| Friday, October 9 |
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3:00 - 7:00 PM
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Registration
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Marquis Foyer
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| Saturday, October 10 |
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7:30 - 8:30 AM
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Breakfast
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Kalinda Restaurant
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8:30 - 9:30 AM
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Keynote Address
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Marquis Room
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*
Michael B. Kastan,
St. Jude Children's Research Hospital
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Stephen C. West,
Cancer Research UK
Defects in DNA Strand Break Repair and Links to Inheritable Disease
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9:30 AM - 12:30 PM
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DNA Damage Sensing and Signaling 1
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Marquis Room
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*
Alan D. D'Andrea,
Dana-Farber Cancer Institute
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Martin F. Lavin,
Queensland Institute for Medical Research
DNA Damage Signaling through the MRN Complex
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Roger A. Greenberg,
University of Pennsylvania School of Medicine
Ubiquitin Recognition and Remodeling at DNA Double Strand Breaks
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David Faucher,
Universite de Sherbrooke
Short Talk: Methylated H3K4, a Transcription Associated Histone Modification, is Involved in the DNA Damage Response Pathway
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Jiri Lukas,
Danish Cancer Society
Dynamic Organization of the DNA Damage Response in Space and Time
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9:50 - 10:10 AM
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Coffee Break
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Marquis Foyer
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12:30 - 1:30 PM
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Poster Setup
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Monarch Room
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1:30 - 10:00 PM
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Poster Viewing
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Monarch Room
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4:30 - 5:00 PM
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Coffee Available
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Marquis Foyer
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5:00 - 7:00 PM
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Telomeres and DNA Damage Response
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Marquis Room
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*
Roger R. Reddel,
Children’s Medical Research Institute, Sydney
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Titia de Lange,
Rockefeller University
Persistent Telomere Damage Induces By-Pass of Mitosis and Tetraploidy
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Michael B. Kastan,
St. Jude Children's Research Hospital
ATM-Dependent DNA Damage Signaling
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Fuyuki Ishikawa,
Kyoto University
RPA-like Mammalian Ctc1-Stn1-Ten1 Complex Binds to Single-Stranded DNA and Protects Telomeres Independently of the Pot1 Pathway
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Eric Gilson,
Université de Lyon
TRF2 and Apollo Protect the Inner Part of Human Telomeres
from Replicative Damages
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Amy D. Gelinas,
University of Colorado at Boulder
Short Talk: Telomere Capping Proteins are Structurally Related to RPA
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Monarch Room
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7:30 - 10:00 PM
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Poster Session 1
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Monarch Room
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| Sunday, October 11 |
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7:30 - 8:30 AM
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Breakfast
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Kalinda Restaurant
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7:30 - 8:30 AM
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Poster Setup
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Monarch Room
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8:00 AM - 5:30 PM
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Poster Viewing
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Monarch Room
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8:30 - 11:30 AM
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DNA Repair 1
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Marquis Room
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*
Jan Karlseder,
The Salk Institute
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Alan D. D'Andrea,
Dana-Farber Cancer Institute
The Fanconi Anemia Pathway and the DNA Damage Response
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Camilla Sjögren,
Karolinska Institute
The SMC5/6 Complex – More than Repair?
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Judith L. Campbell,
California Institute of Technology
Short Talk: The Roles of Yeast and Human Dna2 in Nuclear DNA DSB Repair and Telomere
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Maria Jasin,
Memorial Sloan-Kettering Cancer Center
Double Strand Break Repair Pathways
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Jörg Heierhorst,
St. Vincent's Institute of Medical Research
Short Talk: Role of the Rad53 SQ/TQ Cluster Domain as a Phospho-Counting Switch in the DNA Damage Response
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9:50 - 10:10 AM
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Coffee Break
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Marquis Foyer
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11:30 AM - 12:30 PM
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Lunch
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Monarch Room
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12:30 - 3:00 PM
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Poster Session 2
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Monarch Room
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3:00 - 3:30 PM
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Coffee Available
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Marquis Foyer
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3:30 - 5:30 PM
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BIR and ALT
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Marquis Room
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*
Maria Jasin,
Memorial Sloan-Kettering Cancer Center
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Peter M. Burgers,
Washington University School of Medicine
A Tale of Two Tails: Activation of the Mec1/ATR Checkpoint Kinase by 9-1-1 and by Dpb11/TopBp1
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Michael J. McEachern,
University of Georgia
Studies of Telomere Maintenance in the ALT-like stn1-M1 Mutant of Kluyveromyces lactis
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Roger R. Reddel,
Children’s Medical Research Institute, Sydney
ALT-like Activity in Normal Mammalian Somatic Cells In Vivo
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Hyunsook Lee,
