| Wednesday, June 10 |
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3:00 - 7:30 PM
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Registration
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Shavano Peak Foyer
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6:30 - 7:30 PM
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Refreshments
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Shavano Peak Foyer
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7:30 - 7:45 PM
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Welcome Remarks
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Red Cloud/Crestone
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Frank J. Slack,
Yale University
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7:45 - 8:45 PM
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Keynote Address
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Red Cloud/Crestone
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Joan Massagué,
Memorial Sloan-Kettering Cancer Center
Deconstructing Metastasis
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| Thursday, June 11 |
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7:30 - 8:30 AM
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Breakfast
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Shavano/Torreys
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8:30 - 11:00 AM
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Regulation of Development by miRNAs
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Red Cloud/Crestone
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Helge Großhans,
Friedrich Miescher Institute (FMI)
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Alexander F. Schier,
Harvard University
MicroRNAs in Embryogenesis
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Amy E. Pasquinelli,
University of California, San Diego
Regulation of Gene Expression by MicroRNAs in C. elegans
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Eric C. Lai,
Sloan-Kettering Institute
Biogenesis and Function of Short Regulatory RNAs in Drosophila
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Seogang Hyun,
Seoul National University
Short Talk: Conserved microRNA miR-8 and its Target USH Control Body Size by Regulating Insulin Signaling in Fat Calls
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Silvia Monticelli,
Institute for Research in Biomedicine
Short Talk: MicroRNAs in Mast Cells
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Debora Marks,
Harvard Medical School
Short Talk: Transfection of Small RNAs Globally Perturbs Gene Regulation by Endogeneous microRNAs
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9:50 - 10:10 AM
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Coffee Break
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Shavano Peak Foyer
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11:45 AM -
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On Own for Lunch
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11:45 AM - 1:00 PM
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Poster Setup
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Shavano/Torreys
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1:00 - 10:00 PM
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Poster Viewing
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Shavano/Torreys
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2:30 - 4:30 PM
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Workshop 1: Bench to Bedside: Translating miRNA Discoveries into Clinical Applications
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Red Cloud/Crestone
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Joanne B. Weidhaas,
Yale University School of Medicine
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Doyel Mitra,
University of Colorado Denver
The Role of the Histone Demethylase JARID1b in the Regulation of miRNA Expression in Breast Cancer Cells
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Helen M. Heneghan,
National University of Ireland, Galway
Circulating miRNAs as Novel Minimally Invasive Biomarkers for Breast Cancer
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Galina Gabriely,
Brigham and Women's Hospital
The Role of Onco-MicroRNA miR-21 in Gliomagenesis
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Stoil D. Dimitrov,
Dana-Farber Cancer Institute
Regulation of BRCA1 Expression by MicroRNA-545
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Dalia Cohen,
Rosetta Genomics
Identification of Tumor Tissue Origin by a MicroRNA-based Molecular Assay
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Kim A. Lennox,
Integrated DNA Technologies
A Direct Comparison of miRNA Antagonist Potency
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Yan Li,
National Eye Institute
Characterization of a Corneal/Lens-Specific miRNA Gene, miR-184
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Karen Angelica Cavassani,
University of Michigan Medical School
microRNA as Regulators of Tumor Growth in Post-Septic Hosts
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4:30 - 5:00 PM
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Coffee Available
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Shavano Peak Foyer
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5:00 - 7:00 PM
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Gene Regulation by Non-Coding RNAs
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Red Cloud/Crestone
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Alla Grishok,
Columbia University Medical Center
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John S. Mattick,
University of Queensland
The Hidden Layer of Regulatory RNA in Evolution, Development and Cognition
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George A. Calin,
University of Texas - M.D. Anderson Cancer Center
A Noncoding RNA Revolution in the Cancer Society
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Mark A. Kay,
Stanford University
The Role of Small RNAs in Gene Regulation
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Yong Sun Lee,
University of Texas Medical Branch
Short Talk: A Novel Class of Small RNAs, tRNA-Derived RNA Fragments (tRFs), is Highly Expressed in Proliferating Cells and Required for Cell Proliferation
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Shavano/Torreys
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7:30 - 10:00 PM
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Poster Session 1
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Shavano/Torreys
