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Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online before the meeting...these abstracts will be available in the Abstract Book at the meeting.

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Casa Grande Hotel Floorplan

Casa Grande Hotel Floorplan

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NOTES:
This meeting will be conducted in English.

All programs are subject to change. Check this site for updates.


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Twitter hashtag for this meeting: #KScelldeath

Cell Death Signaling in Cancer and the Immune System (S2)

Scientific Organizers: Gustavo Amarante-Mendes, Douglas R. Green and Kim Newton


October 28—November 2, 2014

Casa Grande Hotel, Guarujá, São Paulo, Brazil


Organized in collaboration with the São Paulo Research Foundation (FAPESP) and the National Council for Scientific and Technological Development (CNPq) - Brazil. Sponsored by AbbVie Inc., Genentech, Inc. H3 Biomedicine Inc. and TESARO, Inc.


Abstract submission is closed. Registered attendees can bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested. DEADLINES:
Travel Award Deadline: Jul 10, 2014 [details]
Scholarship Deadline: Jun 26, 2014 [details]
Discounted Abstract Deadline: Jun 26, 2014 [details]
Abstract Deadline: Jul 29, 2014 [details]
Discounted Registration Deadline: Aug 28, 2014 [details]

Register Yourself Deadlines and Fees
Deadlines and Fees for 2015-S2 ''Cell Death Signaling in Cancer and the Immune System''
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Rates and Deadlines listed below are for the 2015-S2 "Cell Death Signaling in Cancer and the Immune System" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On June 26, 2014 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After June 26, 2014 until August 28, 2014 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
June 26, 2014 n/a
Discounted NON-STUDENT Registration
More details
Before and On August 28, 2014 775.00 USD
(includes 150.00 discount)
Regular NON-STUDENT Registration
More details
After August 28, 2014 925.00 USD
Discounted STUDENT Registration
More details
Before and On August 28, 2014 550.00 USD
(includes 150.00 discount)
Regular STUDENT Registration
More details
After August 28, 2014 700.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will    accept no liability for money loss through bank charges, transfers or currency fluctuations.

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About Discounted Abstract Deadline
About Global Health Travel Award Deadline
About Scholarship Deadline
About Abstract Deadline
About Discounted Registration Deadline

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


TUESDAY, OCTOBER 28

16:00—20:00
Arrival and Registration

18:00—19:00
Mixer


WEDNESDAY, OCTOBER 29

07:30—08:30
Breakfast

08:30—09:30
Keynote Address
Registered attendees can view abstracts starting on 09/28/2014

* Douglas R. Green, St. Jude Children's Research Hospital, USA

Vishva M. Dixit, Genentech, Inc., USA
Interplay between NOD Sensors that Mediated Pyroptosis

09:30—12:00
Cell Death Signaling I
Registered attendees can view abstracts starting on 09/28/2014

* Seamus J. Martin, Trinity College Dublin, Ireland

Guy S. Salvesen, Sanford-Burnham Medical Research Institute, USA
A Toolbox of Highly Selective Caspase Chemical Reagents

Mohanish Deshmukh, University of North Carolina at Chapel Hill, USA
How Cells Evade Apoptosis: From Neurons to Cancer

Marion MacFarlane, MRC Toxicology Unit, UK
Short Talk: c-FLIP-Mediated Regulation of Caspase-8 DED Chain Assembly Determines Cell Fate

Stefan J. Riedl, Sanford-Burnham Medical Research Institute, USA
Short Talk: Structure and Mechanism: Death Domains in the Regulation of Immunity and Cancer

Douglas R. Green, St. Jude Children's Research Hospital, USA
How Cells Survive: Single Cell Analysis Reveals Properties of Non-Genetic Apoptosis Resistance

10:10—10:30
Coffee Break

12:00—13:00
Poster Setup

12:00—14:30
On Own for Lunch

13:00—22:00
Poster Viewing

14:30—16:30
Workshop 1: Cancer

* David W. Andrews, University of Toronto, Canada

Peter Huebener, University Hospital Hamburg-Eppendorf, Germany
HMGB1 Links Chronic Injury and Cancer in the Liver

Keehoon Jung, Harvard Medical School, Massachusetts General Hospital, USA
Targeting the Immune Microenvironment to Improve Colorectal Cancer Treatment

Nga Lam, Walter and Eliza Hall Institute, Australia
Understanding the Role of Bcl-G in Cell Death Signaling And Colorectal Cancer

Yannick Böge, University Hospital Zürich, Switzerland
An Apoptosis-Driven Pathway to Hepatocarcinogenesis

Hetal Brahmbhatt, McMaster University, Canada
Identification and Characterization of Small Molecules that Enhance the Pro-Apoptotic Activity of Bax

