| Friday, February 12 |
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3:00 - 7:30 PM
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Registration
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Van Horne Foyer
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6:30 - 7:30 PM
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Refreshments
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Van Horne Foyer
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7:30 - 8:30 PM
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Keynote Address (Joint)
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Van Horne Ballroom A-B
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Carl F. Nathan,
Weill Cornell Medical College
Non-Resolving Inflammation: Disease, Defense and Therapy
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| Saturday, February 13 |
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7:00 - 8:00 AM
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Breakfast
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Mezzanine 2
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8:00 - 11:00 AM
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Macrophages and Pathogens I
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Van Horne Ballroom A-B
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*
De'Broski R. Herbert,
Cincinnati Children's Research Foundation
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Lalita Ramakrishnan,
University of Washington
An Eicosanoid Pathway Rheostat Controls Susceptibility to Mycobacteria in Zebrafish and Humans
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Thirumala-Devi Kanneganti,
St. Jude Children's Research Hospital
Nod-like receptors: Role in immunity and inflammatory diseases
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Sabine Ehrt,
Weill Cornell Medical College
Mycobacterial Survival Strategies in the Macrophage Phagosome
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Alan Sher,
NIAID, National Institutes of Health
Poly-IC Treatment Exacerbates Tuberculosis by the Pulmonary Recruitment of a Pathogen-permissive Monocyte/macrophage Population
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9:20 - 9:40 AM
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Coffee Break
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Van Horne Foyer
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11:00 AM -
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On Own for Lunch and Recreation
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11:00 AM - 1:00 PM
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Poster Setup
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Mezzanine 2
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1:00 - 10:00 PM
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Poster Viewing
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Mezzanine 2
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2:30 - 4:30 PM
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Workshop 1
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Van Horne Ballroom A-B
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*
Lalita Ramakrishnan,
University of Washington
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Jennifer Philips,
NYU School of Medicine
Functional Genomics of the Host: Defining Macrophage Susceptibility to Mycobacterial Infection
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Dennis Montoya,
University of California, Los Angeles
Plasticity of Macrophage Phagocytic and Antimicrobial Programs in Leprosy
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Hanne Gunda Schoenen,
Institute for Clinical Microbiology and Hygiene
Mincle is Essential for Recognition and Adjuvanticity of the Mycobacterial Cord Factor and its Synthetic Analogue Trehalose-Dibehenate1
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Antoine Tinel,
Harvard Medical School
A Crucial Role for SIRT1 in Host-Defense Mechanisms
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Sandra E. Nicholson,
Walter and Eliza Hall Institute of Medical Research
The SPRY Domain-containing SOCS Box Protein SPSB2 Targets iNOS for Ubiquitination and Proteasomal Degradation
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4:30 - 5:00 PM
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Coffee Available
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Van Horne Foyer
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5:00 - 7:15 PM
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Signaling and Gene Expression (Joint)
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Van Horne Ballroom A-B
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Linda K. Curtiss,
The Scripps Research Institute
Atherosclerosis: An Unfortunate Mix of Lipids and Inflammation Whipped Up by Toll-Like Receptors
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Joachim Herz,
University of Texas Southwestern Medical Center
Importance of cholesterol homeostasis in vascular smooth muscle cells
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Petra Keul,
University of Duisburg-Essen
Short Talk: Deletion of the S1P Receptor S1P3 Attenuates Macrophage-Driven Inflammation in Atherosclerotic Lesions of S1P3-/-/ApoE -/- Double Knockout Mice
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Jay W. Heinecke,
University of Washington School of Medicine
Short Talk: Defining the Proteome of the Macrophage Foam Cell
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Ruslan M. Medzhitov,
Yale University School of Medicine
Regulation of Inflammatory Gene Expression in Macrophages
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7:15 - 8:15 PM
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Social Hour w/ Lite Bites
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Mezzanine 2
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7:30 - 10:00 PM
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Poster Session 1
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Mezzanine 2
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| Sunday, February 14 |
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7:00 - 8:00 AM
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Breakfast
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Mezzanine 2
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8:00 - 11:00 AM
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Understanding Human Macrophages
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Van Horne Ballroom A-B
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*
Peter J. Murray,
St. Jude Children's Research Hospital
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Lionel Bohdan Ivashkiv,
Hospital for Special Surgery, New York
Signal Integration during Macrophage Activation and Cytokine Production
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David Hume,
University of Edinburgh
Transcriptional Networks in Macrophage Differentiation and Activation
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Menno Van Lookeren Campagne,
Genentech, Inc.
