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Granlibakken Resort Floorplan
This meeting took place in 2013
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Meeting Details
New Frontiers in Cardiovascular Genetics Beyond GWAS (A2)
Organizer(s) Jennifer L. Hall and Stephen S. Rich
January 13 - January 18, 2013
Granlibakken Resort • Tahoe City, California USA
Abstract Deadline: September 12, 2012
Late Abstract Deadline: October 25, 2012
Scholarship Deadline: September 12, 2012
Early Registration Deadline: November 12, 2012
Supported by an educational donation provided by Amgen
CME Information
Summary of Meeting:
This meeting will highlight the latest advances in the field and new approaches in genomics and genetics applied to cardiovascular disease and risk factors. Research in the areas of DNA and RNA sequencing and bioinformatics, as it relates to heart failure, sudden cardiac death and coronary artery disease, will be presented from the perspectives of academia and industry around the world. Challenges in the pursuit of translating genetic findings into diagnostic tests and therapies will be discussed by leading experts who have identified new strategies. The sessions feature state-of-the-art talks in genome biology and genome sequencing for guiding medicine decisions, clinical trial designs and tailored medical treatments. This meeting offers a rare and unique opportunity to explore the most current breakthroughs in genetics and personalized medicine from within and outside the field of cardiovascular biology.
CME Information
This meeting will highlight the latest advances in the field and new approaches in genomics and genetics applied to cardiovascular disease and risk factors. Research in the areas of DNA and RNA sequencing and bioinformatics, as it relates to heart failure, sudden cardiac death and coronary artery disease, will be presented from the perspectives of academia and industry around the world. Challenges in the pursuit of translating genetic findings into diagnostic tests and therapies will be discussed by leading experts who have identified new strategies. The sessions feature state-of-the-art talks in genome biology and genome sequencing for guiding medicine decisions, clinical trial designs and tailored medical treatments. This meeting offers a rare and unique opportunity to explore the most current breakthroughs in genetics and personalized medicine from within and outside the field of cardiovascular biology.
Conference Program Print | View meeting in 12 hr (am/pm) time
SUNDAY, JANUARY 13
08:00—09:00
Welcome and Keynote Address
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Jennifer L. Hall,
University of Minnesota, USA
Eric D. Green,
National Human Genome Research Institute, NIH, USA
Entering the Era of Genomic Medicine: Research Opportunities and Challenges
Entering the Era of Genomic Medicine: Research Opportunities and Challenges
09:00—11:30
Breakthroughs in Sequencing and New Approaches in Applications
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting
Leroy E. Hood,
Institute for Systems Biology, USA
Systems Medicine and a Systems Approach to Diseases
Systems Medicine and a Systems Approach to Diseases
Deborah A. Nickerson,
University of Washington, USA
The Next Steps in Sequencing
The Next Steps in Sequencing
Nathan Pearson,
Knome, Inc., USA
Sharing-Enabled Genome Interpretation for Disease at Ingenuity
Sharing-Enabled Genome Interpretation for Disease at Ingenuity
David R. Bentley,
Illumina Cambridge, Ltd., UK
Genomes in Medicine
Genomes in Medicine
17:00—18:15
Discovering Genes, Networks and Function
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*
Emelia J. Benjamin,
Boston University, USA
Richard Bonneau,
New York University, USA
Learning Dynamic Genome-Scale Models of Hematopoietic Stem Cell Differentiation and Function
Learning Dynamic Genome-Scale Models of Hematopoietic Stem Cell Differentiation and Function
Michael J. Flister,
Medical College of Wisconsin, USA
Short Talk: Role of SH2B3 in Genetic Susceptibility to Heart Failure
Short Talk: Role of SH2B3 in Genetic Susceptibility to Heart Failure
08:00—09:00
Keynote Address
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Gary H. Gibbons,
NHLBI, National Institutes of Health, USA
Opportunities in Genomic Science and Genomic Medicine at the National Heart, Lung, and Blood Institute (NHLBI): From Discovery Science to Clinical and Public Health Impact
Opportunities in Genomic Science and Genomic Medicine at the National Heart, Lung, and Blood Institute (NHLBI): From Discovery Science to Clinical and Public Health Impact
09:00—11:30
Genetics of Coronary Artery Disease
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting
Daniel J. Rader,
University of Pennsylvania, USA
Novel Biological Pathways and Therapeutic Targets in Atherosclerosis Revealed through Human Genetics
