| Monday, April 12 |
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3:00 - 7:30 PM
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Registration
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Foyer
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6:30 - 7:30 PM
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Refreshments
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Foyer
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7:30 - 9:30 PM
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Keynote Session (Joint)
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Sea to Sky Ballroom B,C
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*
Juleen R. Zierath,
Karolinska Institutet
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Victor R. Ambros,
University of Massachusetts
MicroRNAs in Model Systems and Human Disease
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*
Markus Stoffel,
Institut f. Molekulare Systembiologie
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Jennifer A. Lippincott-Schwartz,
NICHD, National Institutes of Health
Mitochondrial Role in Cell Cycle Control and Autophagy
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| Tuesday, April 13 |
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7:00 - 8:00 AM
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Breakfast
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Sea to Sky Ballroom A, Lower Level
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8:00 - 11:15 AM
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Genetics of Diabetes
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Sea to Sky Ballroom C
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*
Simeon I. Taylor,
Bristol-Myers Squibb Company
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Philippe Froguel,
Imperial College of London
Genome Structure and Point DNA Variation: The Power of the Extreme in Diabesity
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Mark I. McCarthy,
Churchhill Hospital
Type 2 Diabetes: Susceptibility Variants across the Allele Frequency Spectrum
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Jose C. Florez,
Massachusetts General Hospital
Genetic Epidemiology of Type 2 Diabetes and Related Traits in General Populations
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Eric Schadt,
Pacific Biosciences
Multi-Tissue Networks Elucidate Type 2 Diabetes Circuits
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Jussi A. Pihlajamäki,
Kuopio University Hospital
Short Talk: Alternative Splicing is Regulated by Weight Loss and Differs between Fat Depots in Humans
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Jeremy B.M. Jowett,
Baker IDI Heart and Diabetes Institute
Short Talk: Expression Profiling Identifies Biomarkers for Progression to Type 2 Diabetes
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9:20 - 9:40 AM
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Coffee Break
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Foyer
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11:15 AM -
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On Own for Lunch and Recreation
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11:15 AM - 1:00 PM
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Poster Setup
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Foyer/Mountain View/Sea to Sky Ballroom A
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1:00 - 10:00 PM
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Poster Viewing
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Foyer/Mountain View/Sea to Sky Ballroom A
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4:30 - 5:00 PM
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Coffee Available
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Foyer
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5:00 - 7:00 PM
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Cell and Tissue Signaling Mechanisms in Diabetes
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Sea to Sky Ballroom C
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*
Adria Giacca,
University of Toronto
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†,
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Claire C. Bastie,
Albert Einstein College of Medicine
Fyn Kinase and LKB1: A Novel Pathway Regulating Lipid Utilization and Energy Expenditure
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Robert E. Lewis,
University of Nebraska Medical Center
Molecular Scaffolds as Energy Sensors
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Bei B. Zhang,
Merck Research Laboratories
Modulation of Glucose, Amino Acid and Lipid Metabolism Pathways with Pharmacological Agents
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Philipp Gut,
University of California, San Francisco
Short Talk: In vivo Drug Discovery of New Regulators of Glucose Metabolism using Transgenic “Gluconeogenesis Reporter” Zebrafish
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Foyer/Mountain View/Sea to Sky Ballroom A
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7:30 - 10:00 PM
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Poster Session 1
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Foyer/Mountain View/Sea to Sky Ballroom A
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| Wednesday, April 14 |
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7:00 - 8:00 AM
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Breakfast
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Sea to Sky Ballroom A, Lower Level
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8:00 - 11:15 AM
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Intertissue Communication
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Sea to Sky Ballroom C
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*
Jeffrey S. Elmendorf,
Indiana University School of Medicine
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Barbara B. Kahn,
Beth Israel Deaconess Medical Center
A Novel Pathway in Adipose Tissue and Liver that Regulates Adiposity
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Kenneth Walsh,
Boston University School of Medicine
Discovery of Novel Myokines
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Philipp E. Scherer,
University of Texas Southwestern Medical Center at Dallas
Discovery of Novel Adipokines
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Fatima Bosch,
Universitat Autonoma Barcelona
Gene Therapy and Diabetes
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Tsu-Shuen Tsao,
University of Arizona
Short Talk: Inhibition of Adiponectin Oligomerization under Oxidizing Conditions and Induction of an Oxidizing Redox Environment in Endoplasmic Reticulum of 3T3-L1 Adipocytes Exposed to High Concentrations of Palmitate
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Marianna Sadagurski,
