Keystone Symposia | Scientific Conferences on Biomedical and Life Science Topics

Omics Meets Cell Biology (B2)

Organizer(s): Ruedi H. Aebersold and Tony Pawson
January 25 - 30, 2009
Beaver Run Resort · Breckenridge, Colorado
Abstract Deadline: September 25, 2008
Late Abstract Deadline: October 28, 2008
Scholarship Deadline: September 25, 2008
Early Registration Deadline: November 25, 2008

Sponsored by Bristol-Myers Squibb Company and Novartis Institutes for BioMedical Research

This meeting took place in the 2009 season.

Listed below are current meetings that are similar to this meeting in nature/content:

Omics Meets Cell Biology (E1)
May 8 - 13, 2011

For a complete list of the meetings for the upcoming/current season,
see our meeting list, or search for a meeting.

Summary of Meeting
Apart from deciphering the genomic sequences of hundreds of species, the (human) genome project has catalyzed a wave of technological innovation that is unprecedented in the life sciences. Among its most important products are a number of assays or technologies for the quantitative, global and high throughput analysis of the genome, the molecules derived from the genome and their interactions. These technologies are colloquially described as “OMICS” technologies. The data sets generated by OMICS technologies represent a unique resource for biologists. They have also raised a number of challenging technical and conceptual issues, the solutions to which will ultimately determine the impact of OMICS technologies on biology. These include the error models, completeness and reproducibility of large scale data sets, the question whether and how different data types obtained from the same systems can be integrated and, most importantly, whether validated new biological knowledge has been or will be created either from OMICS data alone or by strategies that combine OMICS and traditional approaches. This conference will bring together the leading experts representing OMICS technologies and leading cell biologists to discuss these issues.

Sunday, January 25
3:00 - 7:30 PM	Registration	Foyer
6:30 - 7:30 PM	Refreshments	Foyer
7:30 - 9:30 PM	Keynote Session	Peak 5
	* Tony Pawson, Samuel Lunenfeld Research Institute
	Marc W. Kirschner, Harvard Medical School Robustness in Biology
	David B. Searls, GlaxoSmithKline Pharmaceuticals Omic Empiricism
Monday, January 26
7:00 - 8:00 AM	Breakfast	Summit Gallery
8:00 - 11:00 AM	Omics and Signaling I	Peak 5
	Tony Pawson, Samuel Lunenfeld Research Institute Signaling Networks: Bidirectional Cellular Communication
	* Rudolf H. Aebersold, Institute of Molecular Systems Biology, ETH Zurich Kinase-Substrate Networks
	Ernst Hafen, Institute of Molecular Systems Biology, ETH Zurich Control of Cell Growth
	Benjamin Cosgrove, Stanford University Multi-Variate Analysis of Signaling Networks Governing Cell Phenotypic Behaviour: Applications to Hepatocyte Toxicity and Pathology

9:20 - 9:40 AM	Coffee Break	Foyer
11:00 AM -	On Own for Lunch
11:00 AM - 1:00 PM	Poster Setup	Peaks 1-4
1:00 - 10:00 PM	Poster Viewing	Peaks 1-4
4:30 - 5:00 PM	Coffee Available	Foyer
5:00 - 7:00 PM	Omics and Signaling II	Peak 5
	Jennifer Mummery Widmer, Institute of Molecular Biotechnology, Austrian Academy of Sciences Short Talk: Genome-Wide Analysis of Notch Signaling during Drosophila External Sensory Organ Development by Transgenic RNAi

	Sarah Teichmann, MRC Laboratory of Molecular Biology Evolution of Protein Complexes and Protein Interaction Networks
	* Edward A. Dennis, University of California, San Diego Lipid Metabolomics and Cell Signaling
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Peaks 1-4
7:30 - 10:00 PM	Poster Session 1	Peaks 1-4
Tuesday, January 27
7:00 - 8:00 AM	Breakfast	Summit Gallery
7:00 - 8:00 AM	Poster Setup	Peaks 1-4
8:00 - 11:00 AM	Omics and Sub-Cellular Organization I	Peak 5
9:20 - 9:40 AM	Coffee Break	Foyer
11:00 AM - 12:00 PM	Lunch	Peaks 1-4
12:00 - 2:30 PM	Poster Session 2	Peaks 1-4
2:30 - 4:30 PM	Workshop: Available Bioinformatics Resources for Cell Biologists	Peak 5

	Scott R. Floyd, Beth Israel Deaconess Medical Center, Harvard Medical School Using Advanced Image Analysis Methods in High-Throughput Image-Based Screens for DNA Damage
	Gary Bader, University of Toronto Biological Network Visualization and Analysis using Cytoscape and Pathway Commons
	* Rolf Apweiler, European Bioinformatics Institute Databases and their Utility
	Olga Vitek, Purdue University Experimental Design from a Statistics Point of View
4:30 - 5:00 PM	Coffee Available	Foyer
5:00 - 7:00 PM	Omics and Sub-Cellular Organization II	Peak 5

