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This meeting took place in 2018
Here are the related meetings in 2019:
Windows on the Brain: Formation and Function of Synapses and Circuits and their Disruption in Disease (A6)
For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.
State of the Brain: Genetic Dissection of Brain Circuits and Behavior in Health and Disease (A2)
Organizer(s) Sean Hill, Hongkui Zeng, Z. Josh Huang and György Buzsáki
January 14—18, 2018
Keystone Resort • Keystone, Colorado USA
Discounted Abstract Deadline: Sep 21, 2017
Abstract Deadline: Oct 19, 2017
Scholarship Deadline: Sep 21, 2017
Discounted Registration Deadline: Nov 20, 2017
Lead Sponsor: Allen Institute for Brain Science
Summary of Meeting:
Identifying and understanding the building blocks of the nervous system and how they interact is a central focus of international efforts to understand the brain. Modern genetic approaches hold the promise of establishing an inventory of cell types, exploring mechanisms of cellular identity, developing tools for experimental manipulations, building a brain-wide cell type atlas, and providing the basis of establishing brain-wide connectivity atlases at cellular resolution. Understanding how diseases and disorders impact cells, synapses and circuitry is essential to guide the development of treatments and therapies. Creating such an atlas of genetically identified cell types and their connectivity will provide key data and knowledge for developing in silico reconstructions of brain circuitry and developing theories of brain structure and function. This conference brings together leading scientists from around the world to present the latest tools, techniques and discoveries in using genetic approaches to understand the cell types of the brain and their role in cognition, behavior and brain diseases and disorders.
View Scholarships/Awards
Identifying and understanding the building blocks of the nervous system and how they interact is a central focus of international efforts to understand the brain. Modern genetic approaches hold the promise of establishing an inventory of cell types, exploring mechanisms of cellular identity, developing tools for experimental manipulations, building a brain-wide cell type atlas, and providing the basis of establishing brain-wide connectivity atlases at cellular resolution. Understanding how diseases and disorders impact cells, synapses and circuitry is essential to guide the development of treatments and therapies. Creating such an atlas of genetically identified cell types and their connectivity will provide key data and knowledge for developing in silico reconstructions of brain circuitry and developing theories of brain structure and function. This conference brings together leading scientists from around the world to present the latest tools, techniques and discoveries in using genetic approaches to understand the cell types of the brain and their role in cognition, behavior and brain diseases and disorders.
View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference
The meeting will begin on Sunday, January 14 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, January 18 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, January 19 in order to fully experience the meeting.
SUNDAY, JANUARY 14
MONDAY, JANUARY 15
TUESDAY, JANUARY 16
WEDNESDAY, JANUARY 17
THURSDAY, JANUARY 18
FRIDAY, JANUARY 19
Conference Program Print | View meeting in 12 hr (am/pm) time
The meeting will begin on Sunday, January 14 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, January 18 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Friday, January 19 in order to fully experience the meeting.
SUNDAY, JANUARY 14
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.
08:00—09:30
Welcome and Keynote Session
Meeting has ended...abstracts no longer viewable online.
*
Sean Hill,
Centre for Addiction and Mental Health, Canada
Catherine G. Dulac,
Harvard University, USA
Molecular and Cellular Architecture of Social Behavior Circuits
Molecular and Cellular Architecture of Social Behavior Circuits
Walter J. Koroshetz,
NINDS, National Institutes of Health, USA
From Genetic Dissection to Neuromodulation: The Promise of the BRAIN Initiative
From Genetic Dissection to Neuromodulation: The Promise of the BRAIN Initiative
Coffee Break
09:50—11:45
Tools and Techniques for Genetic Dissection
Meeting has ended...abstracts no longer viewable online.
*
Edward S. Boyden,
Massachusetts Institute of Technology, USA
Anthony Zador,
Cold Spring Harbor Laboratory, USA
Sequencing the Connectome
Sequencing the Connectome
Qingming Luo,
Huazhong University of Science and Technology, China
Brainsmatics: Deciphering Brain Function with Brain-Wide Genetically Defined Networks
Brainsmatics: Deciphering Brain Function with Brain-Wide Genetically Defined Networks
Viviana Gradinaru,
California Institute of Technology, USA
Gene Delivery Across the Blood-Brain-Barrier, Whole-Body Tissue Clearing, and Optogenetics to Understand and Influence Physiology and Behavior
Gene Delivery Across the Blood-Brain-Barrier, Whole-Body Tissue Clearing, and Optogenetics to Understand and Influence Physiology and Behavior
Alan R. Mardinly,
University of California, Berkeley, USA
Short Talk: Precise Holographic Manipulation of Neural Ensembles in Behaving Animals
Short Talk: Precise Holographic Manipulation of Neural Ensembles in Behaving Animals
17:00—19:00
Towards a Census of Cell Types
Meeting has ended...abstracts no longer viewable online.
