Westin Downtown Denver Floorplan

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This meeting took place in 2015



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Optogenetics (C5)


Organizer(s) Edward S. Boyden, Klaus M. Hahn and Chandra Tucker
March 12—16, 2015
Westin Downtown Denver • Denver, Colorado USA
Discounted Abstract Deadline: Nov 12, 2014
Abstract Deadline: Dec 11, 2014
Scholarship Deadline: Nov 12, 2014
Discounted Registration Deadline: Jan 13, 2015

Supported by the Directors' Fund

Summary of Meeting:
The complexity of biological systems demands tools that enable temporally and spatially precise control of defined signaling pathways. Optogenetics is a new and rapidly evolving field that combines light control with genetic engineering, allowing conditional regulation of signaling processes with seconds and microns precision. Using optogenetic probes, the functions of specific molecules and pathways, the behaviors of individual cells, and the interactions of groups of cells in complex organisms can be precisely interrogated. This symposium seeks to bring together a broad range of researchers developing and using optogenetic probes with those developing related technologies. Specific goals include: 1) To present the latest innovative, genetically-encoded tools and technologies for manipulating biological systems with light; 2) To promote exchange between those developing light-responsive probes and developers of related tools (e.g., biosensors, hardware) that will maximize the power of optogenetics; and 3) To foster the exchange of ideas between optogenetic tool developers and users. This bi-directional feedback has occurred in the neurosciences but not more broadly across biology. No other meeting focuses on these three topics in quite this way. This meeting should facilitate the development and dissemination of a diversity of new optical tools, bring together a diverse but synergistic group of innovators and experimentalists, and ultimately open up new experimental avenues for study that will transform diverse fields.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


THURSDAY, MARCH 12

16:00—20:00
Arrival and Registration

Conference Office C
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

V Lounge

FRIDAY, MARCH 13

07:30—08:30
Breakfast

Augusta
08:30—09:30
Keynote Address
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Platte River Room
Roger Y. Tsien, HHMI/University of California, San Diego, USA
Molecules for Red Light Activation or for Long-Term Memory Storage

09:30—11:45
Optogenetic Engineering I
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Platte River Room
* Peter Hegemann, Humboldt-Universität zu Berlin, Germany

Klaus M. Hahn, University of North Carolina at Chapel Hill, USA
Engineering Proteins for Control and Visualization of Signaling Networks in vivo

Michael Z. Lin, Stanford University School of Medicine, USA
Optogenetics Reunified: Fluorescent Proteins in Optical Sensing of Membrane Voltage and Optical Control of Protein Activity

Ehud Isacoff, University of California, Berkeley, USA
Optical Control of Glutamate Receptor Signaling: Spatio-Temporal Gating of Synaptic Plasticity

Ajith Karunarathne, University of Toledo, USA
Short Talk: Subcellular Optogenetics: Optical Control of Subcellular Signaling and Cell Behavior

10:10—10:30
Coffee Break

Platte River Foyer
11:45—13:00
Poster Setup

Augusta
13:00—22:00
Poster Viewing

Augusta
11:45—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Augusta
17:00—19:00
Structural and Genomic Diversity of Photoreceptor Proteins
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Platte River Foyer
* Kevin H. Gardner, CUNY Advanced Science Research Center, USA

Peter Hegemann, Humboldt-Universität zu Berlin, Germany
Second-Generation Light-Activated Chloride Channels

J. Keith Moffat, University of Chicago, USA
Photoreceptor Control at the Atomic Level

Gane Ka-Shu Wong, University of Alberta, Canada
1000 Plants: Mining Biodiversity for Optogenetics

Udo Heintz, Max Planck Institute for Medical Research, Germany
Short Talk: Blue Light-Induced Dimerization of Aureochrome1a-LOV Enhances the Affinity for its Target DNA Sequence - Crystal Structures Offer New Design Strategies for Optogenetics

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Augusta
19:30—22:00
Poster Session 1
No registration fees are used to fund alcohol served at this function.

