Keystone Symposia
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LANGUAGE NOTE: This meeting will be conducted in English.
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Meeting Program

To view program in "24 hour" time (international) click here.


Sunday, March 1
3:00 - 7:30 PM Registration Longs Peak Foyer
6:30 - 7:30 PM Refreshments Longs Peak Foyer
7:30 - 8:30 PM Keynote Address
Registered attendees for this meeting can view Abstracts for this session starting on 02/01/2009
Grays Peak / Longs Peak
Alexander Y. Rudensky, University of Washington, USA
Development and Maintenance of Foxp3+Treg
Monday, March 2
7:00 - 8:00 AM Breakfast Quandary 1-3
8:00 - 11:00 AM Molecular Control of Foxp3+Treg
Registered attendees for this meeting can view Abstracts for this session starting on 02/01/2009
Grays Peak / Longs Peak
Christophe O. Benoist, Joslin Diabetes Center, USA
Treg Genomics
Dan R. Littman, New York University School of Medicine, USA
ROR Gamma T, Foxp3, and the Th17 Lineage
Jochen Huehn, Experimental Immunology, Helmholtz Centre for Infection Research, Germany
Epigenetic Control of the Foxp3 Locus in Regulatory T Cells
Steven F. Ziegler, Benaroya Research Institute, USA
Regulation and Role of Foxp3 in Regulatory T Cells
Short Talk(s) to be Chosen from Abstracts,
9:20 - 9:40 AM Coffee Break Longs Peak Foyer
11:00 AM- 1:00 PM Poster Setup Quandary 1-3
11:00 AM- On Own for Lunch
1:00 - 10:00 PM Poster Viewing Quandary 1-3
2:30 - 4:30 PM Workshop 1
Grays Peak / Longs Peak
Short Talks to be Chosen from Abstracts, , USA
4:30 - 5:00 PM Coffee Available Longs Peak Foyer
5:00 - 7:00 PM Pathways of Thymic and Peripheral Treg Development
Registered attendees for this meeting can view Abstracts for this session starting on 02/01/2009
Grays Peak / Longs Peak
Harald von Boehmer, Harvard Medical School, USA
Prospective Tolerance by Inducing Foxp3+ Treg in Peripheral Lymphoid Tissue
Ludger Klein, University of Munich, Institute for Immunology, Germany
Determinants of Intrathymic regulatory T cell development
Vijay K. Kuchroo, Brigham and Women's Hospital, Harvard Medical School, USA
Role of TGF-β in regulating the balance between pathogenic and regulatory T cells
Megan K. Levings, University of British Columbia, Canada
The Role of FOXP3 in the Development and Function of Human T regulatory Cells
7:00 - 8:00 PM Social Hour w/ Lite Bites Quandary 1-3
7:30 - 10:00 PM Poster Session 1
Registered attendees for this meeting can view Abstracts for this session starting on 02/01/2009
Quandary 1-3
Tuesday, March 3
7:00 - 8:00 AM Breakfast Quandary 1-3
8:00 - 11:00 AM Inducible Regulatory T Cells
Registered attendees for this meeting can view Abstracts for this session starting on 02/01/2009
Grays Peak / Longs Peak
Anne O'Garra, National Institute for Medical Research, UK
IL-10 and Immunoregulation
Dragana Jankovic, NIAID, National Institutes of Health, USA
Highly Polarized Th1 Cells as Regulatory T Cells
Catherine M. Hawrylowicz, King's College London, UK
IL-10 secreting T regulatory cells in allergy and asthma
Wanjun Chen, NIDCR, National Institutes of Health, USA
Role of TGF-beta in Induction and Survival of Treg Cells
Short Talk(s) to be Chosen from Abstracts,
9:20 - 9:40 AM Coffee Break Longs Peak Foyer
11:00 AM- 1:00 PM Poster Setup Quandary 1-3
11:00 AM- On Own for Lunch
1:00 - 10:00 PM Poster Viewing Quandary 1-3
2:30 - 4:30 PM Workshop 2
Grays Peak / Longs Peak
Short Talks to be Chosen from Abstracts, , USA
4:30 - 5:00 PM Coffee Available Longs Peak Foyer
5:00 - 7:00 PM Local Control by Treg
Registered attendees for this meeting can view Abstracts for this session starting on 02/01/2009
Grays Peak / Longs Peak
Fiona M. Powrie, University of Oxford, UK
Immune Regulation in the Gut
Kathryn Wood, University of Oxford, UK
Role of Treg in Tolerance of Transplanted Organs
Juan J. Lafaille, New York University School of Medicine, USA
Control of Gut Homeostasis by Induced Treg
Short Talk to be Chosen from Abstracts,
7:00 - 8:00 PM Social Hour w/ Lite Bites Quandary 1-3
7:30 - 10:00 PM Poster Session 2
Registered attendees for this meeting can view Abstracts for this session starting on 02/01/2009
Quandary 1-3
Wednesday, March 4
7:00 - 8:00 AM Breakfast Quandary 1-3
8:00 - 11:00 AM Treg in Infectious Diseases/Hygiene Hypothesis
Registered attendees for this meeting can view Abstracts for this session starting on 02/01/2009