Stephen E. Girardin, University of Toronto, Canada
The Mitochondrial Protein NLRX1 Controls the Balance between Extrinsic and Intrinsic Apoptosis

Gabriel Ichim, Beatson Institute, UK
Limited Mitochondrial Permeabilisation Causes DNA-Damage and Genomic Instability in the Absence of Cell Death

Fabien Llambi, St. Jude Children's Research Hospital, USA
BOK is a Pro-Apoptotic Effector Protein Regulated by the Ubiquitin-Proteasome System

16:30—17:00
Coffee Available

17:00—19:00
Cell Death Signaling II
Registered attendees can view abstracts starting on 09/28/2014

* Herbert W. Virgin, Washington University School of Medicine, USA

Beth Levine, University of Texas Southwestern Medical Center, USA
Autophagic Cell Death

Peter Vandenabeele, VIB, Ghent University, Belgium
Necroptosis versus Apoptosis

Francis Ka-Ming Chan, University of Massachusetts Medical School, USA
Playing with Fire: Necroptosis-Dependent and Independent Roles of RIPK3 in Inflammation

Silvia Alvarez-Diaz, Walter and Eliza Hall Institute, Australia
Short Talk: MLKL Plays a Critical Role Inducing Necroptosis within a Physiological Context

19:00—20:00
Social Hour with Lite Bites

19:30—22:00
Poster Session 1


THURSDAY, OCTOBER 30

07:30—08:30
Breakfast

08:30—11:45
Cell Death and Cancer I
Registered attendees can view abstracts starting on 09/28/2014

* Karen H. Vousden, Beatson Institute for Cancer Research, UK

Andreas E. Strasser, Walter and Eliza Hall Institute of Medical Research, Australia
How Does p53 Prevent Cancer?

David W. Andrews, University of Toronto, Canada
Regulation of Mitochondrial Membrane Permeabilization by Bcl-2 Family Proteins

Axel Witt, University Hospital Cologne, Germany
Short Talk: IAP Antagonization Induces Inflammatory Destruction of Vasculature Endothelium and Inhibits Tumor Growth

Gerry Melino, University of Rome ‘Tor Vergata’, Italy
Control of Cell Fate by miRNA

Ruslan M. Medzhitov, HHMI/Yale University School of Medicine, USA
Cellular Cooperation in Normal Tissues and Tumors

Stephen W. Fesik, Vanderbilt University School of Medicine, USA
Short Talk: Mcl-1 Inhibitors for the Treatment of TNBC and Other Cancers

09:50—10:10
Coffee Break

11:45—13:00
Poster Setup

11:45—14:30
On Own for Lunch

13:00—22:00
Poster Viewing

14:30—16:30
Workshop 2: Host Defense

* Petr Broz, Biozentrum, University of Basel, Switzerland

* Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital, USA

Goutam Gupta, Los Alamos National Laboratory, USA
Preventing Host Cell Death by Engineering of Novel Innate Immune Defense

Luciana Paroneto Medina, Institute of Biomedical Sciences, University of São Paulo, Brazil
PGE2 as a Regulator of Experimental Autoimmune Encephalomyelitis (EAE)

Maria Andree, University of Cologne, Germany
BID-Dependent Release of Mitochondrial SMAC Dampens XIAP-Mediated Immunity Against Shigella

Dmitry M. Shayakhmetov, Emory University, USA
The Identification of the Novel Physiologically-Regulated Necrotic Cell Death Pathway Mediated by the Interferon-Regulatory Factor 3 (IRF3)

Eugenio D. Hottz, Oswaldo Cruz Foundation, Brazil
Activation of Inflammasome and Cell Death Pathways in Platelets Modulate Inflammatory Responses in Dengue

Bernardo S. Franklin, University of Bonn, Germany
The Extracellular Functions of the Inflammasomes

Jennifer Martinez, St. Jude Children's Research Hospital, USA
LC3-Associated Phagocytosis as a Critical Regulator of Inflammation

16:30—17:00
Coffee Available

17:00—19:00
Cell Death and Cancer II
Registered attendees can view abstracts starting on 09/28/2014

* Simone Fulda, University Hospital Frankfurt, Germany

Gerard I. Evan, University of Cambridge, UK
Killing Cancers without Killing Normal Tissues

Karen H. Vousden, Beatson Institute for Cancer Research, UK
Metabolic Control of Cancer Cell Fate Decisions

Anthony G. Letai, Dana-Farber Cancer Institute, USA
Kicking Cancer Right in the Mitochondria

Andreas Bergmann, University of Massachusetts Medical School, USA
Short Talk: Autophagy Regulates Tissue Overgrowth in a Context-Dependent Manner

