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Angiogenesis in Health and Disease (X1)

Organizer(s): Michael Simons and William C. Sessa
February 28 - March 5, 2010
Keystone Resort  ·  Keystone, Colorado
Abstract Deadline: October 28, 2009
Late Abstract Deadline: November 30, 2009
Scholarship Deadline: October 28, 2009
Early Registration Deadline: December 28, 2009


Sponsored by ImClone Systems Corporation and Regulus Therapeutics, Inc.

Joint meeting: Cardiovascular Development and Repair (X2)
NOTE: Registration for meeting allows attendance at joint meeting (pending space availability).



This meeting took place in the 2010 season.

For a complete list of the meetings for the upcoming/current season,
see our meeting list, or search for a meeting.
Summary of Meeting
The Angiogenesis in Health and Disease meeting will assemble leaders in the most interesting and rapidly developing areas of vascular biology, including vascular development, arterial specification, miRs and neural guidance research. This meeting will emphasize the translational nature of research; a "clinical trials" session has been included in the program. We anticipate a highly interactive gathering of leaders in the field of angiogenesis.

Sunday, February 28
3:00 - 7:30 PM Registration Longs Peak Foyer
6:30 - 7:30 PM Refreshments Longs Peak Foyer
7:30 - 8:30 PM Keynote Address (Joint) Grays/Longs Peaks
* Michael Simons, Yale University
* Doris A. Taylor, University of Minnesota
Eric N. Olson, University of Texas Southwestern Medical Center at Dallas
MicroRNA Control of Cardiovascular Development and Disease
Monday, March 1
7:00 - 8:00 AM Breakfast Quandary Peak
8:00 - 11:00 AM Arterial Specification Grays Peak
* Eli Keshet, Hebrew University
Nathan Lawson, University of Massachusetts Medical School
Exploring Endothelial Diversity in the Zebrafish
Michael Simons, Yale University
Arterial Specification Signaling Cascade
Brian L. Black, University of California, San Francisco
A Combinatorial Transcriptional Code for Endothelial Development
Tao P. Zhong, Vanderbilt University
Regulation of Arterial-Venous Cell Specification and Migration
Xabier Lopez Aranguren, Katholieke Universiteit Leuven
Short Talk: The Nuclear Orphan Receptor COUP-TFII Plays an Essential Role in Establishing and Maintaining Venous and Lymphatic Endothelial Identity by Distinct Mechanisms
9:20 - 9:40 AM Coffee Break Longs Peak Foyer
11:00 AM - On Own for Lunch and Recreation
11:00 AM - 1:00 PM Poster Setup Quandary Peak
1:00 - 10:00 PM Poster Viewing Quandary Peak
4:30 - 5:00 PM Coffee Available Longs Peak Foyer
5:00 - 7:00 PM Vascular Metabolomics Grays Peak
* Kenneth Walsh, Boston University School of Medicine
Ulf P.E. Eriksson, Karolinska Institutet
Vascular Endothelial Growth Factor B Controls Endothelial Fatty Acid Uptake - Implications in Fatty Acid Metabolism
Frank J. Giordano, Yale University
Role of HIFs in Metabolic Regulation
Stéphane E. Germain, INSERM
Short Talk: Protection Against Myocardial Infarction through Preservation of Vascular Endothelial Cell Barrier Integrity and Reduction of No-Reflow by Angiopoietin-like 4
7:00 - 8:00 PM Social Hour w/ Lite Bites Quandary Peak
7:30 - 10:00 PM Poster Session 1 Quandary Peak
Tuesday, March 2
7:00 - 8:00 AM Breakfast Quandary Peak
8:00 - 11:15 AM Endothelial Cell-Tissue Interactions Grays Peak
* Nathan Lawson, University of Massachusetts Medical School
Eli Keshet, Hebrew University
On-Site Education by VEGF of Recruited Monocytes
Kenneth Walsh, Boston University School of Medicine
Paracrine Endothelium-Myocyte Interactions
Didier Y. R. Stainier, University of California, San Francisco
Endothelial Cell-Tissue Interactions during Zebrafish Organogenesis
Maija Bry, University of Helsinki
VEGF-B Induces VEGFR-1 and Bmx Tyrosine Kinase-Mediated Cardiac Hypertrophy and Strong Coronary Arteriogenesis in Rats
Christiana Ruhrberg, University College London
Macrophages Act as Cellular Chaperones for Vascular Anastomosis
9:20 - 9:40 AM Coffee Break Longs Peak Foyer
11:15 AM - On Own for Lunch and Recreation
11:15 AM - 1:00 PM Poster Setup Quandary Peak
1:00 - 10:00 PM Poster Viewing Quandary Peak