Children's Hospital, Harvard Medical School
Short Talk: Inactivation of Foxo1 in Leptin Receptor (LepRb)-Expressing Neurons Reverses Obesity and Diabetes, Caused by Deletion of Insulin Receptor Substrate 2 (Irs2)
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9:20 - 9:40 AM
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Coffee Break
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Foyer
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11:15 AM -
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On Own for Lunch and Recreation
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11:15 AM - 1:00 PM
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Poster Setup
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Foyer/Mountain View/Sea to Sky Ballroom A
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1:00 - 10:00 PM
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Poster Viewing
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Foyer/Mountain View/Sea to Sky Ballroom A
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4:30 - 5:00 PM
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Coffee Available
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Foyer
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5:00 - 7:15 PM
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Molecular Mechanisms in Insulin Secretion and Action (Joint)
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Sea to Sky Ballroom B,C
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*
Barbara B. Kahn,
Beth Israel Deaconess Medical Center
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C. Ronald Kahn,
Joslin Diabetes Center
Insulin Signaling and Insulin Resistance: The Ultimate Systems Biology Problem
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Per-Olof Berggren,
Karolinska Institutet
Systems Biology Approach to Study Beta Cell Function and Survival
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Morris J. Birnbaum,
University of Pennsylvania
The Role of Akt in the Regulation of Hepatic Metabolism by Insulin
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Weiping Han,
Singapore Bioimaging Consortium
Short Talk: Molecular Regulation of Calcium-Dependent Insulin Secretion
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Jennifer L. Estall,
Dana-Farber Cancer Institute - Harvard Medical School
Short Talk: PGC-1alpha Negatively Regulates Hepatic FGF21 Expression by Modulating the Heme/Rev-Erbalpha Axis
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7:15 - 8:15 PM
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Social Hour w/ Lite Bites
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Foyer/Mountain View/Sea to Sky Ballroom A
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7:30 - 10:00 PM
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Poster Session 2
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Foyer/Mountain View/Sea to Sky Ballroom A
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| Thursday, April 15 |
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7:00 - 8:00 AM
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Breakfast
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Sea to Sky Ballroom A, Lower Level
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7:00 - 11:00 AM
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Poster Setup
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Foyer/Mountain View/Sea to Sky Ballroom A
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8:00 - 11:15 AM
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Inflammatory Mechanisms and Insulin Resistance
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Sea to Sky Ballroom C
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*
Nancy A. Thornberry,
Merck Research Laboratories
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Diane J. Mathis,
Harvard Medical School
Lymphocyte Regulation of Adipose Tissue Inflammation
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Roger J. Davis,
University of Massachusetts Medical School
Pathogenesis Mechanisms of the JNK Pathway
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Remy G. Burcelin,
Institute of Molecular Medicine
Intestinal Microflora, Inflammation, and Metabolic Diseases
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Michael P. Czech,
University of Massachusetts Medical School
RNAi-Based Strategies to Address Metabolic Dysfunction
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Birgitte Lindegaard,
Rigshospitalet
Short Talk: IL-18 Increases Intramuscular Fat Oxidation by Activating AMPK
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Heather C. Denroche,
University of British Columbia
Short Talk: Leptin Therapy Reverses Fasting Hyperglycemia and Enhances Insulin Sensitivity in Diabetic Mice, Independent of Hepatic Leptin Signaling
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9:20 - 9:40 AM
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Coffee Break
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Foyer
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11:00 AM - 5:00 PM
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Poster Viewing
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Foyer/Mountain View/Sea to Sky Ballroom A
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11:30 AM - 12:30 PM
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Lunch
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Foyer/Mountain View/Sea to Sky Ballroom A
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12:30 - 2:30 PM
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Poster Session 3
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Foyer/Mountain View/Sea to Sky Ballroom A
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4:30 - 5:00 PM
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Coffee Available
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Foyer
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5:00 - 7:15 PM
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Emerging Targets for Improving Insulin Action and Secretion (Joint)
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Sea to Sky Ballroom B,C
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*
C. Ronald Kahn,
Joslin Diabetes Center
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Richard D. DiMarchi,
Indiana University
Novel Glucagon-Like Chimera Peptides – Virtues of Combinatorial Pharmacology
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David E. Moller,
Eli Lilly and Company
Challenges and Opportunities for Diabetes Drug Discovery
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Johan Auwerx,
École Polytechnique Fédérale de Lausanne
Integrating Metabolic Control by NAD+ Sensors
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Tian Q. Sun,
Rigel Inc.
