| Monday, September 29 |
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3:00 - 7:00 PM
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Registration and Sign-Up for Biopolis Tours
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Stamford Foyer
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6:00 - 10:00 PM
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ISD Board of Directors Meeting
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Enterprise
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| Tuesday, September 30 |
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7:00 - 8:00 AM
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Breakfast
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Canning
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7:00 AM - 12:00 PM
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Poster Setup
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Stamford Foyer
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8:00 - 8:15 AM
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Welcoming Remarks
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Stamford Ballroom
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Lim Chuan Poh,
Chairman, Agency for Science, Technology & Research (A*STAR)
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8:15 - 8:30 AM
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Opening Remarks
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Stamford Ballroom
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David P. Lane,
Experimental Therapeutic Centre
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Hans C. Clevers,
Hubrecht Institute
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8:30 AM - 12:00 PM
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Models of Aging
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Stamford Ballroom
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David P. Lane,
Experimental Therapeutic Centre
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Jan H. J. Hoeijmakers,
Erasmus Medical Center
DNA Repair and the Connection between Cancer and Aging
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Lawrence A. Donehower,
Baylor College of Medicine
Insights into Stem Cells and Aging Provided by A P53 Mutant Mouse
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Heidi Scrable,
University of Virginia
p53 and IGF: An Ancient Connection
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Mary Ellen Perry,
OPASI, OD, National Institutes of Health
p53 and Aging in Experimental Animals
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9:40 - 10:00 AM
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Coffee Break
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Stamford Foyer
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12:00 - 1:00 PM
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Lunch
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Canning
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1:00 - 2:00 PM
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ISD Award Lecture: Anne McLaren Memorial Lecturer
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Stamford Ballroom
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Hans C. Clevers,
Hubrecht Institute
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Magdalena Zernicka-Goetz,
University of Cambridge
Cell Fate, Plasticity and Pluripotency in the Early Mouse embryo
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2:00 - 2:30 PM
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Coffee Available
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Stamford Foyer
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2:30 - 4:00 PM
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Regulating Tumor Suppression
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Stamford Ballroom
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Hans C. Clevers,
Hubrecht Institute
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Gerard I. Evan,
University of California, San Francisco
Switchable Tumor Suppression Models to Control Cancer and Aging
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Alea A. Mills,
Cold Spring Harbor Laboratory
p63 Deficiency and Aging
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4:00 - 6:00 PM
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Poster Session 1
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Stamford Foyer
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5:00 - 6:00 PM
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Social Hour
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Stamford Foyer
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| Wednesday, October 1 |
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7:00 - 8:00 AM
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Breakfast
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Canning
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7:00 AM - 12:00 PM
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Poster Setup
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Stamford Foyer
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8:00 - 11:30 AM
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Signaling Pathways in Cancer and Development
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Stamford Ballroom
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*
Jean-Paul Thiery,
Institute of Molecular and Cellular Biology
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Hans C. Clevers,
Hubrecht Institute
Identification of Stem Cells in Small Intestine and Colon by a Single Marker Gene LGR5
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Yoshiaki Ito,
Institute of Molecular and Cell Biology
RUNX3, a Novel Gate Keeper of Colon Carcinogenesis
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Vinay B. Tergaonkar,
Institute of Molecular and Cell Biology
New Controls of the NF-kappa B Pathway
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Michael Karin,
University of California, San Diego
Inflammatory Processes in Metastatic Progression
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9:40 - 10:00 AM
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Coffee Break
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Stamford Foyer
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11:30 AM - 12:30 PM
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Lunch
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Canning
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12:30 - 2:30 PM
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Poster Session 2
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Stamford Foyer
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2:00 - 2:30 PM
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Coffee Available
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Stamford Foyer
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2:30 - 4:30 PM
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Counting Stem Cells
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Stamford Ballroom
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Gerard I. Evan,
University of California, San Francisco
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Connie J. Eaves,
British Columbia Cancer Agency
Title to be Determined
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Andrei V. Gudkov,
Roswell Park Cancer Institute
Saving Stem Cells to Survive Radiation
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Hongyan Wang,
Duke-NUS Graduate Medical School Singapore
Short Talk: Brain Tumor Suppressors and Neural Stem Cell Self-Renewal in Drosophila
