Registered Attendees

Registered Attendees

Print This Page

Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online before the meeting...these abstracts will be available in the Abstract Book at the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

Close Window
Granlibakken Resort Floorplan

Granlibakken Resort Floorplan

Print This Page



Close Window

This meeting took place in 2013



For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Growing to Extremes: Cell Biology and Pathology of Axons (C4)


Organizer(s) Valeria Cavalli, Michael Fainzilber and Jeffery L. Twiss
March 10—15, 2013
Granlibakken Resort • Tahoe City, California USA
Abstract Deadline: Nov 8, 2012
Late Abstract Deadline: Dec 10, 2012
Scholarship Deadline: Nov 8, 2012
Early Registration Deadline: Jan 10, 2013

Supported by the Directors' Fund

Summary of Meeting:
Neuronal communication is essential for every movement, sensation and thought in motile animals, and the axonal extensions of neurons provide all long-range communication to, from, and within the brain and spinal cord. Axons extend distances ranging from hundreds of microns to more than a meter in humans, lengths that both require specialized mechanisms for formation and maintenance, and increase the risk of degeneration and dysfunction upon injury or disease. Thus, diverse communities of basic researchers and clinicians must address problems rooted in axonal cell biology, but to date there is no meeting that serves as a central venue for this field. Axon biology meetings in the past have focused on specific sub-topics such as axon guidance, trophic factors, or neurodegeneration. This meeting will bring together the multiple disciplines required for accelerating progress in the field of axonal biology and pathology, providing a unique venue to bring together basic research on molecular and cellular biology of axons with clinical needs and industry interest. The conference will cover a broad spectrum of the latest developments in molecular and cellular axonal research, from development and maintenance, through to survival and repair, in both the central and peripheral nervous systems. Additional topics and late-breaking developments will be incorporated via talks selected from abstracts, specifically encouraging participation of junior researchers and those new to the field. The multidisciplinary theme and shared focus will facilitate communication across the entire continuum from basic to clinical neuroscience.

View Scholarships/Awards

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, MARCH 10

16:00—20:00
Arrival and Registration
18:00—20:00
Light Meal - Provided by Granlibakken
18:00—21:00
Mixer
Drinks available for purchase.


MONDAY, MARCH 11

07:00—08:00
Breakfast
08:00—11:15
Axonal Specification, Cytoskeleton and Compartmentalization
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Valeria Cavalli, Washington University, USA

Frank Bradke, German Center for Neurodegenerative Diseases, Germany
Brain Penetrant Epothilone Reduces Scarring and Induces Axon Growth after Spinal Cord Injury

Matthew N. Rasband, Baylor College of Medicine, USA
The Axon Initial Segment (AIS) and Nodes of Ranvier are Essential for Action Potential Initiation and Propagation

Caterina Tomba, Institut Néel - CNRS, France
Short Talk: Actin Waves in Developing Neurons: Shapes, Mechanical Regulations and Axonal Polarization

* Niels Galjart, Erasmus MC, Netherlands

Franck Polleux, The Scripps Research Institute, USA
LKB1-NUAK1 Kinase Pathway Controls Axon Branching in vivo through Regulation of Presynaptic Mitochondrial Capture

Kozo Kaibuchi, Nagoya University Graduate School of Medicine, Japan
Neuronal Polarity in vitro and in vivo

Pei-Lin Cheng, Institute of Molecular Biology, Academia Sinica, Taiwan
Short Talk: Directional Axoplasmic Transport of Proteasome in Neuronal Polarization

09:20—09:40
Coffee Break
 
On Own for Lunch and Recreation
16:30—17:00
Coffee Available
17:00—19:00
Axonal Growth Modalities
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Nathalie Lamarche-Vane, McGill University, Canada

Michael Fainzilber, Weizmann Institute of Science, Israel
Intrinsic Mechanisms of Axon Growth Control

Douglas H. Smith, University of Pennsylvania, USA
Tension is Good for your Nerves

Giampietro Schiavo, London Research Institute, UK
BICD1 Regulates the Intracellular Sorting and Signaling of Neurotrophin Receptors

Mónica M. Sousa, Instituto de Biologia Molecular e Celular- IBMC, Portugal
Short Talk: Increased Axonal Transport following Conditioning Lesion Underlies Gain of Axonal Regenerative Capacity

