Keystone Symposia
Home | My Account | Shopping Cart  0
  Advanced
     facebook  twitter
Meeting Details  Printer Version   Meeting Search   Contact Us

Molecular Basis for Biological Membrane Organization and Dynamics (A5)

Organizer(s): Tom A. Rapoport and Sandra L. Schmid
January 10 - 15, 2010
Snowbird Resort  ·  Snowbird, Utah
Abstract Deadline: September 16, 2009
Late Abstract Deadline: October 13, 2009
Scholarship Deadline: September 16, 2009
Early Registration Deadline: November 10, 2009


Supported by The Directors' Fund



This meeting took place in the 2010 season.

For a complete list of the meetings for the upcoming/current season,
see our meeting list, or search for a meeting.
Summary of Meeting
Cellular membrane biology is a major area of research. Membrane proteins function as receptors, ion channels, or transporters, while the lipids provide not just a barrier between aqueous compartments, but also serve as signals. Lipids and proteins combine in as yet not fully understood ways to establish and maintain membrane organization and specific membrane domains. This meeting will address major questions in membrane biology that remain unanswered, including the structure of membrane proteins (we only know ~100 structures, but 25% of all proteins are membrane proteins!), the mechanisms driving membrane organization and curvature, mechanisms of organellar biogenesis and the transport between organelles, and how membranes undergo fusion and fission. In addition, the meeting will cover emerging techniques. A major goal of the meeting is to bring together cell biologists, biophysicists and theoretical biologists, which in the past had little interaction.

