Keystone Symposia
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LANGUAGE NOTE: This meeting will be conducted in English.
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Meeting Program

To view program in "24 hour" time (international) click here.


Monday, February 15
3:00 - 7:30 PM Registration Longs Peak Foyer
6:30 - 7:30 PM Refreshments Longs Peak Foyer
7:30 - 8:30 PM Keynote Address
Registered attendees for this meeting can view Abstracts for this session starting on 01/15/2010
Grays/Longs Peak
Fiona M. Watt, CRUK Cambridge Research Institute, UK
* Shinya Yamanaka, Kyoto University/Gladstone Institute, Japan
James A. Thomson, Morgridge Institute for Research, University of Wisconsin, USA
Human ES Cells and iPS Cells
Tuesday, February 16
7:00 - 8:00 AM Breakfast Shavano/Torreys
8:00 - 11:15 AM iPS Cells
Registered attendees for this meeting can view Abstracts for this session starting on 01/15/2010
Grays/Longs Peak
* Fiona M. Watt, CRUK Cambridge Research Institute, UK
Shinya Yamanaka, Kyoto University/Gladstone Institute, Japan
Induction of Pluripotency by Defined Factors
Rudolf Jaenisch, Whitehead Institute for Biomedical Research, USA
Molecular Mechanisms of Pluripotency and Reprogramming
Juan Carlos Izpisúa-Belmonte, The Salk Institute, USA
Linking the p53 Tumor Suppressor Pathway to Somatic Cell Reprogramming
Kathrin Plath, University of California, Los Angeles, USA
Mechanisms of Transcription Factor- Induced Reprogramming
Jing Liao, Shanghai Institute of Biochemistry and Cell Biology, China
Short Talk: Generation of Induced Pluripotent Stem Cell Lines from Rat Adult Cells
Christoph Bock, Harvard University, USA
Short Talk: The Epigenome of Pluripotent Cells: Variations of a Common Theme
9:20 - 9:40 AM Coffee Break Longs Peak Foyer
11:15 AM- On Own for Lunch and Recreation
11:15 AM- 1:00 PM Poster Setup Shavano/Torreys
1:00 - 10:00 PM Poster Viewing Shavano/Torreys
4:30 - 5:00 PM Coffee Available Longs Peak Foyer
5:00 - 7:15 PM Pluripotency
Registered attendees for this meeting can view Abstracts for this session starting on 01/15/2010
Grays/Longs Peak
* Shinya Yamanaka, Kyoto University/Gladstone Institute, Japan
Austin G. Smith, University of Cambridge, UK
Intrinsic and Extrinsic Regulation of the Pluripotent Ground State
Ihor R. Lemischka, Mount Sinai School of Medicine, USA
Genome-Wide Analyses of Molecular Mechanisms Underlying Pluripotency
Amanda G. Fisher, Imperial College London, UK
Stem Cells and Epigenetic Reprogramming
Lay Teng Ang, University of Cambridge/Genome Institute of Singapore, UK
Short Talk: MicroRNA Function in Regulating Pluripotency and Differentiation of Human Embryonic Stem Cells
Li-Fang Chu, Baylor College of Medicine, USA
Short Talk: Primordial Germ Cells as the Immediate Precursors of Embryonic Stem Cells
7:15 - 8:15 PM Social Hour w/ Lite Bites Shavano/Torreys
7:30 - 10:00 PM Poster Session 1
Registered attendees for this meeting can view Abstracts for this session starting on 01/15/2010
Shavano/Torreys
Wednesday, February 17
7:00 - 8:00 AM Breakfast Shavano/Torreys
8:00 - 11:30 AM Reprogramming
Registered attendees for this meeting can view Abstracts for this session starting on 01/15/2010
Grays/Longs Peak
* Austin G. Smith, University of Cambridge, UK
M. Azim Surani, University of Cambridge, UK
Resetting the Epigenome during Germ Cell Specification and by LIF-STAT3 Signaling
Hans R. Schöler, Max Planck Institute for Molecular Biomedicine, Germany
Induction of Pluripotency in Adult Somatic and Germline Stem Cells
Kevin C. Eggan, Harvard University, USA
Identification and Characterization of Small Reprogramming Molecules
