Beaver Run Resort Floorplan

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This meeting took place in 2016



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Molecular and Cellular Basis of Growth and Regeneration (A3)


Organizer(s) Alejandro Sánchez Alvarado, Duojia D.J. Pan and Valentina Greco
January 10—14, 2016
Beaver Run Resort • Breckenridge, Colorado USA
Discounted Abstract Deadline: Sep 22, 2015
Abstract Deadline: Oct 21, 2015
Scholarship Deadline: Sep 22, 2015
Discounted Registration Deadline: Nov 10, 2015

Sponsored by Cell Research

Summary of Meeting:
The regulation of scale and proportion is a fundamental attribute of life. Yet, the molecular, cellular and systems-level mechanisms regulating these processes remain largely unknown. How is organ size achieved in animals during normal development, and how is it reconstituted in animals capable of regenerating organs and body parts lost to injury? Are the mechanisms regulating size and allometry evolutionarily conserved? In recent years, discoveries in the fields of signaling, physiology, developmental biology and regeneration using a growing and diverse collection of model organisms have begun to shed mechanistic insight into these problems. This meeting aims to delineate the molecular and cellular basis of growth and regeneration by highlighting, comparing and contrasting the differences and similarities in scale and proportion mechanisms and stem cell management among diverse animal species. How these biological findings may inform regenerative medicine and stem cell biology and therapeutics will be considered and discussed.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Sunday, January 10 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, January 14 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, January 15 in order to fully experience the meeting.

SUNDAY, JANUARY 10

16:00—20:00
Arrival and Registration

Foyer
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Foyer

MONDAY, JANUARY 11

07:00—08:00
Breakfast

Summit Gallery
08:00—09:00
Welcome and Keynote Address
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Peaks 4-5
* Alejandro Sánchez Alvarado, Stowers Institute for Medical Research/HHMI, USA

Hopi E. Hoekstra, HHMI/Harvard University, USA
How the Mouse Got Its Stripes

09:00—11:30
Patterning, Growth and Regeneration
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Peaks 4-5
* Tatjana Piotrowski, Stowers Institute for Medical Research, USA

Norbert Perrimon, Harvard Medical School, USA
Signaling Mechanisms Involved in Drosophila Gut Regeneration

Dunja Knapp, CRTD, Germany
Molecular Mechanisms Integrating Positional Information with Injury Induced Growth during Limb Regeneration

Valentina Greco, Yale School of Medicine, USA
Balancing Tissue Homeostasis with Repair by Two Photon Imaging in Living Mice

Kenneth D. Birnbaum, New York University, USA
Short Talk: Reliving the Past: Regeneration Closely Recapitulates Embryogenesis in the Plant Root

Chloe E. Emerson, Bermuda Institute of Ocean Sciences, Bermuda
Short Talk: Sea Urchins as a Model for Tissue Regeneration: Role of Notch Signaling and Presence of Stem Cell Markers

09:40—10:00
Coffee Break

Foyer
11:30—13:00
Poster Setup

Peaks 1-3
13:00—22:00
Poster Viewing

Peaks 1-3
11:30—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Foyer
17:00—19:00
Size Regulation and Signaling Pathways
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Peaks 4-5
* Vicki Pero Losick, MDI Biological Laboratory, USA

Duojia D.J. Pan, HHMI/Johns Hopkins University School of Medicine, USA
The Hippo Pathway and Organ Size Regulation

Laura Johnston, Columbia University, USA
Sensing and Responding to Cell Fitness Differences during Tissue Growth

Tatjana Piotrowski, Stowers Institute for Medical Research, USA
Signaling Interactions that Control Progenitor Number, Maintenance, and Differentiation in Sensory Hair Cell Regeneration

Eric M. Hill, Northwestern University, USA
Short Talk: Wnt/Notum Spatial Feedback Inhibition Controls Neoblast Differentiation to Regulate Reversible Growth of the Planarian Brain

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Peaks 1-3
19:30—22:00
Poster Session 1

Peaks 1-3

TUESDAY, JANUARY 12

07:00—08:00
Breakfast

Summit Gallery
08:00—11:15
Organ and Systemic Regulation of Scale and Proportion
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Peaks 4-5
* Eric M. Hill, Northwestern University, USA

Nadia A. Rosenthal, The Jackson Laboratory, USA
Immune Regulation of Regeneration

Richard Schneider, University of California, San Francisco, USA
Regulation of Jaw Size during Development and Evolution

David D. Moore, Baylor College of Medicine, USA
Making Hepatocytes without Stem Cells

Arkhat Abzhanov, Imperial College London, UK
Evolution of the Animal Face: From Principles to Mechanisms

Joseph T. Rodgers, University of Southern California Keck School of Medicine, USA
Short Talk: Systemic Regulation of Quiescent Stem Cell Function and Regenerative Potential

Vicki Pero Losick, MDI Biological Laboratory, USA
Short Talk: Going BIG for Wound Repair

09:20—09:40
Coffee Break

Foyer
11:15—13:00
Poster Setup

Peaks 1-3
13:00—22:00
Poster Viewing

Peaks 1-3
11:15—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Foyer
17:00—19:15
Epigenetics in Growth and Regeneration
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Peaks 4-5
* Jochen C. Rink, Max Planck Institute of Molecular Cell Biology and Genetics, Germany

