilians University Munich, Germany
Harnessing the Potential of Cellular and Molecular in vivo Imaging Techniques
Harnessing the Potential of Cellular and Molecular in vivo Imaging Techniques
17:00—19:00
Immunopathogenesis
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting
*
Lawrence Steinman,
Stanford University, USA
Takashi Yamamura,
National Institute of Neuroscience, NCNP, Japan
Integrating Innate Immunity and Key Environmental Interactions
Integrating Innate Immunity and Key Environmental Interactions
Bahareh Ajami,
Stanford University School of Medicine, USA
Short Talk: Pathological Differences in Th1 and Th17 Mediated Experimental Autoimmune Encephalomyelitis (EAE)
Short Talk: Pathological Differences in Th1 and Th17 Mediated Experimental Autoimmune Encephalomyelitis (EAE)
Stephen D. Miller,
Northwestern University Medical School, USA
Tolerance Induction Using Antigen-Coupled Apoptotic Cells and Biodegradable Nanoparticles for MS Therapy – Mechanisms and Clinical Prospects
Tolerance Induction Using Antigen-Coupled Apoptotic Cells and Biodegradable Nanoparticles for MS Therapy – Mechanisms and Clinical Prospects
08:00—11:00
Clinical Controversies
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting
Jun-ichi Kira,
Kyushu University, Japan
Cutting Edges of Multiple Sclerosis and Neuromyelitis Optica
Cutting Edges of Multiple Sclerosis and Neuromyelitis Optica
*
Brenda Banwell,
University of Pennsylvania, USA
Negotiating Between ADEM, CIS and MS: An Age-Specific Roadmap
Negotiating Between ADEM, CIS and MS: An Age-Specific Roadmap
Judith M. Greer,
University of Queenland, Australia
Short Talk: HLA Alleles Carried by Patients with Multiple Sclerosis Play a Role in Determining the Disease Course and Distribution of Lesions
Short Talk: HLA Alleles Carried by Patients with Multiple Sclerosis Play a Role in Determining the Disease Course and Distribution of Lesions
Timothy Coetzee,
National Multiple Sclerosis Society, USA
CCSVI – Lessons for Funders and the Research Community
CCSVI – Lessons for Funders and the Research Community
17:00—19:00
Clinical Developments
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting
Richard K. Burt,
Northwestern University, USA
Hematopoietic Stem Cell Transplantation for Multiple Sclerosis
Hematopoietic Stem Cell Transplantation for Multiple Sclerosis
*
Richard A. Rudick,
Cleveland Clinic Foundation, USA
Design Issues for Progressive MS Clinical Trials
Design Issues for Progressive MS Clinical Trials
Paul M. Matthews,
GSK/Imperial College London, UK
Treatment Stratification for MS: Opportunities and Challenges
Treatment Stratification for MS: Opportunities and Challenges
Zongqi Xia,
Brigham and Women's Hospital and Harvard Medical School, USA
Short Talk: Leveraging Electronic Health Records for Research in Multiple Sclerosis
Short Talk: Leveraging Electronic Health Records for Research in Multiple Sclerosis
08:00—11:00
Neurobiology
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting
*
Trevor J. Kilpatrick,
University of Melbourne, Australia
Targeting the Oligodendrocyte Lineage in Demyelinative Disease
Targeting the Oligodendrocyte Lineage in Demyelinative Disease
Patrick Kuery,
University of Duesseldorf, Germany
Short Talk: Nucleocytoplasmic Translocation of p57kip2 Promotes Oligodendroglial Differentiation
Short Talk: Nucleocytoplasmic Translocation of p57kip2 Promotes Oligodendroglial Differentiation
Hedwich F. Kuipers,
Stanford University, USA
Short Talk: Differential Roles for the Small Heat Shock Protein Alpha B-Crystallin in Cuprizone-Induced De- and Remyelination
Short Talk: Differential Roles for the Small Heat Shock Protein Alpha B-Crystallin in Cuprizone-Induced De- and Remyelination
Catherine Lubetzki,
INSERM and University Pierre et Marie Curie (UPMC), France
Translational Approaches to Remyelination
Translational Approaches to Remyelination
Peter I. Jukkola,
Ohio State University, USA
Short Talk: K+ Channel Alterations in the Progression of Experimental Autoimmune Encephalomyelitis
Short Talk: K+ Channel Alterations in the Progression of Experimental Autoimmune Encephalomyelitis
17:00—19:00
Cellular Dynamics Underpinning Pathogenesis and Repair
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting
*
Amit Bar-Or,
Montreal Neurological Institute, Canada
Immune:Glial Interactions in MS: Implication during CNS Injury and Repair
Immune:Glial Interactions in MS: Implication during CNS Injury and Repair
Shannon Dunn,
University of Toronto, Canada
Sex Differences in Multiple Sclerosis: Role for Male and Female Pubertal Factors
Sex Differences in Multiple Sclerosis: Role for Male and Female Pubertal Factors
Gianvito Martino,
San Raffaele Scientific Institute, Italy
The Role of Neural Stem Cells in Brain Regeneration
The Role of Neural Stem Cells in Brain Regeneration
*Session Chair †Speaker invited, not yet responded.
Keystone Symposia thanks our Sponsors for generously supporting this meeting:
|
|
We gratefully acknowledge the generous grant for this conference provided by:
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:
Click here to view more of these organizations
|
If your organization is interested in joining these entities in support of Keystone
Symposia, please contact: Melissa Carrera, Assistant
Director of Development, Email: MelissaC@keystonesymposia.org, Phone:+1 970-262-2679 Click here for more information on Industry Support and Recognition Opportunities. If you are interested in becoming an advertising/marketing in-kind partner, please contact: Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org, Phone:+1 970-262-2676 |




