Keystone Symposia | Scientific Conferences on Biomedical and Life Science Topics

Stem Cell Niche Interactions (D5)

Organizer(s): Markus Grompe and Margaret A. Goodell
April 21 - 26, 2009
Fairmont Chateau Whistler · Whistler, British Columbia
Abstract Deadline: December 22, 2008
Late Abstract Deadline: January 26, 2009
Scholarship Deadline: December 22, 2008
Early Registration Deadline: February 23, 2009

Supported by the Directors' Fund

The University of Colorado School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The University of Colorado School of Medicine designates this educational activity for a maximum of 28-35 category 1 credits toward the AMA Physician's Recognition Award. Each physician should claim only those credits that he/she actually spent in the activity.

To receive CME credits, mark the box on the registration form, and pay the additional $50.00.

This meeting took place in the 2009 season.

Listed below are current meetings that are similar to this meeting in nature/content:

Stem Cells in Development, Tissue Homeostasis and Disease (B3)
January 30 - February 4, 2011

For a complete list of the meetings for the upcoming/current season,
see our meeting list, or search for a meeting.

Summary of Meeting
Embryonic stem cells are pluripotent precursors able to differentiate into the many cell types of the body. Adult or tissue stem cells are undifferentiated but lineage specific precursor cells able to proliferate long term while producing daughters that maintain the undifferentiated state (self-renew) and daughters that differentiate into specific cell types. In addition to their intrinsic interest for developmental biology, both kinds of stem cells have great promise for tissue renewal and regenerative medicine. Much has been learned in the past year about the mechanisms that maintain and induce stem cell pluripotency, the mechanisms that control differentiation, and the molecular regulation of stemness and self-renewal. Interactions between stem cells and their niches regulate self-renewal versus differentiation of adult stem cells and key signals from surrounding cells may organize fate decisions in space and time to pattern early embryonic development and differentiation of specific cell types. Understanding of the fundamental biology of embryonic and adult stem cells is being translated into development of “artificial niches” and conditions for controlling cell proliferation and differentiation. This meeting will bring together stem cell scientists from diverse model systems and backgrounds. All career levels will be represented. Current opportunities and challenges in the field will be highlighted in an atmosphere of informal exchange, facilitating new ideas and collaborations towards meeting the next great challenges in the field.

Tuesday, April 21
3:00 - 7:30 PM	Registration	Macdonald Foyer
6:30 - 7:30 PM	Refreshments	Macdonald Foyer
7:30 - 8:30 PM	Keynote Address	Macdonald Ballroom
	* Markus Grompe, Oregon Health & Science University
	Sean J. Morrison, HHMI/University of Michigan The Regulation of Hematopoietic Stem Cell Self-Renewal
Wednesday, April 22
7:00 - 8:00 AM	Breakfast	Macdonald Ballroom
8:00 - 11:15 AM	Control of Stem Cell Differentiation	Macdonald Ballroom
	* James A. Thomson, Morgridge Institute for Research, University of Wisconsin
	Deepak Srivastava, Gladstone Institute of Cardiovascular Disease MicroRNA Regulation of Cardiac Cell Fate Decisions
	Ronald D. McKay, National Institutes of Health Neural Lineages
	Didier Y. R. Stainier, University of California, San Francisco Endodermal Organ Development and Regeneration in Zebrafish

	Gordon M. Keller, University Health Network, MaRS Centre Cardiovascular Development from Mouse and Human Pluripotent Stem Cells

	Jolly Mazumdar, University of Pennsylvania Short Talk: O2 Regulates Stem Cells through Wnt/beta-catenin Signaling
	Fabio Rossi, University of British Columbia Short Talk: Muscle Injury Activates Fibro/Adipogenic Progenitors that Provide a Transient Pro-Differentiation Niche for Myogenic Cells
9:20 - 9:40 AM	Coffee Break	Macdonald Foyer
11:15 AM -	On Own for Lunch
11:15 AM - 1:00 PM	Poster Setup	Macdonald Ballroom
1:00 - 10:00 PM	Poster Viewing	Macdonald Ballroom
4:30 - 5:00 PM	Coffee Available	Macdonald Foyer
5:00 - 7:00 PM	Novel Sources of Pluripotent Cells	Macdonald Ballroom
	* Ronald D. McKay, National Institutes of Health
	Shoukrat Mitalipov, Oregon Health & Science University Pluripotent Stem Cells Derived by Somatic Cell Nuclear Transfer and Parthenogenesis



	Timm Schroeder, Helmholtz Center Munich Tracking Stem Cell Behavior at the Single Cell Level: New Tools for Old Questions
	James A. Thomson, Morgridge Institute for Research, University of Wisconsin Human Induced Pluripotent Stem Cells Derived with Episomal Vectors


	Robert David, University Munich Short Talk: Generation of Distinct Cardiovascular Cell Types from Pluripotent Stem Cells via Directed Forward Programming
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Macdonald Ballroom
7:30 - 10:00 PM	Poster Session 1	Macdonald Ballroom
Thursday, April 23
7:00 - 8:00 AM	Breakfast	Macdonald Ballroom
7:00 - 8:00 AM	Poster Setup	Macdonald Ballroom
8:00 - 11:15 AM	Transcriptional and Epigenetic Regulation of Embryonic Stem Cell Fate	Macdonald Ballroom
	* Gordon M. Keller, University Health Network, MaRS Centre

