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Systems Biology: Integrating Biology, Technology and Computation (C6)

Organizer(s): Alan Aderem and Leroy E. Hood
March 5 - 10, 2006
Sagebrush Inn and Conference Center  ·  Taos, New Mexico
Abstract Deadline: November 3, 2005
Late Abstract Deadline: November 28, 2005
Scholarship Deadline: November 3, 2005
Early Registration Deadline: January 5, 2006


Supported by The Director's Fund



This meeting took place in the 2006 season.

For a complete list of the meetings for the upcoming/current season,
see our meeting list, or search for a meeting.
Summary of Meeting
Biological inquiry has undergone a number of profound changes. Early studies emphasized complex systems, whereas recent studies have shied away from complexity, instead focusing on detailed knowledge of circumscribed physiologic, cellular and molecular entities. The sequencing of the human genome, in concert with emerging genomic and proteomic technologies, permits the definition of a complete and dynamic parts list of all biological systems. When harnessed with powerful new computational approaches it will be possible to obtain a comprehensive molecular description of complex biological processes. This meeting will focus on the symbiotic interplay between biology, technology, and computation that lies at the heart of systems biology.

Sunday, March 5
3:00 - 7:30 PM Registration Chamisa Lobby
6:30 - 7:30 PM Refreshments Chamisa Lobby
7:30 - 8:30 PM Keynote Address Chamisa Ballroom 1
Eric H. Davidson, California Institute of Technology
Systems Approaches to Sea Urchin Development
Monday, March 6
7:00 - 8:00 AM Breakfast Los Vaqueros
8:00 - 11:00 AM Systems Biology of Prokaryotes Chamisa Ballroom 1
Elizabeth A. Winzeler, The Scripps Research Institute-GNF
Applied Systems Biology: Using Genomics to Find New Therapies for Malaria
* Adam P. Arkin, University of California Berkeley
Adversity, Diversity and Design: Dynamics of Cellular Networks From Bacterial Signaling to Desigh of a Tumor Killing Bactirium
Nitin S. Baliga, Institute for Systems Biology
From Genome to Network in Four Years: Formulating a Productive Model for Whole Cell Environmental Responses
Björn Titz, Forschungszentrum Karlsruhe
Short Talk: The Protein Interaction Map of T. pallidum – A Minimal Prokaryotic Genome
9:20 - 9:40 AM Coffee Break Chamisa Lobby
11:00 AM - 1:00 PM Poster Setup Chamisa Ballroom 2
1:00 - 10:00 PM Poster Viewing Chamisa Ballroom 2
4:30 - 5:00 PM Coffee Available Chamisa Lobby
5:00 - 7:00 PM The Impact of Genomics and Proteomics on Dissecting Complex Biological Processes Chamisa Ballroom 1
* Rudolf H. Aebersold, Institute of Molecular Systems Biology, ETH Zurich
Quantitative Proteomics and Systems Biology
Brian T. Chait, Rockefeller University
Analyzing Complex Biological Machines
Ronald W. Davis, Stanford University
New Genomic Technologies for Systems Biology
Aditya P. Singh, University of New Mexico
Short Talk: A Detailed Kinetic Model for a Bistable Genetic Network
7:00 - 8:00 PM Social Hour w/ Lite Bites Chamisa Ballroom 2
7:30 - 10:00 PM Poster Session 1 Chamisa Ballroom 2
Tuesday, March 7
7:00 - 8:00 AM Breakfast Los Vaqueros
8:00 - 11:00 AM Systems Biology of Eukaryotes Chamisa Ballroom 1
John D. Aitchison, Institute for Systems Biology
Systems Biology Applied to Organelle Biogenesis
Michael S. Levine, University of California, Berkeley
A Regulatory Network Controlling Drosophila Gastrulation
* Richard A. Young, Whitehead Institute for Biomedical Research
Transcriptional Regulating Circutry
Alan Aderem, Institute for Systems Biology
A Systems Approach to Dissecting Immunity
Leor S. Weinberger, Princeton University
Short Talk: A Tale of Two Circuits: How HIV and Herpes Use Simple Feedback Motifs to Control Lifecycle Choices
