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This meeting took place in 2014
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Innate Immunity, Metabolism and Vascular Injury (X8)
Organizer(s) Ajay Chawla, Peter Tontonoz and Gwendalyn J. Randolph
March 23—28, 2014
Whistler Conference Centre • Whistler, British Columbia Canada
Discounted Abstract Deadline: Nov 21, 2013
Abstract Deadline: Dec 19, 2013
Scholarship Deadline: Nov 21, 2013
Discounted Registration Deadline: Jan 23, 2014
Supported by an educational donation provided by Amgen
Joint Meeting:
Complications of Diabetes (X7)
Summary of Meeting:
A chronic low-grade inflammatory response is a defining feature of various metabolic diseases, including atherosclerosis, obesity, and type 2 diabetes. This smoldering inflammation in tissues, whether it is in the vascular bed, white adipose tissue or perivascular fat, is primarily mediated by the innate immune system. Consequently, this Keystone Symposium on Innate Immunity, Metabolism and Vascular Injury will bring together leading investigators in areas of macrophage biology, vascular inflammation, atherosclerosis, and obesity-induced metabolic disease. Sessions will encompass a broad range of topics highlighting the importance of and mechanisms by which innate immunity contributes to progression of metabolic diseases, including monocyte development and trafficking, macrophage activation in vascular bed and adipose tissues, and systems biology of myeloid cells. Exciting new developments in sensing of metabolic stress by inflammasomes, clearance of apoptotic cells by macrophages, and initiation of necrotic cell death programs will also be discussed. These basic studies will be complemented by talks discussing new strategies for promoting plaque regression, and targeting innate inflammation to treat insulin resistance, type 2 diabetes, and coronary artery disease.
View Scholarships/Awards
A chronic low-grade inflammatory response is a defining feature of various metabolic diseases, including atherosclerosis, obesity, and type 2 diabetes. This smoldering inflammation in tissues, whether it is in the vascular bed, white adipose tissue or perivascular fat, is primarily mediated by the innate immune system. Consequently, this Keystone Symposium on Innate Immunity, Metabolism and Vascular Injury will bring together leading investigators in areas of macrophage biology, vascular inflammation, atherosclerosis, and obesity-induced metabolic disease. Sessions will encompass a broad range of topics highlighting the importance of and mechanisms by which innate immunity contributes to progression of metabolic diseases, including monocyte development and trafficking, macrophage activation in vascular bed and adipose tissues, and systems biology of myeloid cells. Exciting new developments in sensing of metabolic stress by inflammasomes, clearance of apoptotic cells by macrophages, and initiation of necrotic cell death programs will also be discussed. These basic studies will be complemented by talks discussing new strategies for promoting plaque regression, and targeting innate inflammation to treat insulin resistance, type 2 diabetes, and coronary artery disease.
View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference
SUNDAY, MARCH 23
MONDAY, MARCH 24
TUESDAY, MARCH 25
WEDNESDAY, MARCH 26
THURSDAY, MARCH 27
FRIDAY, MARCH 28
Conference Program Print | View meeting in 12 hr (am/pm) time
SUNDAY, MARCH 23
08:00—09:00
Opening Remarks
Meeting has ended...abstracts no longer viewable online.
Ajay Chawla,
University of California, San Francisco, USA
Peter Tontonoz,
University of California, Los Angeles, USA
Gwendalyn J. Randolph,
Washington University, USA
08:15—09:15
Keynote Address
Meeting has ended...abstracts no longer viewable online.
*
Susan Quaggin,
Northwestern University, USA
Michael A. Brownlee,
Albert Einstein College of Medicine, USA
The Molecular Basis of Diabetic Complications
The Molecular Basis of Diabetic Complications
08:15—10:45
Monocytes: Development and Disease
Meeting has ended...abstracts no longer viewable online.
*
Gwendalyn J. Randolph,
Washington University, USA
Frederic Geissmann,
Memorial Sloan Kettering Cancer Center, USA
Developmental and Functional Heterogeneity of Macrophages
Developmental and Functional Heterogeneity of Macrophages
Alan R. Tall,
Columbia University, USA
Regulation of Hematopoiesis by Cholesterol
Regulation of Hematopoiesis by Cholesterol
Tiffany Horng,
ShanghaiTech University, China
Short Talk: The TSC-mTOR Pathway Regulates Macrophage Polarization
Short Talk: The TSC-mTOR Pathway Regulates Macrophage Polarization
Partha Dutta,
Massachusetts General Hospital Harvard Medical School, USA
Short Talk: Activation of CCR2+ Hematopoietic Stem Cells after Myocardial Infarction
Short Talk: Activation of CCR2+ Hematopoietic Stem Cells after Myocardial Infarction
09:15—11:30
Metabolic Dysregulation and the Pathogenesis of Diabetic Cardiovascular Disease
Meeting has ended...abstracts no longer viewable online.
