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Obesity: Novel Aspects of the Regulation of Body Weight (J4)

Organizer(s): Randy J. Seeley, Mark W. Sleeman and I. Sadaf Farooqi
January 20 - 25, 2009
Fairmont Banff Springs  ·  Banff, Alberta
Abstract Deadline: September 23, 2008
Late Abstract Deadline: October 23, 2008
Scholarship Deadline: September 23, 2008
Early Registration Deadline: November 20, 2008


Supported by the Directors' Fund

The University of Colorado School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The University of Colorado School of Medicine designates this educational activity for a maximum of 28-35 category 1 credits toward the AMA Physician's Recognition Award. Each physician should claim only those credits that he/she actually spent in the activity.

To receive CME credits, mark the box on the registration form, and pay the additional $50.00.


Joint meeting: Type 2 Diabetes and Insulin Resistance (J3)
NOTE: Registration for meeting allows attendance at joint meeting (pending space availability).



This meeting took place in the 2009 season.

For a complete list of the meetings for the upcoming/current season,
see our meeting list, or search for a meeting.
Summary of Meeting
Obesity remains among the most daunting health problems facing the developed world. Despite the rising prevalence of obesity, the biological systems that serve to match caloric intake to caloric expenditure are robust and make permanent weight loss difficult to achieve. Current research points to a multitude of factors that contribute to this regulation. Identifying the processes that are most amenable for therapeutic intervention is a crucial research goal. To that end, this conference will focus on the latest work identifying novel genes, hormones and signaling cascades that regulate energy balance. The program will also emphasize a wide range of new strategies for using this new information to produce safe and effective therapies to prevent or treat obesity.

