Keystone Symposia
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LANGUAGE NOTE: This meeting will be conducted in English.
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Meeting Program

To view program in "24 hour" time (international) click here.


Sunday, March 27
3:00 - 7:30 PM Registration Lower Atrium
6:30 - 7:30 PM Refreshments Lower Atrium
7:30 - 8:30 PM Keynote Address
Registered attendees for this meeting can view Abstracts for this session starting on 02/27/2011
Gallatin
Irving L. Weissman, Stanford University, USA
Biology of Hematopoietic Stem and Progenitor Cells
Monday, March 28
7:00 - 8:00 AM Breakfast Jefferson/Madison
8:00 - 11:00 AM Developmental Hematopoiesis
Registered attendees for this meeting can view Abstracts for this session starting on 02/27/2011
Gallatin
Utpal Banerjee, University of California, Los Angeles, USA
Development of Blood Cells in the Fly
David Traver, University of California, San Diego, USA
Development of Vertebrate Hematopoetic Stem Cells
Hanna K. A. Mikkola, University of California, Los Angeles, USA
Mechanisms Regulating Hematopoietic Stem Cell Development
Nancy A. Speck, University of Pennsylvania, USA
Runx1 Function in the Generation of Hemogenic Endothelium
9:20 - 9:40 AM Coffee Break Lower Atrium
11:00 AM- 1:00 PM Poster Setup Jefferson/Madison
1:00 - 10:00 PM Poster Viewing Jefferson/Madison
2:30 - 4:30 PM Workshop 1: Hemogenic Endothelium. Sponsored by BD Biosciences.
Gallatin
* Thierry Jaffredo, UPMC, CNRS UMR7622, France
Short Talks to be Chosen from Abstracts, ,
4:30 - 5:00 PM Coffee Available Lower Atrium
5:00 - 7:00 PM Adult Hematopoietic Stem and Progenitor Cells
Registered attendees for this meeting can view Abstracts for this session starting on 02/27/2011
Gallatin
Leonard I. Zon, Children's Hospital, Boston, USA
From Fish to Bedside: The Zebrafish as a Model for Drug Discovery
Hiromitsu Nakauchi, Institute of Medical Science, University of Tokyo, Japan
Control of Hematopoietic Stem Cell Hibernation by the Bone Marrow Niche
Emmanuelle Passegué, University of California, San Francisco, USA
Molecular and Cellular Understanding of Normal and Malignant Hematopoiesis
Short Talk to be Chosen from Abstracts,
7:00 - 8:00 PM Social Hour w/ Lite Bites Jefferson/Madison
7:30 - 10:00 PM Poster Session 1
Registered attendees for this meeting can view Abstracts for this session starting on 02/27/2011
Jefferson/Madison
Tuesday, March 29
7:00 - 8:00 AM Breakfast Jefferson/Madison
8:00 - 11:00 AM Myelopoiesis
Registered attendees for this meeting can view Abstracts for this session starting on 02/27/2011
Gallatin
James Palis, University of Rochester, USA
Ontogeny of Erythropoiesis in the Mammalian Embryo
Constanze Bonifer, St. James University, UK
Molecular Dissection of Gene Activation Processes in the Hematopoietic System Using ES Cell Differentiation as Model
Daniel G. Tenen, Center for Life Science, USA
Myeloid Transcriptional Factors in Stem Cell Lineage Commitment and Leukemia
Margaret A. Goodell, Baylor College of Medicine, USA
Stress Regulation of Hematopoietic Stem Cells
Short Talk(s) to be Chosen from Abstracts,
9:20 - 9:40 AM Coffee Break Lower Atrium
11:00 AM- 1:00 PM Poster Setup Jefferson/Madison
1:00 - 10:00 PM Poster Viewing Jefferson/Madison
4:30 - 5:00 PM Coffee Available Lower Atrium
5:00 - 7:00 PM Lymphopoiesis
Registered attendees for this meeting can view Abstracts for this session starting on 02/27/2011
Gallatin
Jason G. Cyster, University of California, San Francisco, USA
Control of Lymphoid Development by Chemokines
Meinrad Busslinger, Research Institute of Molecular Pathology, Austria
Transcriptional Control of B Cell Development
Stephen M. Hedrick, University of California, San Diego, USA
FOXO Factors Control Development and Homeostasis of T Lymphocytes
Short Talk to be Chosen from Abstracts,
7:00 - 8:00 PM Social Hour w/ Lite Bites Jefferson/Madison
7:30 - 10:00 PM Poster Session 2
Registered attendees for this meeting can view Abstracts for this session starting on 02/27/2011
Jefferson/Madison
Wednesday, March 30
7:00 - 8:00 AM Breakfast Jefferson/Madison
8:00 - 11:00 AM The Microenvironmental Niche
Registered attendees for this meeting can view Abstracts for this session starting on 02/27/2011
Gallatin
Amy J. Wagers, Harvard University, USA
Role of the Niche in Hematopoietic Stem Cell Self-Renewal, Aging and Malignancy
David T. Scadden, MGH/Harvard University, USA
Hematopoietic Stem Cell Niche as an Inducer of Hematopoietic Disease
Timm Schroeder, Helmholtz Center Munich, Germany
In vitro Imaging of the Mammalian Hematopoietic Niche
Paul S. Frenette, Mount Sinai School of Medicine, USA
Circadian Control of Hematopoiesis
9:20 - 9:40 AM Coffee Break Lower Atrium
11:00 AM- 1:00 PM Poster Setup Jefferson/Madison
1:00 - 10:00 PM Poster Viewing Jefferson/Madison
2:30 - 4:30 PM Workshop 2: The Leukemic Niche. Sponsored by BD Biosciences.
Gallatin
* Rick Van Etten, Tufts Medical Center, USA
Short Talks to be Chosen from Abstracts, ,
4:30 - 5:00 PM Coffee Available Lower Atrium
5:00 - 7:00 PM Systems Approaches to Hematopoiesis
Registered attendees for this meeting can view Abstracts for this session starting on 02/27/2011
Gallatin
Ihor R. Lemischka, Mount Sinai School of Medicine, USA
Network Models of Stem Cell Fate
Trista E. North, Beth Israel Deaconess Medical Center, USA
Talk Title to be Determined
Short Talks to be Chosen from Abstracts, ,
7:00 - 8:00 PM Social Hour w/ Lite Bites Jefferson/Madison
7:30 - 10:00 PM Poster Session 3
Registered attendees for this meeting can view Abstracts for this session starting on 02/27/2011
Jefferson/Madison
Thursday, March 31
7:00 - 8:00 AM Breakfast Jefferson/Madison
8:00 - 11:00 AM Leukomogenesis
Registered attendees for this meeting can view Abstracts for this session starting on 02/27/2011
Gallatin
Craig T. Jordan, University of Rochester School of Medicine and Dentistry, USA
Mechanisms Controlling the Survival of Human Leukemia Stem Cells
James R. Downing, St. Jude Children's Research Hospital, USA
Genetic Alterations in Myeloid Leukemia
Iannis Aifantis, HHMI/New York University School of Medicine, USA
Controlling Hematopoiesis, One Ubiquitin Ligase at a Time
Andreas Trumpp, German Cancer Research Center (DKFZ), Germany
Dormancy in Stem Cells
Short Talk(s) to be Chosen from Abstracts,
9:20 - 9:40 AM Coffee Break Lower Atrium
4:30 - 5:00 PM Coffee Available Lower Atrium
5:00 - 7:00 PM Aging of the Blood System
Registered attendees for this meeting can view Abstracts for this session starting on 02/27/2011
Gallatin
Sean J. Morrison, HHMI/University of Michigan, USA
Aging-Related Changes to Hematopoietic Stem Cells
Gary Van Zant, University of Kentucky College of Medicine, USA
Genetic Mapping of Aging Loci in Hematopoietic Stem Cells
Alan D. D'Andrea, Dana-Farber Cancer Institute, USA
Fanconi Proteins and Aging
Short Talk to be Chosen from Abstracts,
7:00 - 8:00 PM Social Hour w/ Lite Bites Jefferson/Madison
8:00 - 11:00 PM Entertainment Jefferson/Madison
Friday, April 1
Departure
      *=Session Chair     †=Speaker invited, not yet responded.



