Meeting Program
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To view program in "24 hour" time (international) click here. |
| Monday, April 12 | ||
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| 3:00 - 7:30 PM | Registration | Foyer |
| 6:30 - 7:30 PM | Refreshments | Foyer |
| 7:15 - 7:30 PM | Orientation | |
| 7:30 - 9:30 PM |
Keynote Session (Joint) Registered attendees for this meeting can view Abstracts for this session starting on 03/12/2010 |
Sea to Sky Ballroom B,C |
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Victor Ambros,
University of Massachusetts, USA
MicroRNAs in Model Systems and Human Disease |
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Jennifer A. Lippincott-Schwartz,
National Institutes of Health, USA
Mitochondrial Role in Cell Cycle Control and Autophagy |
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| Tuesday, April 13 | ||
| 7:00 - 8:00 AM | Breakfast | Sea to Sky Ballroom A, Lower Level |
| 8:00 - 11:00 AM |
From Stem Cell Development to Transplantation Registered attendees for this meeting can view Abstracts for this session starting on 03/12/2010 |
Sea to Sky Ballroom B |
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Bernhard J. Hering,
University of Minnesota, USA
Islet Transplantation: Today and Tomorrow |
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Anne Grapin-Botton,
Ecole Polytechnique Fédérale De Lausanne, Switzerland
Role of Pancreas 3D Architecture in Endocrine Cell Development |
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Speaker to be Announced,
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Maike Sander,
University of California, San Diego, USA
Control of Cell Fate Choice in the Pancreas |
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| Following Session is for Diabetes (Z6) | ||
| 8:00 - 11:00 AM |
Genetics of Diabetes Registered attendees for this meeting can view Abstracts for this session starting on 03/12/2010 |
Sea to Sky Ballroom C |
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Philippe Froguel,
Imperial College of London, UK
Genome Structure and Point DNA Variation: The Power of the Extreme in Diabesity |
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Mark McCarthy,
University of Oxford, UK
Type 2 Diabetes: Susceptibility Variants across the Allele Frequency Spectrum |
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Jose C. Florez,
Massachusetts General Hospital, USA
Genetic Epidemiology of T2D and Related Traits in General Populations |
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Eric Schadt,
Pacific Biosciences, USA
Multi-Tissue Networks Elucidate T2D Circuits |
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Jussi A. Pihlajamäki,
Kuopio University Hospital, Finland
Short Talk: Alternative Splicing is Regulated by Weight Loss and Differs between Fat Depots in Humans |
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Jeremy B.M. Jowett,
Baker IDI Heart and Diabetes Institute, Australia
Short Talk: Expression Profiling Identifies Biomarkers for Progression to Type 2 Diabetes |
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| 9:20 - 9:40 AM | Coffee Break | Foyer |
| 11:00 AM- | On Own for Lunch and Recreation | |
| 11:00 AM- 1:00 PM | Poster Setup | Foyer/Mountain View/Sea to Sky Ballroom A |
| 1:00 - 10:00 PM | Poster Viewing | Foyer/Mountain View/Sea to Sky Ballroom A |
| 4:30 - 5:00 PM | Coffee Available | Foyer |
| 5:00 - 7:00 PM |
Signaling in Pancreatic B-Cells Registered attendees for this meeting can view Abstracts for this session starting on 03/12/2010 |
Sea to Sky Ballroom B |
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Eckhard Lammert,
Heinrich-Heine-University of Duesseldorf, Germany
Role of Blood Vessels in Pancreatic Islet Development and Function |
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Marc A. Prentki,
CRCHUM/ University of Montreal, Canada
Beta Cell Metabolic Signaling and Dysfunction in Type 2 Diabetes |
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Ingo B. Leibiger,
Karolinska Institutet, Sweden
Insulin Signaling in the Pancreatic Beta Cell |
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| Following Session is for Diabetes (Z6) | ||
| 5:00 - 7:00 PM |
Cell and Tissue Signaling Mechanisms in Diabetes Registered attendees for this meeting can view Abstracts for this session starting on 03/12/2010 |
