Keystone Symposia
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LANGUAGE NOTE: This meeting will be conducted in English.
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Meeting Program

To view program in "24 hour" time (international) click here.


Saturday, January 8
3:00 - 7:30 PM Registration Lower Atrium
6:30 - 7:30 PM Refreshments Lower Atrium
7:30 - 9:30 PM Keynote Session
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010
Gallatin
Juli Feigon, University of California, Los Angeles, USA
RNA Structure and Dynamics
Gerhard Wagner, Harvard Medical School, USA
NMR for Elucidating Biological Mechanisms
Sunday, January 9
7:00 - 8:00 AM Breakfast Jefferson/Madison
8:00 - 11:00 AM New Methods for Studying Structure and Dynamics I
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010
Gallatin
Robert G. Griffin, Massachusetts Institute of Technology, USA
Development and Applications of DNP in Solid State NMR
Christopher P. Jaroniec, Ohio State University, USA
Paramagnetic Reagents for Protein Structure Determination by Solid State NMR
Lewis E. Kay, University of Toronto, Canada
New NMR Methods for Studies of Very Large Proteins
Marcellus Ubbink, Leiden University, Netherlands
Paramagnetic Probes for Studying Macromolecular Structure and Interactions
Short Talk(s) to be Chosen from Abstracts,
9:20 - 9:40 AM Coffee Break Lower Atrium
11:00 AM- 1:00 PM Poster Setup Jefferson/Madison
1:00 - 10:00 PM Poster Viewing Jefferson/Madison
4:30 - 5:00 PM Coffee Available Lower Atrium
5:00 - 7:00 PM Exciting New Results
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010
Gallatin
Sharon L. Campbell, University of North Carolina, Chapel Hill, USA
The Vinculin/F-actin Complex and Regulation by Phosphorylation
Speakers to be Announced,
Short Talk to be Chosen from Abstracts,
7:00 - 8:00 PM Social Hour w/ Lite Bites Jefferson/Madison
7:30 - 10:00 PM Poster Session 1
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010
Jefferson/Madison
Monday, January 10
7:00 - 8:00 AM Breakfast Jefferson/Madison
8:00 - 11:00 AM New Insights into RNA Structure and Dynamics
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010
Gallatin
Frederic H.T. Allain, ETH Zurich, Switzerland
Protein-RNA Recognition: Structures and Dynamics
Victoria Manuel D'Souza, Harvard University, USA
RNA Equilibrium that Regulates Read-Through
Hashim M. Al-Hashimi, University of Michigan, USA
RNA Dynamics and Folding
Michael F. Summers, University of Maryland Baltimore County and HHMI, USA
Structure of the 156 nucleotide HIV-1 RNA Packaging Signal
Short Talk(s) to be Chosen from Abstracts,
9:20 - 9:40 AM Coffee Break Lower Atrium
11:00 AM- 1:00 PM Poster Setup Jefferson/Madison
1:00 - 10:00 PM Poster Viewing Jefferson/Madison
2:30 - 4:30 PM Workshop 1: Advances in Protein and RNA Labeling
Gallatin
Jonathan M. Brown†, ProSpect Pharma, Inc., USA
Talk Title to be Determined
Kwaku Dayie†, University of Maryland, USA
Talk Title to be Determined
James R. Williamson, The Scripps Research Institute, USA
Methods for Selective Isotope Labeling of RNA
Bernhard H. Geierstanger†, Genomics Institute of the Novartis Research Foundation, USA
Talk Title to be Determined
Short Talk to be Chosen from Abstracts,
4:30 - 5:00 PM Coffee Available Lower Atrium
5:00 - 7:00 PM Protein Folding and Function
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010
Gallatin
Peter E. Wright, The Scripps Research Institute, USA
Function and Properties of Intrinsically Unfolded Proteins
Roberto De Guzman, University of Kansas, USA
Structure and Assembly of Bacterial Needles
David E. Wemmer, University of California, Berkeley, USA
Application of NMR and Molecular Simulations to A-beta
7:00 - 8:00 PM Social Hour w/ Lite Bites Jefferson/Madison
7:30 - 10:00 PM Poster Session 2
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010
Jefferson/Madison
Tuesday, January 11
7:00 - 8:00 AM Breakfast Jefferson/Madison
8:00 - 11:00 AM Interactions at Membranes
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010
Gallatin
Tatiana G. Kutateladze, University of Colorado Health Sciences Center, USA
Structural Insight into the ‘Histone Code’ Recognition by PHD Fingers
Katherine A. Henzler-Wildman, Washington University, USA
