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Chemical Senses: Receptors and Circuits (C7)

Organizer(s): Leslie B. Vosshall and Peter Mombaerts
March 15 - 19, 2009
Granlibakken Resort  ·  Tahoe City, California
Abstract Deadline: November 17, 2008
Late Abstract Deadline: December 15, 2008
Scholarship Deadline: November 17, 2008
Early Registration Deadline: January 15, 2009


Supported by the Directors' Fund



This meeting took place in the 2009 season.

For a complete list of the meetings for the upcoming/current season,
see our meeting list, or search for a meeting.
Summary of Meeting
The goal of this Keystone Symposium is to bring together both pioneers and newcomers to the neurobiology of the chemical senses to discuss the development and function of neuronal circuits that underlie the perception of odorants, tastants, and pheromones. In the decade since the identification of molecular receptors for chemosensory stimuli, the field is increasingly moving toward questions of how sensory circuits are assembled during development and how they function in mediating chemosensory perception. Researchers are elucidating the molecules and mechanisms that pattern connections from the periphery to the brain. Using electrophysiological and imaging techniques, information processing is being studied mostly at the periphery. However, there is little information about how information is propagated from lower pathways to the cortex (or equivalent) and other higher brain regions. This meeting will highlight recent results using developmental, electrophysiological, functional imaging, and behavioral approaches to elucidate how chemosensory signals are processed in invertebrate and vertebrate model systems, ranging from nematode, fruit fly, zebrafish, mouse, rat, non-human primate to human.

