Keystone Resort Floorplan

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  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

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This meeting took place in 2016


Here are the related meetings in 2017:
Injury, Inflammation and Fibrosis (C8)

For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Fibrosis: From Basic Mechanisms to Targeted Therapies (Q3)


Organizer(s) Robert Lafyatis, Paolo G.V. Martini, Dean Sheppard and Lucie Peduto
February 7—11, 2016
Keystone Resort • Keystone, Colorado USA
Discounted Abstract Deadline: Oct 8, 2015
Abstract Deadline: Nov 10, 2015
Scholarship Deadline: Oct 8, 2015
Discounted Registration Deadline: Dec 8, 2015

Sponsored by Bayer HealthCare Pharmaceuticals, Biogen, Boehringer Ingelheim Pharmaceuticals, Inc., Bristol-Myers Squibb Company, Gilead Sciences, Inc., Intercept Pharmaceuticals, Inc., Merck & Co., Inc., Regeneron Pharmaceuticals, Inc., Shire Human Genetic Therapies and Theravance Biopharma


Summary of Meeting:
Fibrosis is the primary process of many diseases and the end-stage of many more, frequently leading to organ failure. However, the mechanisms leading to fibrosis have been poorly understood and available therapeutics targeting fibrosis limited. Increasingly, fibrosis is understood as a dynamic process that is orchestrated by the immune system, or activated by inflammation or cellular stress. Fibrosis of lung, kidney, skin, liver and muscle typically follow a variety of different stimuli. Advances in understanding Th2 cell responses, cell death, the inflammasome and ER and oxidative stresses provide new insights into such stimuli. Understanding the regulation of and interaction between profibrotic cytokines such as TGFb, IL-13, and CTGF are shedding additional light on fibrotic processes. Recent studies indicate that fibrosis is mediated by dedicated progenitor and resident cells within target tissues. Fibroblast and perivascular cell phenotype and differentiation are regulated not only by cytokines, but also by matrix composition and stiffness. Advances in the treatment of idiopathic pulmonary fibrosis and systemic sclerosis herald many new anti-fibrotic therapies that will soon enter clinical trials. Thus, mechanistic understandings will soon answer the long-standing clinical challenges of fibrotic and end-stage scarring diseases. This meeting aims to: 1) Present and discuss the most current and cutting-edge results regarding the mechanisms, signaling pathways, gene regulation, cells and tissues involved in fibrotic diseases and therapeutic approaches currently in development; 2) Include discussions and presentation of new ideas or paradigms that challenge existing models and expand on the knowledge of the current standard of care for fibrotic diseases; 3) Consider the future directions of the field, including the identification of the most pressing unanswered questions, the areas needing more focus, and those that would benefit from new approaches and methodologies developed and used in other related fields; 4) Stimulate collaborations in a setting conducive to focused, intense discussion among scientists with broad interests in fibrotic diseases and different targeted therapeutic approaches, including engagement with industrial partners interested in new targets in fibrotic disease; and 5) Provide a forum for trainees and new investigators to learn about current work in the field, to present their own work and to network with established investigators.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Sunday, February 7 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, February 11 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, February 12 in order to fully experience the meeting.

SUNDAY, FEBRUARY 7

16:00—20:00
Arrival and Registration

Longs Peak Foyer
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Longs Peak Foyer

MONDAY, FEBRUARY 8

07:00—08:00
Breakfast

Colorado Rockies Ballroom
08:00—09:30
Welcome and Keynote Session (Joint)
Meeting has ended...abstracts no longer viewable online.

Columbine Ballroom
* Robert Lafyatis, Boston University School of Medicine, USA

* Shannon J. Turley, Genentech, Inc., USA

Ronald N. Germain, NIAID, National Institutes of Health, USA
Imaging the Immune Cell–Stromal Interface in Lymphoid Tissues and Beyond

Fiona M. Watt, King's College London School of Medicine, UK
Contribution of Different Fibroblast Lineages to Skin Fibrosis

09:30—09:50
Coffee Break

Longs Peak Foyer
09:50—12:00
Stromal Cells in Inflammatory Disease (Joint)
Meeting has ended...abstracts no longer viewable online.

