| Friday, January 8 |
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3:00 - 7:30 PM
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Registration
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Foyer
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6:15 - 7:15 PM
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Refreshments
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Foyer
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7:15 - 7:30 PM
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Orientation for New Attendees and New Investigators
Keystone Symposia's Chief Scientific Officer, Dr. Andy Robertson, to lead discussion in a "What to Expect during your Attendance" for interested delegates.
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Peaks 1-5
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7:30 - 8:30 PM
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Keynote Session (Joint)
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Peaks 1-5
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Alasdair C. Steven,
National Institute of Arthritis, Musculoskeletal and Skin Diseases, NIH
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Ian A. Wilson,
The Scripps Research Institute
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William E. Moerner,
Stanford University
Single-Molecule Approaches to Biomolecular Dynamics and Imaging of Cellular Superstructures
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| Saturday, January 9 |
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7:00 - 8:00 AM
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Breakfast
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Summit Gallery
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8:00 - 11:15 AM
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Pushing the Limits of Structural Biology I: New and Innovative Methods (Joint)
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Peaks 1-5
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*
Kurt Wüthrich,
ETH Zurich/The Scripps Research Institute
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Andrej Sali,
University of California, San Francisco
Integrative Determination of Macromolecular Structures
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John A. Tainer,
The Scripps Research Institute
Short Talk: Proteomics Scale X-ray Solution Scattering (SAXS) to Shape Interactomes
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Ad Bax,
NIDDK, National Institutes of Health
Combining Novel Solution NMR Approaches with SAXS
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Wah Chiu,
Baylor College of Medicine
Seeing Protein Backbone and Side-Chains in Molecular Machines by Cryo-EM
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Daniel J. Müller,
University of Technology Dresden
Force Probing How Membrane Proteins
Regulate Molecular Mechanics of Cell Rounding
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Graham Johnson,
The Scripps Research Institute
Short Talk: Automated Visualization of Subcellular Environments
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9:20 - 9:40 AM
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Coffee Break
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Foyer
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11:15 AM - 1:00 PM
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Poster Setup
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Breckenridge Ballroom
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11:15 AM -
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On Own for Lunch and Recreation
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1:00 - 10:00 PM
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Poster Viewing
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Breckenridge Ballroom
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4:30 - 5:00 PM
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Coffee Available
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Foyer
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5:00 - 7:00 PM
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Macromolecular Complexes I
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Peaks 1-4
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*
Christopher P. Hill,
University of Utah
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Eva Nogales,
HHMI/University of California, Berkeley
Microtubule-Kinetochore Interactions
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Cynthia Wolberger,
Johns Hopkins School of Medicine
Insights into the Unusual Chemistry of Sir2 Enzymes
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Justin L. P. Benesch,
University of Cambridge
Short Talk: A Hybrid Approach for Determining the Structures of Protein Oligomers Comprising Heterogeneous Ensembles
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Angela M. Gronenborn,
University of Pittsburgh
Synergy between cryo-EM and NMR - Novel Findings for HIV capsid Function
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Breckenridge Ballroom
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7:30 - 10:00 PM
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Poster Session 1
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Breckenridge Ballroom
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| Sunday, January 10 |
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7:00 - 8:00 AM
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Breakfast
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Summit Gallery
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8:00 - 11:00 AM
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Membrane-Associated Phenomena
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Peaks 1-4
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Hartmut Luecke,
University of California, Irvine
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James H. Hurley,
National Institutes of Health
The ESCRT Complexes in Membrane Scission and Budding
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Christopher P. Arthur,
The Scripps Research Institute
Short Talk: Structure of Botulinum Neurotoxin Serotype B in a Lipid Bilayer at Multiple pH Levels
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Gabriel Waksman,
Birkbeck College and University College London
Structural Biology of Type IV Secretion Systems
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Mark S.P. Sansom,
University of Oxford
Multiscale Simulations of Membrane Proteins
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Jay T. Groves,
University of California, Berkeley
Spatial and Mechanical Regulation of Signal Transduction in Cell Membranes
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9:20 - 9:40 AM
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Coffee Break
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Foyer
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11:00 AM - 1:00 PM
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Poster Setup
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Breckenridge Ballroom
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11:00 AM -
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On Own for Lunch and Recreation
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1:00 - 10:00 PM
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Poster Viewing
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Breckenridge Ballroom
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2:30 - 4:30 PM
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Special Session
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Peaks 1-4
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Alasdair C. Steven,
National Institute of Arthritis, Musculoskeletal and Skin Diseases, NIH
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Vitold E. Galkin,
University of Virginia
Short Talk: High Resolution Structures of F-actin Yield New Insights into the Dynamics of Actin Filament
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Christian Biertümpfel,
NIDDK, National Institutes of Health
Short Talk: Crystal Structure of T4 Endonuclease VII Resolving a Holliday Junction
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Pingwei Li,
Texas A&M University
Short Talk: The Structural Basis of Viral RNA Recognition by RIG-I
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Mei-ting Wu,
University of Washington
Short Talk: Nanobodies were Crucial for Solving Crystal Structures from a Key Protein of an RNA-Editing Complex from the Sleeping Sickness Parasite Trypanosoma brucei
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Donald L.D. Caspar,
Florida State University
Special Lecture: Origins of Structural Biology and Trials and Errors in its History
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4:30 - 5:00 PM
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Coffee Available
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Foyer
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5:00 - 7:10 PM
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Unfolded, Alternatively Folded, and Deliberately Folded Proteins
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Peaks 1-4
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*
Mark R. Walter,
University of Alabama, Birmingham
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Joel L. Sussman,
Weizmann Institute of Science
Intrinsically Disordered Proteins (IDPs): A Role in Nervous System Development
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Alasdair C. Steven,
National Institute of Arthritis, Musculoskeletal and Skin Diseases, NIH
Amyloid Polymorphisms from Cryo-Electron Microscopy
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Beat H. Meier,
ETH Zurich
Amyloid and Prion Structure by Solid-State NMR: What Can We Learn?