*
Walter J. Koroshetz,
NINDS, National Institutes of Health, USA
Hongkui Zeng,
Allen Institute for Brain Science, USA
Building a Cell Type Taxonomy for Mouse Cortical Neurons
Building a Cell Type Taxonomy for Mouse Cortical Neurons
Hideyuki Okano,
Keio University School of Medicine, Japan
Disease Modeling and Brain Mapping using Genetically Modified Marmosets
Disease Modeling and Brain Mapping using Genetically Modified Marmosets
Kee Wui Huang,
Harvard Medical School, USA
Short Talk: Single-Cell Transcriptomic Profiling with Spatial Mapping Reveals Distinct 5-HT Neuron Subtypes in the Dorsal Raphe Nucleus
Short Talk: Single-Cell Transcriptomic Profiling with Spatial Mapping Reveals Distinct 5-HT Neuron Subtypes in the Dorsal Raphe Nucleus
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:00—11:15
Genetic Dissection of Microcircuitry
Meeting has ended...abstracts no longer viewable online.
*
Karel Svoboda,
Janelia Research Campus & Cold Spring Harbor Laboratory, USA
Botond Roska,
IOB, Switzerland
Genetic Dissection of the Retina
Genetic Dissection of the Retina
Liqun Luo,
Stanford University, USA
TRAPing Active Neurons
TRAPing Active Neurons
Coffee Break
Andreas Tolias,
Baylor College of Medicine, USA
The Fabric of the Neocortex
The Fabric of the Neocortex
Z. Josh Huang,
Cold Spring Harbor Laboratory, USA
Cortical Interneuron Types, Subtypes and Connection Specificity
Cortical Interneuron Types, Subtypes and Connection Specificity
Seung-Hee Lee,
Korea Advanced Institutes of Science and Technology, KAIST, South Korea
Short Talk: Locomotion Modulates Audiovisual Integration in the Posterior Parietal Cortex
Short Talk: Locomotion Modulates Audiovisual Integration in the Posterior Parietal Cortex
Balázs József Rózsa,
Hungarian Academy of Sciences, Hungary
Short Talk: Fast 3D Imaging and Re-Activation of Neuronal Networks, Dendrites, and Spines in Several Cubic Millimeter Volumes in Behaving Animals to Understand Visual Representation
Short Talk: Fast 3D Imaging and Re-Activation of Neuronal Networks, Dendrites, and Spines in Several Cubic Millimeter Volumes in Behaving Animals to Understand Visual Representation
14:30—16:30
Workshop 1: Cell Type Discovery using Single-Cell Transcriptomics
*
Sten Linnarsson,
Karolinska Institutet, Sweden
Ariel Levine,
NINDS, National Institutes of Health, USA
Large-Scale Single Nucleus Transcriptional Profiling Defines Spinal Cord Cell Types and Their Activity during Behavior
Large-Scale Single Nucleus Transcriptional Profiling Defines Spinal Cord Cell Types and Their Activity during Behavior
Shristi Pandey,
Harvard University, USA
Spatial Mapping of Cell Types in the Zebrafish Habenula using Single-Cell RNAseq
Spatial Mapping of Cell Types in the Zebrafish Habenula using Single-Cell RNAseq
Damon Polioudakis,
University of California, Los Angeles, USA
A Molecular Taxonomy of Cell Types in Developing Human Cortex
A Molecular Taxonomy of Cell Types in Developing Human Cortex
Marie Aare Bentsen,
University of Washington School of Medicine, USA
A Single-Cell Transcriptomics Roadmap to Investigate Type 2 Diabetes Remission Induced by the Action of Fibroblast Growth Factor 1 in the Brain
A Single-Cell Transcriptomics Roadmap to Investigate Type 2 Diabetes Remission Induced by the Action of Fibroblast Growth Factor 1 in the Brain
Lisa Topolnik,
CRCHUQ, Canada
Transcriptomic Profiling, Connectivity and Network State-Dependent Recruitment of Long-Range VIP-GABAergic Neurons in the Mouse Hippocampus
Transcriptomic Profiling, Connectivity and Network State-Dependent Recruitment of Long-Range VIP-GABAergic Neurons in the Mouse Hippocampus
Zhuzhu Zhang,
The Salk Institute for Biological Studies, USA
Single-Nucleus Methylome and Transcriptome Sequencing Reveals Molecular Differences between Identified Cortical Projection Cell Types
Single-Nucleus Methylome and Transcriptome Sequencing Reveals Molecular Differences between Identified Cortical Projection Cell Types
17:00—19:00
Genetic Dissection of Meso and Macrocircuitry
Meeting has ended...abstracts no longer viewable online.