Columbine Ballroom
* Burkhard Ludewig, Kantonsspital St. Gallen, Switzerland
Fibroblastric Reticular Cells: Phenotype Follows Function

Timothy W. Schacker, University of Minnesota, USA
Lymphoid Tissue Fibrosis in HIV Infection

* Robert Lafyatis, Boston University School of Medicine, USA
Dermal Fibroblast Heterogeneity and Fibrosis in Systemic Sclerosis

Mo Ebrahimkhani, Arizona State University, USA
Short Talk: Engineering Human Organoids with Multiple Subsets of Stromal Cells

Jeffrey L. Browning, Boston University School of Medicine, USA
Short Talk: Fibroblasts in the Skin of Systemic Sclerosis Patients Share Characteristics with FRC in Lymphoid Organs

12:00—13:00
Poster Setup

Colorado Rockies Ballroom
13:00—22:00
Poster Viewing

Colorado Rockies Ballroom
12:00—17:00
On Own for Lunch


Following Session is for Stromal Cells in Immunity (Q4)

14:30—16:30
Workshop 1

Quandary Peak
* Jeffrey L. Browning, Boston University School of Medicine, USA

* Shannon J. Turley, Genentech, Inc., USA

Florent Carrette, Sanford Burnham Prebys Medical Discovery Institute, USA
CD44 is a New Immune Checkpoint that Promotes T Cell Exhaustion and Chronic Viral Infection through Expression on Fibroblastic Reticular Cells

Alice E. Denton, University of Cambridge, UK
Lymph Node Stromal Cells Derive from a Distinct Embryonic FAP+ Progenitor

Juan Dubrot, University of Geneva, Switzerland
MHCII-mediated Antigen-presentation by Lymph Node Stromal Cells in Peripheral Tolerance

Henrike Fleige, Hannover Medical School, Germany
The Role of Stromal Cells in Pathogen-induced BALT

Amanda Lund, Oregon Health & Science University, USA
Lymphatic Vessels are Required for Efficient Viral Clearance and Adaptive Immune Induction Following Epicutaneous Vaccinia Infection

Anna-Carin Andersson Lundell, Göteborg University, Sweden
Type I and II Interferons Induce BAFF Production from Human Decidual Stromal Cells

Helen M. McGettrick, University of Birmingham, UK
Identification of a Transitional Fibroblast Functional Phenotype in Early Rheumatoid Arthritis

Sarajo Mohanta, Ludwig-Maximilians University Munich, Germany
Chameleons in the Arterial Wall: Vascular Smooth Muscle Cells Transdifferentiate into Lymphoid Tissue Organizer Cells and Control Atherosclerosis Immunity

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Metabolic Stress and Fibrogenesis
Meeting has ended...abstracts no longer viewable online.

Grays/Longs Peak
* Mauricio Rojas, University of Pittsburgh, USA

* Maria Trojanowska, Boston University School of Medicine, USA

Timothy S. Blackwell, Vanderbilt University School of Medicine, USA
ER Stress in Lung Fibrosis

Ana L. Mora, University of Pittsburgh, USA
Fibrosis as a Disease of Aging and Mitochondrial Dysfunction

Philipp E. Scherer, University of Texas Southwestern Medical Center, USA
Fat Inflammation, Fibrosis and Remodeling

Kamran Atabai, University of California, San Francisco, USA
Short Talk: Functional Genomic Screen Identifies Novel Mediators of Collagen Uptake


Following Session is for Stromal Cells in Immunity (Q4)

17:00—19:15
Stromal Cell Function in the Initiation of Adaptive Immunity
Meeting has ended...abstracts no longer viewable online.

Quandary Peak
* Theresa T. Lu, Hospital for Special Surgery/Weill Cornell Medicine, USA
Regulating Lymph Node Vascular-Stromal Growth and Survival in Immunity

Antal Rot, University of York, UK
Expression and Function of Atypical Chemokine Receptor 4 in Salivary Glands

* Michael C. Carroll, Boston Children's Hospital, Harvard Medical School, USA
Lymph Node Fibroblast Reticular Cells in Regulation of Humoral Immunity

Mark C. Coles, University of York, UK
Short Talk: Role of microRNA Mediated Stromal Remodeling in Vaccine Efficacy

Sanjiv A. Luther, University of Lausanne, Switzerland
Short Talk: Identification of a New Fibroblast Subset Forming Plasma Cell Survival Niches in Activated Lymph Nodes

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Colorado Rockies Ballroom
19:30—22:00
Poster Session 1

Colorado Rockies Ballroom

TUESDAY, FEBRUARY 9

07:00—08:00
Breakfast

Colorado Rockies Ballroom
08:00—11:15
Extracellular Matrix Composition and Stiffness in Regulation of Cell Phenotype
Meeting has ended...abstracts no longer viewable online.