Dysreguation of metabolism and impaired heart and vascular function. Defining the pathways contributing to impaired cardiovascular function and opportinuties to correct this will be the focus of this session.
*
Susan Quaggin,
Northwestern University, USA
Philipp E. Scherer,
University of Texas Southwestern Medical Center, USA
Adipocyte Origin of Insulin Resistance, Chronic Inflammation and Lipotoxicity
Adipocyte Origin of Insulin Resistance, Chronic Inflammation and Lipotoxicity
Richard J.M. Coward,
University of Bristol, UK
Insulin Resistance and the Kidney
Insulin Resistance and the Kidney
Christopher B. Newgard,
Duke University Medical Center, USA
Metabolomics and Cardiometabolic Disease Mechanisms
Metabolomics and Cardiometabolic Disease Mechanisms
Kyoungmin Park,
Joslin Diabetes Center, USA
Short Talk: Direct Demonstration that Overexpression of IRS1 and Enhanced Insulin Actions in Vascular Endothelial Cells Can Reduce Atherosclerosis via a Novel Pathway to Activate eNOS
Short Talk: Direct Demonstration that Overexpression of IRS1 and Enhanced Insulin Actions in Vascular Endothelial Cells Can Reduce Atherosclerosis via a Novel Pathway to Activate eNOS
14:30—16:30
Workshop 1
*
Ichiro Manabe,
Chiba University, Japan
Miyako Tanaka,
Nagoya University, Japan
Mincle, a Novel Pathogen Sensor in Macrophages, Underlies Obesity-Induced Adipose Tissue Fibrosis in Mice
Mincle, a Novel Pathogen Sensor in Macrophages, Underlies Obesity-Induced Adipose Tissue Fibrosis in Mice
Joel D. Schilling,
Washington University School of Medicine, USA
Inflammatory-Metabolic Crosstalk in Macrophages: The Role of the Lysosome
Inflammatory-Metabolic Crosstalk in Macrophages: The Role of the Lysosome
Bruno M. Carvalho,
University of Pernambuco, Brazil
Splenic Monocytes and Macrophages Mediate Insulin Resistance in Obesity
Splenic Monocytes and Macrophages Mediate Insulin Resistance in Obesity
Dario A. Gutierrez,
Merck Research Labs Cambridge Exploratory Science Center, USA
Kit Deficiency, But Not Lack of Mast Cells, Has a Profound Effect on Adiposity and Obesity-Induced Insulin Resistance
Kit Deficiency, But Not Lack of Mast Cells, Has a Profound Effect on Adiposity and Obesity-Induced Insulin Resistance
Anca Dana E. Dobrian,
Eastern Virginia Medical School, USA
Signal Transducer and Activator 4 (STAT4) Deficiency in Subsets of Hematopoietic Cells Improves Metabolic Phenotype by Reducing Adipose Tissue and Islet Inflammation in Obesity and Insulin Resistance
Signal Transducer and Activator 4 (STAT4) Deficiency in Subsets of Hematopoietic Cells Improves Metabolic Phenotype by Reducing Adipose Tissue and Islet Inflammation in Obesity and Insulin Resistance
Jonathan R. Brestoff,
Perelman School of Medicine, University of Pennsylvania, USA
Group 2 Innate Lymphoid Cell Responses in White Adipose Tissue Are Conserved in Mice and Humans
Group 2 Innate Lymphoid Cell Responses in White Adipose Tissue Are Conserved in Mice and Humans
17:00—19:00
Genomics of Myeloid Cells
Meeting has ended...abstracts no longer viewable online.
