| Tuesday, January 6 |
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3:00 - 7:30 PM
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Registration
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Lower Atrium
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6:30 - 7:30 PM
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Refreshments
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Lower Atrium
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7:30 - 8:30 PM
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Keynote Lecture
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Gallatin
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Lee M. Ellis,
University of Texas MD Anderson Cancer Center
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Luisa Iruela-Arispe,
University of California, Los Angeles
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Peter F. Carmeliet,
University of Leuven
Angiogenesis in Cancer
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| Wednesday, January 7 |
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7:00 - 8:00 AM
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Breakfast
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Jefferson/Madison
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8:00 - 11:00 AM
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Current Clinical Status of Anti-Angiogenic Therapy for Cancer
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Gallatin
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*
Lee M. Ellis,
University of Texas MD Anderson Cancer Center
Anti-VEGF Therapy: Successes and Failures in the Clinic
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Axel Grothey,
Mayo Clinic College of Medicine
Clinical Toxicities of Anti-VEGF Therapy - Focus on Bevacizumab
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John V. Heymach,
University of Texas MD Anderson Cancer Center
Circulating Endothelial Precursors as Surrogate Markers of Activity of Anti-VEGF Therapy
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Emile E. Voest,
University Medical Center Utrecht
Short Talk: Kinetics of Endothelial (Progenitor) Cell Release from the Bone Marrow in Patients Receiving Chemotherapy Predicts Response and Survival
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Mark A. Rosen,
University of Pennsylvania
Non-Invasive Imaging of the Tumor Vascular Phenotype in Humans Undergoing Anti-Vascular and Anti-Angiogenic Therapies
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9:20 - 9:40 AM
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Coffee Break
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Lower Atrium
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11:00 AM - 5:00 PM
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On Own for Lunch
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11:00 AM - 1:00 PM
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Poster Setup
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Jefferson/Madison
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1:00 - 10:00 PM
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Poster Viewing
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Jefferson/Madison
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4:30 - 5:00 PM
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Coffee Available
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Lower Atrium
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5:00 - 7:00 PM
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Abnormalities of the Tumor Microvascular Network
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Gallatin
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*
Luisa Iruela-Arispe,
University of California, Los Angeles
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Laura E. Benjamin,
Beth Israel Deaconess Medical Center
Akt Signaling in the Tumor Microenvironment
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David A. Cheresh,
University of California, San Diego
A Role for VEGF as a Negative Regulator of Pericyte Function and Vessel Maturation
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Ombretta Salvucci,
National Cancer Institute, National Institutes of Health
Short Talk: Requirement for EphrinB Activation in Mural Cells Association with Endothelial Cells during New Vessel Formation
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Robert S. Kerbel,
Sunnybrook Health Sciences Centre
Rapid Systemic Induction of Proangiogenic/Vasculogenic Factors by Chemotherapy or Antiangiogenic Drugs: Implications for Tumor Progression and Response to Therapy
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Jefferson/Madison
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7:30 - 10:00 PM
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Poster Session 1
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Jefferson/Madison
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| Thursday, January 8 |
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7:00 - 8:00 AM
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Breakfast
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Jefferson/Madison
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8:00 - 11:00 AM
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Tumor Angiogenesis, Inflammation and the Microenvironment
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Gallatin
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*
Laura E. Benjamin,
Beth Israel Deaconess Medical Center
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Luisa Iruela-Arispe,
University of California, Los Angeles
Intracrine VEGF Signaling and Tumor Growth
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Raymond N. DuBois,
University of Texas MD Anderson Cancer Center
Inflammatory Mediators and Tumor Progression
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Kristian Pietras,
Karolinska Institutet
Exploring New Strategies to Target the Pro-Angiogenic Tumor Stroma
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Calvin Kuo,
Stanford University
Short Talk: Angiogenic Phenotypes of the Egfl7 Locus are Attributable to the Embedded MicroRNA miR-126
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J. Silvio Gutkind,
National Institutes of Health
Semaphorin-Regulated Signaling Networks and Tumor-Induced Angiogenesis
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9:20 - 9:40 AM
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Coffee Break
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Lower Atrium
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11:00 AM - 5:00 PM
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On Own for Lunch
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11:00 AM - 1:00 PM
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Poster Setup
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Jefferson/Madison
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1:00 - 10:00 PM
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Poster Viewing
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Jefferson/Madison
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4:30 - 5:00 PM
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Coffee Available
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Lower Atrium
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5:00 - 7:00 PM
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Vascular Stem and Progenitor Cells
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Gallatin
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*
Robert S. Kerbel,
Sunnybrook Health Sciences Centre
