Whistler Conference Centre Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

NOTES:
This meeting will be conducted in English.

All programs are subject to change. Check this site for updates.


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Twitter hashtag for this meeting: #KSimmreg

Immune Regulation in Autoimmunity and Cancer (D1)

Scientific Organizers: David A. Hafler, Vijay K. Kuchroo and Jane L. Grogan


March 26—30, 2017

Whistler Conference Centre, Whistler, British Columbia, Canada


Sponsored by Abide Therapeutics Inc., BioLegend, Inc., Genentech, Inc., Juno Therapeutics, MorphoSys AG, OncoMed Pharmaceuticals, Inc., Pfizer Inc. and Roche


Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.
BEWARE of booking lodging through companies unaffiliated with Keystone Symposia. Click here for more details.

Keystone Symposia is committed to maintaining a positive and respectful environment at its meetings. To this end, please review and comply with our policies.

DEADLINES:
Scholarship Deadline: Nov 29, 2016 [details]
Discounted Abstract Deadline: Nov 29, 2016 [details]
Abstract Deadline: Jan 10, 2017 [details]
Discounted Registration Deadline: Jan 25, 2017 [details]

Click here to view Cancellation Policy

Register Yourself Deadlines and Fees

Rates and Deadlines listed below are for the 2017-D1 "Immune Regulation in Autoimmunity and Cancer" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On November 29, 2016 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After November 29, 2016 until February 16, 2017 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
November 29, 2016 n/a
Discounted NON-STUDENT Registration
More details
Before and On January 25, 2017 845.00 USD
(includes 150.00 discount)
Regular NON-STUDENT Registration
More details
After January 25, 2017 995.00 USD
Discounted STUDENT Registration
More details
Before and On January 25, 2017 620.00 USD
(includes 150.00 discount)
Regular STUDENT Registration
More details
After January 25, 2017 770.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will accept no liability for money loss through bank charges, transfers or currency fluctuations.




Discounted Abstract Deadline: November 29, 2016


Abstract Submission Fee: 100.00 USD*
Submission by this date receives 50.00 USD discount.
*50.00 USD will be applied to Registration Fee when you register

Abstract Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadlines. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract early allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • accept your abstract online
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
(The Abstract Deadline: is January 10, 2017)

Global Health Travel Award Deadline:


Global Health Travel Award Details: You MUST complete your Global Health Travel Award appplication by the Global Health Travel Award Deadline and complete the other required steps (verify your contact information and submit a recommendation letter) to be considered for a travel award.


Click here to learn more about Global Health Travel Awards.

Scholarship Deadline: November 29, 2016


Scholarship Details: You MUST submit your abstract by the Scholarship Deadline and complete the other required steps (submit a scholarship application and submit a mentor letter) to be considered for a scholarship.

Click here to learn more about Scholarships.

Abstract Deadline: January 10, 2017


Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register

Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract by the Abstract Deadline allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.

(Discounted Abstract Deadline: is November 29, 2016)

Discounted Registration Deadline: January 25, 2017


Registration Fee: 845.00 USD* (includes 150.00 USD discount)
Student Registration Fee: 620.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

After the Discounted Registration Deadline:


Registration Fee: 995.00 USD*
Student Registration Fee: 770.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

Registration spaces are limited and may fill prior to discounted registration deadline.

Please be advised that a few meeting participants have received calls and emails from a number of different housing services - "Exhibitors Housing Services", "Global Housing", etc. THESE COMPANIES ARE NOT AFFILIATED WITH KEYSTONE SYMPOSIA and are not authorized by Keystone Symposia to contact you. These companies may tell you that the meeting is filling and seek to take your lodging reservation and obtain your credit card number. We highly recommend that you not make a reservation with these companies or any other housing service! These companies' representations to participants have been misleading. Please report to Keystone Symposia any calls or correspondence you might have received and book only through the lodging link on our website, an established travel agency, or directly with the hotel.
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Sunday, March 26 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, March 30 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, March 31 in order to fully experience the meeting.

