Keystone Resort Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

This meeting took place in 2010


Here are the related meetings in 2017:
Molecular Mechanisms of Heart Development (X7)

For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Cardiovascular Development and Repair (X2)


Organizer(s) Doris A. Taylor and Brian H. Annex
February 28—March 5, 2010
Keystone Resort • Keystone, Colorado USA
Abstract Deadline: Oct 28, 2009
Late Abstract Deadline: Nov 30, 2009
Scholarship Deadline: Oct 28, 2009
Early Registration Deadline: Dec 28, 2009

Sponsored by Gilead Sciences, Inc.


Summary of Meeting:
During fetal development, cardiocytes and vascular progenitors proliferate, coalesce and organize to form a nascent organ. Yet during adult mammalian life, these same cells are incapable of responding to repair injured heart. This Keystone Symposia meeting is designed: 1) to expose scientists in the field of cardiac and vascular repair to models of successful cardiac repair in lower vertebrates, 2) to discuss repair in the context of cardiac development and 3) to begin to ask what cues and targets from each may be applicable in the adult mammal. As a companion to and overlapping with an Angiogenesis meeting, it will provide meeting-goers access to both preclinical and clinical components of cardiac and vascular repair using cells, genes and small molecules.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


SUNDAY, FEBRUARY 28

15:00—19:30
Registration

Longs Peak Foyer
18:30—19:30
Refreshments

Longs Peak Foyer
19:30—20:30
Keynote Address (Joint)
Meeting has ended...abstracts no longer viewable online.

Grays/Longs Peaks
* Michael Simons, Yale University, USA

* Doris A. Taylor, Texas Heart Institute, USA

Eric N. Olson, University of Texas Southwestern Medical Center, USA
MicroRNA Control of Cardiovascular Development and Disease


MONDAY, MARCH 1

07:00—08:00
Breakfast

Quandary Peak
08:00—11:15
Cardiac Development as a Model for Repair
Meeting has ended...abstracts no longer viewable online.

Longs Peak
* Doris A. Taylor, Texas Heart Institute, USA

Richard P. Harvey, University of New South Wales, Victor Chang Cardiac Research Institute, Australia
The Pericyte Continuum in Heart Development and Repair

Paul R. Riley, University of Oxford, UK
Epicardium-Induced Coronary Development and Repair

Nadia A. Rosenthal, The Jackson Laboratory, USA
Epicardium: The Outer Limits of Stem Cells

Gordon M. Keller, University Health Network, MaRS Centre, Canada
Cardiovascular Development from Human Pluripotent Stem Cells

Santanu Chakraborty, Cincinnati Children's Research Foundation, USA
Short Talk: Twist1 Overexpression Promotes Heart Valve Cell Proliferation and Alters Extracellular Matrix Remodeling whereas Tbx20 Overexpression Causes Abnormal Heart Valve Primordia Formation in vivo in Mice


Following Session is for Angiogenesis in Health and Disease (X1)

08:00—11:00
Arterial Specification
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* Eli Keshet, Hebrew University, Israel

Nathan Lawson, University of Massachusetts Medical School, USA
Exploring Endothelial Diversity in the Zebrafish

Michael Simons, Yale University, USA
Arterial Specification Signaling Cascade

Brian L. Black, University of California, San Francisco, USA
A Combinatorial Transcriptional Code for Endothelial Development

Tao P. Zhong, Vanderbilt University, USA
Regulation of Arterial-Venous Cell Specification and Migration

Xabier Lopez Aranguren, Katholieke Universiteit Leuven, Belgium
Short Talk: The Nuclear Orphan Receptor COUP-TFII Plays an Essential Role in Establishing and Maintaining Venous and Lymphatic Endothelial Identity by Distinct Mechanisms

09:20—09:40
Coffee Break

Longs Peak Foyer
11:15
On Own for Lunch and Recreation

11:15—13:00
Poster Setup

Quandary Peak
13:00—22:00
Poster Viewing

Quandary Peak
16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Models of Successful Cardiac Repair
Meeting has ended...abstracts no longer viewable online.

