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Granlibakken Resort Floorplan

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This meeting took place in 2013



For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

New Frontiers in Cardiovascular Genetics Beyond GWAS (A2)


Organizer(s) Jennifer L. Hall and Stephen S. Rich
January 13—18, 2013
Granlibakken Resort • Tahoe City, California USA
Abstract Deadline: Sep 12, 2012
Late Abstract Deadline: Oct 25, 2012
Scholarship Deadline: Sep 12, 2012
Early Registration Deadline: Nov 12, 2012

Supported by an educational donation provided by Amgen

Summary of Meeting:
This meeting will highlight the latest advances in the field and new approaches in genomics and genetics applied to cardiovascular disease and risk factors. Research in the areas of DNA and RNA sequencing and bioinformatics, as it relates to heart failure, sudden cardiac death and coronary artery disease, will be presented from the perspectives of academia and industry around the world. Challenges in the pursuit of translating genetic findings into diagnostic tests and therapies will be discussed by leading experts who have identified new strategies. The sessions feature state-of-the-art talks in genome biology and genome sequencing for guiding medicine decisions, clinical trial designs and tailored medical treatments. This meeting offers a rare and unique opportunity to explore the most current breakthroughs in genetics and personalized medicine from within and outside the field of cardiovascular biology.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, JANUARY 13

16:00—20:00
Arrival and Registration

18:00—20:00
Light Meal - Provided by Granlibakken


MONDAY, JANUARY 14

07:00—08:00
Breakfast

08:00—09:00
Welcome and Keynote Address
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Stephen S. Rich, University of Virginia, USA

* Jennifer L. Hall, University of Minnesota, USA

Eric D. Green, NHGRI, National Institutes of Health, USA
Entering the Era of Genomic Medicine: Research Opportunities and Challenges

09:00—11:30
Breakthroughs in Sequencing and New Approaches in Applications
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Leroy E. Hood, Institute for Systems Biology, USA
Systems Medicine and a Systems Approach to Diseases

Deborah A. Nickerson, University of Washington, USA
The Next Steps in Sequencing

Nathan Pearson, Knome, Inc., USA
Sharing-Enabled Genome Interpretation for Disease at Ingenuity

David R. Bentley, Illumina Cambridge, Ltd., UK
Genomes in Medicine

09:40—10:00
Coffee Break

11:30—13:00
Poster Setup

Bay
13:00—22:00
Poster Viewing

Bay
11:30—16:30
On Own for Lunch and Recreation

16:30—17:00
Coffee Available

17:00—18:15
Discovering Genes, Networks and Function
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Emelia J. Benjamin, Boston University, USA

Bruce D. Gelb, Mount Sinai Medical Center, USA
Genetic Discovery for Congenital Heart Disease

Richard Bonneau, New York University, USA
Learning Dynamic Genome-Scale Models of Hematopoietic Stem Cell Differentiation and Function

Michael J. Flister, Medical College of Wisconsin, USA
Short Talk: Role of SH2B3 in Genetic Susceptibility to Heart Failure

18:15—19:00
RoundTable Discussion (NIH)

19:00—20:00
Dinner

19:30—22:00
Poster Session 1

Bay
20:00—21:00
Social Hour

Bay

TUESDAY, JANUARY 15

07:00—08:00
Breakfast

08:00—09:00
Keynote Address
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Gary H. Gibbons, NHLBI, National Institutes of Health, USA
Opportunities in Genomic Science and Genomic Medicine at the National Heart, Lung, and Blood Institute (NHLBI): From Discovery Science to Clinical and Public Health Impact

09:00—11:30
Genetics of Coronary Artery Disease
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Daniel J. Rader, University of Pennsylvania, USA
Novel Biological Pathways and Therapeutic Targets in Atherosclerosis Revealed through Human Genetics

Thomas Quertermous, Stanford University School of Medicine
Mechanisms Underlying the GWAS Coronary Heart Disease loci

Kelly A. Frazer, University of California, San Diego, USA
Identifying and Characterizing Risk Loci for Coronary Artery Disease

* Geoffrey S. Ginsburg, Duke University, USA
Advances in Genome Based Cardiovascular Biomarkers

09:20—09:40
Coffee Break

13:00—22:00
Poster Viewing

Bay
11:30—16:30
On Own for Lunch and Recreation

16:30—17:00
Coffee Available

17:00—19:00
Structural Variation
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Stephen S. Rich, University of Virginia, USA
Structural Variants and Risk in Human Disease