SUNDAY, MARCH 26

16:00—20:00
Arrival and Registration

Grand Foyer
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Grand Foyer

MONDAY, MARCH 27

07:00—08:00
Breakfast

Sea to Sky C
08:00—09:00
Welcome and Keynote Address
Registered attendees can view abstracts starting on 02/26/2017

Sea to Sky B
* David A. Hafler, Yale University School of Medicine, USA

James P. Allison, University of Texas MD Anderson Cancer Center, USA
Cancer Immunotherapy

09:00—11:15
Tissue Micro-Immune Environments in Tumors and Autoimmune Tissue Inflammation
Registered attendees can view abstracts starting on 02/26/2017

Sea to Sky B
Padmanee Sharma, University of Texas MD Anderson Cancer Center, USA
From the Clinic to the Lab: Investigating Response and Resistance Mechanisms to Immune Checkpoint Therapy

Coffee Break

Jennifer L. Gommerman, University of Toronto, Canada
Compartmentalization of B Cells During CNS Inflammation

* Jane L. Grogan, Genentech, Inc., USA
Immunoregulatory Roles of TIGIT and PVR-nectin Family in Tumors

Abigail E. Overacre, University of Pittsburgh, USA
Short Talk: Interferon-gamma drives Treg Functional Instability thereby Promoting Anti-Tumor Immunity

11:15—17:00
On Own for Lunch

11:15—13:00
Poster Setup

Sea to Sky C
13:00—22:00
Poster Viewing

Sea to Sky C
14:30—16:30
Workshop 1: Effector T Cells

Sea to Sky B
* Thomas Korn, Technical University Munich, Germany

* Nina Bhardwaj, Icahn School of Medicine at Mount Sinai, USA

June-Yong Lee, New York University School of Medicine, USA
Systemic and Local Functions of Serum Amyloid A (SAA) in Th17 Cell Pathogenicity

Jinju Lee, Kyoto University Graduate School of Medicine, Japan
Regulation of Th17 Expansion by PGE2-EP2/EP4 Signaling and its Clinical Implication

Pradip Nair, Biocon Research Limited, India
T Cell Activation and Differentiation to Th17 Cells is Modulated by a CD6 Domain 1 Antibody Itolizumab

Patricia Castillo, University of Pittsburgh, USA
Disrupted Enteric Th17 Signaling Exacerbates Autoimmune Inflammation

Michael Waterfield, University of California, San Francisco, USA
Characterization of a Novel Epigenetic Regulator Required for Th17 Differentiation

Mark S. Sundrud, The Scripps Research Institute, USA
The Xenobiotic Transporter Mdr1 Permits T Cell Adaptation to Mucosa-Associated Bile Acids in the Ileum

Geoffrey Alexander Smith, University of California, San Francisco, USA
IL-2RB Receptor Levels Tune T-Cell IL-2 Responses by Altering Signaling Dynamics in Different T Cell Subsets

Peter A. Morawski, NIAID, National Institutes of Health, USA
Brain Infiltrating CD8+ T Cells in Lupus-Prone Mice

16:30—17:00
Coffee Available

Grand Foyer
17:00—19:00
Basic Mechanisms of T Cell Tolerance
Registered attendees can view abstracts starting on 02/26/2017

Sea to Sky B
* Jeffrey A. Bluestone, University of California, San Francisco, USA
Treg Biology and Treatment in Autoimmune Diseases and Cancer

David A. Hafler, Yale University School of Medicine, USA
IFNgamma Identifies Dysfunctional Regulatory T Cells in Autoimmunity and Cancer

Alexander Y. Rudensky, HHMI/Memorial Sloan Kettering Cancer Center, USA
Regulatory T Cells in Cancer

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Sea to Sky C
19:30—22:00
Poster Session 1

Sea to Sky C

TUESDAY, MARCH 28

07:00—08:00
Breakfast

Sea to Sky C
08:00—11:00
Metabolic Regulation of T Cell Function in Cancer and Autoimmunity
Registered attendees can view abstracts starting on 02/26/2017

Sea to Sky B
* Erika L. Pearce, Max Planck Institute of Immunobiology and Epigenetics, Germany
How Metabolism Influences CD8 Cells in Cancer

Douglas R. Green, St. Jude Children's Research Hospital, USA
Metabolic Pathways that Regulate Effector and Regulatory T Cell Responses

Coffee Break

Jens Titze, Vanderbilt University, USA
Rethinking Sodium Metabolism

Tomokazu Sumida, Yale School of Medicine, USA
Short Talk: Beta-catenin Links High Salt and Proinflammatory Signature in Treg

Seungho Lee, Yonsei University, South Korea
Short Talk: Exploration of Tumor Microenvironment and Metabolism using Tumor Infiltrating Lymphocytes and FDG-PET CT

