Keystone Symposia | Scientific Conferences on Biomedical and Life Science Topics

Reproduction: Advances and Challenges (C1)

Organizer(s): Susan J. Fisher, Sudhansu K. Dey and R. Michael Roberts
February 20 - 25, 2007
Eldorado Hotel & Spa · Santa Fe, New Mexico
Abstract Deadline: October 20, 2006
Late Abstract Deadline: November 20, 2006
Scholarship Deadline: October 20, 2006
Early Registration Deadline: December 20, 2006

Sponsored by EMD Serono, Inc.

The University of Colorado School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The University of Colorado School of Medicine designates this educational activity for a maximum of 28-35 category 1 credits toward the AMA Physician's Recognition Award. Each physician should claim only those credits that he/she actually spent in the activity.

To receive CME credits, mark the box on the registration form, and pay the additional $50.00.

This meeting took place in the 2007 season.

For a complete list of the meetings for the upcoming/current season,
see our meeting list, or search for a meeting.

Summary of Meeting
Reproduction is a complicated process designed to diversify and strengthen the genetic complement of the offspring. Accordingly, the field of reproduction, which has spawned many important research areas such as stem cell biology, spans a wide spectrum of topics that greatly impact human health. This meeting will bring together leaders in the field of mammalian reproduction. The sessions will focus on critical molecular determinants of reproductive success in the context of hormonal, immunologic and genetic factors. Areas that will be covered include ovarian and testicular development and function together with gametogenesis. Additionally, placental and uterine biology will be highlighted as well as the mechanisms, including the actions of steroid hormones, coordinating the dialogue between embryonic and maternal cells, which culminates in implantation. The meeting will conclude by summarizing important new developments in the areas of immunology and epigenetic regulation of gene expression as related to reproductive processes.

Objectives
Upon completion of this conference, participants should be able to:

To discuss the mechanisms that control ovarian function and testicular development, including oocyte and sperm biology.
To understand uterine receptivity, placental development and the processes, including steroid actions, that lead to implantation.
To describe the interplay among the immune system, epigenetic phenonomena, endocrinology, and reproduction.
To consider possibilities for translational research between animal models and human disease research focused on reproduction.

Tuesday, February 20
3:00 - 7:30 PM	Registration	North Concourse
6:30 - 7:30 PM	Refreshments	Sunset Room
7:30 - 8:30 PM	Keynote Address	Anasazi Ballroom
	* Susan J. Fisher, University of California, San Francisco
	Bert W. O'Malley, Baylor College of Medicine The Role of Coactivators in Steroid Receptor Actions: Mechanisms, Physiology and Disease
Wednesday, February 21
7:00 - 8:00 AM	Breakfast	Eldorado Court
8:00 - 11:00 AM	Female Reproduction/Ovarian Biology	Anasazi Ballroom
	* Bert W. O'Malley, Baylor College of Medicine
	JoAnne S. Richards, Baylor College of Medicine Molecular Road Map to Ovulation
	Marco Conti, University of California, San Francisco Endocrine-Paracrine Regulation in the Ovary

	Hans R. Schöler, Max Planck Institute for Molecular Biomedicine From Oocytes to Stem Cells - from Stem Cells to Oocytes
	Janet E. Hall, Massachusetts General Hospital Reproductive Aging in Women
	Lanping Hao, Temple University School of Medicine Short Talk: Analysis of Differential Methylation at the ovum mutant (Om) Locus
9:20 - 9:40 AM	Coffee Break	Zia Concourse
11:00 AM - 1:00 PM	Poster Setup	Sunset Room
1:00 - 10:00 PM	Poster Viewing	Sunset Room
4:30 - 5:00 PM	Coffee Available	Zia Concourse
5:00 - 7:00 PM	Male Reproduction/Testicular Biology	Anasazi Ballroom
	* JoAnne S. Richards, Baylor College of Medicine
	Blanche Capel, Duke University Medical Center Signaling Pathways Regulating Sex Determination
	Michael D. Griswold, Washington State University The Role of the Sertoli Cell in the Differentiation of Spermatogonia and the Onset of the Cycle of the Seminiferous Epithelium
	Martin M. Matzuk, Baylor College of Medicine Genetic Dissection of Mammalian Fertility Pathways
	Louise N. Reynard, MRC National Institute of Medical Research Short Talk: Analysis of the Role of X/Y Homologous Gene Family Xmr/Sly in Spermiogenesis
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Eldorado Court/Sunset Room
7:30 - 10:00 PM	Poster Session 1	Sunset Room
Thursday, February 22
7:00 - 8:00 AM	Breakfast	Eldorado Court
8:00 - 11:00 AM	Egg and Sperm Biology	Anasazi Ballroom
	* Sudhansu K. Dey, Cincinnati Children's Hospital Medical Center
	John J. Eppig, The Jackson Laboratory Oocyte Control of Granulosa Cell Development and Function
	Richard M. Schultz, University of Pennsylvania Gene Expression During Oocyte and Preimplantation Embryo Development in Mouse
	Barbara B. Knowles, ASTAR Genome Constancy and Plasticity During the Cocyte-to-Embryo Transition*
	Masaru Okabe, Osaka University Factors Involved in Sperm-Egg Interactions Examined by Gene-Manipulated Animals
9:20 - 9:40 AM	Coffee Break	Zia Concourse
11:00 AM - 1:00 PM	Poster Setup	Sunset Room
1:00 - 10:00 PM	Poster Viewing	Sunset Room
4:30 - 5:00 PM	Coffee Available	Zia Concourse
5:00 - 7:00 PM	Uterine Biology and Implantation	Anasazi Ballroom
	* R. Michael Roberts, University of Missouri
	Jan-Åke Gustafsson, Karolinska Institute Role of Estrogen Receptor Beta in Reproduction
	Daniel D. Carson, University of Delaware MUC1, A Key Cell Surface Component of Uterine Epithelia
	Fuller W. Bazer, Texas A&M University Uterine Factors Regulating Conceptus Development in Domestic Animals
	Haibin Wang, Chinese Academy of Sciences Short Talk: Endocannabinoid Signaling Directs Periimplantation Events
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Eldorado Court/Sunset Room
7:30 - 10:00 PM	Poster Session 2	Sunset Room
Friday, February 23
7:00 - 8:00 AM	Breakfast	Eldorado Court
8:00 - 11:00 AM	Placental Biology	Anasazi Ballroom
	* Susan J. Fisher, University of California, San Francisco
	Davor Solter, Institute of Medical Biology A Recurring Dilemma: Preformation Versus Epigenesis in Patterning Early Mouse Embryos

