This meeting took place in 2014



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Innate Immunity, Metabolism and Vascular Injury (X8)


Organizer(s) Ajay Chawla, Peter Tontonoz and Gwendalyn J. Randolph
March 23—28, 2014
Whistler Conference Centre • Whistler, British Columbia Canada
Discounted Abstract Deadline: Nov 21, 2013
Abstract Deadline: Dec 19, 2013
Scholarship Deadline: Nov 21, 2013
Discounted Registration Deadline: Jan 23, 2014

Supported by an educational donation provided by Amgen


Summary of Meeting:
A chronic low-grade inflammatory response is a defining feature of various metabolic diseases, including atherosclerosis, obesity, and type 2 diabetes. This smoldering inflammation in tissues, whether it is in the vascular bed, white adipose tissue or perivascular fat, is primarily mediated by the innate immune system. Consequently, this Keystone Symposium on Innate Immunity, Metabolism and Vascular Injury will bring together leading investigators in areas of macrophage biology, vascular inflammation, atherosclerosis, and obesity-induced metabolic disease. Sessions will encompass a broad range of topics highlighting the importance of and mechanisms by which innate immunity contributes to progression of metabolic diseases, including monocyte development and trafficking, macrophage activation in vascular bed and adipose tissues, and systems biology of myeloid cells. Exciting new developments in sensing of metabolic stress by inflammasomes, clearance of apoptotic cells by macrophages, and initiation of necrotic cell death programs will also be discussed. These basic studies will be complemented by talks discussing new strategies for promoting plaque regression, and targeting innate inflammation to treat insulin resistance, type 2 diabetes, and coronary artery disease.

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Scholarships/Awards

Biogen Scholarship Recipients

Dario A. Gutierrez
MRL Cambridge ESC, USA

Biogen Idec ECITA Scholarship Recipients

Michelle T. Foster
Colorado State University, USA

National Heart, Lung, and Blood Institute (NHLBI) Scholarship Recipients

Amy M. Archer
Northwestern University, USA

Partha Dutta
Massachusetts General Hospital Harvard Medical School, USA

José J. Fuster
Boston University School of Medicine, USA

Xin Rong
HHMI/University of California, Los Angeles, USA

Rachel J. Roth-Flach
Pfizer Inc., USA

Miyako Tanaka
Nagoya University, Japan

Jan Van den Bossche
Academic Medical Center, Netherlands

A. Phillip West
Yale University School of Medicine, USA