11:00—17:00
On Own for Lunch

11:00—13:00
Poster Setup

Sea to Sky C
13:00—22:00
Poster Viewing

Sea to Sky C
14:30—16:30
Workshop 2: Tregs in Autoimmunity and Cancer

Sea to Sky B
* Alexander Y. Rudensky, HHMI/Memorial Sloan Kettering Cancer Center, USA

* Ana Carrizosa Anderson, Harvard Medical School, USA

Liliana Elisa Lucca†, Yale University, USA
PD-1 Marks Dysfunctional Regulatory T Cells in Malignant Gliomas

Maran L. Sprouse, Baylor College of Medicine, USA
High CD5 Expression is a Marker of Functional Regulatory T Cells in Autoimmunity

Catherine Konopacki, Memorial Sloan Kettering Cancer Center, USA
Foxp1 Is a Foxp3 Binding Partner that Contributes to Regulatory T Cell Stability and Function

Allison L. Bayer, University of Miami School of Medicine, USA
Immunomodulation Requirements for Treg Immunotherapy for Autoimmune Diabetes

Danbee Ha, Osaka University, Japan
ADCC-Mediated in vitro Depletion of Human Treg Cells by Anti-CTLA-4 mAb Enhances CD8+ T Cell Responses against Self/Tumor Antigens

David Bauche, Merck, USA
Foxp3+ Regulatory T Cells Prevent from ILC3-Driven Colitis

Wenxian Fu, University of California, San Diego, USA
A Tissue-Resident Macrophage Specific Coinhibitory Molecule Promotes Regulatory T Cell Differentiation and Stability

Dana Catherine Gilmore, University of Chicago, USA
Identification of Natural Peptide Epitopes Recognized by Regulatory T Cells

16:30—17:00
Coffee Available

Grand Foyer
17:00—19:00
Effector T Cell Dysfunction: Surface Receptors in Autoimmunity vs. Cancer
Registered attendees can view abstracts starting on 02/26/2017

Sea to Sky B
* Arlene H. Sharpe, Harvard Medical School, USA
Role of Coinhibitory Receptors in Controlling Effector T Cells

E. John Wherry, University of Pennsylvania, USA
Molecular Basis of T Cell Exhaustion: Insights for Immunotherapy

Ana Carrizosa Anderson, Harvard Medical School, USA
T Cell Dysfunction: From Co-Inhibitory Receptors to Molecular Programs

Christopher E. Rudd, University of Montreal, Canada
Short Talk: A Next Generation Approach using Small Molecules to Inhibit PD-1 Transcription Is as Effective as Anti-PD-1/PL1 Biologics in Immunotherapy

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Sea to Sky C
19:30—22:00
Poster Session 2

Sea to Sky C

WEDNESDAY, MARCH 29

07:00—08:00
Breakfast

Sea to Sky C
08:00—11:00
Innate Regulation of Autoimmunity and Cancer
Registered attendees can view abstracts starting on 02/26/2017

Sea to Sky B
Nina Bhardwaj, Icahn School of Medicine at Mount Sinai, USA
Role of Dendritic Cells and NK Cells in Mediating Anti-Tumor Responses

Thomas Korn, Technical University Munich, Germany
Trans-presentation of IL-6 by Dendritic Cells - A Novel Mode of IL-6 Signaling – Is Required for the Priming of Pathogenic TH17 Cells in vivo

Coffee Break

* Carla V. Rothlin, Yale University, USA
Innate Immune Checkpoints in Anti-Tumor Immunity

Mark J. Smyth, QIMR Berghofer Medical Research Institute, Australia
Barriers to NK Cell Control of Cancer

Keiji Hirota, Institute for Frontier Life and Medical Sciences, Kyoto University, Japan
Short Talk: An Inflammatory Cellular Network of Autoimmune Th17 Cells, GM-CSF-Producing ILCs and Synoviocytes in the Development of Autoimmune Arthritis

11:00—17:00
On Own for Lunch

11:00—13:00
Poster Setup

Sea to Sky C
13:00—22:00
Poster Viewing

Sea to Sky C
16:30—17:00
Coffee Available

Grand Foyer
17:00—19:00
B Cell Regulation of Autoimmunity
Registered attendees can view abstracts starting on 02/26/2017

Sea to Sky B
* Antonio Lanzavecchia, Institute for Research in Biomedicine, Switzerland
Mechanisms of Antibody Diversification

Kenneth Smith, University of Cambridge, UK
Predicting and Explaining the Future: A New Biology of Clinical Outcome in Autoimmunity?