We gratefully acknowledge support for this conference from:

BD Biosciences





We gratefully acknowledge the organizations that provide Keystone Symposia with additional support, such as marketing and advertising...

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As a paradigmatic model of developmental and regenerative biology, studies of the hematopoietic system have been critical in establishing fundamental principles in growth factor signaling, transcriptional regulation, organ patterning and stem cell biology. Yet, despite many recent ground-breaking discoveries in this field, the last Keystone Symposium on Hematopoiesis was held nearly 5 years ago, in 2004. Now, with new and emerging knowledge, we are beginning to develop a true molecular understanding of the mechanisms by which blood cells are created and maintained, and how their function may be perturbed in the context of hematopoietic deficiency and malignancy. In addition, sophisticated embryological studies have finally documented the existence of bipotential hemogenic endothelium in developing organisms, and striking technological advances in in vivo imaging and cell identification strategies have provided our first direct visualization of blood cell formation in situ, and indicated the key importance of cell migration and interaction with discrete niches in the direction of cell fate and function. Finally, when turned to the study of blood diseases, these tools have provided unexpected insights into the microenvironmental controls that regulate hematopoietic (dys)function during aging and malignancy. In light of these exciting developments, it is clear that the time has come to again bring together hematopoiesis researchers to facilitate and accelerate the exchange of new knowledge and ideas. Our proposed meeting will include a diverse group of scientists studying hematopoiesis with new technologies and complementary model systems. Speakers will be invited from all career stages, and talks will focus on current findings, emerging opportunities, and immediate challenges within the field. We expect this meeting to serve as a catalyst to develop new ideas and collaborations, and to enhance and encourage the creative and interactive science that will continue to push forward discoveries in this important area of research.