Keystone Symposia Conference | Complications of Diabetes and Obesity

Meeting Program

To view program in "24 hour" time (international) click here.

Tuesday, February 24
3:00 - 7:30 PM	Registration	BC Foyer
6:30 - 7:30 PM	Refreshments	Pacific Ballroom
7:30 - 8:30 PM	Keynote Address (Joint) Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009	British Columbia Ballroom
	Joseph Loscalzo, Brigham and Women's Hospital/Harvard Medical School, USA Redox Dysregulation in Vascular Disease
Wednesday, February 25
7:00 - 8:00 AM	Breakfast	Pacific Ballroom
8:00 - 11:00 AM	Glucose and Other Metabolites: Actions on Target Cells Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009	Columbia Ballroom
	Michael A. Brownlee, Albert Einstein College of Medicine, USA Unifying Mechanisms and the Complications of Diabetes
	Ann Marie Schmidt, Columbia University, USA RAGE, Inflammation and the Complications of Diabetes
	George L. King, Joslin Diabetes Center, USA Protein Kinase C and the Complications of Diabetes
	Paul Fernyhough, St Boniface Research Centre, Canada Mitochondrial Stress and the Pathogenesis of Diabetic Neuropathy
	Short Talk(s) to be Chosen from Abstracts,
Following Session is for Vasculature (J8)
8:00 - 11:00 AM	Endothelial Cell Signaling Components Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009 The Endothelial Cell: New Molecules and Markers	British Ballroom
	Brant M. Weinstein, NICHD, National Institutes of Health, USA Regulation of Developmental Angiogenesis and Lymphangiogenesis

	Mark S. Taylor, University of South Alabama College of Medicine, USA Localized Calcium Signaling in Endothelial Cells
	Lothar A. Blatter, Rush University Chicago, USA Calcium and NFAT Signaling in Vascular Endothelial Cells
	Luisa Iruela-Arispe, UCLA Molecular, USA Intracrine VEGF Signaling in Endothelial Cells
	Short Talk(s) to be Chosen from Abstracts,
9:20 - 9:40 AM	Coffee Break	BC Foyer
11:00 AM- 1:00 PM	Poster Setup	Pacific Ballroom
11:00 AM-	On Own for Lunch
1:00 - 10:00 PM	Poster Viewing	Pacific Ballroom
2:30 - 4:30 PM	Workshop 1: Techniques (Joint) Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009	Columbia Ballroom
4:30 - 5:00 PM	Coffee Available	BC Foyer
5:00 - 7:00 PM	Insulin Resistance and Actions Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009	Columbia Ballroom
	C. Ronald Kahn, Joslin Diabetes Center, USA Insulin Actions and Cardiovascular Pathologies
	Michael James Quon, National Institutes of Health, USA Reciprocal Relationships Between Insulin Resistance and Endothelial Dysfunction: From Cells to Humans
	Nir Barzilai, Albert Einstein College of Medicine, USA Aging and Insulin Resistance
	Short Talk to be Chosen from Abstracts,
Following Session is for Vasculature (J8)
5:00 - 7:00 PM	Endothelial Cell Interactions and Targeting Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009 The Endothelial Cell: New Molecules and Markers	British Ballroom
	Sarah Y. Yuan, University of California, Davis, USA Endothelial Junction and Vascular Permeability
	Michel Feletou, Institut de Recherches Servier, France The Endothelium as a Target for Drug Development
	Wolfgang F. Graier, Medical University of Graz, Austria Endothelial Mitochondria as Key Players for Endothelial Cell Function and Dysfunction
	Short Talk to be Chosen from Abstracts,
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Pacific Ballroom
7:30 - 10:00 PM	Poster Session 1 Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009	Pacific Ballroom
Thursday, February 26
7:00 - 8:00 AM	Breakfast	Pacific Ballroom
7:00 - 8:00 AM	Poster Setup	Pacific Ballroom
8:00 - 11:00 AM	Inflammation and Immunity: Links to Diabetes and Obesity Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009	Columbia Ballroom
	Anthony W. Ferrante, Columbia University, USA Inflammatory Mechanisms and Obesity
	Christopher K. Glass, University of California, San Diego, USA PPARs, Inflammatory Signaling and Insulin Resistance
	Douglas Golenbock, University of Massachusetts Medical School, USA Toll Like Receptors - Linking Innate and Adaptive Immunity