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Richard J. Gilberston,
St Jude Children's Research Hospital
The Perivascular Niche for Tumor Stem Cells
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Robert Benezra,
Memorial Sloan-Kettering Cancer Center
Id Proteins and Vascular Mobilization
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Avner Adini,
Children's Hospital, Boston
Short Talk: Prominin-1/CD133, is More than a Marker of Premature Hematopoietic Cells
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M. Celeste Simon,
University of Pennsylvania
Hypoxia, HIF and Stem Cells
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Jefferson/Madison
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7:30 - 10:00 PM
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Poster Session 2
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Jefferson/Madison
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| Friday, January 9 |
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7:00 - 8:00 AM
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Breakfast
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Jefferson/Madison
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8:00 - 11:00 AM
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Tumor Lymphangiogenesis
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Gallatin
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*
Robert Benezra,
Memorial Sloan-Kettering Cancer Center
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Barbara H. Garmy-Susini,
University of California, San Diego
Central Requirement for Integrin Signaling in Lymphangiogenesis and Metastasis
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Michael J. Detmar,
ETH - Zürich
Molecular Control of Lymphangiogenesis
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Peter Friedl,
NCMLS, Radboud University Nijmegen Medical Centre
Collective Invasion and Radioresistance at the Tumor-Vessel Interface
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Yusuke Mizukami,
Asahikawa Medical College
Short Talk: Hedgehog Signaling Regulates Angiogenesis in Pancreatic Cancer
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Tuomas Tammela,
University of Helsinki
VEGFR-3 Pathway as a Target to Inhibit Angiogenesis, Lymphangiogenesis and Tumor Metastasis
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9:20 - 9:40 AM
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Coffee Break
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Lower Atrium
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11:00 AM - 5:00 PM
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On Own for Lunch
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11:00 AM - 1:00 PM
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Poster Setup
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Jefferson/Madison
|
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1:00 - 10:00 PM
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Poster Viewing
|
Jefferson/Madison
|
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4:30 - 5:00 PM
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Coffee Available
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Lower Atrium
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5:00 - 7:00 PM
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Imaging Angiogenesis: Histopathologic and Non-Invasive Imaging of Live Animals
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Gallatin
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Jan E. Schnitzer,
Proteogenomics Research Institute for Systems Medicine (PRISM)
Proteomic Imaging of Tumor Microenvironment and Angiogenesis in vivo for Enhancing Targeted Therapies
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Myunghwan Choi,
Korea Advanced Institute of Science and Technology
Short Talk: Dynamic Fluorescence Imaging for Multiparametric Measurement of Tumor Vasculature
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Lily Wu,
University of California, Los Angeles
Functional Molecular Imaging of Prostate Cancer Lymphatic Metastasis
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*
Donald M. McDonald,
University of California, San Francisco
Imaging of Cellular Actions of Angiogenesis Inhibitors
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Jefferson/Madison
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7:30 - 10:00 PM
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Poster Session 3
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Jefferson/Madison
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| Saturday, January 10 |
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7:00 - 8:00 AM
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Breakfast
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Jefferson/Madison
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8:00 - 11:00 AM
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Emerging Targets and Endothelial Cell Biology
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Gallatin
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*
Gregory D. Plowman,
Genentech
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Richard O. Hynes,
Massachusetts Institute of Technology
Cell-Matrix Interactions in Vascular Development
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Hellmut G. Augustin,
German Cancer Research Center (DKFZ) & University of Heidelberg
Angiopoietins and Tie-2
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Beverly A. Teicher,
Genzyme Corporation
Endosialin/CD248: The Evolution of a Target
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Napoleone Ferrara,
Genentech, Inc.
Myeloid Dependent Tumor Angiogenesis and Bv8
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9:20 - 9:40 AM
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Coffee Break
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Lower Atrium
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11:00 AM - 5:00 PM
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On Own for Lunch
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4:30 - 5:00 PM
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Coffee Available
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Lower Atrium
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5:00 - 7:00 PM
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Notch Signaling
|
Gallatin
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*
Jan K. Kitajewski,
Columbia University
Notch Signaling in Tumor Angiogenesis
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Nicholas W. Gale,
Regeneron Pharmaceuticals Inc.
Targeting Tumor Microvasculature via the VEGF and Delta/Notch Pathways
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Ji-Liang Li,
Weatherall Institute of Molecular Medicine, University of Oxford
Short Talk: DLL4 Enhances Tumour Growth and Mediates Tumour Resistance to Anti-VEGF Therapy in vivo
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Gregory D. Plowman,
Genentech
Contrasting Roles of VEGF and DLL4 in Vascular Biology
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7:00 - 8:00 PM
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Social Hour w/ Lite Bites
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Jefferson/Madison
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8:00 - 11:00 PM
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Entertainment
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Jefferson/Madison
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| Sunday, January 11 |
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Departure
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