Sea to Sky Ballroom C |
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Claire Bastie,
Albert Einstein College of Medicine, USA
Fyn-Dependent Regulation of Energy Expenditure and Body Weight is Mediated by Tyrosine Phosphorylation of LKB1 |
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Robert E. Lewis,
University of Nebraska Medical Center, USA
Molecular Scaffolds as Energy Sensors |
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Bei B. Zhang,
Merck Research Laboratories, USA
Modulation of Glucose, Amino Acid and Lipid Metabolism Pathways with Pharmacological Agents |
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Philipp Gut,
University of California San Francisco, USA
Short Talk: In vivo Drug Discovery of New Regulators of Glucose Metabolism using Transgenic “Gluconeogenesis Reporter” Zebrafish |
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| 7:00 - 8:00 PM | Social Hour w/ Lite Bites | Foyer/Mountain View/Sea to Sky Ballroom A |
| 7:30 - 10:00 PM |
Poster Session 1 Registered attendees for this meeting can view Abstracts for this session starting on 03/12/2010 |
Foyer/Mountain View/Sea to Sky Ballroom A |
| Wednesday, April 14 | ||
| 7:00 - 8:00 AM | Breakfast | Sea to Sky Ballroom A, Lower Level |
| 8:00 - 11:00 AM |
Transcriptional Networks Signaling Registered attendees for this meeting can view Abstracts for this session starting on 03/12/2010 |
Sea to Sky Ballroom B |
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Doris A. Stoffers,
Institute for Diabetes, Obesity and Metabolism, University of Pennsylvania, USA
Pdx1 Partners and Targets in Beta Cell Development and Function |
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Markus Stoffel,
Institut f. Molekulare Systembiologie, Switzerland
MicroRNA Networks |
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Wilhelm Krek,
ETH Zurich, Switzerland
HIF Signaling in Beta Cells |
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Alan D. Attie,
University of Wisconsin-Madison, USA
Networks of QTLs, mRNAs, and microRNAs in Beta Cell Growth and Function |
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Short Talk(s) to be Chosen from Abstracts,
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| Following Session is for Diabetes (Z6) | ||
| 8:00 - 11:00 AM |
Intertissue Communication Registered attendees for this meeting can view Abstracts for this session starting on 03/12/2010 |
Sea to Sky Ballroom C |
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Barbara B. Kahn,
Beth Israel Deaconess Medical Center, USA
A Novel Pathway in Adipose Tissue and Liver that Regulates Adiposity |
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Kenneth Walsh,
Boston University School of Medicine, USA
Discovery of Novel Myokines |
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Philipp E. Scherer,
University of Texas Southwestern Medical Center, USA
Discovery of Novel Adipokines |
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Fatima Bosch,
Universitat Autonoma Barcelona, Spain
Gene Therapy and Diabetes |
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David B. Briggs,
University of Arizona, USA
Short Talk: Inhibition of Adiponectin Oligomerization under Oxidizing Conditions and Induction of an Oxidizing Redox Environment in Endoplasmic Reticulum of 3T3-L1 Adipocytes Exposed to High Concentrations of Palmitate |
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Marianna Sadagurski,
Childrens Hospital, Harvard Medical School, USA
Short Talk: Inactivation of Foxo1 in Leptin Receptor (LepRb)-Expressing Neurons Reverses Obesity and Diabetes, Caused by Deletion of Insulin Receptor Substrate 2 (Irs2) |
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| 9:20 - 9:40 AM | Coffee Break | Foyer |
| 11:00 AM- | On Own for Lunch and Recreation | |
| 11:00 AM- 1:00 PM | Poster Setup | Foyer/Mountain View/Sea to Sky Ballroom A |
| 1:00 - 10:00 PM | Poster Viewing | Foyer/Mountain View/Sea to Sky Ballroom A |
| 4:30 - 5:00 PM | Coffee Available | Foyer |
| 5:00 - 7:00 PM |
Molecular Mechanisms in Insulin Secretion and Action (Joint) Registered attendees for this meeting can view Abstracts for this session starting on 03/12/2010 |
Sea to Sky Ballroom B,C |
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C. Ronald Kahn,
Joslin Diabetes Center, USA