Grays/Longs Peak
* Dean Sheppard, University of California, San Francisco, USA

* Daniel Tschumperlin, Mayo Clinic, USA

Dennis E. Discher, University of Pennsylvania, USA
Fractal Heterogeneity of Model Scars Modulates Stiff-Niche Stem-Cell Responses via Nuclear Exit of a Mechanorepressor

Peter Bitterman, University of Minnesota, USA
IPF Extracellular Matrix Activates a Profibrotic Feedback Loop by Deregulating MicroRNA-29 at a Post-Processing Step

Andrew M. Tager, Massachusetts General Hospital, USA
Mitochondrial Priming by Matrix Stiffness Sensitizes Myofibroblasts to BH3 Mimetic-induced Apoptosis in Scleroderma Fibrosis

Victoria Smith, Gilead Sciences, USA
Allosteric Targeting of LOXL2

Brendon M. Baker, Boston University, USA
Short Talk: Cell-Mediated Fiber Recruitment Drives Extracellular Matrix Mechanosensing in Engineered Fibrillar Microenvironments

Tanya Kalin, Cincinnati Children's Hospital Medical Center, USA
Short Talk: FoxF1 Inhibits Pulmonary Fibrosis by Preventing Differentiation of Normal Lung Fibroblasts into Myofibroblasts


Following Session is for Stromal Cells in Immunity (Q4)

08:00—11:00
Stromal Cells in Lymphoid Development
Meeting has ended...abstracts no longer viewable online.

Quandary Peak
Andrea Brendolan, Ospedale San Raffaele srl, Italy
Transcriptional Control of Retinoic Acid Metabolism in Stromal Progenitors is Required to Ensure Spleen Development

Marc Bajénoff, Centre d'Immunologie Marseille-Luminy, France
Dynamics of Lymphoid Stromal Cells

Yang-Xin Fu, utsouthwestern medical center, USA
Targeting Tumor Stromal Microenvironment to Reprogram Tumor Immunity

* Jorge H. Caamano, College of Medicine - Univ. of Birmingham, UK
Development and function of Fat-Associated Lymphoid Clusters

Susan R. Schwab, New York University School of Medicine, USA
Short Talk: A Map of Sphingosine 1-Phosphate Distribution in the Spleen

09:20—09:40
Coffee Break

Longs Peak Foyer
11:15—13:00
Poster Setup

Colorado Rockies Ballroom
13:00—22:00
Poster Viewing

Colorado Rockies Ballroom
11:15—14:30
On Own for Lunch

14:30—16:30
Workshop: Assessing and Treating Human Fibrosis

Grays/Longs Peak
* Benjamin D. Humphreys, Washington University School of Medicine, USA

* David A. Schwartz, University of Colorado Denver, USA

Philip A. Waghorn, Martinos Biomedical Imaging Center, USA
Non-Invasive Imaging of Fibrogenesis using Magnetic Resonance Imaging (MRI)

Daryle DePianto, Genentech, USA
An in vitro Co-Culture System Recapitulating Epithelial-Mesenchymal Communication as a Tool for Investigating Mechanisms of IPF Pathogenesis

Alan Cyril Mullen, Massachusetts General Hospital / Harvard Medical School, USA
Long Noncoding RNAs Expressed in Human Hepatic Stellate Cells form Networks with Extracellular Matrix Proteins

Tatsuya Tsukui, University of Tokyo, Japan
Intratracheal Cell Transfer Demonstrates the Profibrotic Potential of Resident Fibroblasts in Pulmonary Fibrosis

Shuyu Ren, Biogen, USA
Multiple Domains of CTGF Amplify Pericyte Activation to Become Pathological Matrix Producing Cells

Claude Jourdan LeSaux, University of Texas Health Science Center, San Antonio, USA
Janus Kinase-1 Inhibitor Prevents Senescence in Mouse Lung Bleomycin Model Leading to Reduce Fibrosis

Resat Cinar, NIAAA, National Institutes of Health, USA
Improved Antifibrotic Efficacy and Safety of Hybrid Inhibitors of Peripheral CB1 Receptors and iNOS

Gerlinde Wernig, Institute for Regenerative Medicine and Stem Cell Research, USA
c-JUN is a Critical Mediator of Multi-Organ Fibrosis

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Adaptive Immunity, TH2 and IL-13 Fibrosis
Meeting has ended...abstracts no longer viewable online.

