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Frontiers in Reproductive Biology and Regulation of Fertility (B5)

Organizer(s): Sudhansu K. Dey, Martin M. Matzuk and Kelle H. Moley
February 1 - 6, 2009
Hilton Santa Fe/Historic Plaza  ·  Santa Fe, New Mexico
Abstract Deadline: October 1, 2008
Late Abstract Deadline: October 30, 2008
Scholarship Deadline: October 1, 2008
Early Registration Deadline: December 1, 2008


Supported by the Directors' Fund

The University of Colorado School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The University of Colorado School of Medicine designates this educational activity for a maximum of 28-35 category 1 credits toward the AMA Physician's Recognition Award. Each physician should claim only those credits that he/she actually spent in the activity.

To receive CME credits, mark the box on the registration form, and pay the additional $50.00.



This meeting took place in the 2009 season.

For a complete list of the meetings for the upcoming/current season,
see our meeting list, or search for a meeting.
Summary of Meeting
Sexual reproduction is a complex and highly regulated process essential for successful propagation and diversification of genetic complements, beginning with germ cell development and completing with birth of live young. For successful reproduction, a plethora of events including gametogenesis, ovulation, fertilization, implantation, and placentation requires precise regulation; the success of each go-ahead event is dependent on the accomplishment of the preceding event. Research on these events and their coordination has been translated into clinical practice, particularly for enhancing successes in fertility clinics, controlling gynecological diseases and developing contraceptives. This meeting is designed to bring together a diverse group of leaders, established and rising in the field, who study the complex regulation of reproduction and related developmental processes. The speakers and participants will comprise a group that uses a variety of model systems to better understand the processes relevant to human and animal reproduction and fertility regulation.