Marcelo Nobrega, University of Chicago, USA
Regulatory Networks in Heart Development and Heart Disease

Evan E. Eichler, HHMI/University of Washington, USA
Human Genome Structural Variation and Disease

19:00—20:00
Dinner

20:00—21:00
Social Hour

Bay

WEDNESDAY, JANUARY 16

07:00—08:00
Breakfast

08:00—08:40
State of the Art in Heart Failure (Bench to Bedside)
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Jennifer L. Hall, University of Minnesota, USA
Heart Failure: Bench to Bedside

08:40—11:00
State of the Art in Genetics
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Christopher J. O'Donnell, NHLBI, National Institutes of Health, USA
Translating Genomic Discoveries in Populations towards Understanding, Treating and Preventing Atherosclerotic Cardiovascular Disease

Gerald W. Dorn, II, Washington University School of Medicine, USA
MicroRNAs, Mutations, and the Butterfly Effect

Muredach P. Reilly, University of Pennsylvania, USA
Transcriptomics of Evoked Inflammation

Bijal Vyas, Sir Ganga Ram Hospital, India
Short Talk: Molecular Genetic Studies in Families with Life Threatening Cardiac Arrhythmias

Daniel Steven Herman, Harvard Medical School
Short Talk: Truncations of the Sarcomere Protein Titin in the General Population

09:20—09:40
Coffee Break

13:00—22:00
Poster Viewing

Bay
11:00—16:30
On Own for Lunch and Recreation

16:30—17:00
Coffee Available

17:00—19:00
Current Updates on DNA, microRNA, and Model Organisms in Heart Disease
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Emelia J. Benjamin, Boston University, USA
The Genetics of Atrial Fibrillation

Calum A. MacRae, Brigham & Women's Hospital, USA
High-Throughput in vivo Exploration of Disease Networks in Zebrafish

Manuel Mayr, King's College, University of London, UK
MicroRNAs within the Continuum of Postgenomics Biomarker Discovery

Jose R. Perez, Broad Institute, USA
Short Talk: TRIB1 Inducers and LDL Metabolism

19:00—20:00
Dinner

20:00—21:00
Social Hour

Bay

THURSDAY, JANUARY 17

07:00—08:00
Breakfast

08:00—11:00
Breakthroughs in Genomics and Personalized Medicine
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Howard J. Jacob, Medical College of Wisconsin, USA
Whole Genome Sequencing: Just Another Clinical Lab Diagnostic?

Nola Masterson, Science Futures, Inc., USA
and

Martin Reese, Omicia, Inc., USA
What is Next? Interpreting Genomes at Scale for Clinical Relevance

Michael R. Bristow, University of Colorado Anschutz Medical Campus, USA
Pharmacogenetic Targeting of Cardiovascular Drugs

Euan A. Ashley, Stanford University, USA
Short Talk: Systems Approach Identifies the Orphan Receptor Tyrosine Kinase Ros1 as a Mediator of Human Vascular Remodeling

Janina M. Jeff, Mount Sinai School of Medicine, USA
Short Talk: Fine Mapping the SCN10A Gene Identifies Novel Associations with PR Interval in African Americans

09:20—09:40
Coffee Break

11:00—16:30
On Own for Lunch and Recreation

16:30—17:00
Coffee Available

17:00—19:00
Difficulties in Going from Genotype to Phenotype
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Eric A. Boerwinkle, University of Texas, USA
Genotype to Phenotype with Hypertension: The Challenges

Aravinda Chakravarti, Johns Hopkins University School of Medicine, USA
From Genome to Function

Nicole Soranzo, Genome Research Limited, UK
Next Generation Association Studies

19:00—20:00
Dinner

19:00—20:00
Social Hour

20:00—23:00
Entertainment


FRIDAY, JANUARY 18

 
Departure


*Session Chair †Invited, not yet responded.



Keystone Symposia thanks our Sponsor for generously supporting this meeting:

Educational donation provided by Amgen

We gratefully acknowledge additional support for this conference from:


American Heart Association's Council on Basic Cardiovascular Sciences


American Heart Association's Council on Functional Genomics and Translational Biology

Landes Bioscience

We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13HL115913-01

The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

S. Karger AG - Cardiology

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Amanda Deem, Assistant Director of Development, Email: AmandaD@keystonesymposia.org,
Phone:+1 970-262-2668

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676