Casa Grande Hotel Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

Why So Many Ways to Die? Apoptosis, Necroptosis, Pyroptosis and Beyond (T3)

Scientific Organizers: Karina R. Bortoluci, Vishva M. Dixit and Andreas E. Strasser


November 19—23, 2019

Casa Grande Hotel, Guarujá, São Paulo, Brazil


Organized in collaboration with the São Paulo Research Foundation (FAPESP)
Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation


Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.
BEWARE of booking lodging through companies unaffiliated with Keystone Symposia. Click here for more details.

Keystone Symposia is committed to maintaining a positive and respectful environment at its meetings. To this end, please review and comply with our policies.

DEADLINES:
*All deadlines end at 11:59 PM US Mountain Standard Time
Global Health Travel Award Deadline: Jul 16, 2019 [details]
Scholarship Deadline: Jul 30, 2019 [details]
Discounted Abstract Deadline: Jul 18, 2019 [details]
Abstract Deadline: Aug 20, 2019 [details]
Discounted Registration Deadline: Sep 19, 2019 [details]


Click here to view Cancellation Policy

Register Yourself Deadlines and Fees

Rates and Deadlines listed below are for the 2020-T3 "Why So Many Ways to Die? Apoptosis, Necroptosis, Pyroptosis and Beyond" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details
Before and On July 18, 2019 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details
After July 18, 2019 until October 8, 2019 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details
July 30, 2019 n/a
Discounted NON-STUDENT Registration
More details
Before and On September 19, 2019 845.00 USD
(includes 200.00 discount)
Regular NON-STUDENT Registration
More details
After September 19, 2019 1045.00 USD
Discounted STUDENT Registration
More details
Before and On September 19, 2019 620.00 USD
(includes 200.00 discount)
Regular STUDENT Registration
More details
After September 19, 2019 820.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will accept no liability for money loss through bank charges, transfers or currency fluctuations.




Discounted Abstract Deadline: July 18, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time

Abstract Submission Fee: 100.00 USD*
Submission by this date receives 50.00 USD discount.
*50.00 USD will be applied to Registration Fee when you register

Abstract Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadlines. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract early allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • accept your abstract online
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
(The Abstract Deadline: is August 20, 2019)

Global Health Travel Award Deadline: July 16, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time


Global Health Travel Award Details: You MUST complete your Global Health Travel Award appplication by the Global Health Travel Award Deadline and complete the other required steps (verify your contact information and submit a recommendation letter) to be considered for a travel award.


Click here to learn more about Global Health Travel Awards.

Scholarship Deadline: July 30, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time


Scholarship Details: You MUST submit your abstract by the Scholarship Deadline and complete the other required steps (submit a scholarship application and submit a mentor letter) to be considered for a scholarship.

Click here to learn more about Scholarships.

Abstract Deadline: August 20, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time


Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register

Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract by the Abstract Deadline allows us to:

  • submit your abstract to organizers to be considered for a short talk
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.

(Discounted Abstract Deadline: is July 18, 2019)

Discounted Registration Deadline: September 19, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time


Registration Fee: 845.00 USD* (includes 200.00 USD discount)
Student Registration Fee: 620.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

After the Discounted Registration Deadline:


Registration Fee: 1045.00 USD*
Student Registration Fee: 820.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

Registration spaces are limited and may fill prior to discounted registration deadline.

Please be advised that some meeting participants have received calls and emails from a number of different housing services, including "Exhibitors Housing Services," “Expo Housing Services,” "Global Housing," etc. THESE COMPANIES ARE NOT AFFILIATED WITH KEYSTONE SYMPOSIA and are not authorized by Keystone Symposia to contact you. These companies may tell you that the meeting is filling, without any actual knowledge to that effect, and pressure you into giving them your credit card number to make a lodging reservation with them.

We highly recommend that you not make a reservation with these companies or any other housing service! These companies' representations to participants have been misleading. Please report any calls or correspondence you might have received to Keystone Symposia and book only through lodging links in your Keystone Symposia account, an established travel agency or directly with the hotel(s) listed on our website.
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Tuesday, November 19 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Saturday, November 23 with a keynote address and closing plenary session from 17:00 to 19:30, followed by a social hour and entertainment. We recommend return travel on Sunday, November 24 in order to fully experience the meeting.

