Registered Attendees

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Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online before the meeting...these abstracts will be available in the Abstract Book at the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

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Casa Grande Hotel Floorplan

Casa Grande Hotel Floorplan

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NOTES:
This meeting will be conducted in English.

All programs are subject to change. Check this site for updates.


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Cell Death Signaling in Cancer and the Immune System (S2)

Scientific Organizers: Gustavo Amarante-Mendes, Douglas R. Green and Kim Newton


October 28—November 2, 2014

Casa Grande Hotel, Guaruja, São Paulo, Brazil


Organized in collaboration with the São Paulo Research Foundation (FAPESP) and the National Council for Scientific and Technological Development (CNPq) - Brazil. Sponsored by AbbVie Inc., Genentech, Inc. and TESARO, Inc.


IT’S NOT TOO LATE TO SUBMIT YOUR ABSTRACT. Abstracts received can no longer be considered for oral short talks; poster display opportunities remain open.
DEADLINES:
Travel Award Deadline: Jul 10, 2014 [details]
Scholarship Deadline: Jun 26, 2014 [details]
Discounted Abstract Deadline: Jun 26, 2014 [details]
Abstract Deadline: Jul 29, 2014 [details]
Discounted Registration Deadline: Aug 28, 2014 [details]

Submit an Abstract Register Yourself Deadlines and Fees
Deadlines and Fees for 2015-S2 ''Cell Death Signaling in Cancer and the Immune System''
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Rates and Deadlines listed below are for the 2015-S2 "Cell Death Signaling in Cancer and the Immune System" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On June 26, 2014 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After June 26, 2014 until August 28, 2014 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
June 26, 2014 n/a
Discounted NON-STUDENT Registration
More details
Before and On August 28, 2014 775.00 USD
(includes 150.00 discount)
Regular NON-STUDENT Registration
More details
After August 28, 2014 925.00 USD
Discounted STUDENT Registration
More details
Before and On August 28, 2014 550.00 USD
(includes 150.00 discount)
Regular STUDENT Registration
More details
After August 28, 2014 700.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will    accept no liability for money loss through bank charges, transfers or currency fluctuations.

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About Discounted Abstract Deadline
About Global Health Travel Award Deadline
About Scholarship Deadline
About Abstract Deadline
About Discounted Registration Deadline

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


TUESDAY, OCTOBER 28

16:00—20:00
Arrival and Registration

Imperial Ballroom Foyer
18:00—20:00
Mixer

Imperial Ballroom Terrace

WEDNESDAY, OCTOBER 29

07:30—08:30
Breakfast

Individual Hotel
08:30—09:30
Keynote Address
Registered attendees can view abstracts starting on 09/28/2014

Imperial Ballroom
Vishva M. Dixit, Genentech, Inc., USA
Interplay Between NOD Sensors that Mediated Pyroptosis

09:30—12:00
Cell Death Signaling I
Registered attendees can view abstracts starting on 09/28/2014

Imperial Ballroom
Guy S. Salvesen, Sanford-Burnham Medical Research Institute, USA
Caspases and Substrates in Cell Fate Decisions

Mohanish Deshmukh, University of North Carolina at Chapel Hill, USA
How Cells Evade Apoptosis: from Neurons to Cancer

Douglas R. Green, St. Jude Children's Research Hospital, USA
How Cells Survive: Single Cell Analysis Reveals Properties of Non-Genetic Apoptosis Resistance

Marion MacFarlane†, MRC Toxicology Unit, UK
Short Talk: c-FLIP-Mediated Regulation of Caspase-8 DED Chain Assembly Determines Cell Fate

Stefan J. Riedl, Sanford|Burnham Medical Research Institute, USA
Short Talk: Structure and Mechanism: Death Domains in the Regulation of Immunity and Cancer

10:10—10:30
Coffee Break

Imperial Ballroom Terrace
12:00—13:00
Poster Setup

Imperial Ballroom
12:00—14:30
On Own for Lunch

13:00—22:00
Poster Viewing

Imperial Ballroom
14:30—16:30
Workshop 1: Cancer

Imperial Ballroom
Peter Huebener, University Hospital Hamburg-Eppendorf, Germany
HMGB1 Links Chronic Injury and Cancer in the Liver

Keehoon Jung, Harvard Medical School / MGH, USA
Targeting the Immune Microenvironment to Improve Colorectal Cancer Treatment

Nga Lam, Walter and Eliza Hall Institute, Australia
Understanding the Role of Bcl-G in Cell Death Signaling And Colorectal Cancer

Yannick Boege†, UniversityHospital Zurich, Switzerland
An Apoptosis-Driven Pathway to Hepatocarcinogenesis

Hetal Brahmbhatt, McMaster University, Canada
Identification and Characterization of Small Molecules that Enhance the Pro-Apoptotic Activity of Bax