*
Alan R. Tall,
Columbia University, USA
Christopher K. Glass,
University of California, San Diego, USA
A Genome-Wide View of Macrophage Activation
A Genome-Wide View of Macrophage Activation
Laszlo Nagy,
Sanford-Burnham Medical Research Institute at Lake Nona, USA
The Genomic Basis of a Retinoid X Receptor-Induced Angiogenic Macrophage Phenotype
The Genomic Basis of a Retinoid X Receptor-Induced Angiogenic Macrophage Phenotype
Chih-Hao Lee,
Harvard University School of Public Health, USA
Serum Lipidome in Metabolic and Immune Functions
Serum Lipidome in Metabolic and Immune Functions
Ekaterina K. Koltsova,
Fox Chase Cancer Center, USA
Short Talk: Interleukin-27 Signaling Curbs Inflammation in Atherosclerosis
Short Talk: Interleukin-27 Signaling Curbs Inflammation in Atherosclerosis
17:00—19:00
Stem Cells in Diabetic Tissue Repair I
Meeting has ended...abstracts no longer viewable online.
Impaired tissues repair is a hallmark of the diabetic state. Recent studies suggest impaired stem cell mobilization may contribute. This session overview the contribution of stem-cell "opathy" to diabetic complications.
*
Michael A. Brownlee,
Albert Einstein College of Medicine, USA
Rohit N. Kulkarni,
Joslin Diabetes Center, Harvard Medical School, USA
Using iPS Cells to Investigate Complications in Type 1 Diabetes
Using iPS Cells to Investigate Complications in Type 1 Diabetes
Geoffrey C. Gurtner,
Stanford University, USA
Stem Cell Defects and Impaired Diabetic Wound Healing
Stem Cell Defects and Impaired Diabetic Wound Healing
Andras Nagy,
Mount Sinai Hospital, University of Toronto, Canada
Alternative Sources of Stem Cells for Tissue Repair
Alternative Sources of Stem Cells for Tissue Repair
Mattia Albiero,
Venetian Institute of Molecular Medicine, Italy
Short Talk: Diabetes Causes Bone Marrow Autonomic Neuropathy and Impairs Stem Cell Mobilization via Dysregulated p66Shc and Sirt1
Short Talk: Diabetes Causes Bone Marrow Autonomic Neuropathy and Impairs Stem Cell Mobilization via Dysregulated p66Shc and Sirt1
08:00—11:15
Macrophages and Vascular Inflammation (Joint)
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*
Christopher K. Glass,
University of California, San Diego, USA
Kathryn J. Moore,
New York University Medical Center, USA
The NLRP3 Inflammasome in Atherosclerosis and Diabetes: Activation from Within
The NLRP3 Inflammasome in Atherosclerosis and Diabetes: Activation from Within
Ira Tabas,
Columbia University, USA
Defective Inflammation Resolution in Atherosclerosis: Mechanisms and Therapeutic Opportunities
Defective Inflammation Resolution in Atherosclerosis: Mechanisms and Therapeutic Opportunities
Peter Tontonoz,
University of California, Los Angeles, USA
Integration of Metabolism and Inflammation by LXRs
Integration of Metabolism and Inflammation by LXRs
Qian Li,
Joslin Diabetes Center, USA
Short Talk: Acceleration of Atherosclerosis by Specific Deletion of Protein Kinase C Isoform in Macrophages: An Anti-Atherosclerotic Role for its Activation in Diabetes
Short Talk: Acceleration of Atherosclerosis by Specific Deletion of Protein Kinase C Isoform in Macrophages: An Anti-Atherosclerotic Role for its Activation in Diabetes
José J. Fuster,
Boston University School of Medicine, USA
Short Talk: Non-Canonical Wnt Signaling Promotes Inflammatory Abdominal Aortic Aneurysm Formation
Short Talk: Non-Canonical Wnt Signaling Promotes Inflammatory Abdominal Aortic Aneurysm Formation
17:00—19:00
Inflammasomes in Metabolic Disease
Meeting has ended...abstracts no longer viewable online.
*
Kathryn J. Moore,
New York University Medical Center, USA
Jorge Henao-Mejia,
University of Pennsylvania and Children's Hospital of Philadelphia, USA
Talk Title to be Announced
Talk Title to be Announced
Jenny P.Y. Ting,
University of North Carolina at Chapel Hill, USA
Fatty Acid Activation of the Inflammasomes
Fatty Acid Activation of the Inflammasomes
Vishva M. Dixit,
Genentech, Inc., USA
The Inflammasome
The Inflammasome
Jon A. Hagar,
University of North Carolina at Chapel Hill, USA
Short Talk: Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock
Short Talk: Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock
17:00—19:00
Emerging Targets for the Treatment of Diabetic Complications
Meeting has ended...abstracts no longer viewable online.