4:30 - 5:00 PM Coffee Available Longs Peak Foyer
5:00 - 7:00 PM Vascular Development and Collaterals Grays Peak
* Michael Simons, Yale University
Anne C. Eichmann, College de France
Development of Collaterals
James E. Faber, University of North Carolina, Chapel Hill
Development and Genetics of Collateral Formation and Remodeling
Eleni Tzima, University of North Carolina
A Novel Polarity Complex that Regulates Redox Signaling in Response to Fluid Stress
Suk-Won Jin, University of North Carolina Chapel Hill
Short Talk: Heterogeneity of Developing Vessels: A Unique Role for BMP in Developing Veins
7:00 - 8:00 PM Social Hour w/ Lite Bites Quandary Peak
7:30 - 10:00 PM Poster Session 2 Quandary Peak
Wednesday, March 3
7:00 - 8:00 AM Breakfast Quandary Peak
8:00 - 11:00 AM Cardiovascular Genetics (Joint) Grays/Longs Peaks
* William C. Sessa, Yale University School of Medicine
* Brian H. Annex, University of Virginia
Elizabeth M. McNally, University of Chicago
Dissecting Modifier Genes for Heart and Muscle Disease
Arya Mani, Yale University
The Genetic Link between Coronary Artery Disease and Metabolic Risk Factors
Calum A. MacRae, Brigham & Women's Hospital
Genetic Basis of Atrial Fibrillation
Jonathan G. Seidman, Harvard Medical School
Genetic Mechanisms of Hypertrophic Cardiomyopathy
Christian Kupatt, University of Munich
Short Talk: Pathophysiological Consequences of Chronic Endothelial Angiopoietin-2 Overexpression
9:20 - 9:40 AM Coffee Break Longs Peak Foyer
11:00 AM - On Own for Lunch and Recreation
11:00 AM - 1:00 PM Poster Setup Quandary Peak
1:00 - 10:00 PM Poster Viewing Quandary Peak
4:30 - 5:00 PM Coffee Available Longs Peak Foyer
5:00 - 7:15 PM Micro RNAs in the Endothelium Grays Peak
* Anne C. Eichmann, College de France
William C. Sessa, Yale University School of Medicine
Regulation of Vascular Function by miRNAs
Ralf H. Adams, Max-Planck-Institute for Molecular Biomedicine
Molecular Regulation of the Angiogenic Endothelial Phenotype
Jason E. Fish, Gladstone Institute
Short Talk: A Novel Slit/Robo/microRNA-218 Signaling Axis Regulates VEGF-Mediated Endocardial Migration and Heart Tube Formation
Amparo Acker-Palmer, University Frankfurt
EphrinB2 Regulates VEGFR2 Function in Developmental and Tumour Angiogenesis
7:15 - 8:00 PM Social Hour w/ Lite Bites Quandary Peak
7:30 - 10:00 PM Poster Session 3 Quandary Peak
Thursday, March 4
7:00 - 8:00 AM Breakfast Quandary Peak
8:00 - 11:00 AM Therapeutic Interventions Grays Peak
* Frank J. Giordano, Yale University
John Martin, University College London
Gene Therapy or Stem Cell Therapy: Which is the Future for Angiogenesis
Ryan J. Watts, Genentech, Inc.
Antibodies Targeting Vascular and Neuronal Pathways: Understanding Antibodies and the BBB
Donald M. McDonald, University of California, San Francisco
Angiogenesis Inhibitors: Risk and Return
Victor Kotelianski, Alnylam Pharmaceuticals Inc.
Development of RNAi Therapeutics
Kory J. Lavine, Washington University School of Medicine
Short Talk: Hedgehog Signaling in Coronary Development, Growth, and Disease
9:20 - 9:40 AM Coffee Break Longs Peak Foyer
11:00 AM - On Own for Lunch and Recreation
4:30 - 5:00 PM Coffee Available Longs Peak Foyer
5:00 - 7:00 PM Phospholipid Signaling and Late-Breaking Science Grays Peak
* Donald M. McDonald, University of California, San Francisco
Timothy T. Hla, Weill Medical College of Cornell University
S1P Signaling in the Vascular System
Mariona Graupera, Institut d´Investigació Biomèdica de Bellvitge
PI3K Signaling in Angiogenesis
Masahiro Murakami, Yale University School of Medicine
Short Talk:
John Chappell, University of North Carolina
Short Talk: A Novel Form of Vessel Sprout Guidance Requires Soluble Flt-1 (VEGFR-1)
Lydia S. Glaw, University of Virginia
Short Talk: PDGF-B Produced by Bone Marrow-Derived Cells Is Required for Normal Perivascular Coverage after Hypoxia-Induced Angiogenesis
7:00 - 8:00 PM Social Hour w/ Lite Bites Quandary Peak
8:00 - 11:00 PM Entertainment Quandary Peak
Friday, March 5
Departure
*Session Chair   †Speaker invited, not yet responded.



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