A Central Role for Complement and Liver Kupffer Cells in Host Defense
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Christopher L. Karp,
Cincinnati Children's Hospital Research Foundation
Pathogen Contact with Human Macrophages
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Molly A. Ingersoll,
Mount Sinai School of Medicine
Short Talk: Comparison of Gene Expression Profiles between Human and Mouse Monocyte Subsets
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9:20 - 9:40 AM
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Coffee Break
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Van Horne Foyer
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11:00 AM -
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On Own for Lunch and Recreation
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11:00 AM - 1:00 PM
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Poster Setup
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Mezzanine 2
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1:00 - 10:00 PM
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Poster Viewing
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Mezzanine 2
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4:30 - 5:00 PM
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Coffee Available
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Van Horne Foyer
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5:00 - 7:00 PM
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Macrophage Movement (Joint)
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Van Horne Ballroom A-B
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*
Gerald Krystal,
British Columbia Cancer Research Center
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Israel F. Charo,
Gladstone Institute of Cardiovascular Disease
CCR2 in atherosclerosis, insulin resistance, and hematopoietic stem cell trafficking
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Frederic Geissmann,
Kings College London
: Function of the mononuclear phagocyte system: in vivo in human and model organisms
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Steven L. Kunkel,
University of Michigan Medical School
Writers, Readers, and Erasers: Dynamic Epigenetic Regulation of the Macrophage Phenotype
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Andrea L. Hevener,
University of California, Los Angeles
Short Talk: Myeloid-specific Deletion of Estrogen Receptor-alpha (ERalpha) Promotes Obesity and Insulin Resistance in Mice
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Mezzanine 2
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7:30 - 10:00 PM
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Poster Session 2
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Mezzanine 2
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| Monday, February 15 |
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7:00 - 8:00 AM
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Breakfast
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Mezzanine 2
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8:00 - 11:00 AM
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Sterile Inflammation and Cancer Inflammation
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Van Horne Ballroom A-B
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*
Christopher L. Karp,
Cincinnati Children's Hospital Research Foundation
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Kenneth L. Rock,
University of Massachusetts Medical School
The Sterile Inflammatory Response
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Vincenzo Bronte,
Istituto Oncologico Veneto
Myeloid-Derived Suppressor Cells
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Thorsten Hagemann,
Bart's and the London Queen Mary's Medical School
Cancer-Related Inflammation
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Shigekazu Nagata,
Kyoto University
Engulfment and degradation of apoptotic cells
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Antonio Castrillo,
Instituto Investigaciones Biomedicas CSIC
Short Talk: LXR Nuclear Receptors Regulate Apoptotic Cell Clearance and Immune Tolerance
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9:20 - 9:40 AM
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Coffee Break
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Van Horne Foyer
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11:00 AM -
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On Own for Lunch and Recreation
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11:00 AM - 1:00 PM
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Poster Setup
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Mezzanine 2
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1:00 - 10:00 PM
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Poster Viewing
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Mezzanine 2
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2:30 - 4:30 PM
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Workshop 2
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Van Horne Ballroom A-B
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*
Steven L. Kunkel,
University of Michigan Medical School
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Jan Van den Bossche,
Vrije Universiteit Brussel - VIB
Alternatively Activated Macrophages Engage in Homotypic and Heterotypic Interactions through IL-4 and Polyamine-Induced E Cadherin/Catenin Complexes
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Mark Gilchrist,
Institute for Systems Biology
Sumo 1 Modification and Regulation of the Transcription Factor ATF3 in Macrophages
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Karin Reif,
Genentech, Inc.