*
Karl Tryggvason,
Karolinska Institutet, Sweden
Susan Quaggin,
Northwestern University, USA
Targeting the Tie2 Pathway for Diabetic Nephropathy
Targeting the Tie2 Pathway for Diabetic Nephropathy
Martin Friedlander,
The Scripps Research Institute, USA
Endothelial Progenitor Cells and Diabetic Retinopathy
Endothelial Progenitor Cells and Diabetic Retinopathy
Ulf P.E. Eriksson,
Karolinska Institutet, Sweden
Short Talk: Targeting VEGF-B as a Treatment of Insulin Resistance, Type 2 Diabetes and Diabetic Co-Morbidities
Short Talk: Targeting VEGF-B as a Treatment of Insulin Resistance, Type 2 Diabetes and Diabetic Co-Morbidities
08:00—09:00
Keynote Address
Meeting has ended...abstracts no longer viewable online.
*
Ajay Chawla,
University of California, San Francisco, USA
Ruslan Medzhitov,
HHMI/Yale University School of Medicine, USA
Inflammation and Diseases of Homeostasis
Inflammation and Diseases of Homeostasis
09:00—11:30
Innate Inflammation and Insulin Resistance
Meeting has ended...abstracts no longer viewable online.
*
Ira Tabas,
Columbia University, USA
Steven E. Shoelson,
Harvard Medical School, Joslin Diabetes Center, USA
Targeting Inflammation to Treat Metabolic Disease
Targeting Inflammation to Treat Metabolic Disease
Richard M. Locksley,
HHMI/University of California, San Francisco, USA
Innate Helper Type 2 Cells (ILC2) and Metabolic Homeostasis
Innate Helper Type 2 Cells (ILC2) and Metabolic Homeostasis
Ajay Chawla,
University of California, San Francisco, USA
Anticipatory Inflammation: Physiologic Functions and Pathologic Consequences
Anticipatory Inflammation: Physiologic Functions and Pathologic Consequences
Dayoung Oh,
University of Texas Southwestern Medical Center, USA
Short Talk: LTB4 Causes Macrophage-Mediated Inflammation and Directly Induces Insulin Resistance
Short Talk: LTB4 Causes Macrophage-Mediated Inflammation and Directly Induces Insulin Resistance
James C. Lo,
Weill Cornell Medicine, USA
Short Talk: Adipsin Is an Adipokine that Improves beta Cell Function in Diabetes
Short Talk: Adipsin Is an Adipokine that Improves beta Cell Function in Diabetes
08:00—11:00
Clinical Therapies on the Horizon for Diabetic Complications
Meeting has ended...abstracts no longer viewable online.
Several novel therapeutics are in phase 2 clinical trials. These trials should be completed by 2014 or earlier. This session will overview the rationale for and results of these trials.
*
David E. Kelley,
Merck & Co., Inc., USA
Daniel J. Drucker,
Lunenfeld-Tanenbaum Research Institute, Canada
Cardiovascular Effects of GLP1R Agonists
Cardiovascular Effects of GLP1R Agonists
Matthew D. Breyer,
Janssen Pharmaceutical Company, USA
Discovery of Novel Treatments for Diabetic Nephropathy
Discovery of Novel Treatments for Diabetic Nephropathy
James W. Russell,
University of Maryland, USA
Nicotinamide Precursors as a Treatment in the Diabetic Nervous System
Nicotinamide Precursors as a Treatment in the Diabetic Nervous System
Edward P. Feener,
KalVista Pharmaceuticals, USA
Plasma Kallikrein Inhibitors for Diabetic Macular Edema
Plasma Kallikrein Inhibitors for Diabetic Macular Edema
Kevin G. Peters,
Aerpio Pharmaceuticals, USA
Short Talk: Novel Approach to Treatment of Diabetic Macular Edema: Activating Tie2 by Inhibition of Vascular Endothelial Protein Tyrosine Phosphatase (VE-PTP)
Short Talk: Novel Approach to Treatment of Diabetic Macular Edema: Activating Tie2 by Inhibition of Vascular Endothelial Protein Tyrosine Phosphatase (VE-PTP)
17:00—19:00
Apoptosis and Necrosis
Meeting has ended...abstracts no longer viewable online.