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| Friday, June 12 |
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7:30 - 8:30 AM
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Breakfast
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Shavano/Torreys
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8:30 - 11:45 AM
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MicroRNAs in Cancer
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Red Cloud/Crestone
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Scott M. Hammond,
University of North Carolina at Chapel Hill
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Curtis C. Harris,
NCI, National Institutes of Health
Inflamation and Cancer: Microenvironment, Inflamatory Cytokines microRNA and p53
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Frank J. Slack,
Yale University
In vivo Role for miR-34 in Radiation Response
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Joshua Mendell,
Johns Hopkins University
MicroRNA Reprogramming in Cancer: Mechanisms and Therapeutic Opportunities
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Carlo M. Croce,
Ohio State University
Role of microRNAs in Human Cancer
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Mathijs Voorhoeve,
Duke-NUS Graduate Medical School
Short Talk: Genetic Dissection of the Role of microRNAs and Other ncRNAs in Cancer
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Florian Kuchenbauer,
Terry Fox Laboratory
Short Talk: Emerging Evidence of Differential Expression of miRNA*s and its Contribution to the Development of Acute Myeloid Leukemia
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9:50 - 10:10 AM
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Coffee Break
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Shavano Peak Foyer
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11:45 AM -
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On Own for Lunch
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11:45 AM - 1:00 PM
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Poster Setup
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Shavano/Torreys
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1:00 - 10:00 PM
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Poster Viewing
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Shavano/Torreys
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4:30 - 5:00 PM
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Coffee Available
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Shavano Peak Foyer
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5:00 - 7:00 PM
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Hot Topics in miRNA Research
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Red Cloud/Crestone
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Lin He,
University of California, Berkeley
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Hannele Ruohola-Baker,
University of Washington
microRNAs Function in Stem Cells
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Eric G. Marcusson,
Regulus Therapeutics
Therapeutic Targeting of miRNA
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Isidore Rigoutsos,
International Business Machines Corporation
Evidence of an Expanded Role of microRNAs Going Beyond the 3'UTR
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Zain Paroo,
University of Texas Southwestern Medical Center
Short Talk: Phosphorylation of the Human Micro-RNA Generating Complex Mediates MAPK/Erk Signaling
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Shavano/Torreys
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7:30 - 10:00 PM
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Poster Session 2
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Shavano/Torreys
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| Saturday, June 13 |
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7:30 - 8:30 AM
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Breakfast
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Shavano/Torreys
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8:30 - 11:45 AM
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Mechanisms of miRNA Form and Function
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Red Cloud/Crestone
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George A. Calin,
University of Texas - M.D. Anderson Cancer Center
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Jennifer A. Doudna,
University of California, Berkeley
Biogenesis of small regulatory RNAs
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Marianthi Kiriakidou,
University of Pennsylvania School of Medicine
Mamalian Ago2 in vitro and in vivo in Cancer
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Alla Grishok,
Columbia University Medical Center
Gene Expression Regulation by Endogenous RNAi and Rb in C. elegans
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Elaine Fuchs,
HHMI/Rockefeller University
MicroRNA Regulation in Skin Stem Cells: Fine Tuning the Balance between Growth and Differentiation
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Liang Zhang,
Rockefeller University
Short Talk: Systematic Analysis of Dynamic miRNA-Target Interactions during C. elegans Development
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Ulrich Tschulena,
DKFZ
Short Talk: A Novel Large-Scale Screen to Identify Modulators of miR-21
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9:50 - 10:10 AM
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Coffee Break
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Shavano Peak Foyer
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11:45 AM -
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On Own for Lunch
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11:45 AM - 1:00 PM
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Poster Setup
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Shavano/Torreys
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1:00 - 10:00 PM
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Poster Viewing
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Shavano/Torreys
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2:30 - 4:30 PM
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Workshop 2: Emerging Ideas and Technologies in Small RNAs
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Red Cloud/Crestone
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Allison L. Abbott,
Marquette University
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Carl D. Novina,
