Speke Resort & Conference Centre Floorplan

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This meeting took place in 2018



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Leveraging Genomic Diversity to Promote Animal and Human Health (S5)


Organizer(s) Michèle Ramsay, Han Brunner and Appolinaire Djikeng
November 25—29, 2018
Speke Resort & Conference Centre • Kampala, Uganda
Discounted Abstract Deadline: Aug 8, 2018
Abstract Deadline: Aug 23, 2018
Scholarship Deadline: Aug 8, 2018
Discounted Registration Deadline: Oct 6, 2018

Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation

Summary of Meeting:
Genomic variation is a driving force of animal and human health, and susceptibility to disease. Yet our knowledge rarely spans human ethnic genomic diversity and genomic variation between animal breeds, limiting their translational impact. This symposium aims to: 1) Highlight translational genomics in humans and animals (clinical medicine and animal breeding for health and productivity; 2) Explore synergies and cross-disciplinary learning; 3) Explore opportunities to leverage genomic diversity to push the current boundaries to translation; and 4) Address translation and affordability in low- and middle-income settings. Large-scale genomics initiatives like Genome England, the US Precision Medicine initiative, and the Human Heredity and Health in African Consortium are providing extraordinarily large data sets to explore useful genotype-phenotype connections. Equivalent initiatives for animal data are starting. This meeting will explore the translation of genomic research in animals and humans, high and low-resourced environments, ethnic diversity, and cultural context. Identifying common strands in animal and human health opens up opportunities for repurposing of ideas and applications, and for finding innovative solutions for translational genomics through cross-boundary communities of practice.

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No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Sunday, November 25 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, November 29 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, November 30 in order to fully experience the meeting.

SUNDAY, NOVEMBER 25

16:00—20:00
Arrival and Registration

Victoria Ballroom Foyer
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Majestic Hall

MONDAY, NOVEMBER 26

09:00—10:30
Welcome and Keynote Address
Meeting has ended...abstracts no longer viewable online.

Victoria Ballroom
* Michèle Ramsay, University of Witwatersrand, South Africa

Evan E. Eichler, HHMI/University of Washington, USA
Relevance of Primate Evolution to Human and Animal Diversity

Coffee Break

11:00—12:00
Genomic Diversity in Health
Meeting has ended...abstracts no longer viewable online.

Victoria Ballroom
* Han G. Brunner, Radboud Maastricht University Medical Center, Netherlands

Charles N. Rotimi, NHGRI, National Institutes of Health, USA
Global Genomic Diversity: History, Adaptation and Health

12:00—17:00
On Own for Lunch

12:00—13:00
Poster Setup

Victoria Ballroom
13:00—22:00
Poster Viewing

Victoria Ballroom
15:00—16:30
Workshop: Impact of Animal Pathogens on Human Health

Victoria Ballroom
* Evan E. Eichler, HHMI/University of Washington, USA

Jeremaih Okoro Ijomanta, National Veterinary Research Institute, Nigeria
Continuous Circulation of Human-Derived Pandemic H1N1pdm09 Influenza Virus in Nigerian Pigs: Implication for Public Health and Pandemic Preparedness

Kolawole Elijah Oladipo, Adeleke University, Nigeria
Genetic Characterization of H5N1 Influenza A Virus Isolated from Pigs in Ogbomoso, Nigeria

Patricia Ihuaku Otuh, University of Ibadan, Nigeria
Molecular Analyses Unravel Mycobactrium ulcerans Transmission Pathway from Animal Host and Environment to Human in Ogun State, Nigeria

Abdul Walusansa, Islamic University in Uganda, Uganda
Non-Typhoidal Salmonella and Zoonotic E. coli as Potential Drivers of Antimicrobial Resistance in Pastoralist Communities in Kasese District, Uganda

Oluwatoyin Modupe Aladejana, Kings University Odeomu, Nigeria
Occurrence and Multiple-Antibiotics Resistance Profile of Enterobacteriaceae Isolated from Bats Faecal Samples in Osun State, Nigeria

16:30—17:00
Coffee Available

Victoria Ballroom Foyer
17:00—19:00
Human Translational Genomics
Meeting has ended...abstracts no longer viewable online.