Sunday, February 1
3:00 - 7:30 PM Registration Promenade
6:30 - 7:30 PM Refreshments Promenade
7:30 - 8:30 PM Keynote Address Mesa A-B
* Kelle H. Moley, Washington University at St. Louis
Introduction of Keynote Speaker
Janet Rossant, Hospital for Sick Children
Stem Cells and Early Lineage Development
Monday, February 2
7:00 - 8:00 AM Breakfast Chamisa
8:00 - 11:00 AM Meiosis, Germ Cell Renewal and Differentiation Mesa A-B
David C. Page, Whitehead Institute for Biomedical Research
A Combination of Germ-Cell-Intrinsic and Extrinsic Factors Governs Meiotic Initiation in Mouse Embryos
Yumiko Saga, National Institute of Genetics
Nanos2 Promotes Sexual Differentiation of Male Germ Cells
* Tim Schedl, Washington University
Systematic Identification of MPK-1 ERK Substrates Functioning in C. elegans Germ Cell Development
Satoshi Tsukamoto, National Institute of Radiological Sciences
Role of Autophagy during Early Embryogenesis in Mice
9:20 - 9:40 AM Coffee Break Promenade
11:00 AM - On Own for Lunch
11:00 AM - 1:00 PM Poster Setup Mesa C
1:00 - 10:00 PM Poster Viewing Mesa C
4:30 - 5:00 PM Coffee Available Promenade
5:00 - 7:00 PM Female Reproductive Tract Morphogenesis Mesa A-B
* David C. Page, Whitehead Institute for Biomedical Research
Richard R. Behringer, University of Texas MD Anderson Cancer Center
Development of the Female Reproductive Tract
Thomas Edward Spencer, Texas A & M University
Postnatal Uterine Morphogenesis: Strategies and Insights from Domestic Animals
Francesco J. DeMayo, Baylor College of Medicine
Developmental Pathways Regulating Uterine Function
Shinichi Miyagawa, Kumamoto University
Short Talk: Identification of Genetic Cascade for External Genital Development
7:00 - 8:00 PM Social Hour w/ Lite Bites Mesa C
7:30 - 10:00 PM Poster Session 1 Mesa C
Tuesday, February 3
7:00 - 8:00 AM Breakfast Chamisa
7:00 - 8:00 AM Poster Setup Mesa C
8:00 - 11:00 AM Testicular Biology and Fertilization Mesa A-B
* Michael D. Griswold, Washington State University
Kate Loveland, Monash Institute of Medical Research
Activin Signaling in the Testis: Key Target Genes and Physiological Outcomes
Michael D. Griswold, Washington State University
Retinoic Acid and the Cycle of the Seminiferous Epithelium
Erika Matunis, Johns Hopkins University School of Medicine
Stem Cell Niches and Testicular Development
Jurrien Dean, NIDDK, National Institutes of Health
Evolving Paradigms of Sperm-Egg Recognition in Mouse Fertilization
Yeunhee Kim, Cornell University
Short Talk: Production of Donor-Derived Sperm after Spermatogonial Stem Cell Transplantation in the Dog
9:20 - 9:40 AM Coffee Break Promenade
11:00 AM - 12:00 PM Lunch Mesa C
12:00 - 2:30 PM Poster Session 2 Mesa C
12:00 - 5:00 PM Poster Viewing Mesa C
4:30 - 5:00 PM Coffee Available Promenade
5:00 - 7:15 PM Ovarian Biology and Oogenesis Mesa A-B
* Martin M. Matzuk, Baylor College of Medicine
John J. Eppig, The Jackson Laboratory
Signaling Pathways Mediating Oocyte Control of Cumulus Cell Metabolism
Stephanie A. Pangas, Baylor College of Medicne
Signaling through SMAD Proteins in the Ovary
Richard L. Stouffer, Oregon National Primate Research Center
Molecular Analyses of Periovulatory Events in the Primate Follicle: From Microarray Assays to in Vivo Manipulation
Ankur K. Nagaraja, Baylor College of Medicine
Short Talk: MicroRNAs in the Mammalian Ovary and Ovarian Cancer
Agnieszka Jedrusik, Wellcome Trust/Cancer Research UK Gurdon Institute
Short Talk: Role of Cdx2 in Cell Fate Determination
7:15 PM - On Own for Dinner
Wednesday, February 4
7:00 - 8:00 AM Breakfast Chamisa
8:00 - 11:00 AM Preimplantation Biology Mesa A-B
* Kelle H. Moley, Washington University at St. Louis
Energy Metabolism in Preimplantation Embryos
Magdalena Zernicka-Goetz, University of Cambridge
Origins of Pluripotent ICM and Trophectoderm and Molecular Mechanisms behind their Specification
Mellissa Mann, Children's Health Research Institute
Susceptibility of Genomic Imprinting to Assisted Reproductive Technology
Toshihiko Fujimori, National Institute for Basic Biology
Analysis of Cell Behaviors during Preimplantation Mouse Development
Mylene W. M. Yao, Stanford University School of Medicine
Short Talk: The Dynamic Gene Regulatory Network and Reprogramming in the Early Embryo
9:20 - 9:40 AM Coffee Break Promenade
11:00 AM - On Own for Lunch
4:30 - 5:00 PM Coffee Available Promenade
5:00 - 7:00 PM Endocrine Disruptors, Environment and Epigenetics Mesa A-B
* Selvaraj G. Nataraja, EMD Serono Research Institute
Patricia Hunt, Washington State University
Estrogens and the Oocyte: Can Environmental Factors Influence Female Reproductive Potential?
Michael K. Skinner, Washington State University
Epigenetic Transgenerational Actions of Endocrine Disruptors on Reproduction and Disease: The Ghosts in Your Genes
Carmen J. Williams, National Institute of Environmental Health Sciences
Short Talk: Neonatal Genistein Exposure Disrupts Adult Female Reproductive Tract Support of Preimplantation Embryo Development and Implantation
Shannon M. Hawkins, Baylor College of Medicine
Short Talk: The Role of MicroRNAs in Uterine Dysfunction
Jihoon Kim, KAIST
Short Talk: DNA Methylation Status of Imprinted Genes during Human Embryonic Stem Cell Differentiation
7:00 - 8:00 PM Social Hour w/ Lite Bites Mesa C
8:00 - 10:00 PM Workshop: Genetics and Epigenetics of Reproduction Mesa A-B
* Wendy P. Robinson, University of British Columbia
Epigenetic Profiling in the Human Placenta using the Illumina GoldenGate Methylation Panel
Joan K. Riley, Washington University
Inhibition of GAPDH Leads to the Inactivation of S6K1 and Decreased Survival via Elevated ROS Production
Mana Parast, University of California, San Diego
Hypoxia Inhibits PPARgamma-Induced Labyrinthine Differentiation of Mouse Trophoblast Stem Cells
Zhilin Liu, Baylor College of Medicine
Genes in Sterol and Lipid Biosynthetic Pathways are Targets of FSH and FOXO1 Regulation in Granulosa Cells: Evidence from Cells Expressing Mutant Forms of FOXO1
Rebecca Marie Harris, Northwestern University
Identification of Novel Genes Required for Spermatogenesis through Genome-Wide Mutagenesis with N-ethyl-N-nitrosourea
Masahito Ikawa, Osaka University
ER Chaperones and Sperm Fertility
Thursday, February 5
7:00 - 8:00 AM Breakfast Chamisa
8:00 - 11:00 AM Pathways Governing Conceptus-Endometrial Dialogue Mesa A-B
* Sudhansu K. Dey, Cincinnati Children's Hospital Medical Center
John P. Lydon, Baylor College of Medicine
Importance of Steroid Receptor Coregulator-2 in Female Reproductive Biology: Insights from Experimental Mouse Genetics
Haibin Wang, Chinese Academy of Sciences
Lipid Signaling in Embryo-Uterine Crosstalk
Carlos Simon, Fundacion IVI
Pathways Governing Human Endometrial Receptivity
Bruce Murphy, University of Montreal
The Enigma of Embryonic Diapause
Yasushi Hirota, Cincinnati Children's Hospital Medical Center
Short Talk: Uterine Deletion of p53 Confers Compromised Decidualization and Induces Preterm Labor
9:20 - 9:40 AM Coffee Break Promenade
11:00 AM - On Own for Lunch
4:30 - 5:00 PM Coffee Available Promenade
5:00 - 7:15 PM Biology of Placentation Mesa A-B
* Bruce Murphy, University of Montreal
Susan J. Fisher, University of California, San Francisco
Formation of an Immunotolerant Uterine Niche for Human Placental Cytotrophoblasts
Vikki M. Abrahams, Yale University School of Medicine
The Role of Pattern Recognition Receptors in Trophoblast Function
Miguel Constancia, University of Cambridge
Genomic Imprinting, Fetal Growth and the Allocation of Maternal Resources
Manyu Li, University of North Carolina-Chapel Hill
Short Talk: Adrenomedullin Signaling at the Maternal-Fetal Interface
Nathan M. Hunkapiller, University of California, San Francisco
Short Talk: Notch Expression and Function during Placental Vascular Remodeling
7:00 - 8:00 PM Social Hour w/ Lite Bites Mesa C
8:00 - 11:00 PM Entertainment Mesa C
Friday, February 6
Departure
*Session Chair   †Speaker invited, not yet responded.



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