	Ishwarlal Jialal, University of California, Davis, USA Diabetes(both Type1 &2 ) is a Pro-Inflammatory State: Implications for Vascular Complications
	Short Talk(s) to be Chosen from Abstracts,
Following Session is for Vasculature (J8)
8:00 - 11:00 AM	Vascular Smooth Muscle Cell Components and Communicators Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009 Vascular Smooth Muscle Cell Dissection: From Birth to Function	British Ballroom
	Mark W. Majesky, University of North Carolina at Chapel Hill, USA Development of Coronary Smooth Muscle
	Jonathan H. Jaggar, University of Tennessee College of Medicine, USA Mitochondrial Regulation of Arterial Calcium Signaling and Diameter
	William F. Jackson, Michigan State University, USA Vascular Ion Channels: Will the Key Players Please Stand Up?
	Karen Lounsbury, University of Vermont, USA Phenotype Switching in Vascular Smooth Muscle Cells: A Complex Interaction between Transcription Factors
	Short Talk(s) to be Chosen from Abstracts,
9:20 - 9:40 AM	Coffee Break	BC Foyer
11:00 AM- 12:00 PM	Lunch	Pacific Ballroom
12:00 - 2:30 PM	Poster Session 2 Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009	Pacific Ballroom
2:30 - 4:30 PM	Workshop 2: Funding for the Young Cardiovascular and Diabetes Investigator (Joint) Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009	Columbia Ballroom
4:30 - 5:00 PM	Coffee Available	BC Foyer
5:00 - 7:00 PM	Regeneration and Diabetes Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009	Columbia Ballroom
	Douglas Zochodne, University of Calgary, Canada Diabetes and Regenerative Failure of Peripheral Neurons
	Martin Friedlander, The Scripps Research Institute, USA Cell-Based Therapies for Diabetic Retinopathy
	Omaida C. Velazquez, University of Miami, Jackson Memorial Hospital, USA The Potential Role of Hyperoxia and Endothelial Progenitor Cell Mobilization in Diabetic Wound Healing
	Short Talk to be Chosen from Abstracts,
Following Session is for Vasculature (J8)
5:00 - 7:00 PM	New Insights into Mechanisms of Vascular Contraction Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009 Vascular Smooth Muscle Cell Dissection: From Birth to Function	British Ballroom
	Richard J. Paul, University of Cincinnati College of Medicine, USA It’s Not Just [Ca2+]i Anymore or Rho, ROS and Hypoxic Vasorelaxation
	R. Clinton Webb, Medical College of Georgia, USA New Insights into Mechanisms of Vascular Contraction: STIM-1/Orai-1 Pathway and Vascular Dysfunction
	W. Gil Wier, University of Maryland School of Medicine, USA Genetically Encoded FRET-based Sensors Allow Visualization of Signal Transduction in Individual Cells of Intact Arteries.
	Short Talk to be Chosen from Abstracts,
7:00 PM-	On Own for Dinner
Friday, February 27
7:00 - 8:00 AM	Breakfast	Pacific Ballroom
8:00 - 11:00 AM	Novel Targets and Treatments for Diabetes and its Complications Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009	Columbia Ballroom
	Lloyd P. Aiello, Joslin Diabetes Center, USA Novel Targets and Treatments for Diabetic Retinopathy and Macular Edema
	Kumar Sharma, University of California San Diego, USA A Systems Biology Understanding of Diabetic Nephropathy Based on Novel Anti-Fibrosis Treatments and Biomarkers
	Ravichandran Ramasamy, Columbia University, USA ALDOSE REDUCTASE & RAGE: KEY TRAGETS FOR CARDIOPROTECTIVE INTERVENTIONS IN DIABETES
	Nobuyo Maeda, University of North Carolina, USA Antioxidant Defense against Diabetic Cardiovascular Disease
	Short Talk(s) to be Chosen from Abstracts,
Following Session is for Vasculature (J8)
8:00 - 11:00 AM	Influences of Neighboring Cells on Vascular Smooth Muscle Function Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009 Integration of the Vascular Components: The Whole is Greater then the Sum of the Parts	British Ballroom

	Jessica Andrea Filosa, Medical College of Georgia, USA Interpreting the communication between cerebral microvessels and astrocytes in the brain
	Ronald J. Korthuis, University of Missouri, USA Postischemic Arteriolar Dysfunction is Dependent on Venular Leukocyte Adhesion and Mast Cells: Role of Cell-Cell Communication

	Brant Isakson, University of Virginia, USA Coordinated Function of Endothelial and Vascular Smooth Muscle Cells
	Gregory Fink, Michigan State University, USA Arteries and Veins: Substrates for Disparate But Integrated Sympathetic Control
	Short Talk(s) to be Chosen from Abstracts,
9:20 - 9:40 AM	Coffee Break	BC Foyer
11:00 AM- 1:00 PM	Poster Setup	Pacific Ballroom
11:00 AM-	On Own for Lunch
1:00 - 10:00 PM	Poster Viewing	Pacific Ballroom
4:30 - 5:00 PM	Coffee Available	BC Foyer
5:00 - 7:00 PM	Cellular Mechanisms, Shaping the Nature and Severity of Complications Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009	Columbia Ballroom
	Erwin P. Böttinger, Mount Sinai School of Medicine, USA Impact of Podocyte Injury in Diabetes
	Thomas M. Coffman, Duke University Medical Center, USA Impact of Hypertension and the Renin-Angiotensin System