9:20 - 9:40 AM Coffee Break Chamisa Lobby
11:00 AM - 1:00 PM Poster Setup Chamisa Ballroom 2
1:00 - 10:00 PM Poster Viewing Chamisa Ballroom 2
4:30 - 5:00 PM Coffee Available Chamisa Lobby
5:00 - 7:00 PM Dynamic Network Analysis Chamisa Ballroom 1
Hamid Bolouri, Institute for Systems Biology
Three Computational Aids for Reconstruction of Genetic Regulatory Networks in Developing Embryos
* Peer Bork, European Molecular Biology Laboratory
Towards Dynamic Protein Networks
Trey Ideker, University of California, San Diego
Protein Network Comparative Genomics
Insuk Lee, University of Texas, Austin
Short Talk: A Probabilistic Functional Gene Network of Yeast: A Conceptual Framework for Systems Biology
7:00 - 8:00 PM Social Hour w/ Lite Bites Chamisa Ballroom 2
7:30 - 10:00 PM Poster Session 2 Chamisa Ballroom 2
Wednesday, March 8
7:00 - 8:00 AM Breakfast Los Vaqueros
8:00 - 11:00 AM Emerging Technologies Chamisa Ballroom 1
* Jim R. Heath, California Institute of Technology
Nanosystems Biology and in vitro and in vivo Diagnostics of Cancer
Steve Quake, Stanford University
Biological Large Scale Integration
George M. Whitesides, Harvard University
New Frontiers in Microfluidics
Rich Bonneau, NYU Center for Comparative Functional Genomics
The Human Proteome Folding Project: Automated Function Annotation from Rosetta Structure Prediction for >90 Representative Genomes
Gal F. Almogy, Stanford University
Short Talk: A Novel Analog-Like Artificial Regulation System
9:20 - 9:40 AM Coffee Break Chamisa Lobby
11:00 AM - 1:00 PM Poster Setup Chamisa Ballroom 2
1:00 - 10:00 PM Poster Viewing Chamisa Ballroom 2
4:30 - 5:00 PM Coffee Available Chamisa Lobby
5:00 - 7:00 PM Using Comparative Genomics to Decipher Biological Information Chamisa Ballroom 1
* Eric D. Green, National Institutes of Health
Deducing Mammalian Genome Function by Multi-Species Comparative Sequencing
Edward M. Rubin, Lawrence Berkeley National Laboratory
Comparative Genomic Based Analysis
Svante Pääbo, Max Planck Institute for Evolutionary Anthropology
Comparitive Primate Genomics
Marc Vidal, Dana-Farber Cancer Institute
7:00 - 8:00 PM Social Hour w/ Lite Bites Chamisa Ballroom 2
7:30 - 10:00 PM Poster Session 3 Chamisa Ballroom 2
Thursday, March 9
7:00 - 8:00 AM Breakfast Los Vaqueros
8:00 - 11:00 AM New Approaches and Opportunities
Michael Tyers, University of Edinburgh
Systematic Analysis and Perturbation of Biological Networks
* Bernhard O. Palsson, University of California, San Diego
Genome-Scale Analysis of E. coli Adaptation to New Growth Environments, Including Re-Sequencing, Location Analysis and Expression Profiling
Terry Gaasterland, University of California, San Diego
RNA Control Networks: microRNAs and their Targets in Plants and Plankton
Michael E. Phelps, University of California, Los Angeles
Molecular Imaging Assays of Protein Targets with PET: From Mice to Patients
Vincent Rouilly, Imperial College London
Short Talk: Integrated Laboratory Information System for in Silico Experiment Validation
9:20 - 9:40 AM Coffee Break Chamisa Lobby
4:30 - 5:00 PM Coffee Available Chamisa Lobby
5:00 - 7:00 PM The Promise of Systems Biology for Medicine Chamisa Ballroom 1
Zhanzhi Hu, University of Texas at Austin
Short Talk: Reconstruction of the Functional Network of Transcriptional Regulation in Saccharomyces cerevisiae
Stuart K. Kim, Stanford University Medical Center
Systems Biology of Aging
Leroy E. Hood, Institute for Systems Biology
Systems Medicine and a Systems Approach to Disease
7:00 - 8:00 PM Social Hour w/ Lite Bites Chamisa Ballroom 2
8:00 - 11:00 PM Entertainment Chamisa Ballroom 2
Friday, March 10
Departure
*Session Chair   †Speaker invited, not yet responded.



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