*
Peter Tontonoz,
University of California, Los Angeles, USA
Yoshihiro Ogawa,
Kyushu University, Japan
Role of Parenchymal-Stromal Cell Interaction in Metabolic Diseases
Role of Parenchymal-Stromal Cell Interaction in Metabolic Diseases
Shigekazu Nagata,
IFReC, Osaka University, Japan
Exposure of Phosphatidylserine and Phosphatidylserine-Dependent Engulfment of Apoptotic Cells
Exposure of Phosphatidylserine and Phosphatidylserine-Dependent Engulfment of Apoptotic Cells
Andrés Hidalgo,
Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III, Spain
Clearance of Aged Neutrophils
Clearance of Aged Neutrophils
A. Phillip West,
Yale University School of Medicine, USA
Short Talk: Altered Mitochondrial DNA Dynamics Elicit a Cell-Intrinsic Antiviral Signaling Program
Short Talk: Altered Mitochondrial DNA Dynamics Elicit a Cell-Intrinsic Antiviral Signaling Program
17:00—18:25
Mitochondrial Biology
Meeting has ended...abstracts no longer viewable online.
*
James W. Russell,
University of Maryland, USA
Navdeep S. Chandel,
Northwestern University, USA
Physiological Roles of Mitochondrial Reactive Oxygen Species
Physiological Roles of Mitochondrial Reactive Oxygen Species
Melinda T. Coughlan,
Baker IDI Heart & Diabetes Institute, Australia
Impaired Mitophagy Activity in Diabetic Nephropathy
Impaired Mitophagy Activity in Diabetic Nephropathy
Moshe Levi,
Georgetown University, USA
Short Talk: G Protein Coupled Receptor TGR5 Activation Prevents Kidney Disease in Mice with Obesity and Diabetes
Short Talk: G Protein Coupled Receptor TGR5 Activation Prevents Kidney Disease in Mice with Obesity and Diabetes
08:00—11:15
Where Are the Missing Genetics in Diabetic Complications? (Joint)
Meeting has ended...abstracts no longer viewable online.
*
Karl Tryggvason,
Karolinska Institutet, Sweden
Search for Diabetic Nephropathy Susceptibility Genes
Search for Diabetic Nephropathy Susceptibility Genes
Caroline S. Fox,
Merck Research Labs, USA
Using GWAS, Exome ChIP and Exome Sequencing as Tools for Understanding Kidney Disease
Using GWAS, Exome ChIP and Exome Sequencing as Tools for Understanding Kidney Disease
Michael G. Rosenfeld,
University of California, San Diego, USA
Enhancer Codes and Regulated Gene Transcription in Development and Disease
Enhancer Codes and Regulated Gene Transcription in Development and Disease
Fredrik Bäckhed,
University of Gothenburg, Sweden
Altered Gut Metagenome in Diabetes - Cause or Consequence
Altered Gut Metagenome in Diabetes - Cause or Consequence
Claudiu V. Komorowsky,
University Clinic Erlangen, Germany
Short Talk: Systems Genetics Facilitates Driver Identification in Human Diabetic Kidney Disease
Short Talk: Systems Genetics Facilitates Driver Identification in Human Diabetic Kidney Disease
Alexandre Stewart,
University of Ottawa Heart Institute, Canada
Short Talk: IRF2BP2, A Novel Transcriptional Regulator of Innate Immunity and Cholesterol Metabolism
Short Talk: IRF2BP2, A Novel Transcriptional Regulator of Innate Immunity and Cholesterol Metabolism
14:30—16:30
Workshop 2
*
Christoph J. Binder,
Medical University of Vienna, Austria
Xin Rong,
HHMI/University of California, Los Angeles, USA
LXRs Regulate ER Stress and Inflammation through Dynamic Modulation of Membrane Phospholipid Composition
LXRs Regulate ER Stress and Inflammation through Dynamic Modulation of Membrane Phospholipid Composition
Mark A. Gillespie,
Institute for Systems Biology, USA
A Systems Approach to Identifying Promoter-Bound LXR Coregulators in Atherosclerosis
A Systems Approach to Identifying Promoter-Bound LXR Coregulators in Atherosclerosis
Siroon Bekkering,
Radboud UMC, Netherlands
oxLDL Augments Long-Term Pro-Inflammatory Cytokine Production and Foam Cell Formation via Epigenetic Histone Modifications of Monocytes
oxLDL Augments Long-Term Pro-Inflammatory Cytokine Production and Foam Cell Formation via Epigenetic Histone Modifications of Monocytes
Suneil K. Koliwad,
University of California, San Francisco, USA
Saturated Fats Engage an IRE1 alpha-Dependent Pathway to Activate the NLRP3 Inflammasome in Murine Myeloid Cells