Longs Peak
* Nadia A. Rosenthal, The Jackson Laboratory, USA

Eduardo Marban, Cedars-Sinai Medical Center, USA
Cardiac Cell Therapy: From Concept to Clinical Reality

Kenneth D. Poss, Duke University Medical Center, USA
Heart Regeneration in Zebrafish

Walter J. Koch, Temple University School of Medicine, USA
Using Gene Therapy to Repair the Failing Heart

Maria Paola Santini, Heart Science Centre, NHLI, Imperial College London, UK
Short Talk: Cells and Factors for Cardiac Regeneration: mIGF-1-Mediated Cross-Talk between the Heart and the Bone Marrow


Following Session is for Angiogenesis in Health and Disease (X1)

17:00—19:00
Vascular Metabolomics
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* Kenneth Walsh, Boston University School of Medicine, USA

Ulf P.E. Eriksson, Karolinska Institutet, Sweden
Vascular Endothelial Growth Factor B Controls Endothelial Fatty Acid Uptake - Implications in Fatty Acid Metabolism

Frank J. Giordano, Yale University, USA
Role of HIFs in Metabolic Regulation

Stéphane E. Germain, INSERM, France
Short Talk: Protection Against Myocardial Infarction through Preservation of Vascular Endothelial Cell Barrier Integrity and Reduction of No-Reflow by Angiopoietin-like 4

19:00—20:00
Social Hour with Lite Bites

Quandary Peak
19:30—22:00
Poster Session 1

Quandary Peak

TUESDAY, MARCH 2

07:00—08:00
Breakfast

Quandary Peak
08:00—11:00
Aging Cardiocytes and Matrix - Molecular Targets for Repair
Meeting has ended...abstracts no longer viewable online.

Longs Peak
* Eduardo Marban, Cedars-Sinai Medical Center, USA

Jeffery D. Molkentin, Cincinnati Children's Hospital Medical Center, USA
TRPC Channels Underlie Muscle Degeneration and Hypertrophy in Response to Alterations in the ECM - Sarcolemma

Jeffrey N. Keller, Pennington Biomedical Research Center, USA
Aging and Diet Effects on Proteasome and Oxidative Stress in the Heart

R. John Solaro, University of Illinois at Chicago, USA
Quantitative Comparison of Sarcomeric Phosphoproteomes of Neonatal and Adult Rat Hearts

Kyoko Imanaka-Yoshida, Mie University, Graduate School of Medicine, Japan
Tenascin-C as a Target for Regulation of Cardiac Remodeling

Arti Anushka Ramkisoensing, Leiden University Medical Center, Netherlands
Short Talk: Embryonic and Fetal Mesenchymal Stem Cells do Undergo Cardiac Differentiation in Contrast to their Adult Counterparts: The Younger the Better


Following Session is for Angiogenesis in Health and Disease (X1)

08:00—11:15
Endothelial Cell-Tissue Interactions
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* Nathan Lawson, University of Massachusetts Medical School, USA

Eli Keshet, Hebrew University, Israel
On-Site Education by VEGF of Recruited Monocytes

Kenneth Walsh, Boston University School of Medicine, USA
Paracrine Endothelium-Myocyte Interactions

Didier Y. R. Stainier, Max Planck Institute for Heart and Lung Research, Germany
Endothelial Cell-Tissue Interactions during Zebrafish Organogenesis

Maija Bry, University of Helsinki, Finland
VEGF-B Induces VEGFR-1 and Bmx Tyrosine Kinase-Mediated Cardiac Hypertrophy and Strong Coronary Arteriogenesis in Rats

Christiana Ruhrberg, University College London, UK
Macrophages Act as Cellular Chaperones for Vascular Anastomosis

09:20—09:40
Coffee Break

Longs Peak Foyer
11:00
On Own for Lunch and Recreation

11:00—13:00
Poster Setup

Quandary Peak
13:00—22:00
Poster Viewing

Quandary Peak
14:30—16:30
Workshop: Conversations on Deriving and Differentiating Stem Cells for Cardiac Repair

Longs Peak
* Doris A. Taylor, Texas Heart Institute, USA

14:30—15:30
Deriving Stem Cells

Longs Peak
Stefan Braam, Leiden University Medical Center, Netherlands
Isolation and Characterization of Multipotent Human NKX2-5 Cardiovascular Progenitors

Xuejun H. Parsons, San Diego Regenerative Medicine Institute, USA
Deriving Cardiac Elements from Pluripotent Human Embryonic Stem Cells for Heart Reconstitution

Alexander R. Pinto, Australian Regenerative Medicine Institute, Australia
Tissue Resident CX3CR1-Positive Macrophages and Dendritic Cells in the Injured and Uninjured Heart

