| Tuesday, May 12 |
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3:00 - 7:30 PM
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Registration
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Jinyun Foyer
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6:30 - 7:30 PM
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Refreshments
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Jinyun Foyer
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7:30 - 8:30 PM
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Keynote Address
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Jinyun Ballroom
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Lennart Hammarström,
Karolinska Institute
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Xiao-Jun Xu,
Peking University Health Science Center
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Jean-Laurent Casanova,
Rockefeller University
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Xiao-Ming Gao,
Peking University Health Science Center
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Xuetao Cao,
Second Military Medical University
Immune Regulation by Antigen-Presenting Cells: From Basic to Clinic
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8:30 - 9:30 PM
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Orientation for New Attendees and New Investigators
Keystone Symposia's Chief Scientific Officer, Dr. Andy Robertson, to lead discussion in a "What to Expect during your Attendance" for interested delegates.
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Jinyun Ballroom
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| Wednesday, May 13 |
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7:30 - 8:30 AM
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Breakfast
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Four Seasons Restaurant
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7:30 - 8:30 AM
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Poster Setup
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Jinyun Ballroom
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8:30 - 11:30 AM
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Development of Immunity
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Jinyun Ballroom
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Lennart Hammarström,
Karolinska Institute
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Jean-Laurent Casanova,
Rockefeller University
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Tasuku Honjo,
Kyoto University Graduate School of Medicine
The Molecular Mechanism for Generation of Antibody Memory
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Michael S. Neuberger,
Medical Research Council
The Functions of AID and other DNA Deaminases in Immunity
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Max D. Cooper,
Emory University
Convergent Evolution of Adaptive Immunity
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Yaofeng Zhao,
China Agricultural University
Short Talk: Ornithorhynchus anatinus (platypus) Links the Evolution of Immunoglobulin Genes in Eutherian Mammals and Lower Tetrapods
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10:10 - 10:30 AM
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Coffee Break
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Jinyun Foyer
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11:30 AM - 12:30 PM
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Lunch
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Four Seasons Restaurant
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12:15 - 3:00 PM
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Poster Session 1
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Jinyun Ballroom
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2:30 - 3:00 PM
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Coffee Available
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Jinyun Foyer
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3:00 - 5:00 PM
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Antibody Deficiencies
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Jinyun Ballroom
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Qiang Pan-Hammarström,
Karolinska Institute
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Xi-Qiang Yang,
Chongqing University of Medical Sciences
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Mary Ellen Conley,
St. Jude Children's Research Hospital
Defects in Early B Cell Development
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Lennart Hammarström,
Karolinska Institute
Genetics of IgAD and CVID
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Yu Lung Lau,
University of Hong Kong
Primary Immunodeficiencies in Hong Kong
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Stuart G. Tangye,
Garvan Institute of Medical Research
Short Talk: B Cell Differentiation and Function in Patients with Defects in STAT3 Signaling
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5:00 PM -
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On Own for Dinner
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| Thursday, May 14 |
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7:30 - 8:30 AM
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Breakfast
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Four Seasons Restaurant
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8:30 - 11:45 AM
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Non-B Cell PIDs
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Jinyun Ballroom
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Alain Fischer,
CHU Necker
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Xiao-Jun Xu,
Peking University Health Science Center
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Luigi D. Notarangelo,
Children's Hospital, Boston
Human and Mice Models of Omenn Syndrome and Leaky SCID: Unraveling the Paradox of Autoreactivity, Immunopathology and Immune Deficiency
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Yoshiyuki Minegishi,
Tokyo Medical and Dental University
Molecular Basis of Hyper IgE Syndrome (HIES)
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Jean Pierre de Villartay,
INSERM U768
DNA Repair in the Immune System: From V(D)J to IG Class Switch Recombination
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Amos Etzioni,
Rambam Medical Center
Leukocyte Adhesion Defects
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Bodo Grimbacher,
Royal Free Hospital & University College Medical School
The Involvement of Th17 Cells in Primary Immunodeficiencies
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10:10 - 10:30 AM
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Coffee Break
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Jinyun Foyer
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11:45 AM - 1:00 PM
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Lunch
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Four Seasons Restaurant
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1:00 - 2:30 PM
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Workshop 1
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Jinyun Ballroom
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Amos Etzioni,
Rambam Medical Center
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Xiao-Dong Zhao,
Chongqing Medical University
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Saleh Zaid Al-Muhsen,
King Saud University, and King Faisal Specialist Hospital
Molecular and Clinical Profile of a Large Cohort with Chronic Granulomatous Disease from Saudi Arabia
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Raffaele Badolato,
Universita di Brescia
Abnormal Generation of NK-T Cell Subset in Hermansky-Pudlak Type 2 Syndrome Patients
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Elissa Deenick,
Garvan Institute of Medical Research
SAP Deficient Mice Reveal New Insights into the Mechanisms of T-B Collaboration
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Liping Jiang,
Children's Hospital of Chongqing Medical University
Deficiency of TH17 Cell Numbers in Two Hyper-IgE Syndrome Patients with STAT3 Gene Mutation
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Pamela P.W. Lee,
LKS Faculty of Medicine, University of Hong Kong
Genotype-Phenotype Correlation Study in 62 Patients with X-Linked Agammaglobulinemia
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2:30 - 3:00 PM
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Coffee Available
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Jinyun Foyer
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3:00 - 4:30 PM
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Therapy for Primary Immunodeficiency Diseases
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Jinyun Ballroom
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Luigi D. Notarangelo,
Children's Hospital, Boston
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Xiao-Ming Gao,
Peking University Health Science Center
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Alain Fischer,
CHU Necker
Severe Combined Immunodeficiences (SCID): Diversity, Pathophysiology and Gene Therapy