Grays/Longs Peak
* Lucie Peduto, Institut Pasteur, France

Cory Hogaboam, Cedars Sinai Medical Center, USA
Features of Immune Deregulation in IPF

* Thomas A. Wynn, NIAID, National Institutes of Health, USA

Padraic Fallon, Trinity College Dublin, Ireland
Innate Lymphoid Cells and Fibrosis

Joseph R. Arron, Genentech, Inc., USA
Targeting IL13 in Idiopathic Pulmonary Fibrosis

Richard Lee Gieseck III, NIAID, National Institutes of Health/University of Cambridge, USA
Short Talk: IL-13 Drives Distinct Cellular Pathways Directing Biliary Proliferation, Steatosis, and Fibrosis


Following Session is for Stromal Cells in Immunity (Q4)

17:00—19:00
Stromal Cell-Immune Cell Interactions in Non-Lymphoid Tissues
Meeting has ended...abstracts no longer viewable online.

Quandary Peak
* Gwendalyn J. Randolph, Washington University, USA
Collecting Vessel Permeability and Fibrosis: Regulation by CCR7 and IRF4-Dependent Dendritic Cells

Scott N. Mueller, University of Melbourne, Australia
Dynamic Responses of Lymphoid Stromal Cells to Infection

* Andrea Cerutti, Mount Sinai School of Medicine, USA
Role of Stromal Cells in Innate-Like Antibody Responses

Joana Campos, University of Birmingham, UK
Short Talk: ICOS-ICOSL Interaction Regulates Lymphotoxin-alpha Expression and Maturation of Lymphoid-like Stromal Cells during Inflammation

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Colorado Rockies Ballroom
19:30—22:00
Poster Session 2

Colorado Rockies Ballroom

WEDNESDAY, FEBRUARY 10

07:00—08:00
Breakfast

Colorado Rockies Ballroom
08:00—11:00
Perivascular Mesenchymal Cells and Vascular Niches: Versatile Cells in Health and Disease
Meeting has ended...abstracts no longer viewable online.

Grays/Longs Peak
* Theresa T. Lu, Hospital for Special Surgery/Weill Cornell Medicine, USA

* Jeremy S. Duffield, Biogen, USA

Lucie Peduto, Institut Pasteur, France
Perivascular Stromal Lineages in Fibrosis and Cancer

Benjamin D. Humphreys, Washington University School of Medicine, USA
Mesenchymal Stem Cells in Organ Fibrosis

Paul S. Frenette, Albert Einstein College of Medicine, USA
Mesenchymal Stromal Subsets and Vascular Niches in the Bone Marrow

Lorin Olson, Oklahoma Medical Research Foundation, USA
Short Talk: Adipose Tissue Fibrosis Driven by PDGFRalpha-Induced Cell Fate Switch in Fibro-Adipogenic Progenitor Cells

Irina Alexandra Leaf, Biogen, USA
Short Talk: Targeting MyD88-Dependent Signaling in Pericytes is Protective Against Tissue Injury and Fibrosis


Following Session is for Stromal Cells in Immunity (Q4)

08:00—11:15
Stromal Cells in Tumor-Promoting Inflammation and Anti-Tumor Immunity
Meeting has ended...abstracts no longer viewable online.

Quandary Peak
* Melody A. Swartz, University of Chicago, USA
Immune Regulation by Tumor Lymphangiogenesis

Shannon J. Turley, Genentech, Inc., USA
Stromal Cell Coordination of Leukocyte Function and Spatiality

Karin Tarte, Université de Rennes 1 - U917 Inserm, France
Lymphoid Stromal Cells in B-Cell Lymphoma

* Thomas Blankenstein, Max Delbruck Center for Molecular Medicine, Germany
Adoptive T Cell Therapy

Jenny Rudnick, University of California, San Francisco, USA
Short Talk: Autophagy Regulates the Tumor Promoting State of Mammary Fibroblasts

Jacqui Shields, University of Cambridge, UK
Short Talk: Tumor-Associated Stromal Cells Contribute to Immune Dysfunction Via Antigen-specific Deletion of CD8+ T Cells and Transcriptional Reprogramming

09:20—09:40
Coffee Break

Longs Peak Foyer
11:00—13:00
Poster Setup

Colorado Rockies Ballroom
13:00—22:00
Poster Viewing

Colorado Rockies Ballroom
11:00—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Fibrotic Muscle Disease
Meeting has ended...abstracts no longer viewable online.

