Clarion Hotel Sign Floorplan

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This meeting took place in 2015


Here are the related meetings in 2017:
Omics Strategies to Study the Proteome (A8)

For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

The Human Proteome (D7)


Organizer(s) Matthias Mann, Mathias Uhlén, Catherine E. Costello and Albert J.R. Heck
April 24—29, 2015
Clarion Hotel Sign • Stockholm, Sweden
Discounted Abstract Deadline: Dec 22, 2014
Abstract Deadline: Jan 27, 2015
Scholarship Deadline: Dec 22, 2014
Discounted Registration Deadline: Feb 24, 2015

Organized in collaboration with Knut and Alice Wallenberg Foundation and Science for Life Laboratory - Stockholm. Sponsored by Thermo Fisher Scientific Inc.

Summary of Meeting:
The 2015 Symposium on The Human Proteome follows the very successful 2012 Keystone meeting in the same location in Sweden. As before, we have made every effort to present proteomics research of outstanding excellence and current scientific interest. Unlike the previous meeting, this one has a defining and topical theme: The completion of the human proteome. In fact, the date and venue are chosen, in part, because they coincides with the completion of the Human Protein Atlas, a very large undertaking to generate antibodies and localization information for all human protein coding regions. This event also coincides with the expected completion of complete proteome measurements of mammalian cells by mass spectrometry-based proteomics, which will be a major highlight of the conference and attract not only scientific but also media interest. Two sessions will be dedicated to covering the completion of human proteome, encompassing the leading researchers engaged with this important topic. Further sessions are dedicated to the rapid advances in mass spectrometric technology in proteomics. Complementing these advances, one session will deal with the analysis of intact proteins. Further topics represented are interaction proteomics and post-translational modifications. Related topics such as network analysis, crosslinking and of course conceptually novel applications of proteomics in cell biology and biomedicine will round off the program. Given the quality of the invited speakers and the breakthrough presentations, we expect the 2015 Keystone Symposium on The Human Proteome to be the scientifically most exciting event in this field.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


FRIDAY, APRIL 24

16:00—20:00
Arrival and Registration

Foyer
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Foyer

SATURDAY, APRIL 25

07:30—08:30
Breakfast

Individual Hotel
08:30—09:30
Welcome and Keynote Address
Meeting has ended...abstracts no longer viewable online.

B1/B2
* Mathias Uhlén, Royal Institute of Technology, Sweden
Opening of the Meeting

* Matthias Mann, Max Planck Institute of Biochemistry, Germany
Introduction of the Keynote Address

Vishva M. Dixit, Genentech, Inc., USA
Proteomics in Drug Target Identification, Oncology and Immunology

09:30—12:00
Completion of the Human Proteome I
Meeting has ended...abstracts no longer viewable online.

B1/B2
* Albert J. R. Heck, Utrecht University, Netherlands

Mathias Uhlén, Royal Institute of Technology, Sweden
Completing the Human Protein Atlas

Rudolf H. Aebersold, Institute of Molecular Systems Biology, ETH Zürich, Switzerland
Quantifying Proteotypes

Matthias Mann, Max Planck Institute of Biochemistry, Germany
Large-Scale Proteomics Moves to the Clinic

Anthony W. Purcell, Monash University, Australia
Short Talk: An Immune-Centric View of the Human Proteome

Jens S. Andersen, University of Southern Denmark, Denmark
Short Talk: Centrosomes and Centriolar Satellites Associate with Negative Regulators of Innate Immune Signaling

10:10—10:30
Coffee Break

Foyer/B3
12:00—13:00
Poster Setup

B3
13:00—22:00
Poster Viewing

B3
12:00—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Foyer/B3
17:00—19:00
Advances in the Technology of Mass Spectrometry-Based Proteomics
Meeting has ended...abstracts no longer viewable online.

B1/B2
* Ralph A. Bradshaw, University of California-Irvine, USA

Alexander Makarov, Thermo Fisher, Germany
Orbitrap Mass Spectrometry for Proteomics

Juergen Cox, Max Planck Institute for Biochemistry, Germany
Controlling False Discovery Rates (FDRs) in Genome-Wide Proteomics Datasets

Joshua J. Coon, University of Wisconsin, USA
One-Hour Proteomes and Deep Sequencing

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

B3/Atrium
19:30—22:00
Poster Session 1

B3

SUNDAY, APRIL 26

07:30—08:30
Breakfast

Individual Hotel
08:30—11:45
Signaling and Post-Translational Modification
Meeting has ended...abstracts no longer viewable online.

B1/B2
* Maxey C.M. Chung, National University of Singapore, Singapore

Catherine E. Costello, Boston University School of Medicine, USA
Applications of Glycomic Strategies for the Analysis of Biologically Significant Glycoproteins

Jesper V. Olsen, University of Copenhagen, Denmark
Phosphoproteomics in Cells and in Tissues

Emma Lundberg, SciLifeLab Stockholm and School of Biotechnology, KTH, Sweden
Subcellular Localization of the Human Proteome

Misha Savitski, Cellzome GmbH, Germany
Tracking Cancer Drugs in Living Cells by Thermal Profiling of the Proteome

Neil G. Rumachik, Stanford University, USA
Short Talk: Protein O-GlcNAcylation Oscillates and Acts as a Nutrient Sensor during Neural Differentiation of Human Embryonic Stem Cells

Alfred Vertegaal, Leiden University Medical Center, Netherlands
Short Talk: Uncovering Dynamic Small Ubiquitin-Like Modifier Signaling Networks in a Site-Specific Manner

09:50—10:10
Coffee Break

Foyer/B3
11:45—13:00
Poster Setup

B3
13:00—22:00
Poster Viewing

B3
11:45—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Foyer/B3
17:00—19:15
Clinical and Drug-Related Proteomics
Meeting has ended...abstracts no longer viewable online.