Insulin Signaling and Insulin Resistance: The Ultimate Systems Biology Problem |
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Per-Olof Berggren,
Karolinska Institutet, Sweden
Systems Biology Approach to Study Beta Cell Function and Survival |
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Morris J. Birnbaum,
University of Pennsylvania, USA
The Role of Akt in the Regulation of Hepatic Metabolism by Insulin |
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Short Talk to be Chosen from Abstracts,
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| 7:00 - 8:00 PM | Social Hour w/ Lite Bites | Foyer/Mountain View/Sea to Sky Ballroom A |
| 7:30 - 10:00 PM |
Poster Session 2 Registered attendees for this meeting can view Abstracts for this session starting on 03/12/2010 |
Foyer/Mountain View/Sea to Sky Ballroom A |
| Thursday, April 15 | ||
| 7:00 - 11:00 AM | Poster Setup | Foyer/Mountain View/Sea to Sky Ballroom A |
| 7:00 - 8:00 AM | Breakfast | Sea to Sky Ballroom A, Lower Level |
| 8:00 - 11:00 AM |
Control of Insulin Secretory Machinery in Diabetes Registered attendees for this meeting can view Abstracts for this session starting on 03/12/2010 |
Sea to Sky Ballroom B |
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Patrik Rorsman,
Oxford Centre for Diabetes, Endocrinology and Metabolism, UK
Calcium Channels and Insulin Exocytosis |
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Michele Solimena,
Dresden University of Technology, Germany
Signaling from the Insulin Granule to the Nucleus |
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Gerard Karsenty,
Columbia University Medical Center, USA
Regulation of Glucose Homeostasis by Osteocalcin |
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Herbert Y. Gaisano,
University of Toronto, Canada
Molecular Mechanism of Insulin Granule-Granule Fusion Contributing to Biphasic Insulin Secretion |
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| Following Session is for Diabetes (Z6) | ||
| 8:00 - 11:00 AM |
Inflammatory Mechanisms and Insulin Resistance Registered attendees for this meeting can view Abstracts for this session starting on 03/12/2010 |
Sea to Sky Ballroom C |
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Diane J. Mathis,
Harvard Medical School, USA
Lymphocyte Regulation of Adipose Tissue Inflammation |
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Roger J. Davis,
University of Massachusetts Medical School, USA
Pathogenesis Mechanisms of the JNK Pathway |
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Remy G. Burcelin,
Institute of Molecular Medicine, France
Intestinal Microflora, Inflammation, and Metabolic Diseases |
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Michael P. Czech,
University of Massachusetts Medical School, USA
RNAi-Based Strategies to Address Metabolic Dysfunction |
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Birgitte Lindegaard,
Centre of Inflammation and Metabolism, Rigshospitalet, Denmark
Short Talk: IL-18 Increases Intramuscular Fat Oxidation by Activating AMPK |
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Heather C. Denroche,
University of British Columbia, Canada
Short Talk: Leptin Therapy Reverses Fasting Hyperglycemia and Enhances Insulin Sensitivity in Diabetic Mice, Independent of Hepatic Leptin Signalling |
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| 9:20 - 9:40 AM | Coffee Break | Foyer |
| 11:30 AM- 12:30 PM | Lunch | |
| 12:30 - 2:30 PM |
Poster Session 3 Registered attendees for this meeting can view Abstracts for this session starting on 03/12/2010 |
Foyer/Mountain View/Sea to Sky Ballroom A |
| 4:30 - 5:00 PM | Coffee Available | Foyer |
| 5:00 - 7:00 PM |
Emerging Targets for Improving Insulin Action and Secretion (Joint) Registered attendees for this meeting can view Abstracts for this session starting on 03/12/2010 |
Sea to Sky Ballroom B,C |
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Richard D. Dimarchi,
Indiana University, USA
Novel Glucagon-Like Chimera Peptides – Virtues of Combinatorial Pharmacology |
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David E. Moller,
Eli Lilly and Company, USA
Challenges and Opportunities for Diabetes Drug Discovery |
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Johan Auwerx,
Ecole Polytechnique Federale de Lausanne, Switzerland
Integrating Metabolic Control by NAD+ Sensors |
