| Monday, April 12 |
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3:00 - 7:30 PM
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Registration
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Foyer
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6:30 - 7:30 PM
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Refreshments
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Foyer
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7:30 - 9:30 PM
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Keynote Session (Joint)
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Sea to Sky Ballroom B,C
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*
Juleen R. Zierath,
Karolinska Institutet
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Victor R. Ambros,
University of Massachusetts
MicroRNAs in Model Systems and Human Disease
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*
Markus Stoffel,
Institut f. Molekulare Systembiologie
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Jennifer A. Lippincott-Schwartz,
NICHD, National Institutes of Health
Mitochondrial Role in Cell Cycle Control and Autophagy
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| Tuesday, April 13 |
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7:00 - 8:00 AM
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Breakfast
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Sea to Sky Ballroom A, Lower Level
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8:00 - 11:00 AM
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From Stem Cell Development to Transplantation
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Sea to Sky Ballroom B
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*
Catherine Lee May,
Children Hospital of Philadelphia
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Bernhard J. Hering,
University of Minnesota
Islet Transplantation: Today and Tomorrow
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Anne Grapin-Botton,
Ecole Polytechnique Fédérale De Lausanne
Role of Pancreas 3D Architecture in Endocrine Cell Development
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Lori Sussel,
Columbia University
Regulation of Pancreatic Islet Cell Fates
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Maike Sander,
University of California, San Diego
Control of Cell Fate Choice in the Pancreas
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Dina Fomina,
Harvard University
Short Talk: Altering Pancreatic Cell State with Small Molecules
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9:50 - 10:10 AM
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Coffee Break
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Foyer
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11:00 AM -
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On Own for Lunch and Recreation
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11:00 AM - 1:00 PM
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Poster Setup
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Foyer/Mountain View/Sea to Sky Ballroom A
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1:00 - 10:00 PM
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Poster Viewing
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Foyer/Mountain View/Sea to Sky Ballroom A
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4:30 - 5:00 PM
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Coffee Available
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Foyer
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5:00 - 7:00 PM
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Signaling in Pancreatic B-Cells
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Sea to Sky Ballroom B
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*
Rohit N. Kulkarni,
Joslin Diabetes Center
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Eckhard Lammert,
Heinrich-Heinebetscholz
Role of Blood Vessels in Pancreatic Islet Development and Function
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Marc A. Prentki,
CRCHUM/Université de Montreal
Beta Cell Metabolic Signaling and Dysfunction in Type 2 Diabetes
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Ingo B. Leibiger,
Karolinska Institutet
Insulin Signaling in the Pancreatic Beta Cell
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Jocelyn E. Manning Fox,
University of Alberta
Short Talk: Small Ubiquitin-Like Modifier 1 (SUMO1) Directly and Acutely Regulates Insulin Exocytosis from Human beta-Cells
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Foyer/Mountain View/Sea to Sky Ballroom A
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7:30 - 10:00 PM
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Poster Session 1
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Foyer/Mountain View/Sea to Sky Ballroom A
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| Wednesday, April 14 |
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7:00 - 8:00 AM
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Breakfast
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Sea to Sky Ballroom A, Lower Level
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8:00 - 11:00 AM
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Transcriptional Networks Signaling
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Sea to Sky Ballroom B
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*
Maike Sander,
University of California, San Diego
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Catherine Lee May,
Children Hospital of Philadelphia
Islet-1 and its Cofactor Ldb1 in the Endocrine Pancreas
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Markus Stoffel,
Institut f. Molekulare Systembiologie
MicroRNA Networks
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Roland W. Stein,
Vanderbilt University Medical Center
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Alan D. Attie,
University of Wisconsin-Madison
Networks of QTLs, mRNAs, and microRNAs in Beta Cell Growth and Function
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Melissa Thomas,
Massachusetts General Hospital
Short Talk: TCF7L2 Deficiency Alters Mouse Metabolic and Islet
Cell Functions with Aging
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9:20 - 9:40 AM
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Coffee Break
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Foyer
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11:00 AM -
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On Own for Lunch and Recreation
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11:00 AM - 1:00 PM
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Poster Setup
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Foyer/Mountain View/Sea to Sky Ballroom A
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1:00 - 10:00 PM
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Poster Viewing
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Foyer/Mountain View/Sea to Sky Ballroom A
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4:30 - 5:00 PM
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Coffee Available
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Foyer
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5:00 - 7:15 PM
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Molecular Mechanisms in Insulin Secretion and Action (Joint)
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Sea to Sky Ballroom B,C
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*
Barbara B. Kahn,
Beth Israel Deaconess Medical Center
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C. Ronald Kahn,
Joslin Diabetes Center
Insulin Signaling and Insulin Resistance: The Ultimate Systems Biology Problem
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Per-Olof Berggren,
Karolinska Institutet
Systems Biology Approach to Study Beta Cell Function and Survival
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Morris J. Birnbaum,
University of Pennsylvania
The Role of Akt in the Regulation of Hepatic Metabolism by Insulin
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Weiping Han,
Singapore Bioimaging Consortium
Short Talk: Molecular Regulation of Calcium-Dependent Insulin Secretion
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Jennifer L. Estall,
Dana-Farber Cancer Institute - Harvard Medical School
Short Talk: PGC-1alpha Negatively Regulates Hepatic FGF21 Expression by Modulating the Heme/Rev-Erbalpha Axis
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7:15 - 8:15 PM