Mechanistic Studies of Drug Transporter Systems
Charles R. Sanders, Vanderbilt University School of Medicine, USA
Structural Basis for Modulation of Voltage-Gated Potassium Channels by KCNE Family Membrane Proteins
Francesca M. Marassi, Burnham Institute, USA
Structural Studies of Membrane Proteins in Phospholipid Bilayers
Short Talk(s) to be Chosen from Abstracts,
9:20 - 9:40 AM Coffee Break Lower Atrium
11:00 AM- 1:00 PM Poster Setup Jefferson/Madison
1:00 - 10:00 PM Poster Viewing Jefferson/Madison
4:30 - 5:00 PM Coffee Available Lower Atrium
5:00 - 7:00 PM Drug Targets
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010
Gallatin
David J. Weber, University of Maryland, USA
S100 Protein Dynamics and Implications for Drug Design
Wolfgang S. Peti, Brown University, USA
Structural Biology of Large Intracellular Signaling Complexes
Speaker to be Announced,
Short Talk to be Chosen from Abstracts,
7:00 - 8:00 PM Social Hour w/ Lite Bites Jefferson/Madison
7:30 - 10:00 PM Poster Session 3
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010
Jefferson/Madison
Wednesday, January 12
7:00 - 8:00 AM Breakfast Jefferson/Madison
8:00 - 11:00 AM Macromolecular Interactions
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010
Gallatin
Kurt Wüthrich, ETH Zurich/The Scripps Research Institute, Switzerland
Structure-Function Studies of GroEL-GroES
Kylie J. Walters, University of Minnesota, USA
Mechanistic Insights into Ubiquitin-Dependent Proteolysis
Tatyana Igumenova, Texas A&M University, USA
Structure and Dynamics of Lipid-Binding Proteins by NMR
Mitsuhiko Ikura, Ontario Cancer Institute, Canada
Role of NMR in Cancer Cell Signaling Studies
Short Talk(s) to be Chosen from Abstracts,
9:20 - 9:40 AM Coffee Break Lower Atrium
2:30 - 4:30 PM Workshop 2: Computational Approaches for Structure Determination
Gallatin
4:30 - 5:00 PM Coffee Available Lower Atrium
5:00 - 7:00 PM New Methods for Studying Structure and Dynamics II
Registered attendees for this meeting can view Abstracts for this session starting on 12/08/2010
Gallatin
Marc Baldus, Utrecht University, Netherlands
Advances and Frontiers in Solid State NMR
Dorothee Kern, Brandeis University, USA
Understanding Function from Dynamics
Short Talk to be Chosen from Abstracts,
Ad Bax, NIDDK, National Institutes of Health, USA
Advances and Frontiers in Solution-State NMR
7:00 - 8:00 PM Social Hour w/ Lite Bites Jefferson/Madison
8:00 - 11:00 PM Entertainment Jefferson/Madison
Thursday, January 13
Departure
      *=Session Chair     †=Speaker invited, not yet responded.



We gratefully acknowledge support for this conference from:




New Era Enterprises, Inc.



We gratefully acknowledge the generous grant for this conference provided by:

National Institutes of Health
National Institute of General Medical Sciences (NIGMS)

Grant No. 1R13GM095021-01


The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.


We gratefully acknowledge the organizations that provide Keystone Symposia with additional support, such as marketing and advertising...

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Nuclear magnetic resonance (NMR) spectroscopy is now a well-established tool for determining structures of small to moderate size biomacromolecules. The horizon is expanding, however, through recent methodological advances, including the evolution of approaches that combine NMR with computational, X-ray crystallographic, cryo-electron microscopic, and single molecule methodologies. These have led to unprecedented insights into structure, dynamics, and mechanisms, even in large systems, making NMR a premier tool for studying macromolecular function. This symposium will highlight the latest technological advances in NMR spectroscopy, as well as recent bio-functional discoveries made using these approaches. Emphasis will be placed on systems that challenge the current technology, including high-molecular weights, membrane proteins, folding and dynamics, transient states, and drug discovery. In addition, the symposium will provide a forum for discussions on the needs and efforts to consolidate the best approaches, and on the latest advances and new trends in biological NMR.