Dana Farber Cancer Institute
Identification of microRNA-Mediated Tumor Suppressive Activity in Melanoma
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Angela Anderegg,
Northwestern University
The Role of MicroRNAs in Midbrain Dopaminergic Neurogenesis
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Jennifer Young,
Centenary Institute
Regulation of Angiogenesis by MicroRNAs
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Lu Ping Tan,
University Medical Center Groningen
A High Throughput Experimental Approach to Identify miRNA Target , in Human Cells
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Ivan Martinez,
Yale University
Rb-Dependent Cellular Senescence Induce the Expression of
miR-29 and miR-30 that Target the Cell Cycle Regulatory Gene MYBL2
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Aleishia Geraldine Harris,
Stanford School of Medicine
Epstein-Barr Virus Latent Membrane Protein 1 Modulates Host MicroRNAs in B Cell Lymphomas
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Andrei Thomas-Tikhonenko,
Children's Hospital of Philadelphia & Univ of Pennsylvania
Clusterin, an Inhibitor of Tumor Growth and Angiogenesis, is Negatively Regulated by c-Myc though miR-17-92 and the type II TGFbeta Receptor
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4:30 - 5:00 PM
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Coffee Available
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Shavano Peak Foyer
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5:00 - 7:00 PM
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Roles of Small RNAs in Cancer
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Red Cloud/Crestone
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Joshua Mendell,
Johns Hopkins University
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Aurora Esquela-Kerscher,
Eastern Virginia Medical School
The Role of miRNAs during Development and Cancer Progression
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Bryan R. Cullen,
Duke University Medical Center
Herpesvirus microRNAs and Cancer
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Judy Lieberman,
Harvard Medical School
miRNAs and Breast Cancer also Small RNAs as Therapeutics
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Joel Neilson,
Baylor College of Medicine
Short Talk: 3' UTR Dynamics in Cellular Activation and Transformation
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Shavano/Torreys
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7:30 - 10:00 PM
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Poster Session 3
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Shavano/Torreys
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| Sunday, June 14 |
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7:30 - 8:30 AM
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Breakfast
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Shavano Peak
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8:30 - 11:45 AM
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MiRNAs as Diagnostics and Therapeutics
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Red Cloud/Crestone
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Aurora Esquela-Kerscher,
Eastern Virginia Medical School
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Michele A. Cleary,
Merck & Co., Inc
miRNAs as Diagnostics and Therapeutics
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Lin He,
University of California, Berkeley
Functional Dissection of miR-17-92 Oncogene
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Joanne B. Weidhaas,
Yale University School of Medicine
A MicroRNA Binding Site Polymorphism as a Biomarker of Cancer Risk
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Scott M. Hammond,
University of North Carolina at Chapel Hill
MicroRNAs in Development and Disease
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Sónia A. Melo,
IDIBELL - PEBC Program Barcelona/GABBA Program Portugal
Short Talk: microRNA Machinery in Human Cancer
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Alexander Pertsemlidis,
University of Texas Southwestern Medical Center
Short Talk: miR-337 Modulates Sensitivity to Paclitaxel in Non-Small Cell Lung Cancer
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9:50 - 10:10 AM
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Coffee Break
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Shavano Peak Foyer
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11:45 AM -
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On Own for Lunch
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4:30 - 5:00 PM
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Coffee Available
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Shavano Peak Foyer
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5:00 - 7:00 PM
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Lessons from Developmental Biology
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Red Cloud/Crestone
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Eric C. Lai,
Sloan-Kettering Institute
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Allison L. Abbott,
Marquette University
Genetic Analysis of microRNA Functions in C. elegans Development
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Helge Großhans,
Friedrich Miescher Institute (FMI)
Life and Death of MicroRNAs
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David Brown,
Asuragen Inc.
Therapeutic Applications of a miR-34 Mimic
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Eric Alexander Miska,
University of Cambridge
Short Talk: Genetic Analysis in C. elegans Reveals New Insights into miRNA Mechanism
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7:00 - 7:15 PM
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Closing Remarks
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Red Cloud/Crestone
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Amy E. Pasquinelli,
University of California, San Diego
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7:15 - 8:15 PM
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Social Hour w/ Lite Bites
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Shavano Peak
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8:00 - 11:00 PM
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Entertainment
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Shavano Peak
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| Monday, June 15 |
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Departure
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