Alicia Gonzalez-Martin, The Scripps Research Institute, USA
Short Talk: MicroRNA Control of B Cell Tolerance and Autoimmunity

Bonnie Huang, NHGRI, National Institutes of Health, USA
Short Talk: Dissecting T Follicular Helper Cell Development in vivo using CRISPR

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Sea to Sky C
19:30—22:00
Poster Session 3

Sea to Sky C

THURSDAY, MARCH 30

07:00—08:00
Breakfast

Sea to Sky C
08:00—11:15
Ten Years of Discovery of Th17 Cell: From Bench to Bedside
Registered attendees can view abstracts starting on 02/26/2017

Sea to Sky B
* Vijay K. Kuchroo, Brigham and Women's Hospital, Harvard Medical School, USA
Transcriptional Networks in Development of Th17 Cells

Dan R. Littman, HHMI, New York University School of Medicine, USA
Th17 Cells in the Gut Homoeostasis

Coffee Break

Federica Sallusto, University of Italian Switzerland, Switzerland
Autoreactive T Cells in Narcoleptic Patients

Daniel J. Cua, Merck Research Laboratories, USA
The IL-23-Th17 Immune Axis: From Mechanisms to Therapeutic Testing

Dhavalkumar D. Patel, Novartis Institutes for BioMedical Research, Switzerland
Therapeutic Targeting of Th17 Cells in Autoimmune Diseases

11:15—17:00
On Own for Lunch

14:30—16:30
Workshop 3: T Cell Tolerance, Exhaustion and Dysfunction in Autoimmunity and Cancer

Sea to Sky B
* Kenneth Smith, University of Cambridge, UK

Rachel S. Friedman†, National Jewish Health and University of Colorado, Denver, USA
MerTK Mediates T Cell Tolerance in the Pancreatic Islets during Type 1 Diabetes

Yemsratch T. Akalu, Yale University, USA
An eMERging Target in Cancer Immunotherapy

Rachael Bashford-Rogers†, University of Cambridge, UK
Using High-Throughput Sequencing to Reveal Insights into the Relationship between B-Cell Repertoire, Phenotype and Function in Health, Cancer and Autoimmune Disease

David M. Sansom, University College London Medical School, UK
CTLA-4 Mutations from Patients with Immune Dysregulation Syndromes Inform our Understanding of CTLA-4 Function

Jenny Cosby†, Emory University, USA
MOG-Specific Tolerance Mechanisms Limit Autoimmune Demyelinating Disease following Bacterial Delivery of MOG Epitope

John R. Sedy†, Sanford Burnham Prebys Medical Discovery Institute, USA
Cancer Mutations Targeting TNFRSF14 alter Microenvironment Checkpoint Interactions to Limit Tumor Clearance by Cytotoxic Cells

Greg M. Delgoffe, University of Pittsburgh, USA
Defects in Mitochondrial Biogenesis and Oxidative Function Underlie Tumor-Infiltrating T Dysfunction

16:30—17:00
Coffee Available

Grand Foyer
17:00—18:45
Systems Biology Approaches to Understanding Tolerance in Cancer and Autoimmunity
Registered attendees can view abstracts starting on 02/26/2017

Sea to Sky B
* Frank Oliver Nestle, King's College London, UK
Deciphering the Rules of Engagement of Tissue Immunity

Alex Marson, University of California, San Francisco, USA
Engineering Human T Cell Circuitry

Meromit Singer, Broad Institute, USA
Short Talk: Identification and Validation of a Gene Module Specific for T Cell Dysfunction in Tumor via Population and Single-Cell Transcriptomics

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 02/26/2017

Sea to Sky B
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Sea to Sky C
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Sea to Sky C

FRIDAY, MARCH 31

 
Departure


*Session Chair †Invited, not yet responded.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Abide Therapeutics Inc. BioLegend, Inc.
Genentech, Inc. Juno Therapeutics
MorphoSys AG OncoMed Pharmaceuticals, Inc.
Pfizer Inc. Roche

We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge additional support for this conference from:

CEDARLANE

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Genentech, Inc.


Novartis Institutes for BioMedical Research


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Assistant Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676