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This meeting took place in 2016


Here are the related meetings in 2017:
Mononuclear Phagocytes in Health, Immune Defense and Disease (D3)

For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Myeloid Cells (D3)


Organizer(s) Arturo Zychlinsky, Judith E. Allen, Eicke Latz and Kate A. Fitzgerald
April 10—14, 2016
INEC-Ireland's National Events Centre • Killarney, Co. Kerry Ireland
Discounted Abstract Deadline: Dec 10, 2015
Abstract Deadline: Jan 11, 2016
Scholarship Deadline: Dec 10, 2015
Discounted Registration Deadline: Feb 10, 2016

Local Co-Organizer: Andrew G. Bowie of Trinity Biomedical Sciences Institute. Organized in Collaboration with Science Foundation Ireland. Sponsored by Biogen

Summary of Meeting:
Myeloid cells are essential in immunity: they control the interaction of the host with the environment and are indispensable in fighting infections and in the communication with other branches of the immune system. The introduction of new technology is revealing unprecedented levels of complexity in ontogeny, specialization, regulation and modulation of adaptive immunity by these cells. This Keystone Symposia meeting will cover topical questions in myeloid cell biology, including new concepts like the origin of myelocytes, trained immunity, and epigenetic and genetic regulation of their function. It will cover myeloid cells of both bone marrow and fetal origin with an emphasis on how macrophages interact with other myeloid cells including granulocytes. There will also be an emphasis on clinical approaches including medical intervention. New approaches to understand the diversity and specificity of myeloid responses will be also included. The symposium will include different fields central to contemporary immunology both at the genetic and cellular level, including the instruction of the adaptive immune response by innate immunity in health and disease. It should therefore be of interest to both basic and clinical scientists working in cell biology, immunology and infectious disease.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Sunday, April 10 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, April 14 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, April 15 in order to fully experience the meeting.

SUNDAY, APRIL 10

16:00—20:00
Arrival and Registration

Foyer
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Foyer

MONDAY, APRIL 11

07:30—08:30
Breakfast

Foyer
08:30—08:45
Welcoming Remarks

INEC Main Auditorium
* Judith E. Allen, University of Manchester, UK

08:45—09:45
Keynote Address
Meeting has ended...abstracts no longer viewable online.

INEC Main Auditorium
* Dana Philpott, University of Toronto, Canada

Douglas Golenbock, University of Massachusetts Medical School, USA
NLRP3 Inflammasome, Alzheimer's and Death: IL18 as an Antidote for IL1-Beta

09:45—12:30
Origins and Diversity
Meeting has ended...abstracts no longer viewable online.

INEC Main Auditorium
* Carla V. Rothlin, Yale University, USA

Filip K. Swirski, Massachusetts General Hospital, USA
Monocyte and Macrophage Heterogeneity

Martin Guilliams, Ghent University - VIB, Belgium
Yolk Sac Macrophages, Fetal Liver Monocytes and Adult Monocytes can all Efficiently Colonize an Empty Niche and Develop into Functional Tissue Resident Macrophages

Maria Rescigno, European Institute of Oncology, Italy
Dendritic Cells in the Gut

Steffen Jung, Weizmann Institute of Science, Israel
Development and Tissue Specialisation of Macrophages

10:20—10:40
Coffee Break

Foyer
12:30—17:00
On Own for Lunch

12:30—13:00
Poster Setup

Foyer
13:00—22:00
Poster Viewing

Foyer
16:30—17:00
Coffee Available

Foyer
17:00—19:15
Taming Inflammation
Meeting has ended...abstracts no longer viewable online.