Linda W. van Laake, University Medical Center Utrecht, Netherlands
Reporter-Based Isolation of Induced Pluripotent Stem Cell-Derived Cardiomyocytes Reveals Limited Gene Expression Variance

15:30—16:30
Differentiating Stem/Progenitor Cells

Longs Peak
Miriam Brodt-Ivenshitz, Weizmann Institute of Science, Israel
BMP-Mediated Inhibition of FGF Signaling Lies at the Heart of Differentiation

Maria Grazia Perino, National Institutes of Health, USA
Ascorbic Acid Promotes Cardiomyogenesis in Mouse Embryonic Stem Cells via Modulation of SMADs

Antoine J.P. Bondue, Université Libre de Bruxelles, Belgium
Deciphering the Cellular and Transcriptional Hierarchy Acting during the Earliest Step of Multipotent Cardiovascular Progenitor Specification

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:15
Cardiac Stem Cell Sources and Niches
Meeting has ended...abstracts no longer viewable online.

Longs Peak
* Calum A. MacRae, Brigham & Women's Hospital, USA

Edward E. Morrisey, University of Pennsylvania, USA
Regulation of Cardiac Progenitor Expansion and Differentiation by Wnt Signaling

Claudia Zierold, University of Minnesota, USA
LV-Derived Stem Cells: Is it a Feasible Goal from Humans?

Adriana Gittenberger-de Groot, Leiden University Medical Center, Netherlands
Short Talk: From Cardiogenesis to Cardiac Regeneration. Focus on Epicardium Derived Cells

Elaine L. Shelton, Vanderbilt University, USA
Short Talk: The Omentum: A Source of Vascular Smooth Muscle Cells for Development and Repair


Following Session is for Angiogenesis in Health and Disease (X1)

17:00—19:00
Vascular Development and Collaterals
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* Michael Simons, Yale University, USA

Anne C. Eichmann, Yale University School of Medicine, USA
Development of Collaterals

James E. Faber, University of North Carolina, Chapel Hill, USA
Development and Genetics of Collateral Formation and Remodeling

Eleni Tzima, University of North Carolina, USA
A Novel Polarity Complex that Regulates Redox Signaling in Response to Fluid Stress

Suk-Won Jin, University of North Carolina Chapel Hill, USA
Short Talk: Heterogeneity of Developing Vessels: A Unique Role for BMP in Developing Veins

19:15—20:00
Social Hour with Lite Bites

Quandary Peak
19:30—22:00
Poster Session 2

Quandary Peak

WEDNESDAY, MARCH 3

07:00—08:00
Breakfast

Quandary Peak
08:00—11:00
Cardiovascular Genetics (Joint)
Meeting has ended...abstracts no longer viewable online.

Grays/Longs Peaks
* William C. Sessa, Yale University School of Medicine, USA

* Brian H. Annex, University of Virginia, USA

Elizabeth M. McNally, Northwestern University, USA
Dissecting Modifier Genes for Heart and Muscle Disease

Arya Mani, Yale University, USA
The Genetic Link between Coronary Artery Disease and Metabolic Risk Factors

Calum A. MacRae, Brigham & Women's Hospital, USA
Genetic Basis of Atrial Fibrillation

Jonathan G. Seidman, Harvard Medical School, USA
Genetic Mechanisms of Hypertrophic Cardiomyopathy

Christian Kupatt, Technical University Munich, Germany
Short Talk: Pathophysiological Consequences of Chronic Endothelial Angiopoietin-2 Overexpression

09:20—09:40
Coffee Break

Longs Peak Foyer
11:00
On Own for Lunch and Recreation

11:00—13:00
Poster Setup

Quandary Peak
13:00—22:00
Poster Viewing

Quandary Peak
16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Lessons from Cardiac Hypertrophy and Autophagy
Meeting has ended...abstracts no longer viewable online.

Longs Peak
* Jonathan G. Seidman, Harvard Medical School, USA

Leslie A. Leinwand, University of Colorado, Boulder, USA
Sex Differences in Cardiac Hypertrophy: Are they Relevant for Repair?

