| Sunday, January 13 |
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3:00 - 7:30 PM
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Registration
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Shavano Peak Foyer
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6:30 - 7:30 PM
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Refreshments
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Shavano Peak Foyer
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7:30 - 9:30 PM
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Keynote Session (Joint)
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Crestone/Red Cloud/Shavano
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Timothy A. Springer,
Immune Disease Institute
Transendothelial Migration and Bidirectional Signal Transmission in Integrins
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Amanda E.I. Proudfoot Fichard,
Merck Serono Geneva Research Centre
Targeting the Chemokine System: From Technology to Evolution
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| Monday, January 14 |
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7:00 - 8:00 AM
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Breakfast
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Grays Peak 1-3
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8:00 - 11:15 AM
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Cell Biology of Migration (Joint)
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Crestone/Red Cloud/Shavano
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Emilio Hirsch,
University of Torino
PI3K gamma in Lymphocyte Trafficking
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Peter Friedl,
NCMLS, Radboud University Nijmegen Medical Centre
Cell Migration through Extracellular Matrix
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Stephen J. Weiss,
University of Michigan
MMPs and Cell Migration: Just How Similar are Tumor Cells and Leukocytes?
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Dimitris Kioussis,
National Institute for Medical Research
Imaging of the Lymphoid System and Associated Organs
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Ashok Kumar,
Mayo Clinic College of Medicine
Short Talk: CXCR4 Signals in T lymphocytes by Trafficking into MTOC-Associated Signaling Endosome Complex (MSEC)
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Lawrence Shiow,
University of California, San Francisco
Short Talk: Characterization of ptcd – a Spontaneous Thymic Egress Mutant
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9:20 - 9:40 AM
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Coffee Break
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Shavano Peak Foyer
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11:15 AM - 1:00 PM
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Poster Setup
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Grays Peak 1-3
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1:00 - 10:00 PM
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Poster Viewing
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Grays Peak 1-3
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4:30 - 5:00 PM
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Coffee Available
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Shavano Peak Foyer
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5:00 - 7:00 PM
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Chemokines in Lymphoid Tissue Homeostasis
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Shavano/Torreys
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Reinhold Förster,
Hannover Medical School
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Tsvee Lapidot,
Weizmann Institute of Science
Regulation of Stem Cell Trafficking, Retention and Development
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Sergio A. Lira,
Mount Sinai School of Medicine
Construction of Extranodal Lymphoid Tissue in Pathology
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Yousuke Takahama,
University of Tokushima
The Chemokine System in the Construction and Function of the Thymus
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Scott N. Mueller,
University of Melbourne
Short Talk: Regulation of Homeostatic Chemokine Expression and Cell Trafficking during Immune Responses
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Grays Peak 1-3
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7:30 - 10:00 PM
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Poster Session 1
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Grays Peak 1-3
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| Tuesday, January 15 |
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7:00 - 8:00 AM
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Breakfast
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Grays Peak 1-3
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8:00 - 11:15 AM
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In Situ Visualization of Lymphocyte Migration and Activation (Joint)
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Crestone/Red Cloud/Shavano
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Michael Sixt,
Max Planck Institute of Biochemistry
The Role of Integrins in Leukocyte Migration and Motility
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Michael L. Dustin,
New York University School of Medicine
Natural Killer Patrolling of Liver Sinusoids
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Ronald N. Germain,
NIAID, National Institutes of Health
Dynamic Intravital Visualization of Immune Cell Activity Using 2-Photon Microscopy
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Charles P. Lin,
Harvard Medical School, Massachusetts General Hospital
In vivo Flow Cytometry
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Steffen Jung,
Weizmann Institute of Science
Short Talk: Perivascular Bone Marrow Dendritic cell clusters provide critical B cell survival signals
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Britta Engelhardt,
Theodor Kocher Institute/Universitat Bern
Short Talk: In vivo imaging of natalizumab reduced T cell interaction with the blood-brain barrier
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9:20 - 9:40 AM
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Coffee Break
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Shavano Peak Foyer
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11:15 AM - 1:00 PM
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Poster Setup
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Grays Peak 1-3
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1:00 - 10:00 PM
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Poster Viewing
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Grays Peak 1-3
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2:30 - 4:30 PM
