| Monday, April 7 |
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3:00 - 7:30 PM
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Registration
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1st Floor Foyer
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6:30 - 7:30 PM
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Refreshments
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1st Floor Foyer
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7:30 - 8:30 PM
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Keynote Address
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Anderson Room
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Peter Fraser,
Babraham Institute
Introduction
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Susan M. Gasser,
Friedrich Miescher Institute for Biomedical Research
INO80 Chromatin Remodeling Complex at Breaks, Forks and Promoters: A Multitude of Functions
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| Tuesday, April 8 |
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7:00 - 8:00 AM
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Breakfast
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Hoaglund/Erickson/ Carrol/Sinclair
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8:00 - 11:15 AM
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Post-Translational Modifications of Histones
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Anderson Room
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*
Asifa Akhtar,
European Molecular Biology Laboratory
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Yi Zhang,
University of North Carolina at Chapel Hill
Role of Histone Methylation in Germ Cell Development and Stem Cell Pluripotency
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Kristian Helin,
University of Copenhagen
Epigenetic Control and the Development of Cancer
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Zhibin Wang,
NHLBI, National Institutes of Health
Short Talk: Combinatorial Patterns of Histone Acetylations and Methylations in the Human Genome
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Craig L. Peterson,
University of Massachusetts Medical School
Histone Modifications and Chromatin Structure
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Laurie A. Boyer,
Massachusetts Institute of Technology
Short Talk: H2AZ is Enriched at Polycomb Group Protein Target Regions in ES Cells and is Required for Proper Execution of Developmental Programs
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9:20 - 9:40 AM
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Coffee Break
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Hoaglund/Erickson/ Carrol/Sinclair
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11:00 AM - 1:00 PM
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Poster Setup
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Hoaglund/Erickson/ Carrol/Sinclair
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11:00 AM -
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On Own for Lunch
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1:00 - 10:00 PM
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Poster Viewing
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Hoaglund/Erickson/ Carrol/Sinclair
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4:30 - 5:00 PM
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Coffee Available
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Hoaglund/Erickson/ Carrol/Sinclair
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5:00 - 7:00 PM
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Atomic Structures of Chromatin Protein Complexes
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Anderson Room
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Vidya Subramanian,
MIT
Histone Chaperones: Structure, Function, and Regulation
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Masami Horikoshi,
University of Tokyo
Short Talk: From Histone Modification to Nuclesome Disassembly
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Ji-Joon Song,
Massachusetts General Hospital, Harvard Medical School
Short Talk: Structural Basis of Histone H4 Recognition by p55
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*
Sepideh Khorasanizadeh,
University of Virginia Health System
Multiple Roles for Chromodomains in Epigenetic Regulation
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Natalie Nady,
University of Toronto, Ontario Cancer Institute
Short Talk: Reading the Histone Code by MBT Domains – Structural Insights into MEthyl Mark Recognition
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Hoaglund/Erickson/ Carrol/Sinclair
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7:30 - 10:00 PM
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Poster Session 1
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Hoaglund/Erickson/ Carrol/Sinclair
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| Wednesday, April 9 |
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7:00 - 8:00 AM
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Breakfast
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Hoaglund/Erickson/ Carrol/Sinclair
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8:00 - 11:15 AM
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Chromatin Dynamics
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Anderson Room
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*
Steven Henikoff,
Fred Hutchinson Cancer Research Center
Histone Replacement Dynamics
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Robert Martienssen,
Cold Spring Harbor Laboratory
Slicing, Spreading and Copying Heterochromatin with RNAi
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Sevinc Ercan,
University of North Carolina
Short Talk: Dynamic and Bimodal Binding of the C. elegans Dosage Compensation Complex
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Andrea Schäfer,