INEC Main Auditorium
* Irina A. Udalova, University of Oxford, UK

Dana Philpott, University of Toronto, Canada
NLRs in Infection

Arturo Zychlinsky, Max Planck Institute for Infection Biology, Germany
Inflammatory Neutrophil Mechanisms

Kathryn J. Moore, New York University Medical Center, USA
MicroRNA Regulation of Macrophage Metabolism and Immune Response

Basak B. Cicek, University of Connecticut Health Center, USA
Short Talk: Discovery of a Novel Subset of Lung Resident Macrophages that Regulate Pathogen Clearance and Immune Homeostasis during Respiratory Infection

Julia Esser-von Bieren, Technical University and Helmholtz Centre Munich, Germany
Short Talk: Age-Dependent Regulation of Remodeling Factors Governs Myeloid-Epithelial Cell Crosstalk during Airway Inflammation

19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Foyer
19:30—22:00
Poster Session 1

Foyer

TUESDAY, APRIL 12

07:30—08:30
Breakfast

Foyer
08:30—11:45
Mechanisms of Differentiation and Activation
Meeting has ended...abstracts no longer viewable online.

INEC Main Auditorium
* Kathryn J. Moore, New York University Medical Center, USA

Sergio Grinstein, Hospital for Sick Children, Canada
Integrins Form an Expanding Diffusion Barrier that Enables Src-Family Kinase Activation during Phagocytosis.

Seamus J. Martin, Trinity College Dublin, Ireland
Neutrophil Granule Proteases Act as Global Regulators of Extended IL-1 Family Cytokine Activation States

Kate A. Fitzgerald, University of Massachusetts Medical School, USA
Regulation of Inflammation by Long Noncoding RNAs

Irina A. Udalova, University of Oxford, UK
IRF5 Controls Acute Inflammation: Cross-Talk of Myeloid Cells

Helen S. Goodridge, Cedars-Sinai Medical Center, USA
Short Talk: Independent Production of Distinct Monocyte Subsets by Granulocyte-Monocyte Progenitors (GMPs) and Monocyte-Dendritic Cell Progenitors (MDPs)

Philipp Henneke, University-Medical Center Freiburg, Germany
Short Talk: A Novel Macrophage Subset Instructs Immunity in Staphylococcal Skin Infection

09:50—10:10
Coffee Break

Foyer
11:45—17:00
On Own for Lunch

11:45—13:00
Poster Setup

Foyer
13:00—22:00
Poster Viewing

Foyer
16:30—17:00
Coffee Available

Foyer
17:00—19:15
Myeloid Cells in Disease Models I
Meeting has ended...abstracts no longer viewable online.

INEC Main Auditorium
* Nicola L. Harris, École Polytechnique Fédérale de Lausanne, Switzerland

Gretchen E. Diehl, Baylor College of Medicine, USA
Crosstalk between Intestinal Myeloid Cells and the Microbiota Limit Intestinal Inflammation

Judith E. Allen, University of Manchester, UK
Dynamics of Resident vs. Recruited Macrophages

Eicke Latz, University of Bonn, Germany
Inflammasome Activation in Disease

Florent Ginhoux, Singapore Immunology Network, Singapore
Short Talk: Dendritic Cell and Macrophage Ontogeny

Yonit Lavin, Mount Sinai School of Medicine, USA
Short Talk: Multi-Parameter Analysis of Myeloid Cells Allows for Identification of Distinct Populations in the Lung and Tumor of Non-Small Cell Lung Cancer Patients

19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Foyer
19:30—22:00
Poster Session 2

Foyer

WEDNESDAY, APRIL 13

07:30—08:30
Breakfast

Foyer
08:30—11:45
Myeloid Cells in Disease Models II
Meeting has ended...abstracts no longer viewable online.

