Keystone Symposia | Scientific Conferences on Biomedical and Life Science Topics

Synapses: Formation, Function and Misfunction (Z3)

Organizer(s): Matthew B. Dalva, Peter Scheiffele and Yishi Jin
April 11 - 15, 2010
Snowbird Resort · Snowbird, Utah
Abstract Deadline: December 10, 2009
Late Abstract Deadline: January 6, 2010
Scholarship Deadline: December 10, 2009
Early Registration Deadline: February 11, 2010

Supported by The Directors' Fund

Joint meeting: Toward Defining the Pathophysiology of Autistic Behavior (Z4)
NOTE: Registration for meeting allows attendance at joint meeting (pending space availability).

This meeting took place in the 2010 season.

For a complete list of the meetings for the upcoming/current season,
see our meeting list, or search for a meeting.

Summary of Meeting
During the last half-decade, a host of cellular mechanisms guiding synapse development have been identified. Exciting new links are being forged between our growing understanding of the basic processes and certain diseases. A major driving force in current research of synapses is new technologies. We propose to develop a meeting that would focus on these areas. Our meeting will bring together scientists working on the basic biological questions of how synapses form in model organisms, the development of new technology, and those with interests in understanding the links to human diseases.

Sunday, April 11
3:00 - 7:30 PM	Registration	Ballroom Lobby
6:30 - 7:30 PM	Refreshments	Ballroom Lobby
7:30 - 8:30 PM	Keynote Address (Joint)	Ballroom 2-3
	* Matthew B. Dalva, University of Pennsylvania

	Michael E. Greenberg, Harvard Medical School Signaling Networks that Control Synapse Development and Cognitive Function
Monday, April 12
7:00 - 8:00 AM	Breakfast	Golden Cliff/Eagles
8:00 - 11:15 AM	Circuit Formation	Ballroom 3
	* Yishi Jin, University of California, San Diego
	Anirvan Ghosh, University of California, San Diego On the Emergence of Synaptic Specificity in Developing Neural Circuits
	Kang Shen, Stanford University Intrinsic and Extrinsic Factors Pattern Synaptic Circuit Assembly in C. elegans
	Silvia Arber, Biozentrum, University of Basel & Friedrich Miescher Institute Mechanisms Controlling Synaptic Specificity in the Motor System

	Hitoshi Sakano, University of Tokyo Autonomous Topographic Map Formation by Olfactory Axons in Mouse
	Fatiha Boukhtouche, Biozentrum, University of Basel Short Talk: Trans-Synaptic BMP Signaling in the Ponto-Cerebellar Projection System
	Beatriz Rico, Instituto de Neurociencias de Alicante Short Talk: Control of Cortical GABAergic Circuitry Development by Nrg1/ErbB4 Signalling
9:20 - 9:40 AM	Coffee Break	Ballroom Lobby
11:15 AM -	On Own for Lunch and Recreation
11:15 AM - 1:00 PM	Poster Setup	Superior/Superior Lobby/Wasatch/Maybird
1:00 - 10:00 PM	Poster Viewing	Superior/Superior Lobby/Wasatch/Maybird
4:30 - 5:00 PM	Coffee Available	Ballroom Lobby
5:00 - 7:00 PM	Synaptic Adhesion and Signaling	Ballroom 3

	* Philip E. Washbourne, University of Oregon
	Matthew B. Dalva, University of Pennsylvania Postsynaptic Mechanisms Guiding Synapse Development