Novel Biological Pathways and Therapeutic Targets in Atherosclerosis Revealed through Human Genetics
Thomas Quertermous,
Stanford University School of Medicine
Mechanisms Underlying the GWAS Coronary Heart Disease loci
Mechanisms Underlying the GWAS Coronary Heart Disease loci
Kelly A. Frazer,
University of California, San Diego, USA
Identifying and Characterizing Risk Loci for Coronary Artery Disease
Identifying and Characterizing Risk Loci for Coronary Artery Disease
17:00—19:00
Structural Variation
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Marcelo Nobrega,
University of Chicago, USA
Regulatory Networks in Heart Development and Heart Disease
Regulatory Networks in Heart Development and Heart Disease
08:00—08:40
State of the Art in Heart Failure (Bench to Bedside)
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*
Jennifer L. Hall,
University of Minnesota, USA
Heart Failure: Bench to Bedside
Heart Failure: Bench to Bedside
08:40—11:00
State of the Art in Genetics
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Christopher J. O'Donnell,
NHLBI, National Institutes of Health, USA
Translating Genomic Discoveries in Populations towards Understanding, Treating and Preventing Atherosclerotic Cardiovascular Disease
Translating Genomic Discoveries in Populations towards Understanding, Treating and Preventing Atherosclerotic Cardiovascular Disease
Gerald W. Dorn, II,
Washington University School of Medicine, USA
MicroRNAs, Mutations, and the Butterfly Effect
MicroRNAs, Mutations, and the Butterfly Effect
Muredach P. Reilly,
University of Pennsylvania, USA
Transcriptomics of Evoked Inflammation
Transcriptomics of Evoked Inflammation
Bijal Vyas,
Sir Ganga Ram Hospital, India
Short Talk: Molecular Genetic Studies in Families with Life Threatening Cardiac Arrhythmias
Short Talk: Molecular Genetic Studies in Families with Life Threatening Cardiac Arrhythmias
Daniel Steven Herman,
Harvard Medical School
Short Talk: Truncations of the Sarcomere Protein Titin in the General Population
Short Talk: Truncations of the Sarcomere Protein Titin in the General Population
17:00—19:00
Current Updates on DNA, microRNA, and Model Organisms in Heart Disease
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*
Emelia J. Benjamin,
Boston University, USA
The Genetics of Atrial Fibrillation
The Genetics of Atrial Fibrillation
Calum A. MacRae,
Brigham & Women's Hospital, USA
High-Throughput in vivo Exploration of Disease Networks in Zebrafish
High-Throughput in vivo Exploration of Disease Networks in Zebrafish
Manuel Mayr,
King's College, University of London, UK
MicroRNAs within the Continuum of Postgenomics Biomarker Discovery
MicroRNAs within the Continuum of Postgenomics Biomarker Discovery
Jose R. Perez,
Broad Institute, USA
Short Talk: Small Molecule Inducers of TRIB1 Modulate Cholesterol Metabolism in HepG2 cells
Short Talk: Small Molecule Inducers of TRIB1 Modulate Cholesterol Metabolism in HepG2 cells
08:00—11:00
Breakthroughs in Genomics and Personalized Medicine
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*
Howard J. Jacob,
Medical College of Wisconsin, USA
Whole Genome Sequencing: Just Another Clinical Lab Diagnostic?
Whole Genome Sequencing: Just Another Clinical Lab Diagnostic?
Nola Masterson,
Science Futures, Inc., USA
and
and
Martin Reese,
Omicia, Inc., USA
What is Next? Interpreting Genomes at Scale for Clinical Relevance
What is Next? Interpreting Genomes at Scale for Clinical Relevance
Michael R. Bristow,
University of Colorado Anschutz Medical Campus, USA
Pharmacogenetic Targeting of Cardiovascular Drugs
Pharmacogenetic Targeting of Cardiovascular Drugs
Euan A. Ashley,
Stanford University, USA
Short Talk: Systems Approach Identifies the Orphan Receptor Tyrosine Kinase Ros1 as a Mediator of Human Vascular Remodeling
Short Talk: Systems Approach Identifies the Orphan Receptor Tyrosine Kinase Ros1 as a Mediator of Human Vascular Remodeling
Janina M. Jeff,
Vanderbilt University, USA
Short Talk: Fine Mapping the SCN10A Gene Identifies Novel Associations with PR Interval in African Americans
Short Talk: Fine Mapping the SCN10A Gene Identifies Novel Associations with PR Interval in African Americans
17:00—19:00
Difficulties in Going from Genotype to Phenotype
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*
Eric A. Boerwinkle,
University of Texas, USA
Genotype to Phenotype with Hypertension: The Challenges
Genotype to Phenotype with Hypertension: The Challenges
Aravinda Chakravarti,
Johns Hopkins University School of Medicine, USA
From Genome to Function
From Genome to Function
Nicole Soranzo,
Genome Research Limited, UK
Next Generation Association Studies
Next Generation Association Studies
*Session Chair †Speaker invited, not yet responded.
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