Grays Peak / Longs Peak
Yasmine Belkaid, NIAID, National Institutes of Health, USA
Plasticity of Regulatory T Cells During Infections
Eleanor M. Riley, London School of Hygiene and Tropical Medicine, UK
T cell-mediated Immunoregulation during Human and Murine Malaria Infections
Richard M. Maizels, University of Edinburgh, UK
Treg Induced by Helminths
Bruce D. Walker, Massachusetts General Hospital, USA
Immune Regulation of Viral Infection
Short Talk(s) to be Chosen from Abstracts,
9:20 - 9:40 AM Coffee Break Longs Peak Foyer
11:00 AM- 1:00 PM Poster Setup Quandary 1-3
11:00 AM- On Own for Lunch
1:00 - 10:00 PM Poster Viewing Quandary 1-3
2:30 - 4:30 PM Workshop 3
Grays Peak / Longs Peak
Short Talks to be Chosen from Abstracts, , USA
4:30 - 5:00 PM Coffee Available Longs Peak Foyer
5:00 - 7:00 PM Targets and Mechanisms of Suppression
Registered attendees for this meeting can view Abstracts for this session starting on 02/01/2009
Grays Peak / Longs Peak
Shimon Sakaguchi, Institute for Frontier Medical Sciences, Kyoto University, Japan
Manipulation of Treg for Anti Tumor Therapy
Dario A.A. Vignali, St. Jude Children's Research Hospital, USA
IL-35 and Regulatory T Cell Function
Kirsten Falk, Max Delbruck Center for Molecular Medicine, Germany
Effector/Memory Treg Cells (TREM): Extracellular ATP and Immune Suppression
Short Talk to be Chosen from Abstracts,
7:00 - 8:00 PM Social Hour w/ Lite Bites Quandary 1-3
7:30 - 10:00 PM Poster Session 3
Registered attendees for this meeting can view Abstracts for this session starting on 02/01/2009
Quandary 1-3
Thursday, March 5
7:00 - 8:00 AM Breakfast Quandary 1-3
8:00 - 11:00 AM Treg Homeostasis and Survival
Registered attendees for this meeting can view Abstracts for this session starting on 02/01/2009
Grays Peak / Longs Peak
Jeffrey A. Bluestone, University of California, San Francisco, USA
Natural T regulatory cell instability leads to pathogenicity
Arne N. Akbar, University College London, UK
The Kinetics of CD4+Foxp3+ T Cell Accumulation during a Human Cutaneous Antigen-Specific Memory Response in vivo
Talal A. Chatila, University of California, Los Angeles, USA
Dual Requirement for Natural and Induced Regulatory T Cells in Peripheral Tolerance
Daniel Campbell, Benaroya Research Institute, USA
T-bet controls regulatory T cell homeostasis and function during type-1 inflammation
Short Talk(s) to be Chosen from Abstracts,
9:20 - 9:40 AM Coffee Break Longs Peak Foyer
11:00 AM- On Own for Lunch
4:30 - 5:00 PM Coffee Available Longs Peak Foyer
5:00 - 7:00 PM Manipulation of Treg as Therapeutic Approach
Registered attendees for this meeting can view Abstracts for this session starting on 02/01/2009
Grays Peak / Longs Peak
Ethan M. Shevach, NIAID, National Institutes of Health, USA
Control of Immune Responses by Natural and Adaptive Regulatory T Cells
Maria Grazia Roncarolo, San Raffaele Telethon Institute for Gene Therapy, Italy
Tr1 from Discovery to Clinical Applications
Kingston H. G. Mills, Trinity College, Dublin, Ireland
Immunotherapeutic Approaches Based on Manipulating Treg versus Th17 Cells
7:00 - 8:00 PM Social Hour w/ Lite Bites Quandary 1-3
8:00 - 11:00 PM Entertainment Quandary 1-3
Friday, March 6
Departure
      *=Session Chair     †=Speaker invited, not yet responded.



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Over the past few years Regulatory T cells have taken center stage in the field of immunoregulation. Several types of regulatory T cell have been described on the basis of their origin, generation and mechanism of action, with two main subsets identified: naturally occurring FOXP3+ regulatory T cells and inducible regulatory T cells. All types of regulatory T cell, by virtue of their capacity to control the intensity of effector responses, have been shown to play a major role in the control of immune responses at large. This meeting will highlight recent developments in our understanding of the molecular basis for the differentiation of naturally occurring or inducible regulatory T cells. The second goal is to discuss information on the targets, mechanism of action, recruitment and homeostasis of regulatory T cells. The third goal is to discuss recent advances in our understanding of the conditions favoring the emergence and regulation of these populations and to discuss how these findings are translated in clinical trials.