Saturated Fats Engage an IRE1 alpha-Dependent Pathway to Activate the NLRP3 Inflammasome in Murine Myeloid Cells
Ryan Snodgrass,
Goethe University Frankfurt, Germany
Hypoxia Augments Palmitate-Induced Proinflammatory Activation of Primary Human Macrophages
Hypoxia Augments Palmitate-Induced Proinflammatory Activation of Primary Human Macrophages
Joseph J. Boyle,
Imperial College London, UK
AMPK-ATF1 Regulated Transcription Integrates Iron and Lipid Metabolism in Mhem Macrophages in Vascular Self-Protection from Hemorrhage and Pharmacological Protection with Metformin
AMPK-ATF1 Regulated Transcription Integrates Iron and Lipid Metabolism in Mhem Macrophages in Vascular Self-Protection from Hemorrhage and Pharmacological Protection with Metformin
Maroof Hasan,
Novartis Institutes for BioMedical Research, Switzerland
The Role of Trex1 in Immunometabolism and Autoimmune Disease
The Role of Trex1 in Immunometabolism and Autoimmune Disease
14:30—16:30
Workshop: External Funding for Diabetes Complications Research
Teresa Jones,
NIDDK, National Institutes of Health, USA
Christian Ketchum,
NIDDK, National Institutes of Health, USA
Diabetic Complications Consortium (DiaComp)
Diabetic Complications Consortium (DiaComp)
Tracy Rankin,
NIDDK, National Institutes of Health, USA
Helen D. Nickerson,
Juvenile Diabetes Research Foundation, USA
JDRF Strategy and Priorities in Diabetic Complications
JDRF Strategy and Priorities in Diabetic Complications
17:00—19:00
Progressing Fat and Regressing Cholesterol
Meeting has ended...abstracts no longer viewable online.
*
Ajay Chawla,
University of California, San Francisco, USA
Karine Clément,
INSERM/Sorbonne Universite, France
Extracellular Matrix Remodeling of Adipose Tissue and Metabolic Homeostasis
Extracellular Matrix Remodeling of Adipose Tissue and Metabolic Homeostasis
Edward A. Fisher,
New York University School of Medicine, USA
HDL and Atherosclerosis Regression: Getting Rid of Cholesterol and Macrophages from the Plaque
HDL and Atherosclerosis Regression: Getting Rid of Cholesterol and Macrophages from the Plaque
Gwendalyn J. Randolph,
Washington University, USA
Blood and Lymphatic Vasculature Inflammation in Crohn's Disease
Blood and Lymphatic Vasculature Inflammation in Crohn's Disease
Rachel J. Roth-Flach,
Pfizer Inc., USA
Short Talk: Endothelial MAP4K4 Is a Novel Regulator of Vascular Inflammation and Atherosclerosis
Short Talk: Endothelial MAP4K4 Is a Novel Regulator of Vascular Inflammation and Atherosclerosis
17:00—19:00
Model Systems for Diabetic Complications
Meeting has ended...abstracts no longer viewable online.
The complexity of the systemic effects of chronic hyperglycemia on the organism cannot be reproduced by cell culture. This session will review novel biological systems that can faciliate the study of diabetic complications.
*
Matthew D. Breyer,
Janssen Pharmaceutical Company, USA
Ross L. Cagan,
Mount Sinai School of Medicine, USA
Modeling Diabetic Complications in Drosophila
Modeling Diabetic Complications in Drosophila
Jens Kroll,
Medical Faculty Mannheim, Heidelberg University and DKFZ-ZMBH Alliance, Germany
Modeling Diabetic Complications in Zebrafish
Modeling Diabetic Complications in Zebrafish
Thomas M. Coffman,
NUS Duke Singapore, Singapore
Humanized Mouse Models of Diabetic Nephropathy
Humanized Mouse Models of Diabetic Nephropathy
Hermann Haller,
Hannover Medical School, Germany
Short Talk: A Novel Rapid Animal Model in Zebrafish to Analyse Molecular Mechanisms of Proteinuria and to Identify and to Evaluate Drugs for CKD and Diabetic Nephropathy
Short Talk: A Novel Rapid Animal Model in Zebrafish to Analyse Molecular Mechanisms of Proteinuria and to Identify and to Evaluate Drugs for CKD and Diabetic Nephropathy
19:00—19:15
Concluding Remarks
Meeting has ended...abstracts no longer viewable online.
Ajay Chawla,
University of California, San Francisco, USA
Peter Tontonoz,
University of California, Los Angeles, USA
Gwendalyn J. Randolph,
Washington University, USA
*Session Chair †Invited, not yet responded.
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