	Jerold J. Chun, The Scripps Research Institute Lysophospholipid Signaling in Both Implantation and Male Fertility

	Debra S. Goldman-Wohl, Hadassah Medical Organization When Killers become Builders: The Role of NK Cells in Human Placental Development
	Emin Maltepe, University of California, San Francisco Oxygen, HIF and the Regulation of Stem Cell Fate in the Placenta
9:20 - 9:40 AM	Coffee Break	Zia Concourse
4:30 - 5:00 PM	Coffee Available	Zia Concourse
5:00 - 7:00 PM	Steroid Hormone Actions	Anasazi Ballroom
	* Martin M. Matzuk, Baylor College of Medicine
	David F. Smith, Mayo Clinic-Scottsdale Regulation of Steroid Receptor Activity by the Hsp90 Co-Chaperone FKBP52
	Eric R. Prossnitz, University of New Mexico Transmembrane Estrogen Receptors in Reproductive Tissues
	Linda C. Giudice, University of California, San Francisco Uterine Receptivity and Early Implantation in Humans
	Yvette M. Huet-Hudson, University of North Carolina Short Talk: Estrogen Regulation of Endotoxic Shock Susceptibility
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Eldorado Court/Sunset Room
8:00 - 10:00 PM	Workshop: Trophoblast Specification and Differentiation	Anasazi Ballroom
	Chi-Wei Lu, Children's Hospital Boston Trophectoderm Lineage Establishment by Ras-MapKinase Signaling
	Claire M. Kershaw-Young, University of Sydney Factors Involved in the Derivation of Cytotrophoblast Cells from Human Embryonic Stem Cells
	Jennifer Dackor, University of North Carolina, Chapel Hill Modifiers in DBA/2J and C3Heb/FeJ Mouse Strains Cause Abnormal Embryo Spacing and Placental Fusion
Saturday, February 24
7:00 - 8:00 AM	Breakfast	Eldorado Court
8:00 - 11:00 AM	Immunology in Reproduction	Anasazi Ballroom

	* Davor Solter, Institute of Medical Biology
	Jack L. Strominger, Harvard University A Role for Galectin-1 Secreted by Decidual NK Cells in Fetal-Maternal Immune Tolerance
	Ashley Moffett, University of Cambridge Natural Killer Cells and Reproductive Success

	Susan J. Fisher, University of California, San Francisco Human Placentation: Borrowing From Lymphatics and Leukocytes
	Adrian Erlebacher, New York University School of Medicine Short Talk: Molecular and Anatomical Pathways that Mediate the Maternal T Cell Response Towards the Allogeneic Fetus
9:20 - 9:40 AM	Coffee Break	Zia Concourse
4:30 - 5:00 PM	Coffee Available	Zia Concourse
5:00 - 7:15 PM	Epigenetics in Reproduction: X-Inactivation, Imprinting, Nutrition	Anasazi Ballroom

	* David W. Threadgill, University of North Carolina at Chapel Hill
	Neil Brockdorff, Medical Research Council, Clinical Sciences Centre Reactivation of the X Chromosome in Early Mouse Development.
	R. Michael Roberts, University of Missouri Maternal Diet and Reproductive Outcome
	Randy L. Jirtle, Duke University Medical Center Epigenetics, Imprinting and the Fetal Origin of Disease
	Tilo Kunath, University of Edinburgh Extraembryonic Stem Cells
7:15 - 8:15 PM	Social Hour w/ Lite Bites	Eldorado Court/Sunset Room
8:00 - 11:00 PM	Entertainment	Eldorado Court/Sunset Room
Sunday, February 25
	Departure

*Session Chair †Speaker invited, not yet responded.