Keystone Symposia
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Please note: All programs are subject to change. Check this site for updates.

This meeting is part of the Global Health Series

Continuing Medical Education (CME) credits are available.



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Infectious Diseases
LANGUAGE NOTE: This meeting will be conducted in English.
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Meeting Program

To view program in "24 hour" time (international) click here.


Sunday, January 25
3:00 - 7:30 PM Registration Longs Peak Foyer
6:30 - 7:30 PM Refreshments Longs Peak Foyer
7:30 - 8:30 PM Keynote Address
Registered attendees for this meeting can view Abstracts for this session starting on 12/25/2008 		Grays Peak / Longs Peak
Douglas B. Young, Imperial College London, UK
Tying it all Together: Mice to Humans
Monday, January 26
7:00 - 8:00 AM Breakfast Quandary 1-3
8:00 - 11:00 AM Life and Death within the Phagocyte
Registered attendees for this meeting can view Abstracts for this session starting on 12/25/2008 		Grays / Longs Peak
Vojo Deretic, University of New Mexico Health Sciences Center, USA
Autophagy in TB
David G. Russell, Cornell University, USA
Cues and Responses in the Intracellular Infection
Ulrich E. Schaible, London School of Hygiene & Tropical Medicine, UK
The Consequences of Intracellular Release of Antigen
Sabine Ehrt, Weill Cornell Medical College, USA
Mycobacterial Survival Strategies in the Phagosome
9:20 - 9:40 AM Coffee Break Longs Peak Foyer
11:00 AM- 1:00 PM Poster Setup Quandary 1-3
11:00 AM- On Own for Lunch
1:00 - 10:00 PM Poster Viewing Quandary 1-3
4:30 - 5:00 PM Coffee Available Longs Peak Foyer
5:00 - 7:00 PM Early/Innate Immune Responses to TB
Registered attendees for this meeting can view Abstracts for this session starting on 12/25/2008 		Grays / Longs Peak
Valerie F. Quesniaux, Centre National de la Recherche Scientifique, France
Toll-like Receptors in Tuberculosis
Clifford V. Harding, Case Western Reserve University, USA
Regulation of APCs and Class II MHC by TLRs and Mycobacterium tuberculosis
Speaker to be Announced,
Short Talk to be Chosen from Abstracts,
7:00 - 8:00 PM Social Hour w/ Lite Bites Quandary 1-3
7:30 - 10:00 PM Poster Session 1
Registered attendees for this meeting can view Abstracts for this session starting on 12/25/2008 		Quandary 1-3
Tuesday, January 27
7:00 - 8:00 AM Breakfast Quandary 1-3
8:00 - 11:00 AM Key Pathways in Bacterial Metabolism
Registered attendees for this meeting can view Abstracts for this session starting on 12/25/2008 		Grays / Longs Peak
Sandhya S. Visweswariah, Indian Institute of Science, India
Adenylate Cyclases and the Regulator CAMP
Valerie Mizrahi, University of the Witwatersrand - MMRU, South Africa
Novel and Vulnerable Pathways of DNA Metabolism in Mycobacteria
Jeffery S. Cox, University of California, San Francisco, USA
Protein Secretion, Novel and Conserved Systems
Carolyn R. Bertozzi, University of California, Berkeley, USA
Mycobacterial Sulfation Pathways
9:20 - 9:40 AM Coffee Break Longs Peak Foyer
11:00 AM- 1:00 PM Poster Setup Quandary 1-3
11:00 AM- On Own for Lunch
1:00 - 10:00 PM Poster Viewing Quandary 1-3
2:30 - 4:30 PM Workshop on TB Drug Discovery: Connecting Academia and Industry
Registered attendees for this meeting can view Abstracts for this session starting on 12/25/2008 		Grays Peak / Longs Peak
Ken Duncan, Bill & Melinda Gates Foundation, USA
Jose F. Garcia-Bustos, GlaxoSmithKline, Spain
TB Drug Discovery Projects at GSK
Tanjore S. Balganesh, AstraZeneca India Pvt Ltd, India
Koen Andries, Tibotec, Belgium
Makoto Matsumoto, Otsuka Pharmaceutical Co. Ltd., Japan
Thomas N.A. Dick, Novartis Institute for Tropical Diseases, Singapore
Connecting Academia and Industry
Melvin Spigelman, Global Alliance for TB Drug Development, USA
James C. Sacchettini, Texas A & M University, USA
Clifton E. Barry III, NIAID, National Institutes of Health, USA
4:30 - 5:00 PM Coffee Available Longs Peak Foyer
5:00 - 7:00 PM Pathology and Transmission of Tuberculosis
Registered attendees for this meeting can view Abstracts for this session starting on 12/25/2008 		Grays / Longs Peak
Elizabeth L. Corbett, London School of Hygiene & Tropical Medicine / Bio Med Research & Training, Zimbabwe
TB Transmission and Susceptibility
Henry Charles Mwandumba, University of Liverpool, UK
Conditions in the Human Lung during Active Tuberculosis
Gary K. Schoolnik, Stanford University, USA
Lessons from Genomics: Disease and Drug Resistance
7:00 - 8:00 PM Social Hour w/ Lite Bites Quandary 1-3
7:30 - 10:00 PM Poster Session 2