TUESDAY, NOVEMBER 19

16:00—20:00
Arrival and Registration

Imperial Ballroom Foyer
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Imperial Ballroom Terrace

WEDNESDAY, NOVEMBER 20

08:30—09:30
Welcome and Keynote Address
Registered attendees can view abstracts starting on 10/19/2019

Imperial Ballroom
* Karina R. Bortoluci, Federal University of São Paulo, Brazil

Kim Newton, Genentech, Inc., USA
The Cut That Makes the Difference – A Caspase-8 Story

09:30—12:00
Advances in Molecular Control of Cell Death I
Registered attendees can view abstracts starting on 10/19/2019

Imperial Ballroom
* Jonathan C. Kagan, Boston Children's Hospital, USA

Hao Wu, Harvard Medical School, Boston Children's Hospital, USA
Inflammasomes: NLRP3 and Gasdermin D (GSDMD)

Coffee Break

Veit Hornung, Ludwig-Maximilians-University Munich, Germany
Molecular Regulation of Inflammatory Cell Death

Daniel Kastner, National Institutes of Health, USA
Inflammasomes in Auto-Inflammatory Diseases

Niklas A. Schmacke, Ludwig-Maximilians-University Munich, Germany
Short Talk: Priming Enables a NEK7-Independent Route of NLRP3 Activation

Bart Tummers, St. Jude Children's Research Hospital, USA
Short Talk: A Non-Apoptotic Function of Caspase-8 Mediates Inflammation and Blocks the Development of ALPS

12:00—17:00
On Own for Lunch

12:00—13:00
Poster Setup

Imperial Ballroom
13:00—22:00
Poster Viewing

Imperial Ballroom
14:30—16:30
Workshop 1: Host Defense

Imperial Ballroom
* Russell E. Vance, University of California, Berkeley, USA

Youssef Aachoui, University of Arkansas for Med, USA
Innate Lymphocytes Prime Caspase-11 in Neutrophils to Defend against a Cytosol Invasive Bacterium

Thomas Burke, University of California, Berkeley, USA
Inflammasome-Mediated Antagonism of Type I Interferon Enhances Rickettsia Pathogenesis

Laura Migliari Branco, University of São Paulo, Brazil
Molecular Mechanisms Involved in NAIP/NLRC4 Inflammasome Activation

Alejandro Rodriguez Gama, Stowers Institute for Medical Research, USA
The Inflammasome-Nucleating Interactome Reveals Specificity and Crosstalk in Cell Death Signaling

Lucas Secchim Ribeiro, University of Bonn, Germany
Inflammasome Activation and Pyroptosis Drive the Formation of Nuclear Filaments between Macrophages

Kateryna Shkarina, University of Lausanne, Switzerland
Optogenetic Control of Programmed Cell Death Reveals Differential Responses towards Apoptotic and Necrotic Cells

Monica Varela, Leiden University, Netherlands
Mycobacteria Exploit Host Caspase 11 and Gasdermin D Tandem for Phagosome Permeabilization, Macrophage Pyroptosis and Infection Dissemination

16:30—17:00
Coffee Available

Imperial Ballroom Terrace
17:00—19:00
Advances in Molecular Control of Cell Death II
Registered attendees can view abstracts starting on 10/19/2019

Imperial Ballroom
* Domagoj Vucic, Genentech, Inc., USA

Feng Shao, National Institute of Biological Sciences, China
Mechanism and Function of Gasdermin-Mediated Pyroptosis

Eicke Latz, University of Bonn, Germany
Cellular responses to pyroptosis

Oliver Florey, Babraham Institute, UK
Eaten Alive! - Mechanisms and Consequences of Cell Cannibalism

Catherine L. Day, University of Otago, New Zealand
Short Talk: Regulation of Ubiquitin Transfer by TRAF E3 Ligases

Charles L. Evavold, Harvard University, USA
Short Talk: A Genome-Wide CRISPR/Cas9 Screen Identifies Novel Regulators of GSDMD Pore Formation in Engineered Macrophages

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Imperial Ballroom Terrace
19:30—22:00
Poster Session 1

Imperial Ballroom

THURSDAY, NOVEMBER 21

08:30—11:45
Cell Death and Cancer
Registered attendees can view abstracts starting on 10/19/2019

Imperial Ballroom
* Gustavo P. Amarante-Mendes, Universidade de São Paulo, Brazil

Andreas E. Strasser, Walter and Eliza Hall Institute of Medical Research, Australia
Towards Targeting MCL-1 for Cancer Therapy

Henning Walczak, University College London, Cancer Institute, UK
Cell Death and Ubiquitin in Cancer

Coffee Break

Ricardo Weinlich, Hospital Israelita Albert Einstein, Brazil
Necroptosis, Inflammation and Cancer

Ruth M. Kluck, Walter and Eliza Hall Institute of Medical Research, Australia
BAK and BAX in Cancer

Gabriela Brumatti, Walter and Eliza Hall Institute, Australia
Short Talk: RIPping Leukaemias Apart: The Role of RIP Kinase 1 in Acute Myeloid Leukaemia