	* Wolfgang P. Baumeister, Max Planck Institute of Biochemistry Cryo-Electron Microscopy: From Molecules to Systems
	Peer Bork, European Molecular Biology Laboratory Databases/Data Integration/Computational Biology
	Oliver Hantschel, Research Center for Molecular Medicine of the Austrian Academy of Sciences Short Talk: Interaction Proteomic, Chemical Proteomic and Transcriptomic Analysis of Abl Oncoproteins and their Inhibitors
7:00 PM -	On Own for Dinner
Wednesday, January 28
7:00 - 8:00 AM	Breakfast	Summit Gallery
8:00 - 11:00 AM	Omics and Cell Metabolism I	Peak 5
	* Stephen G. Oliver, Cambridge University Identifying Functional Modules using Metabolic Models

	Garry P. Nolan, Stanford University Diseased Signaling Networks at the Single Cell Level
	Uwe Sauer, Institute of Molecular Systems Biology, ETH Zurich Unraveling Condition-Specific Networks of Active Metabolic Regulation
	Trey G. Ideker, University of California, San Diego Mapping Gene Regulatory Pathways by Assembly of Physical and Genetic Interactions
	Marta M. Lipinski, Harvard Medical School Short Talk: A Genome-Wide Image-Based Screen Identifies Global Molecular Mechanisms Regulating Mammalian Autophagy
9:20 - 9:40 AM	Coffee Break	Foyer
11:00 AM -	On Own for Lunch
11:00 AM - 1:00 PM	Poster Setup	Peaks 1-4
1:00 - 10:00 PM	Poster Viewing	Peaks 1-4
4:30 - 5:00 PM	Coffee Available	Foyer
5:00 - 7:00 PM	Omics Experimental and Computational Strategies I	Peak 5


	David M. Sabatini, Whitehead Institute for Biomedical Research Large Scale Loss of Function Screens in Mammalian Cells
	Sabine P. Cordes, Mount Sinai Hospital The Mouse and the OMICS of Happiness
	* Cheryl H. Arrowsmith, Ontario Cancer Institute Integrating Structural Genomics and Chemical Genomics for Biology and Medicine
	Shohei Koide, University of Chicago Short Talk: Affinity Clamps: Next-Generation Affinity Reagents
7:00 - 8:00 PM	Social Hour w/ Lite Bites	Peaks 1-4
7:30 - 10:00 PM	Poster Session 3	Peaks 1-4
Thursday, January 29
7:00 - 8:00 AM	Breakfast	Summit Gallery
8:00 - 11:00 AM	Omics and DNA Damage/Cell Cycle Research	Peak 5
	Stephen J. Elledge, Harvard-Partners Center for Genetics and Genomics Integrative Approaches for DNA Damage and Cell Cycle Analysis

	* Michael Snyder, Stanford University School of Medicine Identifying Regulators of Neuronal Differentiation by High-Throughput Screening of Embryonic Stem Cells

	Daniel Durocher, Samuel Lunenfeld Research Institute, Mount Sinai Hospital High Content-High Throughput Screens to Probe the Cellular Response to DNA Damage
	Joan S. Brugge, Harvard Medical School Mining the Genome for Regulators of Cell Migration
	Steven P. Gygi, Harvard Medical School Short Talk: Combining Chemical Genetics with Phosphoproteomics: Identifying Direct Cdk1 Targets in Yeast
9:20 - 9:40 AM	Coffee Break	Foyer
11:00 AM -	On Own for Lunch
4:30 - 5:00 PM	Coffee Available	Foyer
5:00 - 7:00 PM	Omics Experimental and Computational Strategies II	Peak 5
	Christian von Mering, University of Zurich The STRING Protein Network Resource: Data Integration for Systems Biology
	Timothy R. Hughes, University of Toronto Function and Evolution of Transcriptional Networks



	* Marian Walhout, University of Massachusetts Medical School Gene-Centered Regulatory Networks

	Peter V. Hornbeck, Cell Signaling Technology Short Talk: PhosphoSitePlus: A Resource Enabling both System-Wide and Reductionist Studies of Post-translational Modifications
	Rene H. Medema, University Medical Center Utrecht Short Talk: Omics Meets Motor Proteins on the Spindle
7:00 - 8:00 PM	Summary Discussion with Lite Bites	Peaks 1-4
8:00 - 11:00 PM	Entertainment	Peaks 1-4
Friday, January 30
	Departure

*Session Chair †Speaker invited, not yet responded.