Keystone Symposia Conference | Extrinsic Control of Tumor Genesis and Progression

Meeting Program

To view program in "24 hour" time (international) click here.

Sunday, March 15
3:00 - 7:30 PM	Registration	Sechelt Foyer
6:30 - 7:30 PM	Refreshments	Waterfront Foyer
7:30 - 8:30 PM	Keynote Address Registered attendees for this meeting can view Abstracts for this session starting on 02/15/2009	Waterfront Ballroom
	Norman F. Boyd, University of Toronto, Canada Mammographic Density and Breast Cancer Risk
Monday, March 16
7:00 - 8:00 AM	Breakfast	Mackenzie Ballroom
8:00 - 11:00 AM	Coding Information within the ECM Registered attendees for this meeting can view Abstracts for this session starting on 02/15/2009	Waterfront Ballroom
	Pepper Jo Schedin, University of Colorado Health Sciences Center, USA Information Conveyed by ECM Proteins in the Mammary Gland
	Speaker to be Announced,

	Valerie Marie Weaver, University of California, San Francisco, USA How Matrix Topology and Stiffness Direct Tumor Progression
	Raghu Kalluri, Harvard Medical School/BIDMC, USA Endogenous Angiogenesis Inhibitors and Fibroblasts Control the Rate of Cancer Progression and Metastasis
9:20 - 9:40 AM	Coffee Break	Waterfront Foyer
11:00 AM- 1:00 PM	Poster Setup	Waterfront Ballroom
11:00 AM-	On Own for Lunch
1:00 - 10:00 PM	Poster Viewing	Waterfront Ballroom
4:30 - 5:00 PM	Coffee Available	Waterfront Foyer
5:00 - 7:00 PM	Stem Cells and Their Niche Registered attendees for this meeting can view Abstracts for this session starting on 02/15/2009	Waterfront Ballroom
	Tannishtha Reya, Duke University Medical Center, USA Imaging Asymmetric Division in Stem Cells and Cancer
	D. Leanne Jones, The Salk Institute for Biological Studies, USA Signaling in Stem Cell Niches: Lessons from the Drosophila Germline


	David V. Schaffer, University of California, Berkeley, USA Molecular Engineering of Synthetic Stem Cell Microenvironments
	Short Talk to be Chosen from Abstracts,
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Waterfront Ballroom
7:30 - 10:00 PM	Poster Session 1 Registered attendees for this meeting can view Abstracts for this session starting on 02/15/2009	Waterfront Ballroom
Tuesday, March 17
7:00 - 8:00 AM	Breakfast	Mackenzie Ballroom
7:00 - 8:00 AM	Poster Setup	Waterfront Ballroom
8:00 - 11:00 AM	Key Pathways in Extrinsic Modulation Registered attendees for this meeting can view Abstracts for this session starting on 02/15/2009	Waterfront Ballroom
	Mary Helen Barcellos-Hoff, New York University, USA Extrinsic Control of Intrinsic DNA Damage Response and the Contribution to Carcinogenesis

	Mary J.C. Hendrix, Children's Memorial Research Center at Northwestern University, USA Reprogramming Metastatic Tumor Cells with an Embryonic Microenvironment:Convergence of Embryonic and Tumorigenic Signaling Pathways
	Harold L. Moses, Vanderbilt University, USA TGF-beta Regulation of the Tumor Microenvironment
	Mona Gauthier, University of Toronto, Canada Stress Response Pathways in the Mammary Gland
9:20 - 9:40 AM	Coffee Break	Waterfront Foyer
11:00 AM- 12:00 PM	Lunch	Waterfront Ballroom
12:00 - 2:30 PM	Poster Session 2 Registered attendees for this meeting can view Abstracts for this session starting on 02/15/2009	Waterfront Ballroom
2:30 - 4:30 PM	Workshop 1	Waterfront Ballroom
	Short Talks to be Chosen from Abstracts, , USA
4:30 - 5:00 PM	Coffee Available	Waterfront Foyer
5:00 - 7:00 PM	Clinical Applications Registered attendees for this meeting can view Abstracts for this session starting on 02/15/2009	Waterfront Ballroom
	Morag Park, McGill University, Canada Stromal Gene Expression Predicts Clinical Outcome in Breast Cancer
	David T. Scadden, Massachusetts General Hospital, USA Hematopoietic stem cell interactions with their microenvironment