Stephen E. Girardin, University of Toronto, Canada
The Mitochondrial Protein NLRX1 Controls the Balance between Extrinsic and Intrinsic Apoptosis

Gabriel Ichim, Beatson Institute, UK
Limited Mitochondrial Permeabilisation causes DNA-Damage and Genomic Instability in the Absence of Cell Death

Fabien Llambi, St. Jude Children's Research Hospital, USA
BOK is a Pro-Apoptotic Effector Protein Regulated by the Ubiquitin-Proteasome System

16:30—17:00
Coffee Available

Imperial Ballroom Terrace
17:00—19:00
Cell Death Signaling II
Registered attendees can view abstracts starting on 09/28/2014

Imperial Ballroom
Beth Levine, University of Texas Southwestern Medical Center, USA
Autophagic Cell Death

Peter Vandenabeele, VIB, Ghent University, Belgium
Necroptosis versus Apoptosis

Francis Ka-Ming Chan, University of Massachusetts Medical School, USA
Molecular Regulation of Necroptosis in Anti-Viral and Sterile Inflammation

Silvia Alvarez-Diaz, Walter and Eliza Hall Institute, Australia
Short Talk: MLKL Plays a Critical Role Inducing Necroptosis within a Physiological Context

19:00—20:00
Social Hour with Lite Bites

Imperial Ballroom Terrace
19:30—22:00
Poster Session 1

Imperial Ballroom

THURSDAY, OCTOBER 30

07:30—08:30
Breakfast

Individual Hotel
08:30—11:45
Cell Death and Cancer I
Registered attendees can view abstracts starting on 09/28/2014

Imperial Ballroom
Andreas E. Strasser, Walter and Eliza Hall Institute of Medical Research, Australia
How Does p53 Prevent Cancer?

David W. Andrews, University of Toronto, Canada
Regulation of Mitochondrial Membrane Permeabilization by Bcl-2 Family Proteins

Gerry Melino, University of Rome ‘Tor Vergata’, Italy
Control of Cell Fate by miRNA

Ruslan M. Medzhitov, HHMI/Yale University School of Medicine, USA
Cellular Cooperation in Normal Tissues and Tumors

Stephen W. Fesik, Vanderbilt University School of Medicine, USA
Short Talk: Mcl-1 Inhibitors for the Treatment of TNBC and Other Cancers

Axel Witt, University Hospital Cologne, Germany
Short Talk: IAP Antagonization Induces Inflammatory Destruction of Vasculature Endothelium and Inhibits Tumor Growth

09:50—10:10
Coffee Break

Imperial Ballroom Terrace
11:45—13:00
Poster Setup

Imperial Ballroom
11:45—14:30
On Own for Lunch

13:00—22:00
Poster Viewing

Imperial Ballroom
14:30—16:30
Workshop 2: Host Defense

Imperial Ballroom
Goutam Gupta†, Los Alamos National Laboratory, USA
Preventing Host Cell Death by Engineering of Novel Innate Immune Defense

Luciana Paroneto Medina, ICB-USP, Brazil
PGE2 as a Regulator of Experimental Autoimmune Encephalomyelitis (EAE)

Maria Andree, University of Cologne, Germany
BID-Dependent Release of Mitochondrial SMAC Dampens XIAP-Mediated Immunity Against Shigella

Dmitry M. Shayakhmetov, Emory University, USA
The Identification of the Novel Physiologically-Regulated Necrotic Cell Death Pathway Mediated by the Interferon-Regulatory Factor 3 (IRF3)

Rahul S. Shinde†, Georgia Regents University, USA
IDO1 Inhibits B Cell Survival and Antibody Production to T Independent Antigens

Eugenio D. Hottz†, Oswaldo Cruz Foundation, Brazil
Mitochondria-Mediated Activation of Inflammasome and Cell Death Pathways in Platelets Modulate Inflammatory Responses in Dengue

Bernardo Simões Franklin†, Institute of Innate Immunity/University of Bonn, Germany
The Extracellular Functions of the Inflammasomes

Jennifer Martinez, St. Jude Children's Research Hospital, USA
LC3-Associated Phagocytosis as a Critical Regulator of Inflammation

16:30—17:00
Coffee Available

Imperial Ballroom Terrace
17:00—19:00
Cell Death and Cancer II
Registered attendees can view abstracts starting on 09/28/2014

Imperial Ballroom
Gerard I. Evan, University of Cambridge, UK
Killing Cancers without Killing Normal Tissues

Karen H. Vousden, Beatson Institute for Cancer Research, UK
Metabolic Control of Cancer Cell Fate Decisions

Anthony G. Letai, Dana-Farber Cancer Institute, USA
Kicking Cancer Right in the Mitochondria

Andreas Bergmann, University of Massachusetts Medical School, USA
Short Talk: Autophagy Regulates Tissue Overgrowth in a Context-Dependent Manner