Dhyan Chandra, Roswell Park Comprehensive Cancer Center, USA
Short Talk: Novel Nuclear-Mitochondrial Crosstalk Regulates Cell Death and Survival in Cancer

Eli Arama, Weizmann Institute of Science, Israel
Short Talk: Parthanatos Steps Out of the Shadows of Cell Death and into the Developmental Spotlight

11:45—17:00
On Own for Lunch

11:45—13:00
Poster Setup

Imperial Ballroom
13:00—22:00
Poster Viewing

Imperial Ballroom
16:30—17:00
Coffee Available

Imperial Ballroom Terrace
17:00—19:00
Consequences of Cell Death
Registered attendees can view abstracts starting on 10/19/2019

Imperial Ballroom
* Jaclyn S. Pearson, Hudson Institute of Medical Research, Australia

Vishva M. Dixit, Genentech, Inc., USA
The Non-Canonical Inflammasome Pathway

Jonathan C. Kagan, Boston Children's Hospital, USA
Regulation of Innate Immunity

John Silke, Walter and Eliza Hall Institute of Medical Research, Australia
Cell Death in Cancer and Inflammation

Konrad Aden, University Hospital Kiel, Germany
Short Talk: XBP-1 Coordinates DNA Damage Induced Stem Cell Repression in the Intestinal Epithelium via p53-Ddit4l-Dependent mTOR Inhibition

Randal Halfmann, Stowers Institute for Medical Research, USA
Short Talk: Waiting to Die: Signalosome Nucleation Kinetically Controls Cell Fate

Caitlin Schneider, McGill University, Canada
Short Talk: Migration-Induced Cell Shattering Due to DOCK8 Deficiency Causes a Type-2 Biased T Helper Response

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Imperial Ballroom Terrace
19:30—22:00
Poster Session 2

Imperial Ballroom

FRIDAY, NOVEMBER 22

08:30—11:30
Cell Death and Host Defense I
Registered attendees can view abstracts starting on 10/19/2019

Imperial Ballroom
* Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital, USA

Petr Broz, University of Lausanne, Switzerland
Cell Death during Bacteria Infections

Ricardo T. Gazzinelli, Fundação Oswaldo Cruz-CPqRR, Brazil
Caspase 8 Mediates Experimental Cerebral Malaria

Coffee Break

Russell E. Vance, University of California, Berkeley, USA
Infammasome-Induced Cell Death and Resistance to Bacterial Pathogens

Karina R. Bortoluci, Federal University of São Paulo, Brazil
Inflammasomes: Cell Death, Cytokines and Beyond

Katie Deets, University of California, Berkeley, USA
Short Talk: Investigating a Role for the NAIP/NLCR4 Inflammasome in Adaptive T Cell Responses

Sergio Costa Oliveira, Universidade Federal de Minas Gerais, Brazil
Short Talk: Guanylate-Binding Protein 5 Licenses Caspase-11 for Gasdermin-D Mediated Host Resistance to Intracellular Bacterial Infection

11:30—17:00
On Own for Lunch

11:30—13:00
Poster Setup

Imperial Ballroom
13:00—22:00
Poster Viewing

Imperial Ballroom
16:30—17:00
Coffee Available

Imperial Ballroom Terrace
17:00—19:00
Cell Death and Host Defense II
Registered attendees can view abstracts starting on 10/19/2019

Imperial Ballroom
* Ricardo T. Gazzinelli, Fundação Oswaldo Cruz-CPqRR, Brazil

Edward A. Miao, University of North Carolina at Chapel Hill, USA
Infectious Models Reveal a Unique Role for Caspase-7 after Cytotoxic Lymphocyte Attack

Dario S. Zamboni, University of São Paulo, Brazil
Inflammasomes in Host Response to Pathogenic Microbes

Larissa D. Cunha, Ribeirao Preto Medical School, University of Sao Paulo, Brazil
Short Talk: Regulation of Macrophage Function by LC3-Associated Phagocytosis

Marcel Doerflinger, Walter and Eliza Hall Institute, Australia
Short Talk: Functional Overlap of Different Cell Death Pathways Ensures Host Protection against Intracellular Bacterial Pathogens

Antonia R. Bass, University of Pennsylvania, USA
Short Talk: Human Noncanonical Inflammasome Responses to Legionella Pneumophila

Kshiti Meera Phulphagar, Max Planck Institute of Biochemistry, Germany
Short Talk: Quantitative Spatial Proteomics Reveals Specific Nlrp3 and Cell Death Mediated Reprogramming of Essential Cellular Functions and Organelles

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Imperial Ballroom Terrace
19:30—22:00
Poster Session 3