Short Talk: Small Molecule Adiponectin Mimetics Improve Hepatic Steatosis and Insulin Sensitivity in Diabetic Mouse Models
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Christine Esau,
Regulus Therapeutics
Short Talk: Inhibition of Let-7 with Anti-miR Oligonucleotides Improves Insulin Resistance in DIO Mice
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7:15 PM -
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On Own for Dinner
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| Friday, April 16 |
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7:00 - 8:00 AM
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Breakfast
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Sea to Sky Ballroom A, Lower Level
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8:00 - 11:15 AM
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Insulin Secretion and Action in Humans (Joint)
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Sea to Sky Ballroom B,C
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*
Michael P. Czech,
University of Massachusetts Medical School
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Andrew Hattersley,
Peninsula Medical School
Learning from Genetic Beta Cell Defects in Man
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Anna Moore,
Massachusetts General Hospital
Imaging Pancreatic Islets in vivo: Current Status
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Juleen R. Zierath,
Karolinska Institutet
Gene/Environment Influence on Skeletal Muscle Insulin Sensitivity in Type 2 Diabetic Patients
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Peter Arner,
Karolinska Institute
Dysfunction in Human Adipose Tissue and Insulin Resistance
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Michael Ristow,
University of Jena
Short Talk: Impaired Insulin Signaling Extends Life Span by Increasing Oxidative Stress
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Mary Armanios,
Johns Hopkins School of Medicine
Short Talk: Short Telomeres Lead to beta-cell Dysfunction and Impair Glucose Tolerance
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9:20 - 9:40 AM
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Coffee Break
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Foyer
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11:00 AM -
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On Own for Lunch and Recreation
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4:30 - 5:00 PM
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Coffee Available
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Foyer
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5:00 - 7:00 PM
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Type 2 Diabetes in Children and Adolescents
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Sea to Sky Ballroom C
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*
Philippe Froguel,
Imperial College of London
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Rebecca Anne Simmons,
University Pennsylvania School of Medicine
Epigenetic Mechanisms in the Development of Type 2 Diabetes
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Susan Ozanne,
University of Cambridge
Early Life Programming of Type 2 Diabetes
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Phil Zeitler,
University of Colorado, Denver
Type 2 Diabetes in Children and Adolescents: Epidemiology, Pathophysiology, and Comorbidities
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Kasper Rud,
University of Copenhagen
Short Talk: Effects of Gestational Low Protein Diet Followed by Postnatal High Fat or High Sucrose Diet on the Interplay between Fat and Carbohydrate Metabolism in Rat Mitochondria
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Foyer/Mountain View/Sea to Sky Ballroom A
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8:00 - 11:00 PM
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Entertainment
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Foyer/Mountain View/Sea to Sky Ballroom A
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| Saturday, April 17 |
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Departure
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