19:00—20:00
Social Hour with Lite Bites

19:30—22:00
Poster Session 2


FRIDAY, OCTOBER 31

07:30—08:30
Breakfast

08:30—11:45
Cell Death and Host Defense I
Registered attendees can view abstracts starting on 09/28/2014

* Ruslan M. Medzhitov, HHMI/Yale University School of Medicine, USA

Herbert W. Virgin, Washington University School of Medicine, USA
Role of Autophagy Genes in Inflammation and Immunity through Effects on Cell Survival and Basal Innate Immune Tone

Petr Broz, Biozentrum, University of Basel, Switzerland
Caspase-11 Activation Requires Lysis of Pathogen-Containing Vacuoles by IFN-Induced GTPases

Domagoj Vucic, Genentech, Inc., USA
Short Talk: IAP Proteins Regulate the Formation of Necrosome and Inflammasome Complexes

Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital, USA
Inflammasome Control of Disease

Karina R. Bortoluci, Federal University of São Paulo, Brazil
Lysosomal Pathway Induced by Cytosolic Flagellin in Cell Death and Immunity

Igor E. Brodsky, University of Pennsylvania, USA
Short Talk: RIPK1 and Caspase-8 Catalytic Activity Mediate Caspase-1 Activation in Response to Pathogen Blockade of Innate Immune Signaling

09:50—10:10
Coffee Break

11:45—13:00
Poster Setup

11:45—17:00
On Own for Lunch

13:00—22:00
Poster Viewing

16:30—17:00
Coffee Available

17:00—19:00
Cell Death and Host Defense II
Registered attendees can view abstracts starting on 09/28/2014

* Eric H. Baehrecke, University of Massachusetts Medical School, USA

Janelle S. Ayres, The Salk Institute, USA
Microbiota Control of Infection and Inflammation Induced Pathology

Gustavo P. Amarante-Mendes, Universidade de São Paulo, Brazil
Short Talk: Novel Role for Galectin-1 in CTL Killing

Seamus J. Martin, Trinity College Dublin, Ireland
Cell Death and Inflammation: Revisiting the Danger Model

Avi Ashkenazi, Genentech, Inc., USA
Opposing UPR Signals Converge on DR5 to Control Apoptosis

19:00—20:00
Social Hour with Lite Bites

19:30—22:00
Poster Session 3


SATURDAY, NOVEMBER 1

07:30—08:30
Breakfast

08:30—11:45
Consequences of Cell Death
Registered attendees can view abstracts starting on 09/28/2014

* Peter Vandenabeele, VIB, Ghent University, Belgium

Shigekazu Nagata, Kyoto University, Japan
Exposure of Phosphatidylserine during Apoptosis

Kim Newton, Genentech, USA
Necroptosis Signaling and Inflammation

Andrew Oberst, University of Washington, USA
Short Talk: Inflammatory and Immune Responses to Apoptosis and Necroptosis

Will Wood, University of Bristol, UK
Signal Prioritization: Recognizing Death and Damage in vivo

Eric H. Baehrecke, University of Massachusetts Medical School, USA
Inflammatory Signaling, Autophagy and Dying Cell Clearance

Linda Julian, Beatson Institute for Cancer Research, UK
Short Talk: Apoptotic Blebbing in Tissue Homeostasis and Cancer

09:50—10:10
Coffee Break

11:45—17:00
On Own for Lunch

16:30—17:00
Coffee Available

17:00—18:15
Cell Death Therapies
Registered attendees can view abstracts starting on 09/28/2014

* Kim Newton, Genentech, USA

Simone Fulda, University Hospital Frankfurt, Germany
Novel Opportunities to Target IAP Proteins for Cancer Therapy

David Ching Huang, Walter and Eliza Hall Institute of Medical Research, Australia
Therapeutically Targeting the Bcl-2-Regulated Cell Survival Pathway

18:15—19:15
Closing Keynote Address
Registered attendees can view abstracts starting on 09/28/2014

* Gustavo P. Amarante-Mendes, Universidade de São Paulo, Brazil

Scott W. Lowe, HHMI/Memorial Sloan-Kettering Cancer Center, USA
Tumor Suppressor and Tumor Maintenance Genes

19:15—20:15
Social Hour with Lite Bites

20:00—23:00
Entertainment


SUNDAY, NOVEMBER 2

 
Departure


*Session Chair †Speaker invited, not yet responded.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

AbbVie Inc. Genentech, Inc.
H3 Biomedicine Inc. National Council for Scientific and Technological Development (CNPq) - Brazil
São Paulo Research Foundation (FAPESP) - Brazil TESARO, Inc.

We gratefully acknowledge additional support for this conference from:

Cell Signaling Technology, Inc.

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Genentech, Inc.


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Amanda Deem, Assistant Director of Development, Email: AmandaD@keystonesymposia.org,
Phone:+1 970-262-2668

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676