Chad A. Cowan, Harvard University, USA
Programming and Reprogramming: New Approaches for Understanding Disease
Azadeh Golipour, Samuel Lunenfeld Research Institute, Canada
Short Talk: A Systematic Approach to Identify Novel Regulators of Somatic Cell Reprogramming
Collin A. Melton, University of California, San Francisco, USA
Short Talk: Opposing microRNA Families Regulate Self-Renewal in Mouse Embryonic Stem Cells
Larry Stanton, Genome Institute of Singapore, Singapore
Short Talk: Converting Sox17 into a Pluripotency Reprogramming Factor
9:20 - 9:40 AM Coffee Break Longs Peak Foyer
11:30 AM- On Own for Lunch and Recreation
11:30 AM- 1:00 PM Poster Setup Shavano/Torreys
1:00 - 10:00 PM Poster Viewing Shavano/Torreys
4:30 - 5:00 PM Coffee Available Longs Peak Foyer
5:00 - 7:00 PM Other Pluripotent Stem Cells
Registered attendees for this meeting can view Abstracts for this session starting on 01/15/2010
Grays/Longs Peak
* Hans R. Schöler, Max Planck Institute for Molecular Biomedicine, Germany
Takashi Shinohara, Kyoto University, Japan
Positive and Negative Regulators of Mouse Germline Stem (GS) Cell Proliferation
Helen M. Blau, Stanford University, USA
Reprogramming Towards Pluripotency Requires AID-Dependent DNA Demethylation
Anthony Atala, Wake Forest University, USA
Amniotic Fluid and Placental-Derived Stem Cells
7:00 - 8:00 PM Social Hour w/ Lite Bites Shavano/Torreys
7:30 - 10:00 PM Poster Session 2
Registered attendees for this meeting can view Abstracts for this session starting on 01/15/2010
Shavano/Torreys
Thursday, February 18
7:00 - 8:00 AM Breakfast Shavano/Torreys
8:00 - 11:15 AM Somatic Stem Cells
Registered attendees for this meeting can view Abstracts for this session starting on 01/15/2010
Grays/Longs Peak
* Shinya Yamanaka, Kyoto University/Gladstone Institute, Japan
Fiona M. Watt, CRUK Cambridge Research Institute, UK
Defining the Epidermal Stem Cell Niche
Toshio Suda, Keio University, Japan
Hematopoietic Stem Cells and their Niches
Amy J. Wagers, Harvard University, USA
Regenerative Potential of Skeletal Muscle Stem Cells
Fred H. Gage, The Salk Institute for Biological Studies, USA
Neural Stem Cells and their Fates
Valerie Horsley, Yale University, USA
Short Talk: Extrinsic Regulation of Skin Stem Cells
Tae-Hee Kim, Dana-Farber Cancer Institute, Harvard Medical School, USA
Short Talk: A Role for Notch Signaling in Stomach Epithelial Stem Cell Homeostasis
9:20 - 9:40 AM Coffee Break Longs Peak Foyer
11:15 AM- On Own for Lunch and Recreation
11:15 AM- 1:00 PM Poster Setup Shavano/Torreys
1:00 - 10:00 PM Poster Viewing Shavano/Torreys
4:30 - 5:00 PM Coffee Available Longs Peak Foyer
5:00 - 7:30 PM Differentiation of Stem Cells I
Registered attendees for this meeting can view Abstracts for this session starting on 01/15/2010
Grays/Longs Peak
* Toshio Suda, Keio University, Japan
Shin-Ichi Nishikawa, RIKEN Center for Developmental Biology, Japan
The Pathway of Hematopoietic Stem Cell Development Explained
Deepak Srivastava, Gladstone Institute of Cardiovascular Disease, USA
microRNA Regulation of Cardiac Stem Cell Fate
Hideyuki Okano, Keio University School of Medicine, Japan
Regeneration of the Damaged CNS with iPS Cells
Hans Keirstead, University of California, Irvine, USA
Clinically-Compliant Differentiation of hESCs for the Treatment of Spinal Cord Injury and Disease
Catherin Niemann, University of Cologne, Germany
Short Talk: Important Role of Hair Follicle Stem Cells for Generation and Differentiation of Sebaceous Gland Cells during Skin Homeostasis
7:30 - 8:30 PM Social Hour w/ Lite Bites Shavano/Torreys