19:00—20:00
Social Hour with Lite Bites

Imperial Ballroom Terrace
19:30—22:00
Poster Session 2

Imperial Ballroom

FRIDAY, OCTOBER 31

07:30—08:30
Breakfast

Individual Hotel
08:30—11:45
Cell Death and Host Defense I
Registered attendees can view abstracts starting on 09/28/2014

Imperial Ballroom
Herbert W. Virgin, Washington University School of Medicine, USA
Role of Autophagy Genes in Inflammation and Immunity through Effects on Cell Survival and Basal Innate Immune Tone

Petr Broz, Biozentrum, University of Basel, Switzerland
Caspase-11 Activation Requires Lysis of Pathogen-Containing Vacuoles by IFN-Induced GTPases

Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital, USA
Inflammasome Control of Disease

Karina R. Bortoluci, Federal University of São Paulo, Brazil
Lysosomal Pathway Induced by Cytosolic Flagellin in Cell Death and Immunity

Domagoj Vucic, Genentech, Inc., USA
Short Talk: IAP Proteins Regulate the Formation of Necrosome and Inflammasome Complexes

Igor E. Brodsky, University of Pennsylvania, USA
Short Talk: RIPK1 and Caspase-8 Catalytic Activity Mediate Caspase-1 Activation in Response to Pathogen Blockade of Innate Immune Signaling

09:50—10:10
Coffee Break

Imperial Ballroom Terrace
11:45—13:00
Poster Setup

Imperial Ballroom
11:45—17:00
On Own for Lunch

13:00—22:00
Poster Viewing

Imperial Ballroom
16:30—17:00
Coffee Available

Imperial Ballroom Terrace
17:00—19:00
Cell Death and Host Defense II
Registered attendees can view abstracts starting on 09/28/2014

Imperial Ballroom
Janelle S. Ayres, The Salk Institute, USA
Microbiota Control of Infection and Inflammation Induced Pathology

Gustavo P. Amarante-Mendes, Universidade de São Paulo, Brazil
Short Talk: Novel Players of Cytotoxic Cell Killing

Seamus J. Martin, Trinity College Dublin, Ireland
Inflammatory Outcomes of Divergent Cell Death Modalities

Avi Ashkenazi, Genentech, Inc., USA
Opposing UPR Signals Converge on DR5 to Control Apoptosis

19:00—20:00
Social Hour with Lite Bites

Imperial Ballroom Terrace
19:30—22:00
Poster Session 3

Imperial Ballroom

SATURDAY, NOVEMBER 1

07:30—08:30
Breakfast

Individual Hotel
08:30—11:45
Consequences of Cell Death
Registered attendees can view abstracts starting on 09/28/2014

Imperial Ballroom
Shigekazu Nagata, Kyoto University, Japan
Exposure of Phosphatidylserine and Engulfment of Dead and Living Cells

Kim Newton, Genentech, USA
Necroptosis Signaling and Inflammation

Will Wood, University of Bristol, UK
Signal Prioritization: Recognizing Death and Damage in vivo

Eric H. Baehrecke, University of Massachusetts Medical School, USA
Inflammatory Signaling, Autophagy and Dying Cell Clearance

Andrew Oberst, Oberst, USA
Short Talk: Inflammatory and Immune Responses to Apoptosis and Necroptosis

Linda Julian, Beatson Institute for Cancer Research, UK
Short Talk: Apoptotic Blebbing in Tissue Homeostasis and Cancer

09:50—10:10
Coffee Break

Imperial Ballroom Terrace
11:45—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Imperial Ballroom Terrace
17:00—18:15
Cell Death Therapies
Registered attendees can view abstracts starting on 09/28/2014

Imperial Ballroom
Simone Fulda, University Hospital Frankfurt, Germany
Novel Opportunities to Target IAP Proteins for Cancer Therapy

David Ching Huang, Walter and Eliza Hall Institute of Medical Research, Australia
Therapeutically Targeting the Bcl-2-Regulated Cell Survival Pathway

18:15—19:15
Closing Keynote Address
Registered attendees can view abstracts starting on 09/28/2014

Imperial Ballroom
Scott W. Lowe, HHMI/Memorial Sloan-Kettering Cancer Center, USA
Tumor Suppressor and Tumor Maintenance Genes

19:15—20:15
Social Hour with Lite Bites

Imperial Ballroom
20:00—23:00
Entertainment

Imperial Ballroom

SUNDAY, NOVEMBER 2

 
Departure


*Session Chair †Speaker invited, not yet responded.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

AbbVie Inc. Genentech, Inc.

National Council for Scientific and Technological Development (CNPq) - Brazil

São Paulo Research Foundation (FAPESP) - Brazil
TESARO, Inc.
 

We gratefully acknowledge additional support for this conference from:

Cell Signaling Technology, Inc.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Amanda Deem, Assistant Director of Development, Email: AmandaD@keystonesymposia.org,
Phone:+1 970-262-2668

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676