	Yehudit Bergman, Hebrew University, Hadassah Medical School Silencing of Embryonically-Specific Genes
	Paul A. Khavari, Stanford University Epigenetic Regulation of Epidermal Self-Renewal and Differentiation
	Thomas P. Zwaka, Baylor College of Medicine Ronin Controls a Unique Genetic Program Involved in the Perpetuity of Mouse Embryonic Stem Cells
	Robert E. Braun, The Jackson Laboratory Short Talk: The Germline Stem Cell Niche Is Required for Fetal Stem Progenitor Cells and for Teratoma Formation
	Cedric Blanpain, Université Libre de Bruxelles Short Talk: Identification of the Cell Lineage at the Origin of Basocelullar Carcinoma
9:20 - 9:40 AM	Coffee Break	Macdonald Foyer
11:15 AM - 12:00 PM	Lunch	Macdonald Ballroom
12:00 - 2:30 PM	Poster Session 2	Macdonald Ballroom
12:00 - 7:00 PM	Poster Viewing	Macdonald Ballroom
4:30 - 5:00 PM	Coffee Available	Macdonald Foyer
5:00 - 7:00 PM	Asymmetric Cell Division	Macdonald Ballroom
	* Allan C. Spradling, Howard Hughes Medical Institute/Carnegie Institute
	Chris Q. Doe, University of Oregon Intrinsic and Extrinsic Cues Regulating Neuroblast ACD

	Yukiko M. Yamashita, University of Michigan, Ann Arbor Asymmetric Stem Cell Divisions in the Drosophila Testis
	Shahragim Tajbakhsh, Institut Pasteur Skeletal Muscle Stem Cell Properties and Polarized Cell Divisions
	Ellen J. Ward, University of Washington Short Talk: bantam miRNA is Required for Germline Stem Cell Division and Maintenance in the Drosophila Ovarian Niche
7:00 PM -	On Own for Dinner
Friday, April 24
7:00 - 8:00 AM	Breakfast	Macdonald Ballroom
8:00 - 11:00 AM	Tissue Specific Stem Cells I	Macdonald Ballroom

	* Timm Schroeder, Helmholtz Center Munich
	Stephen Badylak, University of Pittsburgh Biologic Scaffolds to Recreate the Regenerative Niche

	Jill Helms, Stanford University School of Medicine Enhancing Bone Healing via Wnt-Protein Mediated Activation of Endogenous Stem Cells
	Helen M. Blau, Stanford University Adult Stem Cell Behavior in Bioengineered Niches
	Hans C. Clevers, Hubrecht Institute Wnt, Lgr5 Stem Cells and Colon Cancer
	Hans-Willem E. Snoeck, Mount Sinai School of Medicine Short Talk: Quantitative Traits in Hemotopoiesis
9:20 - 9:40 AM	Coffee Break	Macdonald Foyer
11:00 AM -	On Own for Lunch
11:00 AM - 1:00 PM	Poster Setup	Macdonald Ballroom
1:00 - 10:00 PM	Poster Viewing	Macdonald Ballroom
4:30 - 5:00 PM	Coffee Available	Macdonald Foyer
5:00 - 7:00 PM	Clinical Applications of Stem Cells and Artificial Niches	Macdonald Ballroom
	* Helen M. Blau, Stanford University
	Markus Grompe, Oregon Health & Science University Regeneration in the Adult Liver: Stem Cells or Mature Hepatocytes?
	Yann Barrandon, École Polytechnique Fédérale de Lausanne Manipulating Epithelial Stem Cell Potency

	Aileen Anderson, University of California, Irvine Stem Cell Transplantation in Spinal Cord Injury
	Eric Lagasse, University Of Pittsburgh Short Talk: Rescue of Lethal Hepatic Failure by Functional Ectopic Liver in Lymph Nodes
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Macdonald Ballroom
7:30 - 10:00 PM	Poster Session 3	Macdonald Ballroom
Saturday, April 25
7:00 - 8:00 AM	Breakfast	Macdonald Ballroom
8:00 - 11:00 AM	Tissue Specific Stem Cells II	Macdonald Ballroom
	* Haifan Lin, Yale University
	Allan C. Spradling, Howard Hughes Medical Institute/Carnegie Institute The Dynamic Follicle Stem Cell Niche
	Shosei Yoshida, National Istitute for Basic Biology Spermatogenic Stem Cell System and its Niche in the Mouse Testis


	Margaret A. Goodell, Baylor College of Medicine Regulation of Hematopoietic Stem Cells
	Chutima Noi Talchai, Columbia University Short Talk: Foxo1 Controls Renewal of Pancreatic Endocrine Progenitors, and Beta Cell Formation
	Tudorita (Doina) Tumbar, Cornell University Short Talk: Distinct Self-Renewal and Differentiation Phases in the Niche of Infrequently Dividing Hair Follicle Stem Cells
9:20 - 9:40 AM	Coffee Break	Macdonald Foyer
11:15 AM -	On Own for Lunch
4:30 - 5:00 PM	Coffee Available	Macdonald Foyer
5:00 - 7:00 PM	Non-Coding RNAs and Cell Fate Control	Macdonald Ballroom
	* Margaret A. Goodell, Baylor College of Medicine
	Haifan Lin, Yale University Piwis and piRNAs in Germline Stem Cell Development
	Soo-Kyung Lee, Baylor College of Medicine The Role of microRNAs and Small C-Terminal Phosphatases in Nervous System Development
	Linheng Li, Stowers Institute for Medical Research Real Time Imaging the Functional HSC Niche
	Xuting Rebecca Sheng, Johns Hopkins School of Medicine Short Talk: Live Imaging of Drosophila Spermatogonia Dedifferentiating into Germline Stem Cells
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Macdonald DEF
8:00 - 11:00 PM	Entertainment	Macdonald DEF
Sunday, April 26
	Departure

*Session Chair †Speaker invited, not yet responded.