	Geoffrey Cash Gurtner, Stanford University, USA Aging and Vascular Repair
	Short Talk to be Chosen from Abstracts,
Following Session is for Vasculature (J8)
5:00 - 7:00 PM	Synthesis of the Whole Vessel Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009 Integration of the Vascular Components: The Whole is Greater then the Sum of the Parts	British Ballroom
	David A. Robertson, Vanderbilt University Medical Center, USA Human Phenotypes and Animal Knockout Models of Genetic Autonomic Disorders
	Paul L. Hermonat, University of Arkansas for Medical Sciences, USA Viral delivery of therapeutic genes for vascular pathologies.
	David D. Gutterman, Medical College of Wisconsin, USA Human Microvascular Function in Disease: Mechanistic Insights
	Short Talk to be Chosen from Abstracts,
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Pacific Ballroom
7:30 - 10:00 PM	Poster Session 3 Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009	Pacific Ballroom
Saturday, February 28
7:00 - 8:00 AM	Breakfast	Pacific Ballroom
8:00 - 11:00 AM	Hypertension and Angiogenesis - Responses to Vascular Injury/Genomics - Disease Models and Human Genomics (Joint) Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009	British Columbia Ballroom
	Susan Quaggin, Samuel Lunenfeld Research Institute, Canada Angiogenesis and Diabetic Nephropathy
	Maria B. Grant, University of Florida, USA Vascular Repair Strategies for Diabetic Retinopathy- Mobilization and Differentiation of Hematopoietic Stem Cell by IGFBP-3
	Geert W. Schmid-Schönbein, University of California, San Diego, USA A Molecular Mechanism for Blood Pressure Elevation, Type II Diabetes, Immune Suppression and Microvascular Rarefaction in the Spontaneously Hypertensive Rat
	Frank Chip Brosius III, University of Michigan, USA Mice and Metabolic Syndrome: Models and Consequences of Altered Glucose Uptake
	Short Talk(s) to be Chosen from Abstracts,
9:20 - 9:40 AM	Coffee Break	BC Foyer
11:00 AM-	On Own for Lunch
4:30 - 5:00 PM	Coffee Available	BC Foyer
5:00 - 7:00 PM	Genetics and Epigenetics Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009	Columbia Ballroom
	John Sedor, Case School of Medicine, USA Genetics of Diabetic Nephropathy

	Speaker to be Announced,
	Rama Natarajan, Beckman Research Institute of City of Hope, USA Epigenetics, Metabolic Memory, Inflammation and Diabetic Complications
	Short Talk to be Chosen from Abstracts,
Following Session is for Vasculature (J8)
5:00 - 7:00 PM	Mechanisms and Targeted Treatment of Vascular Pathologies: Focus on Hypertension Registered attendees for this meeting can view Abstracts for this session starting on 01/24/2009 Mechanisms of Vascular Pathologies: Diabetes and Hypertension	British Ballroom
	Andrea D. Eckhart, Thomas Jefferson University, USA Novel Mouse Models for Studying Vascular Contributions to Hypertension
	Nancy J. Rusch, University of Arkansas for Medical Sciences, USA Ion Channel Expression and Function in Hypertension
	Richard A. Cohen, Boston University School of Medicine, USA Redox Regulation of SERCA in Diabetic Vascular Disease
	Short Talk to be Chosen from Abstracts,
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Pacific Ballroom
8:00 - 11:00 PM	Entertainment	Pacific Ballroom
Sunday, March 1
	Departure
*=Session Chair †=Speaker invited, not yet responded.

Keystone Symposia would like to thank the sponsor of this meeting for their generous support:

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge the generous grant for this conference provided by:

National Institutes of Health
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Grant No. 5R13DK076500-03

The contents of this program are solely the responsibility of the Conference Organizers and their speakers and do not necessarily represent the official views of the National Institutes of Health.

We gratefully acknowledge the companies that provide Keystone Symposia with additional meeting support, including marketing and advertising...

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The complications of diabetes and obesity are emerging as major health problems in the United States and world-wide. Obesity-linked complications may lead to the development of insulin resistance and, ultimately, hyperglycemia. Thus, the study of mechanisms underlying and linking these disorders holds promise for the identification of mechanism-targeted therapeutic agents. In addition to frank and often destructive recruitment of immune responses, diabetes and obesity are significantly modified by host and environment factors. Such factors as hypertension, innate aging, failure of effective pro- or anti- angiogenesis programs, genetic and epigenetic factors may influence the phenotype and outcome in diabetes and obesity. The goals of the meeting will be to integrate these concepts in close collaboration with the “Dissecting the Vasculature” concurrent meeting group. Beginning with the vessel, and addressing superimposed and modifying factors, this program will facilitate greater understanding of mechanisms linked to diabetes and its complications and obesity.

Complications of Diabetes and Obesity (J7)