Registered attendees for this meeting can view Abstracts for this session starting on 12/25/2008 		Quandary 1-3
Wednesday, January 28
7:00 - 8:00 AM Breakfast Quandary 1-3
8:00 - 11:00 AM Insights from Animal Models: New Approaches
Registered attendees for this meeting can view Abstracts for this session starting on 12/25/2008 		Grays / Longs Peak
Lalita Ramakrishnan, University of Washington, USA
Momitoring and Modulating Early Host-Mycobacterial Interactions in the Transparent Zebrafish
David S. Schneider, Stanford University School of Medicine, USA
Using Drosophila to Identify Virulence Factors
JoAnne L. Flynn, University of Pittsburgh School of Medicine, USA
Latent and Reactivation Tuberculosis
Gilla Kaplan, Public Health Research Institute, UMDNJ, USA
Host-Pathogen Contributions to Pathology
9:20 - 9:40 AM Coffee Break Longs Peak Foyer
11:00 AM- 1:00 PM Poster Setup Quandary 1-3
11:00 AM- On Own for Lunch
1:00 - 10:00 PM Poster Viewing Quandary 1-3
4:30 - 5:00 PM Coffee Available Longs Peak Foyer
5:00 - 7:00 PM Bacterial Response to the Evolving Host Environments
Registered attendees for this meeting can view Abstracts for this session starting on 12/25/2008 		Grays / Longs Peak
Eric J. Rubin, Harvard School of Public Health, USA
What Do All Those Genes Do Anyway?
Helena I. M. Boshoff, NIAID, National Institutes of Health, USA
How Does the Bacterium Respond to the Microenvironment?
William Bishai, Johns Hopkins School of Medicine, USA
Modeling the Granuloma Microenvironment
Short Talk to be Chosen from Abstracts,
7:00 - 8:00 PM Social Hour w/ Lite Bites Quandary 1-3
7:30 - 10:00 PM Poster Session 3
Registered attendees for this meeting can view Abstracts for this session starting on 12/25/2008 		Quandary 1-3
Thursday, January 29
7:00 - 8:00 AM Breakfast Quandary 1-3
8:00 - 11:00 AM Action and Reaction in the Immune Control of Tuberculosis
Registered attendees for this meeting can view Abstracts for this session starting on 12/25/2008 		Grays / Longs Peak
Michael Stephen Glickman, Sloan-Kettering Cancer Institute, USA
Bacterial Factors in Immune Modulation
Denise Ellen Kirschner, University of Michigan, USA
A Multi-Scale Peek at Granuloma Formation in TB
Katerina Heran Darwin, New York University School of Medicine, USA
Discovery of a Ubiquitin-like Protein Involved in the Proteasome Pathway of Mycobacterium tuberculosis
Speaker to be Announced,
9:20 - 9:40 AM Coffee Break Longs Peak Foyer
11:00 AM- On Own for Lunch
4:30 - 5:00 PM Coffee Available Longs Peak Foyer
5:00 - 7:00 PM Bacterial Physiology and Drug Targets
Registered attendees for this meeting can view Abstracts for this session starting on 12/25/2008 		Grays / Longs Peak
Thomas N.A. Dick, Novartis Institute for Tropical Diseases, Singapore
Metabolism as the Road to Targets and Drug Discovery
James C. Sacchettini, Texas A & M University, USA
Drug Design through Structure
Clifton E. Barry III, NIAID, National Institutes of Health, USA
Why We Don't Have Good Targets
7:00 - 8:00 PM Social Hour w/ Lite Bites Quandary 1-3
8:00 - 11:00 PM Entertainment Quandary 1-3
Friday, January 30
Departure
      *=Session Chair     †=Speaker invited, not yet responded.


Keystone Symposia would like to thank the sponsor of this meeting for their generous support:
We gratefully acknowledge additional support for this conference from:



Novartis Institute for Tropical Diseases Pte Ltd


We gratefully acknowledge the companies that provide Keystone Symposia with additional meeting support, including marketing and advertising...

Click here to view these companies

Tuberculosis kills 2 million people per year worldwide. Although great strides have been made in the past decade in understanding Mycobacterium tuberculosis, the complexity of the disease necessitates a multi-pronged approach. Translating insights related to host-pathogen interplay and bacterial physiology into treatments is complex, requiring academics and industrial scientists to come together in new and creative ways. In humans the infection is persistent and chronic, yet reactivates into fulminating progressive disease. This, and the shortage of appropriate animal models, form major obstacles to identifying factors that determine disease progression and the extensive pathology associated with transmission. This meeting will focus on basic mechanisms of pathogenesis of Mycobacterium tuberculosis, and how the balance of control of infection within the granuloma is influenced by host and bacterial factors. We will also focus on translating basic mechanistic findings to the development of therapies, and a workshop highlighting academic-industrial partnerships is planned.