| Wednesday, April 7 |
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3:00 - 7:30 PM
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Registration
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Lower Atrium
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6:30 - 7:30 PM
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Refreshments
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Lower Atrium
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7:30 - 8:30 PM
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Keynote Address
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Gallatin
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*
Karen Adelman,
NIEHS, National Institutes of Health
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Richard A. Young,
Whitehead Institute for Biomedical Research
Programming Embryonic Stem Cell State
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| Thursday, April 8 |
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7:00 - 8:00 AM
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Breakfast
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Jefferson/Madison
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8:00 - 11:00 AM
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Genomic Approaches to Understanding Gene Expression
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Gallatin
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*
Marc Timmers,
University Medical Centre Utrecht
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Jonathan Widom,
Northwestern University
DNA-Encoded Nucleosome Organization of Eukaryotic Genomes
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Steven Henikoff,
Fred Hutchinson Cancer Research Center
Mapping Genome-Wide Nucleosome Dynamics
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B. Franklin Pugh,
Pennsylvania State University
Global Interplay between the Transcription Machinery and Chromatin
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Frank C.P. Holstege,
University Medical Center, Utrecht
Understanding Regulatory Circuitry through Expression-Profile Phenotypes
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W. Lee Kraus,
Cornell University
Short Talk: Exploring the Direct Estrogen-Regulated Transcriptome in Breast Cancer Cells Using GRO-Seq
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9:20 - 9:40 AM
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Coffee Break
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Lower Atrium
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11:00 AM -
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On Own for Lunch and Recreation
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11:00 AM - 1:00 PM
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Poster Setup
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Jefferson/Madison
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1:00 - 10:00 PM
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Poster Viewing
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Jefferson/Madison
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4:30 - 5:00 PM
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Coffee Available
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Lower Atrium
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5:00 - 7:00 PM
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Transcription Regulation in Stem Cells and during Development
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Gallatin
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*
Richard A. Young,
Whitehead Institute for Biomedical Research
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Michael S. Levine,
University of California, Berkeley
Gene Activation during Development and Differentiation in Drosophila
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Fiona M. Watt,
CRUK Cambridge Research Institute
Proliferation and Differentiation of Epidermal Stem Cells
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Kenneth S. Zaret,
University of Pennsylvania
Pioneer Transcription Factors in Programming of Liver and Pancreas Progenitors: Lessons for Stem Cell Differentiation
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Xiaole Shirley Liu,
Dana Farber Cancer Institute, Harvard School of Public Health
Short Talk: Using Histone Mark Dynamics to Infer the Transcription Regulatory Network in Intestine Development
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Jefferson/Madison
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7:30 - 10:00 PM
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Poster Session 1
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Jefferson/Madison
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| Friday, April 9 |
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7:00 - 8:00 AM
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Breakfast
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Jefferson/Madison
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8:00 - 11:00 AM
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Transcription Regulation - From Pol II Recruitment to Early Elongation
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Gallatin
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*
Kenneth S. Zaret,
University of Pennsylvania
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Robert G. Roeder,
Rockefeller University
Function of Diverse Transcriptional Coactivators in Animal Cells
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Marc Timmers,
University Medical Centre Utrecht
Dynamic Regulation of the Basal Transcription Machinery
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Jennifer F. Kugel,
University of Colorado, Boulder
Regulation of Early Steps of Transcription by ncRNAs
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Bijan Sobhian,
Institute of Human Genetics
Short Talk: HIV-1 Tat Assembles a Multifunctional Transcription Elongation Complex and Stably Associates with the 7SK snRNP
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Laszlo Tora,
Institut de Genetique et de Biologie Moleculaire et Cellulaire
TBP2 is Essential for Germ Cell Development by Regulating Transcription and Chromatin Condensation in the Oocyte
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9:20 - 9:40 AM
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Coffee Break
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Lower Atrium
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11:00 AM -
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On Own for Lunch and Recreation
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11:00 AM - 1:00 PM
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Poster Setup
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Jefferson/Madison
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1:00 - 10:00 PM
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Poster Viewing
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Jefferson/Madison
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2:30 - 4:30 PM
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Workshop 1: Genomic Approaches: Discovery of Transcription Modulators as Drug Targets and High-Throughput Techniques for Investigating Changes in Gene Expression
This workshop is designed to engage members of pharmaceutical industry using new techniques to identify transcription inhibitors, as well as companies that do high-throughput sequencing.