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Matthew Porteus,
University of Texas Southwestern Medical Center
New Directions in Gene Therapy: Zinc Finger Nuclease Stimulated Homologous Recombination for the Treatement of Primary Immunodeficiencies
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4:30 PM -
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On Own for Dinner
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| Friday, May 15 |
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7:30 - 8:30 AM
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Breakfast
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Four Seasons Restaurant
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7:30 - 8:30 AM
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Poster Setup
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Jinyun Ballroom
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8:30 - 11:45 AM
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Genetics of Common Infectious Diseases
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Jinyun Ballroom
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Erwin Schurr,
Montreal General Hospital, McGill University
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Alexandre Alcaïs,
University of Paris René Descartes-INSERM U550
Human Genetics of Mycobacterial Infections
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Etienne Pays,
Universite Libre de Bruxelles
Genetics of Trypanosome Infection
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Philip M. Murphy,
National Institutes of Health
Complex Genetics of West Nile Virus Infection
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Luis Quintana-Murci,
Institut Pasteur, CNRS URA3012
Evolutionary Genetics as a Tool for Exploring New Frontiers of Host Defence
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Jean-Laurent Casanova,
Rockefeller University
A Genetic Dissection of Immunity to Infection in Natura
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10:10 - 10:30 AM
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Coffee Break
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Jinyun Foyer
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11:45 AM - 12:45 PM
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Lunch
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Four Seasons Restaurant
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12:15 - 3:00 PM
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Poster Session 2
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Jinyun Ballroom
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2:30 - 3:00 PM
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Coffee Available
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Jinyun Foyer
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3:00 - 5:00 PM
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Genetics of Common Infectious Diseases (continued)
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Jinyun Ballroom
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Philip M. Murphy,
National Institutes of Health
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Etienne Pays,
Universite Libre de Bruxelles
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Erwin Schurr,
Montreal General Hospital, McGill University
Complex Genetics of Leprosy
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Thomas B. Boren,
Umea University
Dynamics of Adhesin-Receptor interactions: Lessons from H. pylori
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Shen-Ying Zhang,
Rockefeller University
Mendelian Genetic Predisposition to Herpes Simplex Encephalitis in Childhood
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5:00 - 6:00 PM
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High Tea
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Jinyun Foyer
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6:00 - 7:30 PM
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Workshop 2
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Jinyun Ballroom
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*
Yoshiyuki Minegishi,
Tokyo Medical and Dental University
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Yu Lung Lau,
University of Hong Kong
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Kohsuke Imai,
Tokyo Medical and Dental University
Primary Immunodeficiency Database Network in Japan
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Xiao-Fei Kong,
Rockefeller University, Casanova Laboratory
A Novel form of Recessive STAT1 Deficiency Associated with
Impaired but not Abolished Responses to IFN-alpha/beta, IFN-gamma, IFN-lambda1 and IL-27
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Elin Alexandra Kindberg,
University of Linköping
A Deletion in the Chemokine Receptor 5 (CCR5) Gene is Associated with Tick-Borne Encephalitis
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Marie Meeths,
Karolinska Institutet
Spectrum and Clinical Presentation of RAB27A Mutations
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Vanessa Sancho Shimizu,
University Paris Descartes Faculty of Medicine Necker
Novel Genes Controlling Susceptibility to Herpes Simplex Encephalitis
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| Saturday, May 16 |
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7:30 - 8:30 AM
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Breakfast
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Four Seasons Restaurant
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8:30 - 11:30 AM
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Mechanism of Immunodeficiency in HIV
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Jinyun Ballroom
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Daniel E. Kaufmann,
Massachusetts General Hospital
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Margaret A. Liu,
ProTherImmune and Karolinska Institutet
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Adriano Boasso,
Imperial College London
Type I IFN and IDO-Mediated Immune Dysregulation in HIV Infection
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Frank Kirchhoff,
University of Ulm
Downregulation of Expression of MHC Class I Molecules by HIV
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Guido Silvestri,
University of Pennsylvania School of Medicine
HIV-Associated Chronic Immune Activation
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Mary Carrington,
NCI, National Institutes of Health
Immunogenetic Effects on HIV-1 Infection
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10:10 - 10:30 AM
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Coffee Break
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Jinyun Foyer
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11:30 AM -
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On Own for Lunch
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4:30 - 5:00 PM
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Coffee Available
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Jinyun Foyer
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5:00 - 6:45 PM
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Mechanism of Immunodeficiency in HIV (continued)
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Jinyun Ballroom
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Frank Kirchhoff,
University of Ulm
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Michael S. Neuberger,
Medical Research Council
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Mary Carrington,
NCI, National Institutes of Health
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Daniel E. Kaufmann,
Massachusetts General Hospital
Immunoregulatory Pathways and HIV-Specific T Cell Dysfunction
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Brent E. Palmer,
University of Colorado Health Sciences Center
Dysregulation of CD4+ T Cell Coregulatory Receptor Expression during Chronic HIV Infection
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Zuopeng Wu,
John Curtin School of Medical Research
Short Talk: Pre-mRNA Alternative Splicing is Essential in Regulating T Cell Immunity and Homeostasis
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6:45 - 7:30 PM
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Concluding Remarks
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Jinyun Ballroom
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Margaret A. Liu,
ProTherImmune and Karolinska Institutet
Common and Contrasting Mechanisms of Acquired and Inherited Immunodeficiencies
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7:30 - 8:30 PM
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Social Hour
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Jinyun Foyer
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8:30 - 9:30 PM
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Entertainment
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Jinyun Ballroom
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| Sunday, May 17 |
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Departure
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