	Nils Brose, Max Planck Institute of Experimental Medicine Genetic Dissection of Neuroligin Function: From Synaptogenesis to Autism
	Lisa M. Boulanger, Princeton University Regulation of Synaptic Transmission and Synaptic Plasticity by MHC Class I
	Robby M. Weimer, Genentech Short Talk: Death Receptor 6 (DR6) Regulates Synapse Stability in vivo
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Superior/Superior Lobby/Wasatch/Maybird
7:30 - 10:00 PM	Poster Session 1	Superior/Superior Lobby/Wasatch/Maybird
Tuesday, April 13
7:00 - 8:00 AM	Breakfast	Golden Cliff/Eagles
8:00 - 11:15 AM	Transynaptic Mechanisms	Ballroom 3
	* Elva Diaz, University of California, Davis, School of Medicine
	Hisashi Umemori, University of Michigan Wiring the Functional Brain
	Thomas Biederer, Yale University Synaptic Adhesion Complexes Organize Synapse Development
	Michisuke Yuzaki, School of Medicine, Keio University Cbln1 and its Receptor: A Unique and Essential Bidirectional Synaptic Organizer Complex
	Vivian Budnik, University of Massachusetts Medical School Trans-Synaptic Transport of a Vesicular Wnt Signal
	Brian D. McCabe, Columbia University Short Talk: Retrograde Robo Signaling Coordinates Synaptic Maturation
	Matthew J. Kennedy, Duke University Short Talk: A Domain for Activity-Triggered Postsynaptic Exocytosis in Dendritic Spines
9:20 - 9:40 AM	Coffee Break	Ballroom Lobby
11:15 AM -	On Own for Lunch and Recreation
11:15 AM - 1:00 PM	Poster Setup	Superior/Superior Lobby/Wasatch/Maybird
1:00 - 10:00 PM	Poster Viewing	Superior/Superior Lobby/Wasatch/Maybird
4:30 - 5:00 PM	Coffee Available	Ballroom Lobby
5:00 - 7:00 PM	Glia Cells and Synapse Formation	Ballroom 3
	* Christopher W. Cowan, University of Texas-Southwestern Medical School
	Cagla Eroglu, Duke University Medical Center How do Astrocytes Induce Central Nervous System Synaptogenesis?
	Philip G. Haydon, Tufts University Glia: Listening and Talking to the Synapse
	Dwight E. Bergles, Johns Hopkins School of Medicine Synaptic Communication between Neurons and Glial Cells in the Mammalian Brain
	Suzanne Paradis, Brandeis University Short Talk: Elucidating the Function of Semaphorin 4D in GABAergic Synapse Formation
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Superior/Superior Lobby/Wasatch/Maybird
7:30 - 10:00 PM	Poster Session 2	Superior/Superior Lobby/Wasatch/Maybird
Wednesday, April 14
7:00 - 8:00 AM	Breakfast	Golden Cliff/Eagles
8:00 - 11:15 AM	Synaptic and Circuit Function in Neurodevelopmental Disorders (Joint)	Ballroom 3
	* Peter Scheiffele, Biozentrum, University Basel

	Jennifer Darnell, Rockefeller University HITS-CLIP Identifies Specific Neuronal mRNA Targets of Translational Repression by the Fragile X Mental Retardation Protein, FMRP
	Kimberly M. Huber, University of Texas Southwestern Medical Center Regulation of Synapse Number by Fragile X Mental Retardation Protein
	Ben D. Philpot, University of North Carolina at Chapel Hill Angelman Syndrome and Synaptic Plasticity

	Ann Marie Craig, University of British Columbia Molecular Assembly of Hippocampal Synapses
	Jeremy M. Veenstra-VanderWeele, Vanderbilt University Medical Center Short Talk: Hyperserotonemia, Enhanced Brain Serotonin Clearance, and Altered Behavior Accompany Knock-In of the Autism-Associated SERT Ala56 Variant
	Kristen Jennifer Brennand, The Salk Institute for Biological Studies Short Talk: Modeling Schizophrenia Using hiPS-Derived Neurons
9:20 - 9:40 AM	Coffee Break	Ballroom Lobby
11:15 AM -	On Own for Lunch and Recreation
4:30 - 5:00 PM	Coffee Available	Ballroom Lobby
5:00 - 7:00 PM	Technology	Ballroom 3

	* Erik Ullian, University of California, San Francisco
	Ed Callaway, The Salk Institute New Rabies-Based Tools for Studies of the Structure and Function of Neural Circuits

	Feng Zhang, Harvard Neural Engineering: Molecular and Optical Axis of Control


	Alexander Egner, Max Planck Institute for Biophysical Chemistry Nanoscopy with Focused Light
	Jun Ding, Harvard Medical School Short Talk: Deep Tissue Supraresolution Imaging of Neurons Using Stimulated-Emission Depletion 2-Photon Laser Scanning Microscopy
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Ballroom 1-2
8:00 - 11:00 PM	Entertainment	Ballroom 1-2
Thursday, April 15
	Departure

*Session Chair †Speaker invited, not yet responded.