Augusta

SATURDAY, MARCH 14

07:30—08:30
Breakfast

Augusta
07:30—08:00
Poster Setup

Augusta
08:00—17:00
Poster Viewing

Augusta
08:30—11:45
Optogenetic Engineering II
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Platte River Room
* Klaus M. Hahn, University of North Carolina at Chapel Hill, USA

Edward S. Boyden, Massachusetts Institute of Technology, USA
Tools for Mapping and Engineering the Brain

Chandra Tucker, University of Colorado Denver, USA
New Cryptochrome Tools for Optical Control

Masayuki Yazawa, Columbia University, USA
Short Talk: Improvement and Applications of FKF1/GI-Based System to Induce Protein-Protein Interactions Using Blue Light

Steven G. Boxer, Stanford University, USA
Light-Directed Dissociation and Association of Split GFP

Andreas Moglich, Humboldt-Universität zu Berlin, Germany
Engineering Light-Responsive Proteins

Anastasia Fomicheva, University of Wyoming, USA
Short Talk: Engineering Near-Infrared Light-Activated Orthologous Drug Systems

09:50—10:10
Coffee Break

Platte River Foyer
11:45—12:30
Lunch

Augusta
12:30—14:30
Poster Session 2

Augusta
16:30—17:00
Coffee Available

Platte River Foyer
17:00—19:00
Optical Control of Biological Processes I
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Platte River Room
* Denise J. Montell, University of California, Santa Barbara, USA

Mathieu Coppey, Institut Curie, France
Spatiotemporal Manipulation of Optogenetic Probes

Matthew J. Kennedy, University of Colorado Denver, USA
Tools for Controlling Neuronal Cell Biology with Light

Jared Toettcher, Princeton University, USA
Using Optogenetics to Dissect Information Processing in Ras/MAPK Signaling

Kristen Lee Witte, University of Chicago, USA
Short Talk: Optogenetic Control of Symmetry Breaking in Saccharomyces cerevisiae

19:00
On Own for Dinner


SUNDAY, MARCH 15

07:30—08:30
Breakfast

Augusta
08:30—11:45
Optical Control of Biological Processes II
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Platte River Room
* Chandra Tucker, University of Colorado Denver, USA

Denise J. Montell, University of California, Santa Barbara, USA
Genetics and Optogenetics Reveal Multiple Distinct Roles for E-cadherin in Coordinating Collective Cell Migration in vivo

Kevin H. Gardner, CUNY Advanced Science Research Center, USA
Nature’s Switches, Biologists’ Tools: Use of LOV Domains to Control Cellular Activities

Keren Lasker, Stanford University, USA
Short Talk: Using Optically Reversible Spatial Mutations to Dissect the Asymmetric Developmental Program of a Bacterium

Brian Kuhlman, University of North Carolina at Chapel Hill, USA
Engineering Improved Switches for Light-Induced Dimerization and Light-Conditioned Nuclear Translocation

Viviana Gradinaru, California Institute of Technology, USA
Visualizing the Activity and Anatomy of Brain Circuits: Optogenetic Sensors and Tissue-Clearing Approaches

Spencer T. Glantz, University of Pennsylvania, USA
Short Talk: Comprehensive Analysis of the Functional Diversity of LOV Domain Proteins

09:50—10:10
Coffee Break

Platte River Foyer
11:45—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Platte River Foyer
17:00—19:00
Optical Control of Biological Processes III
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Platte River Room
* Edward S. Boyden, Massachusetts Institute of Technology, USA

Valentina Emiliani, Paris Descartes University, France
Optogenetics and Wave Front Shaping

Xue Han, Boston University, USA
Technologies for Analyzing Neural Circuits of Brain Disorders

Ariel E. Hight, Harvard University, USA
Short Talk: Spatially Restricted Optogenetic Stimulation of the Central Auditory System in an Auditory Brainstem Implant Model

Seung-Hee Lee, Korea Advanced Institutes of Science and Technology, KAIST, South Korea
Short Talk: Virtual Perception Induced by Optogenetic Stimulation of Mouse Sensory Cortices

Emil B. Kromann, Yale University, USA
Short Talk: Optogenetics Meets Nanoscale Fluorescence Imaging

19:00—19:15
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Platte River Room
19:15—20:30
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Augusta
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Augusta

MONDAY, MARCH 16

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge additional support for this conference from:


Intelligent Imaging Innovations (3i)

Chroma Technology Corporation

We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13NS090878-01

The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.


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