German Cancer Research Center
Short Talk: Molecular Mechanism of Active DNA Demethylation
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Jessica K. Tyler,
MD Anderson Cancer Center
Chaperoning Histones
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Jonathan Widom,
Northwestern University
The Genomic Code for Nucleosome Positioning
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Raul A. Urrutia,
Mayo Clinic Rochester
Subcodes within the Histone Code
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9:20 - 9:40 AM
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Coffee Break
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Hoaglund/Erickson/ Carrol/Sinclair
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11:15 AM - 1:00 PM
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Poster Setup
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Hoaglund/Erickson/ Carrol/Sinclair
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11:15 AM -
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On Own for Lunch
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1:00 - 10:00 PM
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Poster Viewing
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Hoaglund/Erickson/ Carrol/Sinclair
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4:30 - 5:00 PM
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Coffee Available
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Hoaglund/Erickson/ Carrol/Sinclair
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5:00 - 7:00 PM
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Stem Cell Chromatin Dynamics
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Anderson Room
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Wolf Reik,
Babraham Institute
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Maarten Van Lohuizen,
Netherlands Cancer Institute
Polycomb Repressors Controlling Stem Cell Fate: Implications for Cancer and Development
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Bradley E. Bernstein,
Massachusetts General Hospital, Harvard Medical School
Chromatin Landscapes of Pluripotent and Lineage-Committed Cells
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Neil Brockdorff,
Medical Research Council, Clinical Sciences Centre
Chromatin Regulation by H2A Ubiquitylation
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Alexander Meissner,
Harvard University, Broad Institute
Short Talk: Genome-scale DNA Methylation Maps of Pluripotent and Differentiated Cells
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Laurie A. Boyer,
Massachusetts Institute of Technology
Short Talk: H2AZ is Enriched at Polycomb Group Protein Target Regions in ES Cells and is Required for Proper Execution of Developmental Programs
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Hoaglund/Erickson/ Carrol/Sinclair
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7:30 - 10:00 PM
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Poster Session 2
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Hoaglund/Erickson/ Carrol/Sinclair
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| Thursday, April 10 |
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7:00 - 8:00 AM
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Breakfast
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Hoaglund/Erickson/ Carrol/Sinclair
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7:00 - 8:00 AM
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Poster Setup
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Hoaglund/Erickson/ Carrol/Sinclair
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8:00 - 11:15 AM
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Epigenetics and Chromatin Modification Mechanisms
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Anderson Room
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*
Craig L. Peterson,
University of Massachusetts Medical School
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Shiv I. S. Grewal,
NCI, National Institutes of Health
Epigenetic Genome Control by RNAi and Transposon-Derived Proteins
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Francis Stewart,
Technische Universitaet Dresden
The Histone Methyltransferase, Mll2, is only Essential in a Brief Window during Development and for the Germ Lineage
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Rebecca Ann Mosher,
Cambridge University
Short Talk: PolIVb Influences RNA-Directed DNA Methylation and Demethylation Independently of its Role in siRNA Biogenesis
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Jürg Müller,
European Molecular Biology Laboratory
Transcriptional Control by the Polycomb System
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Kai Ge,
NIDDK, National Institutes of Health
Isolation of Histone H3K4 Methyltransferase Complexes that Associate with a Histone H3K27 Demethylase
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Matthew J. Gamble,
Cornell University
Short Talk: The Histone Variant MacroH2A1 Occupies Large Chromatin Domains and Positively Regulates Genes on Autosomes
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9:20 - 9:40 AM
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Coffee Break
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Hoaglund/Erickson/ Carrol/Sinclair
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11:15 AM - 12:15 PM
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Lunch
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Hoaglund/Erickson/ Carrol/Sinclair
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12:00 - 2:30 PM
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Poster Session 3
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Hoaglund/Erickson/ Carrol/Sinclair
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2:30 - 4:30 PM
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Workshop: Chromatin as a Drug Target