Tuesday, January 20
3:00 - 7:30 PM Registration Van Horne Foyer
6:30 - 7:30 PM Refreshments Van Horne Foyer
7:30 - 8:30 PM Keynote Address (Joint) Van Horne Ballroom A,B
Bruce M. Spiegelman, Harvard Medical School
Transcriptional Control of Adipogenesis and Energy Balance
Wednesday, January 21
7:00 - 8:00 AM Breakfast Mezzanine 2
8:00 - 11:15 AM Genetics of Obesity and Diabetes (Joint) Van Horne Ballroom A,B
* Randy J. Seeley, University of Cincinnati
Philippe Froguel, Imperial College of London
GWA Enlighten Obesity and Diabetes Physiology
Jeffrey M. Friedman, Rockefeller University
Talk Title to be Determined
Eric Schadt, Pacific Biosciences
In silico Alternatives to Association Studies
Andrew Hattersley, Peninsula Medical School
What have we Learnt from Finding the BMI and Obesity Gene FTO?
Satya Dash, University of Cambridge
Short Talk: An Inherited Disorder of Glucose Transporter 4 Translocation in a Family with Acanthosis Nigricans, Post-prandial Hyperinsulinemia and a Truncation Mutation in TBC1D4
Cecilia Lindgren, Oxford University
Short Talk: Analysis of Genome-Wide Scans Identifies Potential Novel Common Susceptibility Loci for Central Obesity
9:20 - 9:40 AM Coffee Break Van Horne Foyer
11:15 AM - On Own for Lunch
11:15 AM - 1:00 PM Poster Setup Mezzanine 2
1:00 - 10:00 PM Poster Viewing Mezzanine 2
4:30 - 5:00 PM Coffee Available Van Horne Foyer
5:00 - 7:00 PM New Advances in CNS Regulation of Energy Balance Van Horne Ballroom C
* Kevin L. Grove, Oregon National Primate Research Center
Mathias Treier, European Molecular Biology Organisation
A Bsx Positive Hypothalamic Neuronal Network Regulates Locomotory Behaviour and Food Intake
Anthony R. Means, Duke University
Hypothalamic CaMKK2 Contributes to the Regulation of Energy Balance
Lori M. Zeltser, Columbia University
Ontogeny of Neuronal Lineages in the Arcuate Nucleus
Frank Thomas Wunderlich, Institute for Genetics Cologne
Short Talk: Enhanced Stat3 Activation in POMC Neurons Provokes Negative Feedback Inhibition of Leptin and Insulin Signaling in Obesity
7:00 - 8:00 PM Social Hour w/ Lite Bites Mezzanine 2
7:30 - 10:00 PM Poster Session 1 Mezzanine 2
Thursday, January 22
7:00 - 8:00 AM Breakfast Mezzanine 2
7:00 - 8:00 AM Poster Setup Mezzanine 2
8:00 - 11:15 AM Insulin Resistance and Lipotoxicity (Joint) Van Horne Ballroom A,B
* Kitt F. Petersen, Yale University School of Medicine
Gerald I. Shulman, Howard Hughes Medical Institute, Yale University School of Medicine
Molecular Mechanisms of Insulin Resistance
Jay D. Horton, University of Texas Southwestern Medical Center
Hepatic Steatosis and SREBP Pathway
Sonia Caprio, Yale University School of Medicine
Ectopic Fat Distribution and Insulin Resistance in Obese Adolescents: Does it Matter?
Ronald M. Evans, The Salk Institute
Nuclear Receptors: Engineering Metabolism to Enhance Athletic Performance
Qunfeng Jiang, Karolinska Institutet
Short Talk: In-vivo Metabolic Studies in Muscle-Specific Calcineurin Transgenic Mice
Christopher L. Karp, Cincinnati Children's Hospital Research Foundation
Short Talk: Regulation of Energy Metabolism by the RP105/TLR Axis
9:20 - 9:40 AM Coffee Break Van Horne Foyer
11:15 AM - 12:00 PM Lunch Mezzanine 2
12:00 - 2:30 PM Poster Session 2 Mezzanine 2
12:00 - 5:00 PM Poster Viewing Mezzanine 2
4:30 - 5:00 PM Coffee Available Van Horne Foyer
5:00 - 7:00 PM The Role of Vasculature in the Development and Treatment of Obesity Van Horne Ballroom C
* Herbert Herzog, Garvan Institute
Gavin Thurston, Regeneron
Regulation of Angiogenesis
Maria Ann Rupnick, Children's Hospital/Brigham & Women's Hospital
Angiogenic Inhibitors to Treat Obesity
Randy J. Seeley, University of Cincinnati
William R. Munday, TSRI
Short Talk: Novel Mechanism of Adipogenesis: Linking Stress and NPY to Progenitor Cells
7:00 PM - On Own for Dinner
Friday, January 23
7:00 - 8:00 AM Breakfast Mezzanine 2
8:00 - 11:00 AM Developmental and Epigenetic Determinants of Obesity Van Horne Ballroom C
* Yoshihiro Ogawa, Medical Research Institute, Tokyo Medical and Dental University
Emma Whitelaw, Queensland Institute of Medical Research
How Lifetime Influences Epigenotype within and across Generations
Jonathan R. Seckl, University of Edinburgh School of Clinical Sciences & Community Health
In Utero Glucocorticoid ‘Programming’ of Metabolic Syndrome Risk
Kevin L. Grove, Oregon National Primate Research Center
Development of Neuropeptide Systems that Regulate Metabolism
Clive W. Coen, King's College London
Short Talk: Developmental Programming of Appetite and Obesity: Role of Leptin
9:20 - 9:40 AM Coffee Break Van Horne Foyer
11:00 AM - On Own for Lunch
11:00 AM - 1:00 PM Poster Setup Mezzanine 2
1:00 - 10:00 PM Poster Viewing Mezzanine 2
4:30 - 5:00 PM Coffee Available Van Horne Foyer
5:00 - 7:00 PM Are We What We Eat? Metabolic Regulation of Energy Balance Van Horne Ballroom C
* I. Sadaf Farooqi, University of Cambridge
Christopher B. Newgard, Duke University Medical Center
Mechanisms of Nutritional Modulation of Insulin Action
Eleftheria Maratos-Flier, Beth Israel Deaconess Medical Center
Molecular Insights from the Study of Ketogenic Diets -- The Role of FGF21 in Metabolism
Steven A. Kliewer, University of Texas Southwestern Medical Center
Regulation of Metabolism by Endocrine FGFs
Zivjena Vucetic, University of Pennsylvannia
Short Talk: Epigenetic Reprogramming of Dopaminergic Reward Circuitry by Pre- and Postnatal Diet
7:00 - 8:00 PM Social Hour w/ Lite Bites Mezzanine 2
7:30 - 10:00 PM Poster Session 3 Mezzanine 2
Saturday, January 24
7:00 - 8:00 AM Breakfast Mezzanine 2
8:00 - 11:15 AM Advances in Treatment and Therapeutic Intervention in Obesity and Diabetes (Joint) Van Horne Ballroom A,B
9:20 - 9:40 AM Coffee Break Van Horne Foyer
11:15 AM - On Own for Lunch
4:30 - 5:00 PM Coffee Available Van Horne Foyer
5:00 - 7:00 PM New Ways in which the Gut Regulates Metabolic Functions Van Horne Ballroom C
* Lee M. Kaplan, Massachusetts General Hospital
Mark W. Sleeman, Regeneron Pharmaceuticals Inc.
Gut Hormones and the Regulation of Metabolism
Matthias H. Tschöp, University of Cincinnati
The Gut-Brain Axis in the Control of Peripheral Metabolic Processes
Daniel J. Drucker, Banting and Best Diabetes Centre
The GLP-2R; An Essential Mediator of Energy Absorption
Gilles Mithieux, Institut National de la Santé et de la Recherche Médicale INSERM
Short Talk: Intestinal Gluconeogenesis is a Key in Insulin Sensitivity after Gastric Bypass in Mice
7:00 - 8:00 PM Social Hour w/ Lite Bites Mezzanine 2
8:00 - 11:00 PM Entertainment Mezzanine 2
Sunday, January 25
Departure
*Session Chair   †Speaker invited, not yet responded.



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