A Novel Highly Specific Small Molecule Inhibitor for BTK Suppresses Fc Receptor Function in Macrophages and Prevents Inflammatory Arthritis
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Jacob Rachmilewitz,
Goldyn Savad Institute for Gene Therapy
Cells Exposed to Sub-Lethal Oxidative-Stress Attract Monocytes via a MYD88-Linked Receptor but do not Provoke the Release of Pro-Inflammatory Cytokines
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Jessica A. Hamerman,
Benaroya Research Institute
ITAM Signaling Adapters Regulate Macrophage and Dendritic Cell Function and Homeostasis
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Amrom Obstfeld,
Columbia University
Obesity Induced Hepatic Myeloid Cells Modulate Liver Steatosis
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Suneil K. Koliwad,
Gladstone Institute of Cardiovascular Disease
Macrophage Triacylglycerol Storage as a Modulator of the Inflammatory and Metabolic Response to Dietary Fats
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Pavel Kovarik,
University of Vienna
Qualitative and Temporal Control of mRNA Decay during Inflammatory Response of Macrophages
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4:30 - 5:00 PM
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Coffee Available
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Van Horne Foyer
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5:00 - 7:00 PM
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Deactivating Macrophage Activity (Joint)
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Van Horne Ballroom A-B
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Peter J. Murray,
St. Jude Children's Research Hospital
Cytokine-Mediated Deactivation of the Activated Macrophage
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Gerald Krystal,
British Columbia Cancer Research Center
The Role of SHIP in Macrophage Skewing and Activation
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*
Christopher K. Glass,
University of California, San Diego
Nuclear Receptor Repression Pathways that Regulate Inflammation
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Tim Ian Smallie,
Kennedy Institute of Rheumatology Division
Short Talk: IL-10 Negatively Regulates Macrophage Activation by Inhibiting Transcription Elongation
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Mezzanine 2
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7:30 - 10:00 PM
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Poster Session 3
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Mezzanine 2
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| Tuesday, February 16 |
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7:00 - 8:00 AM
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Breakfast
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Mezzanine 2
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8:00 - 11:00 AM
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Macrophage and Pathogens II
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Van Horne Ballroom A-B
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*
Sabine Ehrt,
Weill Cornell Medical College
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De'Broski R. Herbert,
Cincinnati Children's Research Foundation
Alternatively Activated Macrophages Control Helminth-Driven Immunopathology
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Thomas A. Wynn,
National Institutes of Health
The Role of IL-4/IL-13 Activated Macrophages in Fibrosis
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Judith E. Allen,
University of Edinburgh
The Macrophage and the Worm
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Sara R. Cherry,
University of Pennsylvania School of Medicine
Using high-throughput screening to identify cell-intrinsic innate immune pathways
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9:20 - 9:40 AM
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Coffee Break
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Van Horne Foyer
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11:00 AM -
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On Own for Lunch and Recreation
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4:30 - 5:00 PM
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Coffee Available
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Van Horne Foyer
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5:00 - 7:00 PM
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Metabolism and Macrophages at the Intersection of Metabolic Control (Joint)
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Van Horne Ballroom A-B
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*
Russell A. DeBose-Boyd,
University of Texas Southwestern Medical Center
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Ajay Chawla,
Stanford University Medical Center
Immune regulation of nutrient metabolism and aging
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William A. Muller,
Northwestern University Feinberg School of Medicine
All Roads Lead to the LBRC: A common mechanism for leukocyte transendothelial migration
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Ebru Erbay,
Harvard University School of Public Health
The Role of Endoplasmic Reticulum Stress in Atherosclerosis and its Regulation by Lipids
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Hwee Ying Lim,
National University of Singapore
Short Talk: Ezetimibe Restores lymphatic vessel function and dendritic cell migration, in hypercholesterolemic apoE deficient mice
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Mezzanine 2
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8:00 - 11:00 PM
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Entertainment
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Mezzanine 2
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| Wednesday, February 17 |
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Departure
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