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Gallatin
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*
Laszlo Tora,
Institut de Genetique et de Biologie Moleculaire et Cellulaire
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James E. Bradner,
Dana-Farber Cancer Institute
Direct Inhibition of the Notch Transcription Factor Complex
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Jun Zhu,
Institute for Genome Sciences & Policy
The Landscape of Transcription Initiation in the Drosophila melanogaster Embryo
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Tae-Kyung Kim,
University of Texas Southwestern Medical Center
Widespread Transcription at Thousands of Enhancers during Activity-Dependent Gene Expression in Neurons
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Marta Radman-Livaja,
University of Massachusetts Medical School
Gene Inactivation and Epigenetic Inheritance
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Michael P. Schnetz,
Case Western Reserve University
CHD7 Targets Active Gene Enhancer Elements to Modulate ES Cell-Specific Gene Expression
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Michael D. Wilson,
Cambridge Research Institute
Five Vertebrate ChIP-seq Reveals the Genetic Mechanisms of Rapid Transcription Factor Binding Divergence
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4:30 - 5:00 PM
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Coffee Available
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Lower Atrium
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5:00 - 7:00 PM
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Regulation of Transcription Elongation
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Gallatin
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*
John T. Lis,
Cornell University
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Hiroshi Handa,
Tokyo Institute of Technology
The Role of Transcription Elongation Factors in Genome Expression
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Karen Adelman,
NIEHS, National Institutes of Health
Pol II Stalling Across the Genome
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David S. Gilmour,
Pennsylvania State University
Biochemical and in vivo Analysis of Promoter Proximal Pausing
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Ryan Baugh,
Duke University
Short Talk: Nutritional Control of Pol II Pausing during C. elegans Development
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Jefferson/Madison
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7:30 - 10:00 PM
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Poster Session 2
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Jefferson/Madison
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| Saturday, April 10 |
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7:00 - 8:00 AM
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Breakfast
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Jefferson/Madison
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8:00 - 11:00 AM
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The Interplay between Transcription and Chromatin
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Gallatin
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*
Steven Henikoff,
Fred Hutchinson Cancer Research Center
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Jane Mellor,
University of Oxford
Histone Modifications, Transcription Factors, ncRNA and Gene Loops in Transcription
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Marc D. Meneghini,
University of Toronto
Short Talk: Global Histone Demethylation Controls Spore Differentiation Timing during Budding Yeast Gametogenesis
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Olivier Cuvier,
LBME- CNRS
Deciphering the Discrete Stages of Insulator-encoded Nucleosome-Positioning: The Road toward Transcriptional Competence
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Ali Shilatifard,
Stowers Institute for Medical Research
Transcriptional Elongation Control and Human Leukemia
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David H. Price,
University of Iowa
Mechanism of Release of P-TEFb and HEXIM1 from the 7SK snRNP by HIV Tat and the Chromatin Binding Protein, Brd4
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9:20 - 9:40 AM
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Coffee Break
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Lower Atrium
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11:00 AM -
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On Own for Lunch and Recreation
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11:00 AM - 1:00 PM
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Poster Setup
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Jefferson/Madison
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1:00 - 10:00 PM
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Poster Viewing
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Jefferson/Madison
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2:30 - 4:30 PM
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Workshop 2: New and Noteworthy
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Gallatin
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*
Joan W. Conaway,
Stowers Institute for Medical Research
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Maria Ciofani,
Skirball Institute of Biomolecular Medicine, NYUSOM
Transcriptional Regulatory Network Underlying CD4+ T Helper 17 (Th17) Lineage Specification
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Suming Huang,
University of Florida
Serine Phosphorylation on TAL1 Regulates its Interaction with Histone Demethylase LSD1 during Hematopoiesis
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Miguel Garcia-Diaz,