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5:00 - 6:00 PM
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ISD Membership Meeting
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Stamford Ballroom
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| Thursday, October 2 |
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7:00 - 8:00 AM
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Breakfast
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Canning
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7:00 AM - 12:00 PM
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Poster Setup
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Stamford Foyer
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8:00 - 9:00 AM
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Keynote Address
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Stamford Ballroom
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Neal G. Copeland,
Institute of Molecular and Cell Biology
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Arnold J. Levine,
Institute for Advanced Study
Single Nucleotide Polymorphisms in the p53 Pathway
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9:00 - 11:30 AM
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New Models to Find Novel Cancer and Aging Pathways
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Stamford Ballroom
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Arnold J. Levine,
Institute for Advanced Study
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Xin Lu,
Ludwig Institute for Cancer Research
ASPP2 Mediates Senescence and Inhibits Autophagy and Tumourgenicity Induced by H-RasV12
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Neal G. Copeland,
Institute of Molecular and Cell Biology
Harnessing Transposons for Cancer Gene Discovery
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Edison T. Liu,
Genome Institute of Singapore
Comprehensive Identification of Genomic Rearrangements in Human Cancer
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9:00 - 9:20 AM
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Coffee Break
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Stamford Foyer
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11:30 AM - 12:30 PM
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Lunch
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Canning
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12:30 - 2:30 PM
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Poster Session 3
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Stamford Foyer
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2:00 - 2:30 PM
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Coffee Available
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Stamford Foyer
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2:30 - 4:30 PM
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New Targets and Therapeutic Approaches to Cancer and Aging
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Stamford Ballroom
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Xin Lu,
Ludwig Institute for Cancer Research
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Gregory L. Verdine,
Harvard University
Drugging “Undruggable” Targets in Cancer
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David P. Lane,
Experimental Therapeutic Centre
Small Molecule Switches to Control p53 Activity
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Axel Ullrich,
Max Planck Institute of Biochemistry
The Singapore OncoGenome Project as Part of an Effort to Develop a Portfolio of Targeted Cancer Therapeutics
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| Friday, October 3 |
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7:00 - 8:00 AM
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Breakfast
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Canning
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7:30 - 8:30 AM
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Transfer to Biopolis
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8:30 - 10:30 AM
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Cancer Stem Cells
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Biopolis
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Xin Lu,
Ludwig Institute for Cancer Research
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Sean J. Morrison,
University of Michigan/HHMI
Cancer Stem Cells in the Hematopoietic System
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Colin L. Stewart,
Institute of Medical Biology
The Lamins and the Functional Architecture of the Nucleus in Disease and Aging
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Daniel G. Tenen,
Harvard Institutes of Medicine, National University of Singapore
Transcription Factor C/EBP alpha Regulates Hematopoietic Stem Cell Proliferation and Maintenance during Aging
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10:30 - 11:00 AM
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Coffee Break
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Biopolis Foyer
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11:00 AM - 12:00 PM
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ISD Award Lecture: Jean Brachet Memorial Lecturer
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Biopolis
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Hans C. Clevers,
Hubrecht Institute
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Giulio Cossu,
University of Milan
Towards Cell Therapy for Muscular Dystrophies
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12:00 - 1:00 PM
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Lunch Catered by Biopolis
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Biopolis
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12:30 - 2:00 PM
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Optional Tour of Biopolis
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12:30 - 2:00 PM
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Transfer to Hotel
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2:30 - 3:00 PM
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Coffee Available
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Stamford Foyer
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3:00 - 4:45 PM
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More Adult Stem Cells in the Self-Renewing Tissues
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Stamford Ballroom
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Davor Solter,
Institute of Medical Biology
Preformation Versus Epigenesis in Driving Mammalian Development
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Jean-Paul Thiery,
Institute of Molecular and Cellular Biology
Potentiality of Mammary Epithelial Cells with a Basal Phenotype
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4:45 - 5:00 PM
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Meeting Sum Up
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Stamford Ballroom
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Xin Lu,
Ludwig Institute for Cancer Research
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Arnold J. Levine,
Institute for Advanced Study
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5:00 - 6:00 PM
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Social Hour
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Stamford Foyer
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| Saturday, October 4 |
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Departure
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