Grays/Longs Peak
* Paolo G. V. Martini, Elpidera, A Moderna Venture, USA

* Elisabeth Barton, University of Florida, USA
Fibrosis in Muscular Dystrophy

Bruce M. Wentworth, Sarepta Therapeutics, USA
Phosphorodiamidate Morpholino Oligomers (PMOs) in Development for the Treatment of Duchenne Muscular Dystrophy (DMD)

Barbora Malecova, Sanford Burnham Prebys Medical Discovery Institute, USA
Short Talk: Single Cell Analysis Reveals Dynamic Transitions within Distinct Subpopulations of Fibro-Adipogenic Progenitors (FAPs) Implicated in Skeletal Muscle Regeneration or Fibrosis

Daniel Tschumperlin, Mayo Clinic, USA
Short Talk: RNAi Screening to Identify Genes Essential for Myofibroblast Activation


Following Session is for Stromal Cells in Immunity (Q4)

17:00—19:00
Stromal Cell Function in Chronic Inflammation
Meeting has ended...abstracts no longer viewable online.

Quandary Peak
* Michael B. Brenner, Harvard Medical School, USA
Targeting and Sub-setting Fibroblasts to Treat Tissue Degradation and Fibrosis

* Fiona M. Powrie, University of Oxford, UK
Innate Lymphoid Cells, Fibrosis and Inflammatory Bowel Disease

Christopher D. Buckley, University of Birmingham, UK
The Role of Stromal Cells in Chronic Inflammation

César Nombela-Arrieta, University Hospital Zurich, Switzerland
Short Talk: Chronic Viral Infections Induce Major Disruption of Bone Marrow Stromal Microarchitecture and Function

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Colorado Rockies Ballroom
19:30—22:00
Poster Session 3

Colorado Rockies Ballroom

THURSDAY, FEBRUARY 11

07:00—08:00
Breakfast

Colorado Rockies Ballroom
08:00—11:15
Immunity in Fibrotic Diseases
Meeting has ended...abstracts no longer viewable online.

Grays/Longs Peak
* Peter D. R. Higgins, University of Michigan, USA

Ariel E. Feldstein, University of California, San Diego, USA
Inflammasome in Liver Fibrosis

Florian Rieder, Lerner Research Institute, USA
Scarring in Inflammatory Bowel Disease

Jaap M. Van Laar, UMC Utrecht, Netherlands
Stem Cell Transplant, Blocking Fibrosis in Systemic Sclerosis by Resetting the Immune System

Richard Jack, Promedior, Inc., USA
PRM-151 (rhPTX-2) in Treating Fibrotic Diseases

Ivan G. Gomez, Biogen, USA
Short Talk: TNF Superfamily Receptor Fn14 Activates Myofibroblasts to Drive Progression of Fibrotic Disease of the Kidney

Boris Hinz, University of Toronto, Canada
Short Talk: Direct Adhesion of Macrophages Promotes Myofibroblast Differentiation by Establishing a Niche of Active TGF-Beta1


Following Session is for Stromal Cells in Immunity (Q4)

08:00—11:15
Stromal Cells in Immune Regulation, Tolerance and Autoimmunity
Meeting has ended...abstracts no longer viewable online.

Quandary Peak
Henrique Veiga-Fernandes, Instituto de Medicina Molecular, Portugal
Environmental Sensing by Blood Cells

* Jennifer L. Gommerman, University of Toronto, Canada
The Lymphotoxin Network and Stromal Cell Remodeling

Ross M. Kedl, University of Colorado Denver, USA
Antigen Archiving by Lymph Node Stroma: A Novel Function for the Lymphatic Endothelium

* Paul P. Tak, GlaxoSmithKline, UK
Towards Therapeutic Targeting of the Epigenome in Rheumatoid Arthritis

Kaisa Auvinen, University of Turku, Finland
Short Talk: The Endothelial Protein PLVAP in Lymphatics Controls the Entry of Antigens into the Lymph Nodes

Ivan Maillard, University of Michigan, USA
Short Talk: Stromal Cell Niches in Secondary Lymphoid Organs Drive T Cell Alloimmunity through Delta-Like1/4-Mediated Notch Signals