Seoul National University
Short Talk: BRCA2 is Involved in Telomere End Protection through Suppression of ALT-like Telomeric Recombination
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5:30 PM -
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On Own for Dinner
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| Monday, October 12 |
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7:30 - 8:30 AM
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Breakfast
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Kalinda Restaurant
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8:30 - 11:30 AM
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Telomerase/Control of Telomerase
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Marquis Room
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*
Titia de Lange,
Rockefeller University
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Steven Artandi,
Stanford University
Telomerase Assembly, Telomere Synthesis and Wnt Signaling
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Raymund J. Wellinger,
University of Sherbrooke
Adaptation to Telomere Uncapping in Yeast
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Prabhat Khadka,
Yonsei University
Short Talk: KIP Modulates Telomerase Activity through Interaction with TRF2
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Virginia A. Zakian,
Princeton University
The Role of the Pif1 DNA Helicase in Maintaining Telomere Length
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Martina M. Stagno d'Alcontres,
Centro Nacional de Investigaciones Oncologicas
Short Talk: TPP1 Recruits TERT to Chromatin and Positively Regulates Telomere Length, Maintains Telomere Integrity and Prevents Premature Development of Degenerative Pathologies in Mice
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Ken Masutomi,
National Cancer Center
Short Talk: A Mammalian RNA Dependent RNA Polymerase Formed by hTERT and the RNA Component of RNase MRP
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9:50 - 10:10 AM
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Coffee Break
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Marquis Foyer
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11:30 AM - 1:00 PM
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Poster Setup
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Monarch Room
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1:00 - 10:00 PM
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Poster Viewing
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Monarch Room
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4:30 - 5:00 PM
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Coffee Available
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Marquis Foyer
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5:00 - 7:15 PM
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DNA Damage Sensing and Signaling 2
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Marquis Room
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*
Virginia A. Zakian,
Princeton University
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Junjie Chen,
University of Texas M. D. Anderson Cancer Center
DNA Damage Signaling and DNA Repair
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Amanda Wraith Kijas,
Queensland Institute of Medical Research
Short Talk: Autophosphorylation and ATM Activation: Additional Sites Add to the Complexity
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Jan Karlseder,
The Salk Institute
Telomere Driven Epigenetic Reprogramming during Cellular Aging
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Zeenia Kaul,
Children's Medical Research Institute
Short Talk: Five Dysfunctional Telomeres Precede Cellular Senescence in Normal Human Diploid Fibroblasts
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Woodring E. Wright,
University of Texas Southwestern Medical Center
The Comparative Biology Of Replicative Senescence
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7:15 - 8:15 PM
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Social Hour w/ Lite Bites
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Monarch Room
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7:30 - 10:00 PM
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Poster Session 3
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Monarch Room
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| Tuesday, October 13 |
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7:30 - 8:30 AM
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Breakfast
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Kalinda Restaurant
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8:30 - 11:30 AM
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DNA Repair 2
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Marquis Room
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*
Camilla Sjögren,
Karolinska Institute
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Frederick W. Alt,
HHMI, Children's Hospital and Immune Disease Institute, Boston
DNA Double Strand Breaks, Translocations and B Cell Lymphoma
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David O. Ferguson,
University of Michigan
Multiple Roles of MRN in Double Strand Break Repair Pathways
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Marco F. Foiani,
Instituto FIRC di Oncologia Molecolare
The DNA Damage Response during DNA Replication
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Huiling Xu,
Peter MacCallum Cancer Centre
Short Talk: Cohesin-Mediated Modulation of Radiation-Induced DNA Damage Response
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Claudia Lukas,
Danish Cancer Society
Short Talk: 53BP1 Nuclear Bodies: A Dynamic, Cell-Cycle-Regulated Surrogate of Replication, Proteotoxic, and Transcription-Coupled Genomic Stress
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9:50 - 10:10 AM
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Coffee Break
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Marquis Foyer
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4:30 - 5:00 PM
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Coffee Available
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Marquis Foyer
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5:00 - 7:00 PM
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Telomeres, DNA Repair and Human Disease
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Marquis Room
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*
Steven Artandi,
Stanford University
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Monica Bessler,
Washington University School of Medicine
Dyskeratosis Congenita
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Katharina Schlacher,
Sloan-Kettering Institute
Short Talk: BRCA2 (FANCD1) Protects Stalled Replication Forks from Degradation, a Novel Pathway Shared with BRCA1 and Fanconi Anemia
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Peter J. McKinnon,
St. Jude Children's Research Hospital
Differential ATM Signaling from DNA Strand Breaks and Dysfunctional Telomeres
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Jerry W. Shay,
University of Texas Southwestern Medical Center
Will Telomerase Inhibitors Target Cancer Stem Cells?
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Monarch Room
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8:00 - 11:00 PM
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Entertainment
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Monarch Room
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| Wednesday, October 14 |
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Departure
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