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Anderson Room
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*
Janine Arts,
Ortho Biotech Oncology Research and Development (J&J)
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Scott A. Armstrong,
Harvard Medical School
H3K79 Methylation Abnormalities Define Murine and Human MLL-AF4 Leukemias
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Tuncay Baubec,
Gregor Mendel Institute of Molecular Plant Biology
Zebularine is a Potent Inhibitor of Plant DNA Methylation
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Donghang Cheng,
MD Anderson Cancer Center
Arginine Methyltransferases as Novel Theraputic Targets for Breast Cancer
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Vibhor Gupta,
Jawaharlal Nehru University
Profiling the Epigenetic and Transcriptional Effects of Histone Deacetylase Inhibitors
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Joan Oliva Vilana,
LA Biomed
Spontanous Formation of Tumors in Drug Primed DDC Mice: An Epigenetic Phenomena
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Pedro Vladimir Pena,
University of Colorado Health Sciences Center
Molecular Mechanism of Histone H3K4Me3 Recognition by Plant Homeodomain of ING1 and the Effects of Cancer Specific Mutations
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4:30 - 5:00 PM
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Coffee Available
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Hoaglund/Erickson/ Carrol/Sinclair
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5:00 - 7:00 PM
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Large Scale Epigenetic Control
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Anderson Room
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*
Anne Ferguson-Smith,
University of Cambridge
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Asifa Akhtar,
European Molecular Biology Laboratory
Dosage Compensation and Chromatin Regulation
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Edith Heard,
Curie Institute
Nuclear and Chromatin Dynamics during X-Chromosome Inactivation
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Wolf Reik,
Babraham Institute
Epigenetic Regulation of Lineage Commitment and Pluripotency in the Mammalian Embryo
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Mareike Puschendorf,
Friedrich Miescher Institute
Short Talk: PRC1 and Suv39h Specify Parental Asymmetry at Constitutive Heterochromatin in Early Mouse Embryos
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7:00 PM -
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On Own for Dinner
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| Friday, April 11 |
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7:00 - 8:00 AM
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Breakfast
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Hoaglund/Erickson/ Carrol/Sinclair
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8:00 - 11:00 AM
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Nuclear and Chromosome Dynamics
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Anderson Room
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Edith Heard,
Curie Institute
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Peter Fraser,
Babraham Institute
3D Transcription Networks
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Yijun Ruan,
Genome Institute of Singapore
A Whole Genome View of Long-Range Chromatin Interactions in Transcription Regulation
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Michael R. Hübner,
Cold Spring Harbor Laboratory
Short Talk: Dynamic Analysis and Induction of Polycomb Bodies at a Specific Genetic Locus
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Vicki L. Chandler,
Gordon and Betty Moore Foundation
Interchromosomal Transfer of Epigenetic Information
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Anton Krumm,
University of Washington Medical Center
Short Talk: Role of Cohesion in Interphase Chromatin
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9:20 - 9:40 AM
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Coffee Break
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Hoaglund/Erickson/ Carrol/Sinclair
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11:00 AM -
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On Own for Lunch
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4:30 - 5:00 PM
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Coffee Available
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Hoaglund/Erickson/ Carrol/Sinclair
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5:00 - 7:00 PM
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Epigenomics and Disease
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Anderson Room
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*
Peter Fraser,
Babraham Institute
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Robert J. Sims,
Constellation Pharmaceuticals
Mechanisms of Epigenetic Signaling
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Janine Arts,
Ortho Biotech Oncology Research and Development (J&J)
Chromatin as a Drug Target
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Anne Ferguson-Smith,
University of Cambridge
The Establishment and Maintenance of Genomic Methylation Imprints
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Nathan R. Rose,
University of Oxford
Short Talk: Structural and Mechanistic Studies on the JMJD2 Histone Demethylases
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Hoaglund/Erickson/ Carrol/Sinclair
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8:00 - 11:00 PM
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Entertainment
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Hoaglund/Erickson/ Carrol/ Sinclair
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| Saturday, April 12 |
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Departure
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