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Workshop 1: Chemokine Immunobiology and Signaling
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Shavano/Torreys
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Ann Richmond,
Vanderbilt University School of Medicine
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Jo Van Damme,
University of Leuven
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Konstanitina Alexandropoulos,
Immunology Institute, Mt. Sinai School of Medicine
A Signaling Complex Comprised of the Adapter Proteins Chat-H and CasL Regulates Activated but not Homeostatic T Cell Migration
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Songhai Chen,
Vanderbilt University
RACK1 Regulates Directional Cell Migration by Acting on G Protein beta gamma Subunits at the Interface with its Effectors PLCbeta and PI3Kgamma
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Richard A. Colvin,
Massachusetts General Hospital
CXCR3 Requires a Terminal PDZ-Binding Domain and Functionally Interacts with a PDZ-Domain containing Protein
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Giljun Park,
University of Tennessee at Knoxville
An N-terminal Single Point Mutation in CXCR2 Induces Constitutive Activity and Results in Cellular Transformation of NIH 3T3 Cells
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Daniel Campbell,
Benaroya Research Institute
Transcriptional Control of Regulatory T Cell Migration in vivo
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Ji-Liang Gao,
National Institutes of Health
Defective Cognitive Function In Mice Lacking of CX3CR1
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Aiko Shirakawa,
Kinki University School of Medicine
Induction of CCR10 by 1,25-Dihydroxyvitamin D3 in Terminally Differentiating Human B Cells
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Antje Margret Wengner,
Imperial College London
The Co-Ordinated Action of G-CSF and ELR+CXC Chemokines in Neutrophil Mobilisation during Acute Inflammation
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4:30 - 5:00 PM
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Coffee Available
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Shavano Peak Foyer
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5:00 - 7:00 PM
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The Chemokine System in Adaptive Immunity
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Shavano/Torreys
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*
Bernhard Moser,
Cardiff University School of Medicine
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Joshua M. Farber,
NIAID, National Institutes of Health
Chemokine Receptors on Th17 Cells and Other CD4+ Effector/Memory T Cell Subsets in Humans
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Gwendalyn J. Randolph,
Mount Sinai School of Medicine
The Unexpected Passage Of DC To Lymph Node Through Perinodal Adipose Tissue
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Karen E. Hedin,
Mayo Clinic
New Paradigms for Understanding How Chemokines Regulate Immunity: CXCR4 Signaling via the TCR
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James J. Campbell,
Brigham and Women's Hospital
Short Talk: Specificity And Dissemination Of Thropic Memory T Cells
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Grays Peak 1-3
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7:30 - 10:00 PM
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Poster Session 2
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Grays Peak 1-3
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| Wednesday, January 16 |
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7:00 - 8:00 AM
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Breakfast
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Grays Peak 1-3
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8:00 - 11:15 AM
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Tuning Chemokines in Inflammation
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Shavano/Torreys
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Robert J. Nibbs,
University of Glasgow
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Massimo Locati,
Istituto Clinico Humanitas IRCCS
Role of the Chemokine Decoy Receptor D6 in Balancing Inflammation, Immune Activation and Antimicrobial Resistance
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Antonio Alcami,
Centro de Biologia Molecular Severo Ochoa
Immune Modulation by Chemokine Binding Proteins from Herpesviruses
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John H. Kehrl,
NIAID, National Institutes of Health
Heterodimeric G Proteins In Chemokine Receptor Signalling and Lymphocyte Trafficking
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Marc E. Rothenberg,
Cincinnati Children's Hospital Medical Center
Chemokines in Eosinophils and Type II Inflammation
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Paul Proost,
Rega Institute, K.U.Leuven
Short Talk: CD13/Aminopeptidase N-Processed I-TAC/CXCL11 has Reduced CXCR3 and CXCR7 Binding and Signaling Properties that Result in Impaired Lymphocyte Chemotaxis and Reduced Inhibition of Endothelial Cell Migration
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Yi Le,
Naval Medical Research Center
Short Talk: Developmental Regulation of CXCR4-FAK Signaling by SOCS3 during B Lymphopoiesis
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9:20 - 9:40 AM
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Coffee Break
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Shavano Peak Foyer
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11:15 AM - 1:00 PM
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Poster Setup
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Grays Peak 1-3
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1:00 - 10:00 PM
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Poster Viewing
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Grays Peak 1-3
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4:30 - 5:00 PM
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Coffee Available
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Shavano Peak Foyer
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5:00 - 7:15 PM
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Lipids and Novel Modulators of Leukocyte Traffic (Joint)
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Crestone/Red Cloud/Shavano
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Joost J. Oppenheim,
National Institutes of Health
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Christian Weber,
University Hospital Aachen
Chemokine-Like Functions of MIF in Leukocyte Recruitment
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Annalisa Del Prete,
University of Bari
The Role of Chemerin in the Recruitment of Plasmacytoid Dendritic Cells in Normal and Pathological Conditions