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Dorothee Kern,
Brandeis University
Panorama of a Signaling Protein: Excursions in silico and in proteo
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Breckenridge Ballroom
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7:30 - 10:00 PM
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Poster Session 2
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Breckenridge Ballroom
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| Monday, January 11 |
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7:00 - 8:00 AM
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Breakfast
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Summit Gallery
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8:00 - 11:00 AM
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Pushing the Limits of Structural Biology II: Advances in Challenging Systems (Joint)
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Peaks 1-5
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Pamela J. Bjorkman,
California Institute of Technology
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Steven C. Almo,
Albert Einstein College of Medicine
Sequence, Structure, Function, Immunity
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Roger W. Hendrix,
University of Pittsburgh
The Virome and Evolutionary Relationships
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Andrew Ward,
The Scripps Research Institute
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Thomas Güttler,
Max Planck Institute for Biophysical Chemistry
Short Talk: Cargo Recognition by the Nuclear Export Receptor CRM1/Exportin1
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Erik W. Debler,
Rockefeller University
Short Talk: Characterization of the Nup84 Complex - Paradigm for the Nuclear Pore Complex Structure
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Jamie H.D. Cate,
University of California, Berkeley
Structures of the Bacterial Ribosome and the Mechanism of Translocation
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9:20 - 9:40 AM
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Coffee Break
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Foyer
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11:15 AM - 1:00 PM
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Poster Setup
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Breckenridge Ballroom
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11:15 AM -
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On Own for Lunch and Recreation
|
|
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1:00 - 10:00 PM
|
Poster Viewing
|
Breckenridge Ballroom
|
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4:30 - 5:00 PM
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Coffee Available
|
Foyer
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5:00 - 7:00 PM
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Structural Biology of Prokaryotic Cells
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Peaks 1-4
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*
Elizabeth J. Goldsmith,
University of Texas Southwestern Medical Center
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Natalie Strynadka,
University of British Columbia
Piecing Together the Type III Secretion System of Pathogenic Bacteria
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Grant J. Jensen,
California Institute of Technology
Bacterial Cryotomography
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Clara L. Kielkopf,
University of Rochester Center for RNA Biology
Short Talk: Structural Mechanism of Prokaryotic NADH/NAD+ Redox Sensing
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Ohad Medalia,
Ben-Gurion University
Structural Insight into the Nuclear Pore Complex by Cryo-Electron Tomography
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Breckenridge Ballroom
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7:30 - 10:00 PM
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Poster Session 3
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Breckenridge Ballroom
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| Tuesday, January 12 |
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7:00 - 8:00 AM
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Breakfast
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Summit Gallery
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8:00 - 11:15 AM
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Macromolecular Interactions
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Peaks 1-4
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*
Andrej Sali,
University of California, San Francisco
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James A. Wells,
University of California, San Francisco
Trapping Allosteric Transitions in Enzymes
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Pamela J. Bjorkman,
California Institute of Technology
Fc Receptors: From Molecules to Cells
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Tanja Kortemme,
University of California, San Francisco
Prediction, Design and Engineering of Protein Interactions and Networks
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Peter Kasson,
Stanford University
Short Talk: Simulations Yield New Insight into the Mechanism of Viral Membrane Fusion
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Gideon Schreiber,
Weizmann Institute
Building a Forcefield for Protein Interface Design
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Steffen Lindert,
Vanderbilt University
Short Talk: BCL::EM-Fold: Protein Folding Tool for Medium Resolution Density Maps
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9:20 - 9:40 AM
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Coffee Break
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Foyer
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11:15 AM -
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On Own for Lunch and Recreation
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4:30 - 5:00 PM
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Coffee Available
|
Foyer
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5:00 - 7:00 PM
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Macromolecular Complexes II
|
Peaks 1-4
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*
R. Andrew Byrd,
National Cancer Institute, National Institutes of Health
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Albert J.R. Heck,
Utrecht University
Native Mass Spectrometry Applied to Virus Structure and Assembly
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John (Jack) E. Johnson,
The Scripps Research Institute
Biophysical Studies of Virus Particles and their Maturation: Insights into Elegantly Programmed Nano-Machines
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G. Marius Clore,
National Institute of Diabetes and Digestive and Kidney Diseases
Short Talk: Detecting and Visualizing Sparsely Populated Protein States
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Richard W. Kriwacki,
St. Jude Children's Research Hospital
Short Talk: PUMA-Induced Dimerization of BCL-xL Releases Cytoplasmic p53 and Promotes p53-Dependent Apoptosis
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
|
Breckenridge Ballroom
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8:00 - 11:00 PM
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Entertainment
|
Breckenridge Ballroom
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| Wednesday, January 13 |
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Departure
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