Sunday, March 15
3:00 - 7:30 PM Registration Pre Function
6:30 - 7:30 PM Welcome and Buffet Dinner Granhall
7:30 - 8:30 PM Opening Lecture Mountain
Peter Mombaerts, Max Planck Institute of Biophysics
The P Element
8:30 - 10:00 PM Workshop 1: Neuroethology and Behavior Mountain
Hitoshi Sakano, University of Tokyo
Molecular Basis of Odor Perception in the Mouse
Bill S. Hansson, Max Planck Institute for Chemical Ecology
Fruitfly Olfactory Neuroethology
Timothy E. Holy, Washington University in St. Louis
The Mammalian Accessory Olfactory System: Stimuli and Circuitry
Monday, March 16
7:00 - 8:00 AM Breakfast Granhall
8:00 - 11:15 AM Molecular Biology of Smell and Taste Mountain
Liqun Luo, Stanford University
Wiring Up the Fly Olfactory Circuit
Leslie B. Vosshall, Rockefeller University
DEET and Beyond: Harnessing Insect Olfaction to Develop New Repellents
Richard Benton, University of Lausanne
Short Talk: Variant Ionotropic Glutamate Receptors as Chemosensory Receptors in Drosophila
Hubert Amrein, Duke University
Short Talk: Sweet Taste Perception in Drosophila
Alain Trembleau, University Pierre & Marie Curie
Evidence for a Developmentally-Regulated Local Translation of Odorant Receptor mRNAs in Axons of Olfactory Sensory Neurons
Takeshi Imai, University of Tokyo
Short Talk: Pre-Target Axon-Axon Interactions Establish the Neural Map Topography
Xiaodong Li, Senomyx, Inc.
Short Talk: Molecular Mechanisms for Enhancement of T1R Taste Receptors
Dennis Drayna, National Institutes of Health
Short Talk: Population-Specific Genetic Variants Control Human Sweet Taste Sensitivity
9:20 - 9:40 AM Coffee Break Pre Function
11:15 AM - On Own for Lunch
11:15 AM - 1:00 PM Poster Setup Bay
1:00 - 10:00 PM Poster Viewing Bay
4:30 - 5:00 PM Coffee Available Pre Function
5:00 - 7:30 PM Pain/Olfactory Circuits I Mountain
David Julius, University of California, San Francisco
From Peppers to Peppermints: Natural Products as Probes of the Pain Pathway
Ardem Patapoutian, The Scripps Research Institute
TRP Channels and Nociception
Joel D. Mainland, Duke University
Short Talk: Cracking the Code: Translating Odorants into Olfactory Receptor Responses
Gilles J. Laurent, Max-Planck-Institute for Brain Research
Neural Coding of Olfactory Information
Rainer Friedrich, Friedrich Miescher Institute for Biomedical Research
Transformation of Odor Representations in the Olfactory Bulb and Beyond
7:30 - 8:30 PM Dinner Granhall
8:00 - 10:00 PM Poster Session 1 Bay
8:00 - 9:00 PM Social Hour Bay
Tuesday, March 17
7:00 - 8:00 AM Breakfast Granhall
8:00 - 11:15 AM Olfactory Circuits II Mountain
Rachel Wilson, Harvard Medical School
Olfactory Processing in the Drosophila Brain
Gero Miesenboeck, University of Oxford
Signals and Noise in Olfactory Circuits
Matt Wachowiak, Boston University
Low-Level Mechanisms for Processing Odor Information in the Behaving Animal
Gary L. Westbrook, Oregon Health & Science University
The Interplay between Chemical and Electrical Synapses in Olfactory Bulb Glomeruli
Haiqing Zhao, Johns Hopkins University
Short Talk: ANO2, a Calcium-Activated Chloride Channel in Vertebrate Olfactory Transduction
Hartwig Spors, Max Planck Institute of Biophysics
Short Talk: In vivo Imaging of Mice with Genetically Labeled Glomeruli
9:20 - 9:40 AM Coffee Break Pre Function
11:15 AM - On Own for Lunch
11:15 AM - 1:00 PM Poster Setup Bay
1:00 - 10:00 PM Poster Viewing Bay
1:00 - 4:30 PM Workshop 2: 50 Years of Pheromone Research Mountain
Tristram Wyatt, University of Oxford
Pheromones at 50 - From Birth to Maturity
Marie-Christine Broillet, University of Lausanne
The Mouse Grueneberg Ganglion: A Danger Detector
Joerg Fleischer, Institute of Physiology
Short Talk: Grueneberg Ganglion – a Dual Sensory Organ?
Liming Sun, National Institute of Biological Sciences, Beijing
Short Talk: Guanylyl Cyclase-D in the Olfactory CO2 Neurons is Activated by Bicarbonate
Kazushige Touhara, University of Tokyo
Chemosensory Receptor and Behavior
Darren W. Logan, The Scripps Research Institute
Short Talk: Suckling is Promoted by Innate Conditioning via Non-Specialist Olfactory Circuits
Albert Folch, University of Washington
Large-Scale Search for Pheromone-Specialist Olfactory Sensory Neurons using a Microfluidic Platform
Frank Zufall, University of Saarland
Sensory Adaptation in the Vomeronasal Organ
4:30 - 5:00 PM Coffee Available Pre Function
5:00 - 7:00 PM Pheromone Processing Mountain
Lisa T. Stowers, The Scripps Research Institute
Molecular Mechanisms of Pheromone Detection
Yoram Ben-Shaul, Harvard University
The Mouse AOB: New Insights into Vomeronasal Chemosensory Processing
Hiroaki Matsunami, Duke University Medical Center
Short Talk: Translating Odorants into Olfactory Receptor Responses
Ivanka Savic, Karolinska Institutet
Visualizing Pheromone Perception in the Human Brain
Monika C. M. Frey, Universität Würzburg
Short Talk: Don´t Run Away! – A Human Pheromone as an Unconscious Safety Signal
Ivan Rodriguez, University of Geneva
V1R Monogenic Expression: Copycat or Unique Mechanism?
7:00 - 8:00 PM Dinner Granhall
8:00 - 10:00 PM Poster Session 2 Bay
8:00 - 9:00 PM Social Hour Bay
Wednesday, March 18
7:00 - 8:00 AM Breakfast Granhall
8:00 - 11:15 AM Behavior Mountain
Mario de Bono, University of Cambridge
Evolutionary Sculpting of Foraging in C. elegans
Cornelia (Cori) Bargmann, Rockefeller University
Half a Wiring Diagram is Better than None: Generating Flexible Olfactory Behaviors from a Fixed Anatomy
David J. Anderson, California Institute of Technology
Role of Chemosensation in the Regulation of Aggression in Drosophila
Zach Mainen, Instituto Gulbenkian de Ciencia
Neural Mechanisms of Olfactory-Guided Decisions in Rodents
Julia L. Semmelhack, University of California, San Diego
Short Talk: Select Glomeruli in the Drosophila Antennal Lobe Mediate Innate Olfactory Attraction and Aversion
Ron Congrong Yu, Stowers Institute for Medical Research
Altered Odor Response and Discrimination in Mice with Multi Glomerular Maps
9:20 - 9:40 AM Coffee Break Pre Function
11:15 AM - On Own for Lunch
4:30 - 5:00 PM Coffee Available Pre Function
5:00 - 6:20 PM Cortex and Beyond Mountain
Donald A. Wilson, Nathan Kline Institute and New York University School of Medicine
Olfactory Cortical Processing
Edmund T. Rolls, Oxford Centre for Computational Neuroscience
Multimodal Sensory Integration in and beyond the Orbitofrontal Cortex
Denise Chen, Rice University
Short Talk: Encoding Human Sexual Chemosensory Cues in the Orbitofrontal and Fusiform Cortices
Markus Knaden, Max Planck Institute for Chemical Ecology
Short Talk: Smell Stereo: How Desert Ants Take Olfactory Snapshots
7:00 - 7:30 PM Closing Lecture Mountain
Linda Buck, Fred Hutchinson Cancer Research Center
Olfactory Mechanisms in Mammals
7:30 - 8:30 PM Social Hour Alumni
8:00 - 9:00 PM Dinner Granhall
8:00 - 11:00 PM Entertainment Granhall
Thursday, March 19
Departure
*Session Chair   †Speaker invited, not yet responded.



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