Keystone Symposia | Scientific Conferences on Biomedical and Life Science Topics

Stem Cells (G4)

Organizer(s): Catherine M. Verfaillie and Austin G. Smith
March 27 - April 1, 2006
Whistler Conference Centre (meeting only) · Whistler, British Columbia
Abstract Deadline: November 28, 2005
Late Abstract Deadline: December 19, 2005
Scholarship Deadline: November 28, 2005
Early Registration Deadline: January 27, 2006

Supported by The Director's Fund

The University of Colorado School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The University of Colorado School of Medicine designates this educational activity for a maximum of 28-35 category 1 credits toward the AMA Physician's Recognition Award. Each physician should claim only those credits that he/she actually spent in the activity.

To receive CME credits, mark the box on the registration form, and pay the additional $50.00.

This meeting took place in the 2006 season.

Listed below are current meetings that are similar to this meeting in nature/content:

Stem Cells in Development, Tissue Homeostasis and Disease (B3)
January 30 - February 4, 2011

For a complete list of the meetings for the upcoming/current season,
see our meeting list, or search for a meeting.

Summary of Meeting
Elucidation of self-renewal and commitment pathways that determine stem cell fate are of great interest, both for fundamental biology and for clinical applications in regenerative medicine and cancer therapy. Many efforts are underway to determine cell intrinsic and microenvironmental signals that govern self-renewal and differentiation, and to identify genetic perturbations in these pathways that may result in tumourigenesis. By 2006, progress in unraveling cellular and molecular mechanisms can be expected to begin informing new strategies for clinical intervention. This conference will bring together stem cell biologists in the areas of self-renewal and tissue diversification, the stem cell niche, cancer stem cells and cell therapy, to discuss the biological and clinical significance of normal and malignant stem cell function.

Objectives
Upon completion of this conference, participants should be able to:

To explain current knowledge of stem cells, spanning from plant to man, and from tissue specific stem cells to pluripotent stem cells. This will include cell biological aspects, as well as signal transduction and transcriptional events that guide their self-renewal and differentiation.
To describe the notion that deregulation at the stem cell level is responsible for the development of malignancies.
To consider the biological and clinical significance of normal and malignant stem cell function.

Monday, March 27
3:00 - 7:30 PM	Registration	Sea to Sky Foyer
6:30 - 7:30 PM	Refreshments	Sea to Sky Foyer
7:30 - 8:30 PM	Keynote Address	Sea to Sky Ballroom A
	Anne McLaren, University of Cambridge Ethics and Science of Stem Cell Research
Tuesday, March 28
7:00 - 8:00 AM	Breakfast	Lower Level
8:00 - 11:00 AM	Stem Cell Niche	Sea to Sky Ballrm A
	* Ihor R. Lemischka, Mount Sinai School of Medicine
	Haifan Lin, Yale University Terra Incognita: Translational Regulation of Stem Cell Self-Renewal
	Shahragim Tajbakhsh, Institut Pasteur Myogenic Stem Cell Niche and Template DNA Segregation
	Robert Sablowski, John Innes Centre Plant Stem Cell Niches
	Shin-Ichi Nishikawa, RIKEN Center for Developmental Biology Comparison of Melanocyte and Mesenchymal Stem Cell Systems
	Samir Taoudi, Institute for Stem Cell Research, University of Edinburgh Short Talk: Anatomical Polarity of Definitive Hematopoietic Stem Cell Emergence and Expansion
9:20 - 9:40 AM	Coffee Break	Sea to Sky Ballrm B/C, Foyer
11:00 AM - 1:00 PM	Poster Setup	Sea to Sky Ballrm B/C, Foyer
1:00 - 10:00 PM	Poster Viewing	Sea to Sky Ballrm B/C, Foyer
4:30 - 5:00 PM	Coffee Available	Sea to Sky Ballrm B/C, Foyer
5:00 - 7:00 PM	Self-Renewal	Sea to Sky Ballrm A
	* Shin-Ichi Nishikawa, RIKEN Center for Developmental Biology
	Shinya Yamanaka, Center for iPS Cell Research and Application (CiRA), Kyoto University Pluripotency and Nuclear Reprogramming
	Guy Sauvageau, IRIC/Université de Montréal Bmi1 and Hoxb4 Regulate Proliferation and Fate of Hemopoietic Stem Cells
	Ihor R. Lemischka, Mount Sinai School of Medicine Stem Cell Circuitry
	Ryan E. Davey, University of Toronto Short Talk: Quantitative, Temporal and Spatial Analysis of Cell Signaling Reveals a Novel Autoregulatory Embryonic Stem Cell Niche
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Sea to Sky Ballrm B/C, Foyer
7:30 - 10:00 PM	Poster Session 1	Sea to Sky Ballrm B/C, Foyer
Wednesday, March 29
7:00 - 8:00 AM	Breakfast	Lower Level
8:00 - 11:00 AM	Tissue Diversification	Sea to Sky Ballrm A
	* Arturo Alvarez-Buylla, University of California, San Francisco

	Jason H. Pomerantz, Stanford University Short Talk: Chromatin Remodeling during Nuclear Reprogramming by Somatic Cell Fusion

