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Joint meeting: Schizophrenia and Bipolar Disorder (X1) (Registration for one meeting allows attendance at either meeting, pending space availability.)


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Neurobiology
LANGUAGE NOTE: This meeting will be conducted in English.
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Meeting Program

To view program in "24 hour" time (international) click here.


Friday, March 6
3:00 - 7:30 PM Registration Longs Peak Foyer
6:30 - 7:30 PM Refreshments Longs Peak Foyer
7:30 - 8:30 PM Keynote Address
Registered attendees for this meeting can view Abstracts for this session starting on 02/06/2009 		Longs Peak
* Xinyu Zhao, University of New Mexico, USA
and
* Peng Jin, Emory University School of Medicine, USA
Opening Remarks
Fred H. Gage, The Salk Institute for Biological Studies, USA
Epigenetic and Genetic Regulation of Neuronal Progenitor Cells
Saturday, March 7
7:00 - 8:00 AM Breakfast Quandary Peak
8:00 - 11:00 AM Epigenetic Mechanisms in Human Biology
Registered attendees for this meeting can view Abstracts for this session starting on 02/06/2009 		Longs Peak
Stephen T. Warren, Emory University School of Medicine, USA
Molecular Basis of Neurodevelopmental Disorders
Speaker to be Announced,
Guoping Fan, University of California, Los Angeles, USA
Epigenetic Regulation in Neuronal Survival and Brain Development
Michael E. Zwick, Emory University School of Medicine, USA
A Genome Sequencing Center in Every Lab: Harnessing Next-Generation Sequencing Technology to Identify Autism Susceptibility Loci
Short Talk(s) to be Chosen from Abstracts,
Following Session is for Schizophrenia and Bipolar Disorder (X1)
8:00 - 11:00 AM Genome-Wide Studies of Disease-Related Variation
Registered attendees for this meeting can view Abstracts for this session starting on 02/06/2009 		Grays Peak
Mark J. Daly†, Harvard Medical School, USA
Overview of Genome-Wide Association Studies, Lessons from other Diseases, and Application to Psychiatric Disorders
Pamela Sklar, Harvard Medical School, Massachusetts General Hospital, USA
Genome-Wide Association Studies of Bipolar Disorder
Patrick F. Sullivan, University of North Carolina, USA
Genome-Wide Association Studies of Schizophrenia
Jonathan Sebat, Cold Spring Harbor Laboratory, USA
Analysis of Genome Copy Number Variation in Psychiatric Disease
Short Talk(s) to be Chosen from Abstracts,
9:20 - 9:40 AM Coffee Break Longs Peak Foyer
11:00 AM- 1:00 PM Poster Setup Quandary Peak
11:00 AM- On Own for Lunch
1:00 - 10:00 PM Poster Viewing Quandary Peak
4:30 - 5:00 PM Coffee Available Longs Peak Foyer
5:00 - 6:10 PM Monogenic Neurodevelopmental Disorders: Rett Syndrome
Registered attendees for this meeting can view Abstracts for this session starting on 02/06/2009 		Longs Peak
David Katz, Case Western Reserve University School of Medicine, USA
Mecp2 and Rett Syndrome
Xinyu Zhao, University of New Mexico, USA
Methyl-CpG Binding Proteins in Neurogenesis and Autism Spectrum Disorders
Following Session is for Schizophrenia and Bipolar Disorder (X1)
5:00 - 7:00 PM Clinical Epidemiology and Etiology
Registered attendees for this meeting can view Abstracts for this session starting on 02/06/2009 		Grays Peak
Peter B. Jones, Cambridge University, UK
Epidemiology and Risk Factors, Shared or Not?
Nick J. Craddock, Cardiff University School of Medicine, UK
The Boundaries of the Phenotypes
Christopher Ross, Johns Hopkins University School of Medicine, USA
Insights from Neurodegeneration: Approaches for Psychiatric Disease
6:10 - 7:15 PM Monogenic Neurodevelopmental Disorders: Fragile X Syndrome
Registered attendees for this meeting can view Abstracts for this session starting on 02/06/2009 		Longs Peak
* David L. Nelson, Baylor College of Medicine, USA
Development of Animal Models for Fragile X Syndrome
Peng Jin, Emory University School of Medicine, USA
Fragile X Mental Retardation Protein and Stem Cells
7:00 - 8:00 PM Social Hour w/ Lite Bites Quandary Peak
7:30 - 10:00 PM Poster Session 1
Registered attendees for this meeting can view Abstracts for this session starting on 02/06/2009 		Quandary Peak
Sunday, March 8
7:00 - 8:00 AM Breakfast Quandary Peak
8:00 - 11:00 AM Autism
Registered attendees for this meeting can view Abstracts for this session starting on 02/06/2009 		Longs Peak
Daniel H. Geschwind, University of California, Los Angeles, USA
Identification of Genomic Loci Involved in Autism
David H. Ledbetter, Emory University School of Medicine, USA
Copy-Number Variants in Autism
* Janine M. LaSalle, University of California, Davis, USA
Epigenetic Etiologies of Autism Spectrum Disorders
Speaker to be Announced,
Short Talk(s) to be Chosen from Abstracts,
Following Session is for Schizophrenia and Bipolar Disorder (X1)
8:00 - 11:00 AM Genes and Pathways
Registered attendees for this meeting can view Abstracts for this session starting on 02/06/2009 		Grays Peak
David Porteous, University of Edinburgh, UK
Genetic and Molecular Investigation of DISC1
Hongjun Song, Johns Hopkins University School of Medicine, USA
DISC1 and Neuronal Development
Daniel R. Weinberger, NIMH/NIH, USA
Genetic and Molecular Studies of NRG1/ErbB4
Speaker to be Announced,
Novel Susceptibility Genes Emerging from Genetic Studies