INEC Main Auditorium
* Maria Rescigno, European Institute of Oncology, Italy

* Adam Lacy-Hulbert, Benaroya Research Institute, USA

Nicola L. Harris, École Polytechnique Fédérale de Lausanne, Switzerland
Macrophages in Infection and Repair

P'ng Loke, New York University School of Medicine, USA
Alternatively Activated M2 Macrophages in Helminth Infections

Felix Meissner, Max Planck Institute of Biochemistry, Germany
Quantitative Proteomics of Secreted Proteins Defines How Macrophages Regulate Inflammation

Carla V. Rothlin, Yale University, USA
TAM Receptors in Immunity

Christina Kassiteridi, Oxford University, UK
Short Talk: Myeloid Cell Regulation by CD200 Signalling in Atherosclerosis

Marlene Magalhaes Pinto, University of Edinburgh, Queen's Medical Research Institute, UK
Short Talk: IL-33 Controls the Establishment of Adipose Tissue Macrophage Subsets during Neo-Natal Development

09:50—10:10
Coffee Break

Foyer
11:45—17:00
On Own for Lunch

11:45—13:00
Poster Setup

Foyer
13:00—22:00
Poster Viewing

Foyer
16:30—17:00
Coffee Available

Foyer
17:00—19:15
Neutrophils
Meeting has ended...abstracts no longer viewable online.

INEC Main Auditorium
* Gretchen E. Diehl, Baylor College of Medicine, USA

Lani Wu, University of California, San Francisco, USA
Deciphering Neutrophil Chemotaxis

Christoph Klein, Ludwig-Maximilians-University Munich, Germany
Inborn Errors of Neutrophil Granulocytes

Eric Pearlman, University of California, Irvine, USA
NLRP3 Inflammasome Activation and P2X7R Induced IL-1 beta Secretion by Neutrophils

Regina Clemens, University of California, San Francisco, USA
Short Talk: STIM2-Mediated Store-Operated Calcium Entry Regulates Neutrophil Cytokine Production

Maria Casanova-Acebes, Mount Sinai School of Medicine, USA

19:15—20:15
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Foyer
19:30—22:00
Poster Session 3

Foyer

THURSDAY, APRIL 14

07:30—08:30
Breakfast

Foyer
08:30—11:45
Trained Immunity
Meeting has ended...abstracts no longer viewable online.

INEC Main Auditorium
* Maria Belvisi, Imperial College London, UK

Gioacchino Natoli, IEO, European Institute of Oncology, Italy
The Genomic Landscapes of Inflammation

Mihai G. Netea, Radboud University, Netherlands
Trained Immunity: A Memory for the Innate Immune Responses

Joachim L. Schultze, LIMES Institute, University of Bonn, Germany
The Multi-Dimensional Model of Macrophage Activation

Andrew G. Bowie, Trinity College Dublin, Ireland
PYHIN Proteins and Gene Regulation during Innate Immune Responses

Allan McI. Mowat, University of Glasgow, UK
Short Talk: TGFb Drives the Tissue Specific Differentiation of Monocytes into Homeostatic Intestinal Macrophages

Cristina Lopez-Rodriguez, Universitat Pompeu Fabra, Spain
Short Talk: Transcriptional Regulation of Inflammatory Gene Expression

09:50—10:10
Coffee Break

Foyer
11:45—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Foyer
17:00—18:45
Myeloid Cells in the Clinic
Meeting has ended...abstracts no longer viewable online.

INEC Main Auditorium
* Lani Wu, University of California, San Francisco, USA

Molly Ingersoll, Institut Pasteur, France
Hormone-mediated Differences in Innate Immune Responses Impact Bacterial Uptake and Clearance in Urinary Tract Infection

Matthew L. Albert, Genentech, Inc., USA
Systems Approach to Immune Monitoring and Immunotherapy

Maria Belvisi, Imperial College London, UK
Structural and Myeloid Cell Interactions in Lung Disease

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)

INEC Main Auditorium
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Foyer
19:45—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Foyer

FRIDAY, APRIL 15

 
Departure


*Session Chair †Invited, not yet responded.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Biogen Science Foundation Ireland

We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13AI122342-01

Funding for this conference was made possible [in part] by 1 R13 AI 122342 - 01 from the National Institute of Allergy and Infectious Diseases. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Assistant Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676