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| 7:00 PM- | On Own for Dinner | Foyer/Mountain View/Sea to Sky Ballroom A |
| Friday, April 16 | ||
| 7:00 - 8:00 AM | Breakfast | Sea to Sky Ballroom A, Lower Level |
| 8:00 - 11:00 AM |
Insulin Secretion and Action in Humans (Joint) Registered attendees for this meeting can view Abstracts for this session starting on 03/12/2010 |
Sea to Sky Ballroom B,C |
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Andrew Hattersley,
Peninsula Medical School, UK
Learning from Genetic Beta Cell Defects in Man |
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Anna Moore,
Massachusetts General Hospital, USA
Imaging Pancreatic Islets in vivo: Current Status |
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Juleen R. Zierath,
Karolinska Institutet, Sweden
Insulin Action in Human Skeletal Muscle |
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Peter Arner,
Karolinska Institute, Sweden
Dysfunction in Human Adipose Tissue and Insulin Resistance |
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Short Talk(s) to be Chosen from Abstracts,
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| 9:20 - 9:40 AM | Coffee Break | Foyer |
| 11:00 AM- | On Own for Lunch and Recreation | |
| 4:30 - 5:00 PM | Coffee Available | Foyer |
| 5:00 - 7:00 PM |
Beta Cell Stress in Diabetes Registered attendees for this meeting can view Abstracts for this session starting on 03/12/2010 |
Sea to Sky Ballroom B |
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Marc Y. Donath,
Universitätsspital Zürich, Universität Zürich, Switzerland
Islet Inflammation in Type 2 Diabetes: Novel Mechanisms and Treatment |
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Thomas Mandrup-Poulsen,
Hagedorn Research Institute, Denmark
Cytokine Signaling in Inflammatory beta-Cell Destruction |
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Rohit N. Kulkarni,
Joslin Diabetes Center, USA
Insulin/IGF-I Signaling, Mitochondrial Function and Endoplasmic Stress in Pancreatic beta-Cells |
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Short Talk to be Chosen from Abstracts,
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| Following Session is for Diabetes (Z6) | ||
| 5:00 - 7:00 PM |
Type 2 Diabetes in Children and Adolescents Registered attendees for this meeting can view Abstracts for this session starting on 03/12/2010 |
Sea to Sky Ballroom C |
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Rebecca Anne Simmons,
University Pennsylvania School of Medicine, USA
Epigenetic Mechanisms in the Development of Type 2 Diabetes |
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Susan Ozanne,
University of Cambridge, UK
Early Life Programming of Type 2 Diabetes |
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Phil Zeitler,
University of Colorado Denver, USA
Type 2 Diabetes in Children and Adolescents: Epidemiology, Pathophysiology, and Comorbidities |
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Kasper Rud†,
Faculty of Health Sciences, Denmark
Short Talk: Effects of Gestational Low Protein Diet Followed by Postnatal High Fat or High Sucrose Diet on the Interplay between Fat and Carbohydrate Metabolism in Rat Mitochondria |
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| 7:00 - 8:00 PM | Social Hour w/ Lite Bites | Foyer/Mountain View/Sea to Sky Ballroom A |
| 8:00 - 11:00 PM | Entertainment | Foyer/Mountain View/Sea to Sky Ballroom A |
| Saturday, April 17 | ||
| Departure | ||
| *=Session Chair †=Speaker invited, not yet responded. | ||
Keystone Symposia would like to thank the sponsors of this meeting for their generous support:
We gratefully acknowledge additional support for this conference from:
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These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.
Click here to view all of the donors who support the Directors' Fund.
We gratefully acknowledge the generous grants for this conference provided by:
National Institutes of Health
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
National Institute on Aging (NIA)
Grant No. 1R13DK084688-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We gratefully acknowledge the organizations that provide Keystone Symposia with additional support, such as marketing and advertising...
Click here to view these companies