	Speaker to be Announced,
	Short Talk to be Chosen from Abstracts,
7:00 PM-	On Own for Dinner
Wednesday, March 18
7:00 - 8:00 AM	Breakfast	Mackenzie Ballroom
8:00 - 11:00 AM	Basic Biology: Molecular Mechanisms Registered attendees for this meeting can view Abstracts for this session starting on 02/15/2009	Waterfront Ballroom
	Speaker to be Announced,

	Luis F. Parada, University of Texas Southwestern Medical Center, USA Talk Title to be Determined
	Thea D. Tlsty, University of California, San Francisco, USA Biologic Basis of Density and Risk
	Elazer Edelman†, Massachusetts Institute of Technology, USA Signaling
9:20 - 9:40 AM	Coffee Break	Waterfront Foyer
11:00 AM- 1:00 PM	Poster Setup	Waterfront Ballroom
11:00 AM-	On Own for Lunch
1:00 - 10:00 PM	Poster Viewing	Waterfront Ballroom
4:30 - 5:00 PM	Coffee Available	Waterfront Foyer
5:00 - 7:00 PM	Tumor Microenvironment Registered attendees for this meeting can view Abstracts for this session starting on 02/15/2009	Waterfront Ballroom
	Kornelia Polyak, Dana-Farber Cancer Institute, USA Regulation of in situ to Invasive Breast Carcinoma Progression
	Mina J. Bissell, Lawrence Berkeley National Laboratory, USA Form Dictates Function
	Zena Werb, University of California, San Francisco, USA Extrinsic and Intrinsic Mechanisms of Malignant Progression
	Short Talk to be Chosen from Abstracts,
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Waterfront Ballroom
7:30 - 10:00 PM	Poster Session 3 Registered attendees for this meeting can view Abstracts for this session starting on 02/15/2009	Waterfront Ballroom
Thursday, March 19
7:00 - 8:00 AM	Breakfast	Mackenzie Ballroom
8:00 - 11:00 AM	Non-Transformed Cells Modulate Transformed Cells Registered attendees for this meeting can view Abstracts for this session starting on 02/15/2009	Waterfront Ballroom
	Lisa M. Coussens, University of California, San Francisco, USA Tissue-Specific Mechanisms Regulate Pro-Tumor Immunity
	Philipp E. Scherer, University of Texas Southwestern Medical Center, USA Adipocyte Signals
	Judith Campisi, Lawrence Berkeley National Laboratory, USA The Two Faces of Cellular Senescence
	Sylvaine Cases, Cytokinetics, Inc., USA Role of Adipocytes in Mammary Gland Development and Breast Cancer: Lessons form DGAT1-deficient Mice
9:20 - 9:40 AM	Coffee Break	Waterfront Foyer
11:00 AM-	On Own for Lunch
2:30 - 4:30 PM	Workshop 2	Waterfront Ballroom
	Short Talks to be Chosen from Abstracts, , USA
4:30 - 5:00 PM	Coffee Available	Waterfront Foyer
5:00 - 7:00 PM	Progression to Metastasis Registered attendees for this meeting can view Abstracts for this session starting on 02/15/2009	Waterfront Ballroom
	Douglas Hanahan, University of California, San Francisco, USA Oncogenic Switches

	Charlotte Kuperwasser, Tufts University School of Medicine, New England, USA Systemic Stromal Effects of Estrogen Promote the Growth of Estrogen Receptor-Negative Cancers
	Robert A. Weinberg, Whitehead Institute for Biomedical Research, USA Metastatic Modulation
	Short Talk to be Chosen from Abstracts,
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Waterfront Ballroom
8:00 - 11:00 PM	Entertainment	Waterfront Ballroom
Friday, March 20
	Departure
*=Session Chair †=Speaker invited, not yet responded.

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It has long been known that the interactions between cells and their respective microenvironments are instructive and necessary in proper development. Cell-environment interactions play complex roles in organ homeostasis and, when altered, disease. Increasing evidence now suggests that the microenvironment also modulates critical aspects of the genesis and progression of tumors. For example, initiation, progression and even control of metastasis and latency are governed by these interactions. This modulation is most likely brought about through both genetic and epigenetic mechanisms. Currently, the signaling pathways and mechanisms of regulation are mostly unknown. This conference will bring together leaders in this field to discuss current problems and strategize on the clinical application of new insights.

Extrinsic Control of Tumor Genesis and Progression (C8)