Short Talk(s) to be Chosen from Abstracts,
9:20 - 9:40 AM Coffee Break Longs Peak Foyer
11:00 AM- 1:00 PM Poster Setup Quandary Peak
11:00 AM- On Own for Lunch
1:00 - 10:00 PM Poster Viewing Quandary Peak
4:30 - 5:00 PM Coffee Available Longs Peak Foyer
5:00 - 7:00 PM Imprinting Disorders
Registered attendees for this meeting can view Abstracts for this session starting on 02/06/2009 		Longs Peak
* Arthur L. Beaudet, Baylor College of Medicine, USA
Molecular Basis of Angelman Syndrome
Laura Herzing, Children's Memorial Research Center, USA
DNA Methylation and Imprinting Disorders
Edwin J. Weeber, University of South Florida, USA
Synaptic Plasticity Defects in Angelman Syndrome
Short Talk to be Chosen from Abstracts,
Following Session is for Schizophrenia and Bipolar Disorder (X1)
5:00 - 7:00 PM Genes and Pathways II
Registered attendees for this meeting can view Abstracts for this session starting on 02/06/2009 		Grays Peak
Marc G. Caron, Duke University Medical Center, USA
Akt/GSKbeta Signaling and Behavioral Abnormalities
Li-Huei Tsai, Massachusetts Institute of Technology, USA
Signaling Pathways Linking Brain Development and Schizophrenia
Speaker to be Announced,
Novel Susceptibility Genes Emerging from Genetic Studies
Short Talk to be Chosen from Abstracts,
7:00 - 8:00 PM Social Hour w/ Lite Bites Quandary Peak
7:30 - 10:00 PM Poster Session 2
Registered attendees for this meeting can view Abstracts for this session starting on 02/06/2009 		Quandary Peak
Monday, March 9
7:00 - 8:00 AM Breakfast Quandary Peak
8:00 - 11:00 AM Psychiatric Epigenetics
Registered attendees for this meeting can view Abstracts for this session starting on 02/06/2009 		Longs Peak
Art Petronis, Centre for Addiction and Mental Health, Canada
Epigenomics of Major Psychosis
Erminio Costa, University of Illinois, Chicago, USA
DNA Methylation in Schizophrenia
Speaker to be Announced,
* Michael Meaney, McGill University, Canada
Maternal Regulation of DNA Methylation and Vulnerability for Psychopathology
Short Talk(s) to be Chosen from Abstracts,
Following Session is for Schizophrenia and Bipolar Disorder (X1)
8:00 - 11:00 AM Evolution and Development of the Brain
Registered attendees for this meeting can view Abstracts for this session starting on 02/06/2009 		Grays Peak
Fred H. Gage, The Salk Institute for Biological Studies, USA
Neurogenesis and Relevance of Non-Coding RNAs
Bruce Lahn, University of Chicago, USA
Fast-Evolving Genes of the Human Brain
Speaker to be Announced,
Judith L. Rapoport, NIMH, USA
Brain Development in Childhood Onset Schizophrenia
Short Talk(s) to be Chosen from Abstracts,
9:20 - 9:40 AM Coffee Break Longs Peak Foyer
11:00 AM- On Own for Lunch
2:30 - 4:30 PM Round Table Discussion
Registered attendees for this meeting can view Abstracts for this session starting on 02/06/2009 		Longs Peak
4:30 - 5:00 PM Coffee Available Longs Peak Foyer
5:00 - 7:00 PM Lessons, Conclusions, and Perspectives
Registered attendees for this meeting can view Abstracts for this session starting on 02/06/2009 		Longs Peak
Peter A. Jones, University of Southern California, USA
Epigenetic Regulation in Cancer
Jeffrey M. Besterman, Methylgene Inc., Canada
Epigenetic Therapy of Neurodegenerative Diseases
Bing Ren, University of California, San Diego, USA
Talk Title to be Determined
Following Session is for Schizophrenia and Bipolar Disorder (X1)
5:00 - 7:00 PM Chemical Biology and Therapeutic Strategies
Registered attendees for this meeting can view Abstracts for this session starting on 02/06/2009 		Grays Peak
John R. Kelsoe, University of California, San Diego, USA
Perspectives in Pharmacogenomics
Christopher P. Austin, National Human Genome Research Institute, USA
Small Molecule Screens in Schizophrenia and Bipolar Disorder
Edward M. Scolnick, MIT Broad Institute, USA
Closing Talk: Towards Mechanism Based Drug Development in Bipolar Disorder and Schizophrenia: Using Genetics and Neurobiology to Drive Novel Screening Methods
7:00 - 8:00 PM Social Hour w/ Lite Bites Quandary Peak
8:00 - 11:00 PM Entertainment Quandary Peak
Tuesday, March 10
Departure
      *=Session Chair     †=Speaker invited, not yet responded.




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Neurodevelopmental disorders are highly heterogeneous constellations of disorders, both in terms of etiology and clinical manifestations. Past effort has focused on identifying the genetic basis of these disorders with minimal success. Epigenetic modulations, mediated by DNA methylation, RNA-associated silencing, and histone modification, can imprint dynamic environmental experiences on the “fixed” genome, resulting in stable alterations in phenotypes. This conference will focus on an emerging area of biomedical research: how epigenetic modulation shapes brain development and disorders. The meeting will examine the common molecular pathways affected in several related neurodevelopmental disorders and discuss how pre- and postnatal exposures to pollutants, alcohol, drug, nutrition, and parental care, etc., may affect neurodevelopment via epigenetic pathways. The overall goal of the meeting is to gain insight into the common molecular pathways affected among these disorders and to discover potential therapeutic targets that have been missed by looking at one disorder at a time.