B1/B2
* Ileana M. Cristea, Princeton University, USA

Philipp Mertins, Broad Institute of MIT and Harvard, USA
Proteogenomic and Phosphoproteomic Analysis of Breast Cancer

Christie L. Hunter, AB SCIEX, USA
Large-Scale Targeted Quantitative Proteomics for Biomarker Research

Tamar Geiger, Tel Aviv University, Israel
Genome-Scale Proteomic Profiling of Breast Cancer Progression

Wendy Sandoval, Genentech, Inc., USA
Short Talk: High-Resolution Mass Spectrometric Characterization of Chain Pairing Variants in Co-Expressed Bispecific Antibody Production under Native and Acidic Conditions

Simone Lemeer, Utrecht University, Netherlands
Short Talk: Elucidating Small Molecule Inhibitor Resistance in Lung Cancer

19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

B3/Atrium
19:30—22:00
Poster Session 2

B3

MONDAY, APRIL 27

07:30—08:30
Breakfast

Individual Hotel
08:30—11:45
Interaction Proteomics
Meeting has ended...abstracts no longer viewable online.

B1/B2
* Catherine E. Costello, Boston University School of Medicine, USA

Anne-Claude Gingras, Lunenfeld-Tanenbaum Research Institute, Canada
A Physical Map of a Human Cell

Jun Qin, Baylor College of Medicine, USA
Towards Comprehensive Analysis of Endogenous Protein Interactions

Christine Vogel, New York University, USA
Protein Expression Dynamics in Mammalian Cells Responding to Environmental Stress

Ileana M. Cristea, Princeton University, USA
The Impact of Protein Interaction Studies on Discovering Host Defense Factors during Viral Infections

Evangelia Petsalaki, Lunenfeld-Tanenbaum Research Institute, Canada
Short Talk: Barcode-Fusion Genetics Yeast-Two Yybrid (BFG-Y2H): Toward a Multidimensional Protein Interaction Map

Georg Kustatscher, Wellcome Trust Centre for Cell Biology, University of Edinburgh, UK
Short Talk: Chromatin Factors Mapped by Co-Regulation Patterns in Proteomic Experiments

09:50—10:10
Coffee Break

Foyer/B3
11:45—13:00
Poster Setup

B3
13:00—22:00
Poster Viewing

B3
11:45—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Foyer/B3
17:00—19:15
Networks and Cross-Linking
Meeting has ended...abstracts no longer viewable online.

B1/B2
* Tamar Geiger, Tel Aviv University, Israel

Lars Juhl Jensen, University of Copenhagen, Denmark
In silico and Text-Based Analysis of Cellular Networks

Yasushi Ishihama, Kyoto University, Japan
Chromatographic Challenges Facing Complete Human Proteome and Phosphoproteome Analysis

Juri Rappsilber, Wellcome Trust Centre, University of Edinburgh, UK
Protein Structure Determination in Biological Matrices by Mass Spectrometry and Computational Biology

Franz Herzog, Gene Center Munich, Germany
Short Talk: Insights into Chromatin Assembled Protein Complexes by Cross-Link Driven Hybrid Structural Biology

Jeroen Krijgsveld, EMBL, Germany
Short Talk: Novel Approaches to Investigate Global and Locus-Specific Chromatin Composition

19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

B3/Atrium
19:30—22:00
Poster Session 3

B3

TUESDAY, APRIL 28

07:30—08:30
Breakfast

Individual Hotel
08:30—11:45
Completion of the Human Proteome II
Meeting has ended...abstracts no longer viewable online.

B1/B2
* Ronald Hendrickson, Memorial Sloan Kettering Cancer Center, USA

Alexander Fields, University of California, San Francisco, USA
Quantitative and Global Monitoring of Protein Translation with Ribosome Profiling

Bernhard Küster, Technische Universität München, Germany
Human Proteomes: From Basic Science to Understanding Drug Action

Jun Wang, Beijing Genome Institute, China
Million Genomes Ahead

Angus I. Lamond, University of Dundee, UK
Multidimensional Analysis of Human Proteome Dynamics

Karsten Krug, University of Tuebingen, Germany
Short Talk: Assessing the Influence of Modified Non-Synonymous Single Nucleotide Variants on Signal Transduction Networks in Human Proteome

Petra Van Damme, University of Ghent, Belgium
Short Talk: Study of N-Terminal Proteoform Diversity by N-Terminomics and Ribosome Profiling

09:50—10:10
Coffee Break

Foyer/B3
11:45—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Foyer/B3
17:00—18:45
Mass Spectometry-Based Proteomics of Intact Proteins
Meeting has ended...abstracts no longer viewable online.

B1/B2
* Anne-Claude Gingras, Lunenfeld-Tanenbaum Research Institute, Canada

Neil L. Kelleher, Northwestern University, USA
A Top Down Approach to the Human Proteome Project: Has the Time Now Come?

Albert J. R. Heck, Utrecht University, Netherlands
Protein-Protein Reaction Monitoring by Native Mass Spectrometry

Michal Sharon, Weizmann Institute of Science, Israel
Discovering a New Subunit for an Old Complex

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Meeting has ended...abstracts no longer viewable online.

B1/B2
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

B3
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

B3

WEDNESDAY, APRIL 29

 
Departure


*Session Chair †Invited, not yet responded.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Knut and Alice Wallenberg Foundation Science for Life Laboratory - Stockholm
Thermo Fisher Scientific Inc.
 

We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge additional support for this conference from:

Cambridge Isotope Laboratories, Inc. Cell Signaling Technology, Inc.

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



AB SCIEX


Genentech, Inc.


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Assistant Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676