Stony Brook University
A Unique DNA Binding Mode Enables Human mterf1 to Regulate Mitochondrial Transcription
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Akihiko Yokoyama,
National Cancer Center Research Institute
Mechanisms of MLL-Dependent Transcriptional Maintenance in Normal and Cancer Cells
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Madeline M. Wong,
National Cancer Institute, NIH
Promoter Bound p300 Complexes Facilitate Transmission of Molecular Memory Across the Cell Cycle
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Ines de Santiago,
Medical Research Council - Clinical Sciences Centre
Genome-Wide Mapping of RNA Polymerase II Phosphorylation Elucidates the CTD Code in Embryonic Stem Cells
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4:30 - 5:00 PM
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Coffee Available
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Lower Atrium
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5:00 - 7:00 PM
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Activators and Co-Regulatory Complexes
|
Gallatin
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*
Katherine A. Jones†,
The Salk Institute
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Barbara Panning,
University of California, San Francisco
Tip60-p400 as a Regulator of Embryonic Stem Cell Identity
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Joan W. Conaway,
Stowers Institute for Medical Research
Mechanisms for Recruiting Chromatin Remodeling Complexes to Their Targets
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Susan E. Mango,
Harvard University
Investigating the Transcriptional Mechanisms that Govern the Progression of C. elegans Development
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Michael Meisterernst,
Institute of Molecular Tumor Biology
Short Talk: Transcription Cofactor PC4 is Critical for Cellular Proliferation and Early Development of Mammals
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Jefferson/Madison
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7:30 - 10:00 PM
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Poster Session 3
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Jefferson/Madison
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| Sunday, April 11 |
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7:00 - 8:00 AM
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Breakfast
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Jefferson/Madison
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8:00 - 11:00 AM
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Co-Transcriptional RNA Processing and Non-Coding RNAs
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Gallatin
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*
Wendy A. Bickmore,
MRC Human Genetics Unit
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Stephen Buratowski,
Harvard Medical School
Connecting Transcription to Chromatin and mRNA Processing
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Katherine A. Jones,
The Salk Institute
SKIP, a Cell Survival Factor that Controls Elongation and Gene-Specific Splicing
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Sukesh R. Bhaumik,
Southern Illinois University School of Medicine
Short Talk: A Novel Regulatory Pathway of Eukaryotic Transcriptional Activation by mRNA Cap-Binding Complex in vivo
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Ramin Shiekhattar,
Wistar Institute
Elucidating the Function of Long Non-Coding RNAs
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9:20 - 9:40 AM
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Coffee Break
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Lower Atrium
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4:30 - 5:00 PM
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Coffee Available
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Lower Atrium
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5:00 - 7:00 PM
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Imaging and Probing Global Nuclear Architecture
|
Gallatin
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*
Stephen Buratowski,
Harvard Medical School
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Bas van Steensel,
Netherlands Cancer Institute
Architecture and Function of Genome - Nuclear Lamina Interactions
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Wendy A. Bickmore,
MRC Human Genetics Unit
Ring1B Compacts Chromatin Structure, and Represses Gene Expression, Independent of Histone Ubiquitination
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Jie Yao,
Janelia Farm Resarch Campus/HHMI
Short Talk: Coordinate Re-Positioning of Genes and Core Promoter Selectivity Factors during Myogenesis
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John T. Lis,
Cornell University
New Views of Local and Genome-Wide Transcription Activation in Vivo
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7:00 - 7:15 PM
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Closing Remarks
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Marc Timmers,
University Medical Centre Utrecht
Closing Remarks
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7:15 - 8:15 PM
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Social Hour w/ Lite Bites
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Jefferson/Madison
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8:00 - 11:00 PM
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Entertainment
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Jefferson/Madison
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| Monday, April 12 |
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Departure
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