Julie C. Baker, Stanford University, USA
Genomics of Tissue Development

Antonio J. Giraldez, Yale University School of Medicine, USA
The Hidden Code Behind the Genetic Code: Codon Optimality Regulates mRNA Translation and Stability during the Maternal to Zygotic Transition

Elena Ezhkova, Icahn School of Medicine at Mount Sinai, USA
Epigenetic Regulation of Skin Stem Cell Control and Differentiation

Charles Sagerström, University of Massachusetts Medical School, USA
Short Talk: Prep/Meis and Pbx Cofactors Poise Promoters for Activation by Hox Proteins

Elizabeth M. Duncan, Stowers Institute for Medical Research, USA
Short Talk: Histone H3 Lysine 4 Methyltransferases Set1 and MLL1/2 Target Distinct Genomic Loci in vivo

19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Peaks 1-3
19:30—22:00
Poster Session 2

Peaks 1-3

WEDNESDAY, JANUARY 13

07:00—08:00
Breakfast

Summit Gallery
08:00—11:15
Genetics of Growth and Regeneration
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Peaks 4-5
* Elena Ezhkova, Icahn School of Medicine at Mount Sinai, USA

Bruce A. Edgar, German Cancer Research Center, Germany
Regeneration and Tumorigenesis in the Drosophila Intestinal Epithelium

Mary Baylies, Memorial Sloan Kettering Cancer Center, USA
Regulation of Muscle Cell Size and Organization

Matthew Charles Gibson, Stowers Institute for Medical Research, USA
Coordinating Mitosis and Morphogenesis during Early Embryogenesis of the Sea Anemone, Nematostella vectensis

Kenneth D. Poss, Duke University Medical Center, USA
Regeneration in Zebrafish

Andreas Bergmann, University of Massachusetts Medical School, USA
Short Talk: Extracellular Reactive Oxygen Species Drive Apoptosis-induced Proliferation via Drosophila Macrophages

Pranidhi Sood, University of California, San Francisco, USA
Short Talk: Transcriptional Dynamics of Single-Cell Regeneration in the Ciliate Stentor coeruleus

09:20—09:40
Coffee Break

Foyer
11:15—13:00
Poster Setup

Peaks 1-3
13:00—22:00
Poster Viewing

Peaks 1-3
11:15—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Foyer
17:00—19:00
Genetics of Morphological Variation
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Peaks 4-5
* Jayaraj Rajagopal, Massachusetts General Hospital, USA

Elaine Ostrander, National Human Genome Research Institute, USA
Genomics of Growth in Canines

David M. Kingsley, Stanford University, USA
Fishing for the Secrets of Evolutionary Change in Vertebrates

Shishir K. Biswas, University of Kentucky, USA
Short Talk: Comparative RNA-seq between Acomys cahirinus (Regenerator) and Mus musculus (Non-Regenerator) Reveals Insights into Genetic Control of Mammalian Regeneration

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Peaks 1-3
19:30—22:00
Poster Session 3

Peaks 1-3

THURSDAY, JANUARY 14

07:00—08:00
Breakfast

Summit Gallery
08:00—11:00
Physical Forces, Growth and Scale
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Peaks 4-5
L. Mahadevan, Harvard University, USA
The Physical Bases for Morphogenesis

Marcos Gonzalez-Gaitan, University of Geneva, Switzerland
Biophysics of Tissue Growth and Morphogens

Yohanns Bellaïche, Institut Curie, France
Cell Division and Epithelial Tissue Morphogenesis

Aaron F. Mertz, Rockefeller University, USA
Short Talk: How is a Stratified Epithelium Built Mechanically in vivo?

Mei-I Chung, Duke University, USA
Short Talk: Rage (Receptor for Advanced Glycation End Products)-Directed Fluorescent Protein Provides a Tool for Studying Alveolar Type I Epithelial Cells

Jochen C. Rink, Max Planck Institute of Molecular Cell Biology and Genetics, Germany
Short Talk: Mechanisms of Growth and Patterning in Planarian Flatworms

09:20—09:40
Coffee Break

Foyer
11:00—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Foyer
17:00—18:45
Stem Cells, Self-Assembly, Tissue Growth and Regeneration
Meeting has ended...abstracts no longer viewable online. Purchase an Abstract Book from this meeting

Peaks 4-5
* Yohanns Bellaïche, Institut Curie, France

Jayaraj Rajagopal, Massachusetts General Hospital, USA
Stem Cells as Niches for their Own Progeny: New Modes of Stem Cell Regulation

Joachim Wittbrodt, Heidelberg University, Germany
The Memory of Retinal Stem Cells: How to Shape Form and Function

Alejandro Sánchez Alvarado, Stowers Institute for Medical Research/HHMI, USA
Stem Cell Population Dynamics, Tissue Homeostasis and Regeneration

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)

Peaks 4-5
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Peaks 1-3
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Peaks 1-3

FRIDAY, JANUARY 15

 
Departure


*Session Chair †Invited, not yet responded.



Keystone Symposia thanks our Sponsor for generously supporting this meeting:

Cell Research

We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge additional support for this conference from:

March of Dimes Foundation, Grant No. 4-FY15-442 The Company of Biologists

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Assistant Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676