Joseph A. Hill, University of Texas Southwestern Medical Center, USA
Autophagy in Cardiac Plasticity and Disease

Francis G. Spinale, Medical University of South Carolina, USA
Regulation and Control of the Matrix in Hypertrophy/Failure: Relevance to Cell and Regenerative Repair

Yulia Anatolevna Chudinovskikh†, Russian Cardiovascular Scientific Center, Russia
Short Talk: New Aspects of the Morphological Features and Pathogenesis of Hypertrophic Cardiomyopathy


Following Session is for Angiogenesis in Health and Disease (X1)

17:00—19:15
Micro RNAs in the Endothelium
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* Anne C. Eichmann, Yale University School of Medicine, USA

William C. Sessa, Yale University School of Medicine, USA
Regulation of Vascular Function by miRNAs

Ralf H. Adams, Max Planck Institute for Molecular Biomedicine, Germany
Molecular Regulation of the Angiogenic Endothelial Phenotype

Jason E. Fish, University Health Network, Canada
Short Talk: A Novel Slit/Robo/microRNA-218 Signaling Axis Regulates VEGF-Mediated Endocardial Migration and Heart Tube Formation

Amparo Acker-Palmer, Goethe University, Germany
EphrinB2 Regulates VEGFR2 Function in Developmental and Tumour Angiogenesis

19:00—20:00
Social Hour with Lite Bites

Quandary Peak
19:30—22:00
Poster Session 3

Quandary Peak

THURSDAY, MARCH 4

07:00—08:00
Breakfast

Quandary Peak
08:00—11:00
Mechanisms in Cardiac Repair
Meeting has ended...abstracts no longer viewable online.

Longs Peak
* Brian H. Annex, University of Virginia, USA

Michael J. Galko, University of Texas M.D. Anderson Cancer Center, USA
The Drosophila Open Circulatory System as a Source of Cells and Signals for Tissue Repair

Nikolaos G. Frangogiannis, Baylor College of Medicine, USA
The Role of the Inflammatory Response in Cardiac Repair

* Howard A. Rockman, Duke University Medical Center, USA
Genetics versus Genes

Roger J. Hajjar, Mount Sinai School of Medicine, USA
Short Talk: Myocardial Delivery of AAV1.SERCA2a in Patients with Advanced Heart Failure: A Phase I/II Clinical Trial


Following Session is for Angiogenesis in Health and Disease (X1)

08:00—11:00
Therapeutic Interventions
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* Frank J. Giordano, Yale University, USA

John Martin, University College London, UK
Gene Therapy or Stem Cell Therapy: Which is the Future for Angiogenesis

Ryan J. Watts, Denali Therapeutics Inc, USA
Antibodies Targeting Vascular and Neuronal Pathways: Understanding Antibodies and the BBB

Donald M. McDonald, University of California, San Francisco, USA
Angiogenesis Inhibitors: Risk and Return

Victor Kotelianski, Promedior, USA
Development of RNAi Therapeutics

Kory Lavine, Washington University School of Medicine, USA
Short Talk: Hedgehog Signaling in Coronary Development, Growth, and Disease

09:20—09:40
Coffee Break

Longs Peak Foyer
11:00
On Own for Lunch and Recreation

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
The Future of Cardiac Repair
Meeting has ended...abstracts no longer viewable online.

Longs Peak
* Roger J. Hajjar, Mount Sinai School of Medicine, USA

Brian H. Annex, University of Virginia, USA
Systems Biology Consideration in Angiogenesis and Cell Therapy: Bench to Bedside

Doris A. Taylor, Texas Heart Institute, USA
Re-Endothelialization of Decellularized Heart Reduces Vascular Thrombogenicity


Following Session is for Angiogenesis in Health and Disease (X1)

17:00—19:00
Phospholipid Signaling and Late-Breaking Science
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* Donald M. McDonald, University of California, San Francisco, USA

Timothy T. Hla, Boston Children's Hospital/Harvard Medical School, USA
S1P Signaling in the Vascular System

Mariona Graupera, IDIBELL, Spain
PI3K Signaling in Angiogenesis

Masahiro Murakami, Yale University School of Medicine, USA
Short Talk:

John Chappell, University of North Carolina, USA
Short Talk: A Novel Form of Vessel Sprout Guidance Requires Soluble Flt-1 (VEGFR-1)

Lydia S. Glaw, University of Virginia, USA
Short Talk: PDGF-B Produced by Bone Marrow-Derived Cells Is Required for Normal Perivascular Coverage after Hypoxia-Induced Angiogenesis

19:00—20:00
Social Hour with Lite Bites

Quandary Peak
20:00—23:00
Entertainment

Quandary Peak

FRIDAY, MARCH 5

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



We gratefully acknowledge additional support for this conference from:

Gilead Sciences, Inc.
American Heart Association's Council on Basic Cardiovascular Sciences


We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13HL099225-01




We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Assistant Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676