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LANGUAGE NOTE: This meeting will be conducted in English.
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Meeting Program

To view program in "24 hour" time (international) click here.


Sunday, January 23
3:00 - 7:30 PM Registration Chamisa Lobby
7:30 - 9:30 PM Keynote Session
Registered attendees for this meeting can view Abstracts for this session starting on 12/23/2010
Chamisa Ballroom 1
Brian K. Kobilka, Stanford University, USA
Structure and Function of beta Adrenergic Receptors
Francisco Bezanilla, University of Chicago, USA
From Conductance to Structure
Monday, January 24
7:00 - 8:00 AM Breakfast Los Vaqueros
8:00 - 11:00 AM GPCR Structure and Intramolecular Signal Transduction
Registered attendees for this meeting can view Abstracts for this session starting on 12/23/2010
Chamisa Ballroom 1
Speaker to be Announced,
Fiona Hamilton Marshall, Heptares Therapeutics Ltd, UK
Stabilization of GPCRs for Structural Studies
Steven O. Smith, Stony Brook University, USA
Activation of Rhodopsin: Insights from Solid-State NMR Spectroscopy
Jean-Philippe Pin, Institute of Functional Genomics - CNRS/INSERM/Montpellier University 1&2, France
Intramolecular Signal Transduction in Class C GPCRs
Short Talk(s) to be Chosen from Abstracts,
9:20 - 9:40 AM Coffee Break Chamisa Lobby
11:00 AM- 1:00 PM Poster Setup Chamisa Ballroom 2
1:00 - 10:00 PM Poster Viewing Chamisa Ballroom 2
4:00 - 4:30 PM Data Blitz Session 1
Short Talks to be Chosen from Abstracts, ,
4:30 - 5:00 PM Coffee Available Chamisa Lobby
5:00 - 7:00 PM Interaction of GPCRs with Signaling Proteins and Ligands
Registered attendees for this meeting can view Abstracts for this session starting on 12/23/2010
Chamisa Ballroom 1
Oliver P. Ernst, CharitéCenter, Universitätsmedizin Berlin, Germany
Receptor/G Protein Interaction
Vsevolod V. Gurevich, Vanderbilt University, USA
Receptor/Arrestin Interaction
Speaker to be Announced,
Short Talk to be Chosen from Abstracts,
7:00 - 8:00 PM Social Hour w/ Lite Bites Chamisa Ballroom 2
7:30 - 10:00 PM Poster Session 1
Registered attendees for this meeting can view Abstracts for this session starting on 12/23/2010
Chamisa Ballroom 2
Tuesday, January 25
7:00 - 8:00 AM Breakfast Los Vaqueros
8:00 - 11:00 AM Signal Transduction by Microbial Rhodopsins
Registered attendees for this meeting can view Abstracts for this session starting on 12/23/2010
Chamisa Ballroom 1
Martin Engelhard, Max Planck Institute for Molecular Physiology, Germany
Functional and Structural Studies on Microbial Rhodopsins
Hideki Kandori, Nagoya Institute of Technology, Japan
Active Internal Waters in Archael Rhodopsins
Peter Hegemann, Humboldt-Universität zu Berlin, Germany
Channelrhodopsin: The Light-Gating Problem
Karl Deisseroth, Stanford University, USA
Retinal Proteins as Neural State Switches
Short Talk(s) to be Chosen from Abstracts,
9:20 - 9:40 AM Coffee Break Chamisa Lobby
11:00 AM- 1:00 PM Poster Setup Chamisa Ballroom 2
1:00 - 10:00 PM Poster Viewing Chamisa Ballroom 2
4:00 - 4:30 PM Data Blitz Session 2
Short Talks to be Chosen from Abstracts, ,
4:30 - 5:00 PM Coffee Available Chamisa Lobby
5:00 - 7:00 PM Role of Lipids in Transmembrane Signaling
Registered attendees for this meeting can view Abstracts for this session starting on 12/23/2010
Chamisa Ballroom 1
Roger Sunahara, University of Michigan Medical School, USA
Pharmacology of Single GPCRs in Lipoprotein Particles
Speaker to be Announced,
Poul Nissen, Aarhus University, Denmark
The Cation Pumps and their Interactions with Membranes
7:00 - 8:00 PM Social Hour w/ Lite Bites Chamisa Ballroom 2
7:30 - 10:00 PM Poster Session 2
Registered attendees for this meeting can view Abstracts for this session starting on 12/23/2010
Chamisa Ballroom 2
Wednesday, January 26
7:00 - 8:00 AM Breakfast Los Vaqueros
8:00 - 11:00 AM Novel Approaches
Registered attendees for this meeting can view Abstracts for this session starting on 12/23/2010
Chamisa Ballroom 1
Thomas P. Sakmar, Rockefeller University, USA
Non-Conventional Site-Directed Labeling