	Gordon M. Keller, University Health Network, MaRS Centre Commitment of ES Cells to Mesoderm and Endoderm
	Jonathan M.W. Slack, University of Bath Transdifferentiation and Metaplasia in the Endoderm
	Yann Barrandon, École Polytechnique Fédérale de Lausanne Epidermis and Epithelia
	Sharon Gerecht-Nir, Short Talk: Mechanotransduction Signaling during Differentiation of Human Embryonic Stem Cells on Nanopatterned Surfaces
9:20 - 9:40 AM	Coffee Break	Sea to Sky Ballrm B/C, Foyer
11:00 AM - 1:00 PM	Poster Setup	Sea to Sky Ballrm B/C, Foyer
1:00 - 10:00 PM	Poster Viewing	Sea to Sky Ballrm B/C, Foyer
4:30 - 5:00 PM	Coffee Available	Sea to Sky Ballrm B/C, Foyer
5:00 - 7:00 PM	Cellular and Nuclear Reprogramming	Sea to Sky Ballrm A
	* Guy Sauvageau, IRIC/Université de Montréal
	Gerold Schubiger, University of Washington Transdetermination in Drosophila Imaginal Discs
	Markus Grompe, Oregon Health & Science University In vivo reduction divisions in cells reprogrammed by fusion
	Rudolf Jaenisch, Whitehead Institute for Biomedical Research Cloning and Nuclear Transfer
	Nobuaki Kikyo, University of Minnesota Short Talk: Chromatin Decondensation and Nuclear Reprogramming in Somatic Cell Nuclear Cloning
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Sea to Sky Ballrm B/C, Foyer
7:30 - 10:00 PM	Poster Session 2	Sea to Sky Ballrm B/C, Foyer
Thursday, March 30
7:00 - 8:00 AM	Breakfast	Lower Level
8:00 - 11:00 AM	Neural Differentiation	Sea to Sky Ballrm A
	* Olle Lindvall, University of Lund
	Austin G. Smith, University of Cambridge From Embryonic Stem (ES) Cells to Neural Stem (NS) Cells and Back Again
	Wieland B. Huttner, Max Planck Institute of Molecular Cell Biology and Genetics The Cell Biology of Neurogenesis

	Arturo Alvarez-Buylla, University of California, San Francisco Subventricular Zone Astrocytes Expressing PDGF Receptors Function as Adult Brain Progenitors
	Laurie A. Boyer, Massachusetts Institute of Technology Short Talk: Transcriptional Regulation of Pluripotency in Embryonic Stem Cells
9:20 - 9:40 AM	Coffee Break	Sea to Sky Ballrm B/C, Foyer
11:00 AM - 1:00 PM	Poster Setup	Sea to Sky Ballrm B/C, Foyer
1:00 - 10:00 PM	Poster Viewing	Sea to Sky Ballrm B/C, Foyer
4:30 - 5:00 PM	Coffee Available	Sea to Sky Ballrm B/C, Foyer
5:00 - 7:00 PM	Cancer Stem Cells	Sea to Sky Ballrm A
	* Irving L. Weissman, Stanford University
	Irving L. Weissman, Stanford University Normal and Neoplastic Hematopoiesis

	Michael F. Clarke, Stanford University Breast Cancer Stem Cells

	Peter Dirks, Hospital for Sick Children Charaterization of Human Brain Tumor Initiating Cells
	Malcolm R. Alison, Queen Mary University of London Short Talk: Colonic Stem Cells are Unable to Selectively Segregate their Genome at the Time of Mitosis: Any Replication Errors Could Persist in Stem Cells
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Sea to Sky Ballrm B/C, Foyer
7:30 - 10:00 PM	Poster Session 3	Sea to Sky Ballrm B/C, Foyer
Friday, March 31
7:00 - 8:00 AM	Breakfast	Lower Level
8:00 - 11:15 AM	Regeneration and Adult Multipotency	Sea to Sky Ballrm A
	* Austin G. Smith, University of Cambridge
	Elly M. Tanaka, Center for Regenerative Therapies, Dresden The Neural Progenitor Cells for Spinal Cord Regeneration
	Giulio Cossu, Stem Cell Research Institute Cell therapy of the Golden Retriever Muscular Dystrophy by systemic delivery of donor mesoangioblasts
	Freda D. Miller, Hospital for Sick Children, University of Toronto Skin-Derived Neural Crest Precursors (SKPs): What, Where and Why?
	Catherine M. Verfaillie, University of Minnesota Multipotent Adult Progenitor Cells

	Michelle B. Bowie, British Columbia Cancer Agency Identification of a Programmed Developmental Switch in Hematopoietic Stem Cell Properties
9:20 - 9:40 AM	Coffee Break	Sea to Sky Ballrm B/C, Foyer
11:00 AM - 12:00 PM	Poster Setup	Sea to Sky Ballrm B/C, Foyer
12:00 - 2:30 PM	Poster Session 4	Sea to Sky Ballrm B/C, Foyer
12:00 - 1:00 PM	Light Lunch	Lower Level
12:00 - 5:00 PM	Poster Viewing	Sea to Sky Ballrm B/C, Foyer
4:30 - 5:00 PM	Coffee Available	Sea to Sky Ballrm B/C, Foyer
5:00 - 7:00 PM	Therapeutic Prospects	Sea to Sky Ballrm A
	* Giulio Cossu, Stem Cell Research Institute
	Michele De Luca, University of Modena and Reggio Emilia and The Veneto Eye Bank Foundation Human Epithelial Stem Cells in Regenerative Medicine
	Olle Lindvall, University of Lund Neuronal Replacement for Brain Repair in Humans
	Ronald D. McKay, National Institutes of Health Stem Cell Renewal and Regeneration in the CNS
	Alexandra Aicher, University of Frankfurt Short Talk: The Wnt Antagonist Dickkopf-1 (Dkk-1) Mobilizes Endothelial Progenitor Cells
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Sea to Sky Ballrm B/C, Foyer
8:00 - 11:00 PM	Entertainment	Sea to Sky Ballrm B/C
Saturday, April 1
	Departure

*Session Chair †Speaker invited, not yet responded.