Sunday, January 10
3:00 - 7:30 PM Registration Ballroom Lobby
6:30 - 7:30 PM Refreshments Ballroom Lobby
7:30 - 8:30 PM Keynote Address Ballroom 2-3
* Tom A. Rapoport, Harvard University Medical School
Randy W. Schekman, University of California, Berkeley
Mechanism of Transport Vesicle Budding and Cargo Sorting
Monday, January 11
7:00 - 8:00 AM Breakfast Golden Cliff/Eagles Nest
8:00 - 11:45 AM Membrane Protein Structure Ballroom 2-3
* Randy W. Schekman, University of California, Berkeley
Poul Nissen, Aarhus University
Structure and Function of the P-ATPase Ion Pumps
Jue Chen, Purdue University
Alternating Access of the Maltose Transporter
Thomas Wollert, National Institutes of Health
Short Talk: Molecular Mechanism for Multivesicular Body Biogenesis by the ESCRT Complexes
Ramanujan S. Hegde, NICHD, National Institutes of Health
Mechanisms of Membrane Protein Insertion into the ER
Roland Beckmann, University of Munich
Lessons from EM Structures of Ribosome-Translocon Complexes
Thomas U. Schwartz, Massachusetts Institute of Technology
Structural Commonalities between the Lattice Scaffolds of Vesicle Coats and the Nuclear Pore Complex
Kyle D. Brewer, University of Texas Southwestern Medical Center
Short Talk: NMR Analysis of Synaptotagmin-1 on Nanodiscs
9:20 - 9:40 AM Coffee Break Ballroom Lobby
11:45 AM - On Own for Lunch and Recreation
11:45 AM - 1:00 PM Poster Setup Superior/Wasatch/Maybird
1:00 - 10:00 PM Poster Viewing Superior/Wasatch/Maybird
4:30 - 5:00 PM Coffee Available Ballroom Lobby
5:00 - 7:00 PM Membrane Curvature in Vesicle Building Ballroom 2-3
* Kai Simons, Max Planck Institute of Molecular Cell Biology and Genetics
Harvey T. McMahon, MRC Laboratory of Molecular Biology
Sculpting Clathrin-Coated Vesicles
Beverly Wendland, Johns Hopkins University
A New Family of Endocytic Adaptor Proteins Coordinates Membrane and Actin Dynamics
Gregory A. Voth, University of Utah
Short Talk: Multiscale Computer Simulation of Membrane Remodelling by Proteins
Bruno Antonny, Institut de Pharmacologie Moleculaire et Cellulaire
Sensing Membrane Curvature with ALPS Motifs
7:00 - 8:00 PM Social Hour w/ Lite Bites Superior/Wasatch/Maybird
7:30 - 10:00 PM Poster Session 1 Superior/Wasatch/Maybird
Tuesday, January 12
7:00 - 8:00 AM Breakfast Golden Cliff/Eagles Nest
8:00 - 11:15 AM Shaping Organelles Ballroom 2-3
* Sandra L. Schmid, The Scripps Research Institute
Jodi Ina Nunnari, University of California, Davis
How Mitochondria Divide and Fuse
Robert G. Parton, University of Queensland
New Insights into Caveola Formation and Function
Gia Voeltz, University of Colorado, Boulder
Shaping the Tubular ER
Michael Kozlov, Tel Aviv University
Theory of Membrane Shaping and Remodeling by Proteins
Yoko Shibata, Harvard Medical School/HHMI
Short Talk: A Class of Dynamin-like GTPases Involved in the Generation of the Tubular ER Network
James A. McNew, Rice University
Short Talk: Characterization of Atlastin-Mediated Fusion in vitro
9:20 - 9:40 AM Coffee Break Ballroom Lobby
11:15 AM - On Own for Lunch and Recreation
11:15 AM - 1:00 PM Poster Setup Superior/Wasatch/Maybird
1:00 - 10:00 PM Poster Viewing Superior/Wasatch/Maybird
4:30 - 5:00 PM Coffee Available Ballroom Lobby
5:00 - 7:00 PM Functional Organization of Membrane Domains I Ballroom 2-3
* Joshua Zimmerberg, National Institutes of Health
Patricia Bassereau, Institut Curie
Physical Aspects of Lipid and Protein Sorting
Deborah A. Brown, Stony Brook University
Caveolin-1-Induced Membrane Tubules in Human Breast Cancer Cells
Tobias Meyer, Stanford University Medical Center
Ca2+ signaling and ER-PM junctions
Donatienne Tyteca, Université Catholique de Louvain
Short Talk: Three Unrelated Sphingomyelin Analogs Spontaneously Cluster into Plasma Membrane Micrometric Domains
7:00 - 8:00 PM Social Hour w/ Lite Bites Superior/Wasatch/Maybird
7:30 - 10:00 PM Poster Session 2 Superior/Wasatch/Maybird
Wednesday, January 13
7:00 - 8:00 AM Breakfast Golden Cliff/Eagles Nest
8:00 - 11:15 AM Functional Organization of Membrane Domains II Ballroom 2-3
* Patricia Bassereau, Institut Curie
Phyllis I. Hanson, Washington University School of Medicine
ESCRTs and Membrane Domains
Kai Simons, Max Planck Institute of Molecular Cell Biology and Genetics
Lipid–Protein Interactions Governing Raft Partitioning in Membranes
Sandra L. Schmid, The Scripps Research Institute
Dynamin-Mediated Membrane Fission
Sarah L. Veatch, Cornell University
Short Talk: Correlation Function Analysis Corrects Artifactual Self-Clustering and Reveals Significant Co-Localization of FcepsilonRI and Lyn in Resting RBL-2H3 Mast Cells
Joshua Zimmerberg, National Institutes of Health
Membrane Morphological Transformations in Models for Exocytosis and Endocytosis
Dylan M. Owen, University of New South Wales
Short Talk: PALM Microscopy and Cluster Analysis of Raft and Non-Raft Proteins
9:20 - 9:40 AM Coffee Break Ballroom Lobby
11:15 AM - On Own for Lunch and Recreation
11:15 AM - 1:00 PM Poster Setup Superior/Wasatch/Maybird
1:00 - 10:00 PM Poster Viewing Superior/Wasatch/Maybird
4:30 - 5:00 PM Coffee Available Ballroom Lobby
5:00 - 7:00 PM Lipid Transport and Organelle Transport Ballroom 2-3
* William T. Wickner, Dartmouth Medical School
* Randy W. Schekman, University of California, Berkeley
Dennis R. Voelker, National Jewish Medical and Research Center
Protein and Lipid Complexes Regulating Aminoglycerophospholipid Transport in Eukaryotes
William A. Prinz, NIDDK, National Institutes of Health
Lipid-Regulated Sterol Transfer Between Closely Apposed Membranes by Oxysterol-Binding Protein Homologs
Gerrit van Meer, Utrecht University
Sphingolipid Dynamics and Membrane Protein Function
Tobias C. Walther, Max-Planck Institute for Biochemistry
Short Talk: Mechanism of Plasma Membrane Organization by Eisosomes
7:00 - 8:00 PM Social Hour w/ Lite Bites Superior/Wasatch/Maybird
7:30 - 10:00 PM Poster Session 3 Superior/Wasatch/Maybird
Thursday, January 14
7:00 - 8:00 AM Breakfast Golden Cliff/Eagles Nest
8:00 - 11:15 AM Mechanisms Governing Membrane Fusion and Fission Ballroom 2-3
* Michael Kozlov, Tel Aviv University
William T. Wickner, Dartmouth Medical School
Mechanisms of Yeast Homotypic Vacuole Fusion
Stephen G. Sligar, University of Illinois at Urbana-Champaign
Elucidating the Structure and Function of Membrane Proteins through Nanotechnology
Josep Rizo, University of Texas Southwestern Medical Center
Synaptic Vesicle Fusion
Marta K. Domanska, University of Virginia, School of Medicine
Short Talk: Fast Single Vesicle SNARE-Mediated Membrane Fusion Assay in Planar Supported Bilayers Reveals Details about Fusion Mechanism
Yoshinori Ohsumi, Tokyo Institute of Technology
Molecular Machinery for Autophagosome Formation
Eric G. Bend, University of Utah
Short Talk: Unc18 and SNARE Interactions during Vesicle Fusion
9:20 - 9:40 AM Coffee Break Ballroom Lobby
11:15 AM - On Own for Lunch and Recreation
4:30 - 5:00 PM Coffee Available Ballroom Lobby
5:00 - 7:15 PM Membrane Dynamics in Endocytosis Ballroom 2-3
* Harvey T. McMahon, MRC Laboratory of Molecular Biology
Matthew N.J. Seaman, University of Cambridge
Retromer-Mediated Endosome-to-Golgi Retrieval
David G. Drubin, University of California, Berkeley
A Yeast Killer Toxin Screen Provides Insights into A/B Toxin Entry, Trafficking and Killing Mechanisms
Emanuele Cocucci, Immune Disease Institute, Harvard Medical School
Short Talk: The First 2 Seconds in the Life of a Clathrin Coated Pit
Min Wu, Yale School of Medicine
Short Talk: Synergistic Action of Clathrin and Membrane Tubulation in a Cell Free System
8:00 - 9:00 PM Social Hour w/ Lite Bites Ballroom 1-2
8:00 - 11:00 PM Entertainment Ballroom 1-2
Friday, January 15
Departure
*Session Chair   †Speaker invited, not yet responded.



© 2010 Keystone Symposia on Molecular and Cellular Biology. All Rights Reserved.
Terms of Use | Privacy Policy | Site Map

Keystone Symposia is a 501(c)(3) non-profit organization directed and supported by the scientific community.

Phone: +1 (800) 253-0685 or +1 (970) 262-1230
Fax: +1 (970) 262-1525
info@keystonesymposia.org