19:00—20:00
Dinner
19:00—20:00
Social Hour

TUESDAY, MARCH 12

07:00—08:00
Breakfast
08:00—11:15
Molecular Motors and Axonal Transport Regulation
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Viki J. Allan, University of Manchester, UK

Richard Vallee, Columbia University, USA
Regulation of Cytoplasmic Dynein Transport

Erika L. F. Holzbaur, University of Pennsylvania, USA
Initiation and Regulation of Axonal Transport: Mechanisms of Motor Engagement and Motor Coordination

Chen Gu, Ohio State University, USA
Short Talk: Activation of Conventional Kinesin Motors in Clusters by Shaw Voltage-Gated Potassium Channels

* Caitlin E. Hill, Weill Medical College of Cornell University, USA

Valeria Cavalli, Washington University, USA
Dual Role of HDAC5 in the Regulation of Axon Growth and Regeneration

Frédéric Saudou, Institut Curie, France
Axonal Transport, Energy Supply and…Huntingtin

Glenn F. Rall, Fox Chase Cancer Center, USA
Short Talk: Inter-Neuronal Trafficking of Measles Virus

11:30—12:15
Round Table Discussions with NIH/NINDS Program Directors
Laura Mamounas, NINDS, National Institutes of Health, USA

Robert D. Riddle, NINDS, National Institutes of Health, USA

09:20—09:40
Coffee Break
11:15—13:00
Poster Setup
Bay
13:00—22:00
Poster Viewing
Bay
 
On Own for Lunch and Recreation
14:30—16:30
Workshop
* Jeffery L. Twiss, Drexel University, USA

Bradley T. Lang, Case Western Reserve University, USA
Unlocking Spinal Regeneration and Plasticity: Subcutaneous Injections of a Peptide Inhibitor of PTP-sigma Release CSPG Mediated Axonal Entrapment and Promote Robust Behavioral Recovery following Severe Contusive Spinal Cord Injury

Richard E. Zigmond, Case Western Reserve University, USA
A New Phenotype for the Well Studied Wallerian Degeneration Slow Mouse

Rachel J. Allison, Cambridge Institute for Medical Research, UK
Loss of the Hereditary Spastic Paraplegia Protein Spastin Alters Endosomal Morphology and Trafficking in Non-Polarized Cells and Axons

Nicolas Unsain, Montreal Neurological Institute, Canada
XIAP-Dependent Regulation of Caspase Activity in Degenerating Axons

Biliana O. Veleva-Rotse, Oregon Health & Science University, USA
Pseudokinases Contribute to Axogenesis in the Developing Cerebral Cortex

Bianxiao Cui, Stanford University, USA
The Role of Rab7 in NGF/TrkA Retrograde Signaling

Jung Eun Shin, Washington University, USA
Analysis of SCG10 during Axon Degeneration and Regeneration

Thomas W. Gould, University of Nevada at Reno, USA
Axon Degeneration Induced by Schwann Cell Ablation is Mediated by Activity-Regulated, Muscle-Derived Thrombin

16:30—17:00
Coffee Available
17:00—19:00
Axonal Membrane Dynamics and Organelle Transport
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Eran Perlson, Tel Aviv University, Israel

Britta J. Eickholt, Charité – Universitätsmedizin Berlin, Germany
Spatial and Temporal Control of Neuronal PTEN and Associated Signaling Systems

Rejji Kuruvilla, Johns Hopkins University, USA
Neurotrophin Trafficking in Neuronal Development

Thomas L. Schwarz, Children's Hospital Boston and Harvard Medical School, USA
How Mitochondria Move and Why it Matters to a Neuron

Paul L. McNeil, Georgia Health Sciences University
Short Talk: Promotion of Plasma Membrane Repair by Curcumin: Implications for TBI Therapy

19:00—20:00
Dinner
19:30—22:00
Poster Session 1
Bay
20:00—21:00
Social Hour
Bay

WEDNESDAY, MARCH 13

07:00—08:00
Breakfast
08:00—11:15
RNA Targeting and Local Translation
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* John Houle, Drexel University College of Medicine, USA

Jeffery L. Twiss, Drexel University, USA
mRNAs Compete for Limited Quantities of Axonal Transport Machinery

James Fawcett, University of Cambridge, UK
Why Do CNS Axons Lose the Ability to Regenerate?