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Andrew M. Tager,
Massachusetts General Hospital
Grease On Fire: Lipid-Chemokine Cooperation On Leukocyte Trafficking
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Takashi Saito,
RIKEN Center for Allergy and Immunology
Short Talk: CRTAM regulates retention of T cells within lymph node and delivery to effecter tissues
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Masayuki Miyasaka,
Osaka University Graduate School of Medicine
Short Talk: The role of a cell-motility inducing protein, autotaxin, in high endothelial venules of lymph nodes and Peyer’s patches
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7:15 - 8:15 PM
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Social Hour w/ Lite Bites
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Grays Peak 1-3
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7:30 - 10:00 PM
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Poster Session 3
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Grays Peak 1-3
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| Thursday, January 17 |
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7:00 - 8:00 AM
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Breakfast
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Grays Peak 1-3
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8:00 - 11:15 AM
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The Chemokine System in Pathology and Clinics
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Shavano/Torreys
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Robert M. Strieter,
University of Virginia School of Medicine
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Richard M. Ransohoff,
Cleveland Clinic
CXCR2 Deficiency Promotes CNS Myelin Repair: Anti-Inflammatory Neurobiological Effects
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Nicholas W. Lukacs,
University of Michigan
Chemokine Receptors and Leukocyte Accumulation Influence Pulmonary Disease Pathology
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Luigi D. Notarangelo,
Children's Hospital, Boston
Chemokine-Guided Leukocyte Traffic: Lessons from Human Congenital Immunodeficiencies
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Frances R. Balkwill,
Queen Mary University of London, Barts and The London Medical School
Chemokines and their Receptors in Gynaecological Malignancies
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Martine J. Smit†,
Vrije Universiteit
Short Talk: Viral Chemokine Receptor US28 Acts as Potential Oncogene: A Key Role for COX-2 in US28-Induced Tumorigenesis
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Nikolaos G. Frangogiannis,
Baylor College of Medicine
Short Talk: CXCL10/IP-10 Induction Orchestrates Infarct Healing
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9:20 - 9:40 AM
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Coffee Break
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Shavano Peak Foyer
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2:30 - 4:30 PM
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Workshop 2: Chemokines in Pathology and Therapy
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Shavano/Torreys
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Nicholas W. Lukacs,
University of Michigan
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Ting Jia,
Memorial Sloan Kettering Cancer Center
Role of MCP-3 in Monocyte Recruitment and Innate Immune Defense during Intracellular Bacterial Infection
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Shiro Kanegasaki,
Effector Cell Institute, Inc.
ECI301, an Active Variant of MIP-1alpha, Consistently Induced the Abscopal Effect of Radiation
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Pawel Kalinski,
University of Pittsburgh
Dendritic Cells Regulate the Lymphoid/Memory versus Peripheral/ Effector Pathway of Differentiation of CD8+ T Cells
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Marion Leick,
University Hospital Freiburg
The Orphan Chemokine Receptor CRAM-A/B is an Atypical Receptor Expressed on B Cells in a Maturation Stage Dependent and CCL5 Modulated Manner
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Jean K. Lim,
National Institutes of Health
Chemokine Receptor CCR2 Directs Macrophage Recruitment to the CNS and Promotes Survival from West Nile Virus Infection in Mice
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Federica Marchesi,
Istituto Clinico Humanitas
The Neurotactin/Fractalkine Chemokine Receptor CX3CR1 Mediates Perineural Invasion and Malignant Behavior of Human Ductal Pancreatic Adenocarcinoma
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Benjamin D. Medoff,
DRAI, Massachusetts General Hospital
CD11b+ Dendritic Cells are the Critical Cellular Mediator of Th2 Cell Homing into the Lung in Allergic Airway Inflammation
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Marco Prinz,
University of Freiburg
Spatial and Temporal Expression of CCR2 Determines the Outcome of Autoimmunity in the Central Nervous System
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4:30 - 5:00 PM
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Coffee Available
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Shavano Peak Foyer
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5:00 - 7:15 PM
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Chemokines as Targets for Pharmacological Intervention
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Shavano/Torreys
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Kouji Matsushima,
University of Tokyo School of Medicine
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Thomas J. Schall,
ChemoCentryx, Inc.
Targeting CCR9: Rationale and Clinical Development
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Elna Van Der Ryst,
Pfizer Global Research and Development
Challenges in the Design and Development of Maraviroc, a Novel CCR5 Antagonist for the Treatment of CCR5-Tropic HIV-1 Infection
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John F. Dipersio,
Washington University
CXCR4 and Hemopoietic Precursor Mobilization in the Clinic
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R. William Hipkin,
Schering-Plough Research Institute
Short Talk: SCH 527123: a Potent, Orally-Active CXCR2 Antagonist
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7:15 - 8:15 PM
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Social Hour w/ Lite Bites
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Grays Peak 1-3
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8:00 - 11:00 PM
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Entertainment
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Grays Peak 1-3
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| Friday, January 18 |
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Departure
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