Imperial Ballroom

SATURDAY, NOVEMBER 23

08:30—11:45
Manipulating Cell Death for Therapeutic Intervention
Registered attendees can view abstracts starting on 10/19/2019

Imperial Ballroom
* Andreas E. Strasser, Walter and Eliza Hall Institute of Medical Research, Australia

Andrew W. Roberts, Walter and Eliza Hall Institute of Medical Research, Australia
Translational and Clinical Updates on Targeting BCL2 and MCL-1

Jaclyn S. Pearson, Hudson Institute of Medical Research, Australia
The Role of RIPK1 in Controlling Gastrointestinal Bacterial Infections

Coffee Break

Domagoj Vucic, Genentech, Inc., USA
Regulation of Inflammatory Cell Death Signaling by RIP Kinases

Lisa Drew, AstraZeneca, USA
Broad Opportunity of Cell Death Agents as Mono- and Combination Therapies in Haematological and Solid Cancers

Pedro Elias Marques, KU Leuven, Belgium
Short Talk: Displacement of Necrotic Cell Debris In Vivo by a Chemokine-Based Peptide Dampens Tissue Inflammation

Jun Sun, University of Illinois at Chicago, USA
Short Talk: Intestinal Vitamin D Receptor Determines Cell Fate via Apoptosis and Autophagy

Lynn Wong, University of Zurich, Switzerland
Short Talk: TNFR2 Induced Priming of NLRP3-Inflammasome via RIPK1 Leads to Pyroptosis in XIAP Deficient Cells

11:45—17:00
On Own for Lunch

14:30—16:30
Workshop 2: Cancer

Imperial Ballroom
* Laura D. Attardi, Stanford University School of Medicine, USA

Silvina Odete Bustos, Instituto do Câncer do Estado de São Paulo, Brazil
A New Imidazacridine Derivate with Antineoplasic Activity in Melanoma

Annette Jacobsen, Walter and Eliza Hall Institute, Australia
Up Close and Personal with the Necroptotic Death Effector, MLKL: Lessons Learned from Mutagenesis Studies

Bruna dos Santos Mendonça, Brazilian National Cancer Institute, Brazil
Nuclear Localization of X-Linked Inhibitor of Apoptosis Protein (XIAP): Impact on Drug Resistance, Cell Growth and Prognosis in Breast Cancer

Daria Raquel Queiroz de Almeida, University of São paulo, Brazil
Ferroptosis Contributes to MB-PDT Efficacy on Killing Human PDAC Cells

Maria Tanzer, Max Planck Institute of Biochemistry, Germany
Phosphoproteome and Secretome Analysis Reveal Differences between TNF-Induced Apoptosis and Necroptosis

Angelica Beate Winter Boldt, Universidade Federal do Paraná, Brazil
At the Edge of Survival: Genetic Associations for Cell Death in Pemphigus Foliaceus

Mikaela Catherine Coleman, University of Sydney, Australia
Dissecting the Ways to Die: A Single-Cell Assay to Simultaneously Quantify Cell Loss and Discriminate Death Program

16:30—17:00
Coffee Available

Imperial Ballroom Terrace
17:00—17:45
Keynote Address
Registered attendees can view abstracts starting on 10/19/2019

Imperial Ballroom
* Vishva M. Dixit, Genentech, Inc., USA

Shigekazu Nagata, IFReC, Osaka University, Japan
Phosphatidylserine-Dependent Efferocytosis and Entosis

17:45—19:15
Cell Death in Inflammatory Diseases
Registered attendees can view abstracts starting on 10/19/2019

Imperial Ballroom
* John Silke, Walter and Eliza Hall Institute of Medical Research, Australia
Mutations that Prevent Caspase Cleavage of RIPK1 Cause Inflammatory Disease

Francis Ka-Ming Chan, Duke University, USA
RIPK3 in Anti-Viral Immunity and Tissue Homeostasis

Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital, USA
Regulation of Inflammasome Activation and Cell Death

Laura D. Attardi, Stanford University School of Medicine, USA
Deconstructing p53 Cellular Responses and Transcriptional Programs in Tumor Suppression and Developmental Syndromes

19:15—19:30
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 10/19/2019

Imperial Ballroom
19:30—20:30
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Imperial Ballroom Terrace
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Imperial Ballroom

SUNDAY, NOVEMBER 24

 
Departure


*Session Chair †Invited, not yet responded.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Bill & Melinda Gates Foundation São Paulo Research Foundation (FAPESP) - Brazil

We gratefully acknowledge additional support for this conference from:

AdipoGen Life Sciences

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Genentech, Inc.


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Corporate Relations, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Nick Dua, Senior Director, Communications, Email: nickd@keystonesymposia.org,
Phone:+1 970-262-1179