Krzysztof Palczewski, Case Western Reserve University, USA
Insight into Receptor Conformations by Radiolytic Footprinting
Marc Baldus, Utrecht University, Netherlands
Approaches to Study Channel Function by NMR
Helmut Grubmüller, Max Planck Institute for Biophysical Chemistry, Germany
Forces and Non-Equilibrium-Dynamics in Systems-Biomolecular Nanomachines
9:20 - 9:40 AM Coffee Break Chamisa Lobby
11:00 AM- 1:00 PM Poster Setup Chamisa Ballroom 2
1:00 - 10:00 PM Poster Viewing Chamisa Ballroom 2
4:00 - 4:30 PM Data Blitz Session 3
Short Talks to be Chosen from Abstracts, ,
4:30 - 5:00 PM Coffee Available Chamisa Lobby
5:00 - 7:00 PM Late-Breaking News
Registered attendees for this meeting can view Abstracts for this session starting on 12/23/2010
Chamisa Ballroom 1
Speakers to be Announced,
7:00 - 8:00 PM Social Hour w/ Lite Bites Chamisa Ballroom 2
7:30 - 10:00 PM Poster Session 3
Registered attendees for this meeting can view Abstracts for this session starting on 12/23/2010
Chamisa Ballroom 2
Thursday, January 27
7:00 - 8:00 AM Breakfast Los Vaqueros
8:00 - 11:00 AM Ion Channel Structure and Function
Registered attendees for this meeting can view Abstracts for this session starting on 12/23/2010
Chamisa Ballroom 1
Leslie B. Vosshall, Rockefeller University, USA
Insect Olfactory Receptors are Heterodimeric-Ligand-Gated Ion Channels
Uhtaek Oh, Seoul National University, South Korea
Anoctamin 1, A Cloned Calcium-Activated Chloride Channel and its Physiological Implications
U. Benjamin Kaupp, Center of Advanced European Studies and Research, Germany
Novel Cyclic Nucleotide-Gated Channels
Crina Nimigean, Weill Cornell Medical College, USA
pH Sensing in KcsA Potassium Channels
Short Talk(s) to be Chosen from Abstracts,
9:20 - 9:40 AM Coffee Break Chamisa Lobby
4:30 - 5:00 PM Coffee Available Chamisa Lobby
5:00 - 7:00 PM Mechanisms of Channels and Transporters
Registered attendees for this meeting can view Abstracts for this session starting on 12/23/2010
Chamisa Ballroom 1
Pierre-Jean Corringer, Institut Pasteur - CNRS, France
X-Ray Structure of Bacterial Cys-Loop Receptor-Channels: Structural Basis of Allosteric Mechanism
Hassane S. Mchaourab, Vanderbilt University, USA
Functional Dynamics of Active Transporters: A Spin Labeling Perspective
Olga Boudker, Weill Cornell Medical College, USA
Transport Mechanism of Glutamate Transporters
Short Talk to be Chosen from Abstracts,
7:00 - 8:00 PM Social Hour w/ Lite Bites Chamisa Ballroom 2
8:00 - 11:00 PM Entertainment Chamisa Ballroom 2
Friday, January 28
Departure
      *=Session Chair     †=Speaker invited, not yet responded.



Keystone Symposia would like to thank the sponsor of this meeting for their generous support:

We gratefully acknowledge additional support for this conference from:

Heptares Theraputics Ltd



We gratefully acknowledge the generous grant for this conference provided by:

National Institutes of Health
National Institute of General Medical Sciences (NIGMS)

Grant No. 1R13GM094985-01


The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.


We gratefully acknowledge the organizations that provide Keystone Symposia with additional support, such as marketing and advertising...

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Cellular membranes present natural borders for signal transduction between cells and their environment. Nature developed different strategies to enable signals to cross the membrane barrier. The goal of this meeting is to discuss the molecular mechanisms of transmembrane signaling on the basis of three protein classes, i.e. G protein-coupled receptors, ion channels and transporters. Available protein structures together with biophysical and functional approaches will provide guidance to explore similarities and differences of the underlying mechanisms. Exemplified will be receptors and channels as well as proteins with dual or modified functions, such as channelrhodopsin. A comparative view is thought to bring researchers from diverse fields together and to stimulate further development of transmembrane signaling proteins in drug discovery and fighting disease.