Victoria Ballroom
* Christian T. Happi, Redeemer's University, Nigeria

Han G. Brunner, Radboud Maastricht University Medical Center, Netherlands
Genetic Diagnosis of Intellectual Disability

Brunhilde Wirth, University Hospital Cologne, Germany
Therapeutic Approaches to SMA: In the Challenges is a Solution

Lea M. Starita, University of Washington, USA
Using Multiplexed Functional Assays to Understand the Effects of Genetic Variation

Mohamed Z. Alimohamed, University Medical Center Groningen, Netherlands
Short Talk: Routine Use of Targeted NGS Panel in a Dutch Cardiomyopathy Cohort

Jorge Da Rocha, University of the Witwatersrand, South Africa
Short Talk: Addressing Cancer Treatment in an African Setting: A Bioinformatics Analysis of Pharmacogenomically Relevant Variants

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Victoria Ballroom Foyer
19:30—22:00
Poster Session 1

Victoria Ballroom

TUESDAY, NOVEMBER 27

09:00—12:00
Livestock Translational Genomics
Meeting has ended...abstracts no longer viewable online.

Victoria Ballroom
* Farai C. Muchadeyi, Agricultural Research Council, South Africa

Michel A.J. Georges, University of Liège, Belgium
Translation of Animal Genomics to Health: European Perspective

Susan J. Lamont, Iowa State University, USA
Genomics to Enhance Poultry Health Using Biodiversity

Coffee Break

Appolinaire Djikeng, Centre for Tropical Livestock Genetics and Health, University of Edinburgh, UK
Development of Genomic-Based Tools and Resources for Tropical Animal Productivity and Resilience-Talk to be Delivered by John Hickey

Vivien Jepchirchir Chebii, Nelson Mandela African Institution of Science and Technology, Tanzania
Short Talk: Exploring Association of Copy Number Variations in Wild African Goats (Capra nubiana) Adaptations

Edward J. Smith, Virginia Polytechnic Institute and State University, USA
Genomic Characterization of Zambian Indigenous Cattle Breeds

12:00—17:00
On Own for Lunch

12:00—13:00
Poster Setup

Victoria Ballroom
13:00—22:00
Poster Viewing

Victoria Ballroom
16:30—17:00
Coffee Available

Victoria Ballroom Foyer
17:00—19:00
Technological Innovations for Tomorrow
Meeting has ended...abstracts no longer viewable online.

Victoria Ballroom
* Niklas Blomberg, ELIXIR Europe, UK

Christian T. Happi, Redeemer's University, Nigeria
Genomics in Stemming the Tide of Infectious Epidemics

Simon Lillico, University of Edinburgh, UK
Editing Livestock Genomes: Harnessing and Expanding Genomic Diversity

Luísa Pereira, Institute of Molecular Pathology and Immunology of the University of Porto, Portugal
The Power of Local Ancestry Inference Algorithms in Mapping Candidate Genes: The Case Study of African Ancestry Protection against Hemorrhagic Dengue Fever

Martha Nginya, US Army Medical Research Directorate, Kenya
Short Talk: Evaluation of Plasmodium falciparum Histidine-Rich Protein 2 and 3 Gene Deletions in Kenya

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Victoria Ballroom Foyer
19:30—22:00
Poster Session 2

Victoria Ballroom

WEDNESDAY, NOVEMBER 28

09:00—12:00
Solutions for Implementation of Genomic Tests
Meeting has ended...abstracts no longer viewable online.

Victoria Ballroom
* Michèle Ramsay, University of Witwatersrand, South Africa

Farai C. Muchadeyi, Agricultural Research Council, South Africa
Landscape Genomics as a Tool to Understand Genetic Adaptation to Local Conditions

John M. Hickey, University of Edinburgh, UK
Modern Breeding Programs for Local and Global Economies

Coffee Break

David Evans, University of Queensland, Australia
Using Genetics to Investigate the Developmental Origins of Health and Disease

Elizabeth Sibongile Tshabalala, Council of Scientific and Industrial Research, South Africa
Short Talk: Genetic Diversity of Pharmacogenes in a Bantu-Speaking Cohort and Evaluation of Variants Associated with Tenofovir-Induced Nephrotoxicity

Liberata Mwita, Muhimbili University of Health and Allied Sciences, Tanzania
Short Talk: Genome-Wide Associations of Liver Function in Sickle Cell Patients in Tanzania

Chiaka I. Anumudu, University of Ibadan, Nigeria
Short Talk: Improving Schistosomiasis Control Using Genomics and Proteomics Tools

12:00—17:00
On Own for Lunch

12:00—13:00
Poster Setup

Victoria Ballroom
13:00—22:00
Poster Viewing

Victoria Ballroom
15:30—16:30
Virtual Lab Tour: Makerere University
Come view the labs virtually and meet local researchers, Professor Moses Joloba and Dr. David Kateete, representing the following:
Genomics and Molecular Biology facilities
Bioinformatics/Computational Infrastructure
H3Africa Biorepository
Mycobacteriology Laboratory
Immunology facilities
Bacteriology facilities

Victoria Ballroom
16:30—17:00
Coffee Available

Victoria Ballroom Foyer
17:00—19:00
Genomics in Animal and Human Health
Meeting has ended...abstracts no longer viewable online.