Chang-Mei Liu, Johns Hopkins University, USA
Short Talk: SIRT1 and MicroRNA-138 Form a Mutual Negative Feedback Loop to Control Axon Regeneration

* Dianna E. Willis, Burke-Cornell Medical Research Institute, USA

Mustafa Sahin, Children's Hospital Boston, USA
TSC-mTOR Signaling Regulates Axonal mRNA Translation

Gianluca Gallo, Temple University, USA
Short Talk: Embryonic Sensory Axons Exhibit Sites of Preferential mRNA Translation

Ulrich Hengst, Columbia University, USA
Short Talk: A Novel Role for Intra-Axonal Translation in Alzheimer’s Disease

Anne Marion Taylor, University of North Carolina at Chapel Hill, USA
Short Talk: Local Translation of beta-Catenin Regulates Synaptic Vesicle Release Dynamics

09:20—09:40
Coffee Break
11:15—13:00
Poster Setup
Bay
13:00—22:00
Poster Viewing
Bay
 
On Own for Lunch and Recreation
16:30—17:00
Coffee Available
17:00—19:00
Axonal Signaling
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Uwe Drescher, King's College London, UK

David G. Ginty, Johns Hopkins University School of Medicine, USA
The Organization of Neurons that Underlie the Sense of Touch

Gary R. Lewin, Max Delbrück Center for Molecular Medicine, Germany
A Transducosome for the Delivery of Pre-Assembled Mechanotransduction Components for Touch?

Mark H. Tuszynski, University of California, San Diego, USA
Axonal Sprouting and Regeneration in the Central Nervous System

Naoya Yamashita, Johns Hopkins University, USA
Short Talk: A Retrograde Axonal Transport Elicited by Semaphorin3A Drives AMPA Receptor Subunit GluA2 to Dendrites

19:00—20:00
Dinner
19:30—22:00
Poster Session 2
Bay
20:00—21:00
Social Hour
Bay

THURSDAY, MARCH 14

07:00—08:00
Breakfast
08:00—11:15
Axonal Maintenance
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Andres Couve, Universidad de Chile, Chile

Christine E. Beattie, Ohio State University, USA
The Function of the Survival Motor Neuron (SMN) Protein in Motor Axon Development

Avraham Yaron, Weizmann Institute of Science, Israel
Mechanisms of Axonal Maintenance and Degeneration

Takeshi Fujiwara, Osaka University Graduate School of Medicine, Japan
Short Talk: Axonal Transport Proteins Implicated in the Pathology of Alzheimer’s Disease

* Anthony Paul Barnes, Oregon Health & Science University, USA

Joseph W. Lewcock, Genentech, Inc., USA
Intracellular Pathways that Underlie Axon Degeneration in Development and Disease

Guo-li Ming, Johns Hopkins University, USA
Epigenetic Regulation of Axonal Growth

Patrick Lüningschrör, University of Wuerzburg, Germany
Short Talk: Functional Characterization of Plekhgh5 in the Nervous System

09:20—09:40
Coffee Break
 
On Own for Lunch and Recreation
16:30—17:00
Coffee Available
17:00—18:15
Axon-Glia Interactions
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

* Michael Fainzilber, Weizmann Institute of Science, Israel

Klaus-Armin Nave, Max Planck Institute of Experimental Medicine, Germany
Glial Support of Axon Function and Survival

Bruce D. Carter, Vanderbilt University School of Medicine, USA
Mechanisms Regulating Schwann Cell Differentiation and their Pathological Dysregulation

Kelly R. Monk, Washington University School of Medicine, USA
Short Talk: Adhesion-G Protein-Coupled Receptor Signaling in Myelination

18:15—19:15
Closing Keynote Address
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Martin E. Schwab, University of Zürich, Switzerland
Axon Growth and Regeneration: From Basics to Clinic

19:15—20:15
Dinner
19:15—20:15
Social Hour
20:00—23:00
Entertainment

FRIDAY, MARCH 15

 
Departure

*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13NS082038-01

The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.


We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Genentech, Inc.


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Amanda Deem, Assistant Director of Development, Email: AmandaD@keystonesymposia.org,
Phone:+1 970-262-2668

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676