09:20—09:40
Coffee Break

Longs Peak Foyer
11:15—17:00
On Own for Lunch


Following Session is for Stromal Cells in Immunity (Q4)

14:30—16:30
Workshop 2

Quandary Peak
* Mark C. Coles, University of York, UK

* Sanjiv A. Luther, University of Lausanne, Switzerland

Chris G. Mueller, University of Strasbourg, France
Distinct and Overlapping Roles of RANKL and Lymphotoxin in the Regulation of CD169+ Lymph Node Macrophages

Rafael de Queiroz Prado, National Institutes of Health, USA
Distinct Role for IL-4/IL-13 Activated Monocytes/Macrophages during Type 2 Cytokine-driven Pulmonary Fibrosis

Lauren B. Rodda, University of California, San Francisco, USA
Phenotypic and Morphological Properties of Germinal Center Dark Zone Cxcl12-expressing Reticular Cells

Katarzyna Sitnik, Danish Technical University, Veterinary Institute, Denmark
Context Dependent Development of Lymphoid Stroma from BP3-PDPN+PDGFRalpha+/beta+CD34+ Adult Vascular Adventitial Cells

Nathalie Steinthal, University of Birmingham, UK
Cd248 Plays an Important Role in Controlling the Differentiation of Mesenchymal Stem Cells to Adult Lymphoid Stromal Cells

Seddon Thomas, NIEHS, National Institutes of Health, USA
Dendritic and Epithelial Cell Crosstalk in the Lung Orchestrates Immune Responses to Inhaled Allergens

Carolyn A. Thomson, University of Glasgow, UK
Novel Insights into the Intestinal Stromal Cells Network, Revealed by Selective Expression of the Atypical Chemokine Receptor ACKR4

Alice Anna Tomei, Diabetes Research Institute, USA
CCL21 Expression in Beta Cells Induces Lymph Node Mimicry in the Pancreas and Prevents Autoimmune Diabetes

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—18:45
Emerging Antifibrotic Therapies
Meeting has ended...abstracts no longer viewable online.

Grays/Longs Peak
* Lori Morton, Regeneron Pharmaceuticals, Inc., USA

Dean Sheppard, University of California, San Francisco, USA
Integrin-Mediated TGFbeta Activation

Luca Richeldi, University of Southampton, UK
Nintedanib

Jörg H.W. Distler, University of Erlangen-Nuremberg, Germany
Upstream and Downstream Targeting of TGFbeta Signaling in Fibrosis


Following Session is for Stromal Cells in Immunity (Q4)

17:00—19:00
Therapeutic Application and Modulation of Stromal Cell Function
Meeting has ended...abstracts no longer viewable online.

Quandary Peak
* Dhavalkumar D. Patel, Novartis Institutes for BioMedical Research, Switzerland
Stromal-Immune Cell Cross-Talk in Autoimmune Disease: Roles in Therapeutic Interventions

Biju Parekkadan, Massachusetts General Hospital, Harvard Medical School, USA
Stromal Cell Therapy

* Katarina Le Blanc, Karolinska Institute, Sweden
Bringing Mesenchymal Stem Cells into the Clinic

Nisarg Shah, Harvard University, USA
Short Talk: Recapitulating the Bone Marrow Stroma to Drive Immune Reconstitution

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)

Grays/Longs Peak

Following Session is for Stromal Cells in Immunity (Q4)

19:00—19:15
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)

Quandary Peak
Melody A. Swartz, University of Chicago, USA

Burkhard Ludewig, Kantonsspital St. Gallen, Switzerland

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Colorado Rockies Ballroom
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Colorado Rockies Ballroom

FRIDAY, FEBRUARY 12

 
Departure


*Session Chair †Invited, not yet responded.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Bayer HealthCare Pharmaceuticals Biogen
Boehringer Ingelheim Pharmaceuticals, Inc. Bristol-Myers Squibb Company
Gilead Sciences, Inc. Intercept Pharmaceuticals, Inc.
Merck & Co., Inc. Regeneron Pharmaceuticals, Inc.
Shire Human Genetic Therapies Theravance Biopharma

We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge additional support for this conference from:

Charles River Laboratories FibroGen Incorporated
Profil® Institute for Clinical Research, Inc. Promedior, Inc.

We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13HL131040-01

Funding for this conference was made possible (in part) by 1R13HL131040-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S.Government.


We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Genentech, Inc.


Gilead Sciences, Inc.


Inception Sciences


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Assistant Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676