Victoria Ballroom
* Han G. Brunner, Radboud Maastricht University Medical Center, Netherlands

Mark S. Fife, Pirbright Institute, UK
Genetic Diversity of Immune Loci in Chickens across Africa and Europe

Michèle Ramsay, University of Witwatersrand, South Africa
Impact of Demographic History and Local Adaptation on Population Diversity and Health: Studies from Africa

Soanandrasana Rahelinirina, Institut Pasteur de Madagascar, Madagascar
Short Talk: First Molecular Detection of Pathogenic Leptospira in Livestock from Slaughterhouses in Madagascar

Isoken H. Igbinosa, University of Benin, Nigeria
Short Talk: Characterization and Detection of Antibiotic Resistance, Virulence Gene Elements and Biofilm Formation in Aeromonas Species Isolated from Cattle

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Victoria Ballroom Foyer
19:30—22:00
Poster Session 3

Victoria Ballroom

THURSDAY, NOVEMBER 29

09:00—12:00
Enablers for Translational Genomics
Meeting has ended...abstracts no longer viewable online.

Victoria Ballroom
Niklas Blomberg, ELIXIR Europe, UK
Global Data Infrastructure for the Scientific Enterprise

Bassirou Bonfoh, CSRS/Afrique One-African Science Partnership for Intervention Research Excellence, Côte D'Ivoire
Genomics: A Half-Full Glass in One Health

Coffee Break

Nicholas Katsanis, Duke University Medical Center, USA
Zebrafish Models for Diseases

Jim Kaufman, University of Cambridge, UK
Short Talk: Typing MHC Haplotypes of African Village Chickens for Structure-Function Studies

Acho Fon Abongwa, University of Yaounde I, Cameroon
Short Talk: Evolution of Plasmodium Falciparum Strains and Resistance Markers in Pregnant Women in Cameroon: 2008-2018

12:00—17:00
On Own for Lunch

14:30—15:30
Panel Discussion: How Do We Build the Ideal Cattle Breeds for Different Ecological Niches?

Victoria Ballroom
* John M. Hickey, University of Edinburgh, UK

Sumaya Y. Kambal, Sudan University of Science and Technology, Sudan
Mitogenomic Analysis of Western Baggara Cattle Breed-Nyalawi Population

Owen Powell, Roslin Institute, University of Edinburgh, Scotland
Can Genomics Enable Genetic Evaluations with Phenotypes Recorded on Smallholder Dairy Farms?

15:30—16:30
Panel Discussion: What Do We Need to Know About Our Ancestry?

Victoria Ballroom
* Han G. Brunner, Radboud Maastricht University Medical Center, Netherlands

16:30—17:00
Coffee Available

Victoria Ballroom Foyer
17:00—18:45
Toward a Perfect World – Emerging Themes
Meeting has ended...abstracts no longer viewable online.

Victoria Ballroom
* Charles N. Rotimi, NHGRI, National Institutes of Health, USA

Elizabeth Marincola, African Academy of Sciences, Kenya
How African Researchers Can Lead the Way in Global Science Communication

Alison L. Van Eenennaam, University of California, Davis, USA
Public Perception of Animal Biotechnology

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Meeting has ended...abstracts no longer viewable online.

Victoria Ballroom
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Poolside Lawn
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Poolside Lawn

FRIDAY, NOVEMBER 30

 
Departure


*Session Chair †Invited, not yet responded.



Keystone Symposia thanks our Sponsor for generously supporting this meeting:

Bill & Melinda Gates Foundation

We gratefully acknowledge additional support from these exhibitors at this conference:

inqaba biotec
Please stop by to meet these exhibitors during the conference.


We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1 R13 HG010287-01

Funding for this conference was made possible (in part) by 1 R13 HG010287-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.


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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


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