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Social Hour w/ Lite Bites
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Foyer/Mountain View/Sea to Sky Ballroom A
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7:30 - 10:00 PM
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Poster Session 2
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Foyer/Mountain View/Sea to Sky Ballroom A
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| Thursday, April 15 |
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7:00 - 8:00 AM
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Breakfast
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Sea to Sky Ballroom A, Lower Level
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7:00 - 11:00 AM
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Poster Setup
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Foyer/Mountain View/Sea to Sky Ballroom A
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8:00 - 11:15 AM
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Control of Insulin Secretory Machinery in Diabetes
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Sea to Sky Ballroom B
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*
Per-Olof Berggren,
Karolinska Institutet
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Patrik Rorsman,
Oxford Centre for Diabetes, Endocrinology and Metabolism
Calcium Channels and Insulin Exocytosis
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Michele Solimena,
Dresden University of Technology
Signaling from the Insulin Granule to the Nucleus
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Gerard Karsenty,
Columbia University Medical Center
Regulation of Glucose Homeostasis by Osteocalcin
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Herbert Y. Gaisano,
University of Toronto
Molecular Mechanism of Insulin Granule-Granule Fusion Contributing to Biphasic Insulin Secretion
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Ja-young Kim,
Columbia University Medical Center
Short Talk: Abnormal Regulation of Basal Insulin Secretion in Mice Homozygous
for a Constitutively Deacetylated FoxO1 Allele
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Hail Kim,
University of California, San Francisco
Short Talk: Serotonin Regulates Pancreatic beta-Cell Mass during Pregnancy
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9:50 - 10:10 AM
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Coffee Break
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Foyer
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11:00 AM - 5:00 PM
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Poster Viewing
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Foyer/Mountain View/Sea to Sky Ballroom A
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11:30 AM - 12:30 PM
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Lunch
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Foyer/Mountain View/Sea to Sky Ballroom A
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12:30 - 2:30 PM
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Poster Session 3
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Foyer/Mountain View/Sea to Sky Ballroom A
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4:30 - 5:00 PM
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Coffee Available
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Foyer
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5:00 - 7:15 PM
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Emerging Targets for Improving Insulin Action and Secretion (Joint)
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Sea to Sky Ballroom B,C
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*
C. Ronald Kahn,
Joslin Diabetes Center
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Richard D. DiMarchi,
Indiana University
Novel Glucagon-Like Chimera Peptides – Virtues of Combinatorial Pharmacology
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David E. Moller,
Eli Lilly and Company
Challenges and Opportunities for Diabetes Drug Discovery
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Johan Auwerx,
École Polytechnique Fédérale de Lausanne
Integrating Metabolic Control by NAD+ Sensors
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Tian Q. Sun,
Rigel Inc.
Short Talk: Small Molecule Adiponectin Mimetics Improve Hepatic Steatosis and Insulin Sensitivity in Diabetic Mouse Models
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Christine Esau,
Regulus Therapeutics
Short Talk: Inhibition of Let-7 with Anti-miR Oligonucleotides Improves Insulin Resistance in DIO Mice
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7:15 PM -
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On Own for Dinner
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| Friday, April 16 |
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7:00 - 8:00 AM
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Breakfast
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Sea to Sky Ballroom A, Lower Level
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8:00 - 11:15 AM
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Insulin Secretion and Action in Humans (Joint)
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Sea to Sky Ballroom B,C
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*
Michael P. Czech,
University of Massachusetts Medical School
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Andrew Hattersley,
Peninsula Medical School
Learning from Genetic Beta Cell Defects in Man
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Anna Moore,
Massachusetts General Hospital
Imaging Pancreatic Islets in vivo: Current Status
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Juleen R. Zierath,
Karolinska Institutet
Gene/Environment Influence on Skeletal Muscle Insulin Sensitivity in Type 2 Diabetic Patients
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Peter Arner,
Karolinska Institute
Dysfunction in Human Adipose Tissue and Insulin Resistance
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Michael Ristow,
University of Jena
Short Talk: Impaired Insulin Signaling Extends Life Span by Increasing Oxidative Stress
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Mary Armanios,
Johns Hopkins School of Medicine
Short Talk: Short Telomeres Lead to beta-cell Dysfunction and Impair Glucose Tolerance
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9:20 - 9:40 AM
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Coffee Break
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Foyer
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11:00 AM -
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On Own for Lunch and Recreation
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4:30 - 5:00 PM
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Coffee Available
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Foyer
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5:00 - 7:00 PM
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Beta Cell Stress in Diabetes
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Sea to Sky Ballroom B
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*
Marc A. Prentki,
CRCHUM/Université de Montreal
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Marc Y. Donath,
University Hospital Basel
Islet Inflammation in Type 2 Diabetes: Novel Mechanisms and Treatment
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Thomas Mandrup-Poulsen,
Hagedorn Research Institute
Cytokine Signaling in Inflammatory beta-Cell Destruction
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Rohit N. Kulkarni,
Joslin Diabetes Center
Insulin/IGF-I Signaling, Mitochondrial Function and Endoplasmic Stress in Pancreatic beta-Cells
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Raghavendra G. Mirmira,
Indiana University School of Medicine
Short Talk: The Unique Hypusine Modification of eIF5A Promotes Islet Inflammation and Dysfunction during the Development of Diabetes
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Foyer/Mountain View/Sea to Sky Ballroom A
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8:00 - 11:00 PM
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Entertainment
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Foyer/Mountain View/Sea to Sky Ballroom A
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| Saturday, April 17 |
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Departure
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