7:30 - 10:00 PM Poster Session 3
Registered attendees for this meeting can view Abstracts for this session starting on 01/15/2010
Shavano/Torreys
Friday, February 19
7:00 - 8:00 AM Breakfast Shavano/Torreys
8:00 - 11:00 AM Differentiation of Stem Cells II
Registered attendees for this meeting can view Abstracts for this session starting on 01/15/2010
Grays/Longs Peak
* Deepak Srivastava, Gladstone Institute of Cardiovascular Disease, USA
E. Edward Baetge, Novocell, Inc., USA
Functional Pancreatic Islet Cells from Embryonic Stem Cells
Ronald D. McKay, National Institutes of Health, USA
Neural Differentiation of Stem Cells
Rita R. Perlingeiro, University of Minnesota, USA
From ES Cells to Skeletal Muscle Precursors
Nobuko Uchida, StemCells Inc., USA
Therapeutic Potential of Human Central Nervous System-Stem Cell: Neuroprotection Strategies
Micha Drukker, Stanford University School of Medicine, USA
Short Talk: Prospective Isolation of Four of the Earliest Precursors to Emerge from Human Embryonic Stem Cells
9:20 - 9:40 AM Coffee Break Longs Peak Foyer
11:00 AM- On Own for Lunch and Recreation
4:30 - 5:00 PM Coffee Available Longs Peak Foyer
5:00 - 7:00 PM Application of Stem Cells
Registered attendees for this meeting can view Abstracts for this session starting on 01/15/2010
Grays/Longs Peak
* Ronald D. McKay, National Institutes of Health, USA
Amy Sinor, Harvard Stem Cell Institute, USA
ES Cell-Derived Cells for Disease Mechanism and Drug Discovery
Zhong Zhong, GlaxoSmithKline R&D China, China
Drug Discovery Targeting Neural Stem Cells
Gabriela Gebrin Cezar, University of Wisconsin, USA
Metabolomics of Human Embryonic Stem Cells: Unraveling Biochemical Pathways of Neurodevelopmental Disorders
Karl-Dimiter Bissig, The Salk Institute, USA
Short Talk: Cell Based Therapy for Liver Disease
7:00 - 8:00 PM Social Hour w/ Lite Bites Shavano/Torreys
8:00 - 11:00 PM Entertainment Shavano/Torreys
Saturday, February 20
Departure
      *=Session Chair     †=Speaker invited, not yet responded.



Keystone Symposia would like to thank the sponsors of this meeting for their generous support:

We gratefully acknowledge additional support for this conference from:





GlaxoSmithKline R&D China





The Directors' Fund

These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.

We gratefully acknowledge the generous grant for this conference provided by:

National Institutes of Health
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)

Grant No. 1R13HD063192-01


The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.


We gratefully acknowledge the organizations that provide Keystone Symposia with additional support, such as marketing and advertising...

Click here to view these companies

Recent progress in induced pluripotent stem (iPS) cells has shown that stem cells can be generated from differentiated progenies by introducing just a few defined factors. In addition, various stem cells have been isolated from human tissues. Stem cells from patients will provide various tools in understanding disease mechanisms, searching for effective drugs, and evaluating toxicity of drug candidates. Furthermore, human iPS cells and other stem cells may provide various types of cells for regenerative medicine. In this meeting, we will discuss how stem cells, including iPS cells, are isolated, generated and maintained. We will also provide an update on induction of differentiated cells from stem cells. We then will discuss progress in application of pluripotent stem cells and other stem cells in basic research, drug discovery, toxicology, and regenerative medicine.