*
Z. Josh Huang,
Cold Spring Harbor Laboratory, USA
Attila Losonczy,
Columbia University, USA
Dissecting Hippocampal Circuit Dynamics during Temporal Associative Learning
Dissecting Hippocampal Circuit Dynamics during Temporal Associative Learning
Suzana Herculano-Houzel,
Vanderbilt University, USA
It Takes Three Variables to Build a Cortex (and the Human Cortex Is Not Special): Lessons from Comparative Neuroanatomy
It Takes Three Variables to Build a Cortex (and the Human Cortex Is Not Special): Lessons from Comparative Neuroanatomy
Johannes Passecker,
Medical University Vienna, Austria
Short Talk: Activity of Prefrontal Neurons Predict Future Choices during Gambling
Short Talk: Activity of Prefrontal Neurons Predict Future Choices during Gambling
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:00—11:15
Data, Modeling, Informatics
Meeting has ended...abstracts no longer viewable online.
*
Hongkui Zeng,
Allen Institute for Brain Science, USA
Kenneth Harris,
University College London, UK
High-Dimensional Geometry of the Cortical Population Code as Revealed by 10,000-Cell Recordings
High-Dimensional Geometry of the Cortical Population Code as Revealed by 10,000-Cell Recordings
Sean Hill,
Centre for Addiction and Mental Health, Canada
A Digital Reconstruction of Cortical Microcircuitry: From Gene Expression to Emergent Network Activity
A Digital Reconstruction of Cortical Microcircuitry: From Gene Expression to Emergent Network Activity
Coffee Break
Surya Ganguli,
Stanford University, USA
Cell Classification as a Computational Problem
Cell Classification as a Computational Problem
György Buzsáki,
New York University, Langone Medical Center, USA
How Does Circuit Modification Support Learning?
How Does Circuit Modification Support Learning?
Michael Kunst,
Max Planck Institute of Neurobiology, Germany
Short Talk: A Cellular-Resolution Atlas of the Larval Zebrafish Brain
Short Talk: A Cellular-Resolution Atlas of the Larval Zebrafish Brain
Eilif Muller,
EPFL, Switzerland
Short Talk: Recent Advances in Data-Driven Brain Region Reconstruction and Simulation in the Human Brain Project
Short Talk: Recent Advances in Data-Driven Brain Region Reconstruction and Simulation in the Human Brain Project
17:00—19:00
Genetic Dissection of Behavior
Meeting has ended...abstracts no longer viewable online.
*
György Buzsáki,
New York University, Langone Medical Center, USA
Yang Dan,
University of California, Berkeley, USA
Neural Circuits Controlling Sleep
Neural Circuits Controlling Sleep
Karel Svoboda,
Janelia Research Campus & Cold Spring Harbor Laboratory, USA
Cell Type-Specific Analysis of the Cortical Circuits for Motor Planning and Movement Initiation
Cell Type-Specific Analysis of the Cortical Circuits for Motor Planning and Movement Initiation
Marion Ponserre,
Max Planck Institute of Neurobiology, Germany
Short Talk: Organization of Central Amygdala Circuits that Regulate Appetitive Behavior
Short Talk: Organization of Central Amygdala Circuits that Regulate Appetitive Behavior
Scott Waddell,
University of Oxford, UK
Short Talk: Competition between Memories of Opposite Valence Underlies Memory Extinction in Drosophila
Short Talk: Competition between Memories of Opposite Valence Underlies Memory Extinction in Drosophila
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
08:00—11:00
Genetic Dissection of Brain Disorders and Diseases
Meeting has ended...abstracts no longer viewable online.
*
Yang Dan,
University of California, Berkeley, USA
Freda D. Miller,
Hospital for Sick Children, Canada
Extrinsic Regulation of Cellular Genesis during Normal and Pathological Cortex Development
Extrinsic Regulation of Cellular Genesis during Normal and Pathological Cortex Development
Lorna W. Role,
Stony Brook University, USA
Genetic Dissection of Cholinergic Signaling in Memory Disorders
Genetic Dissection of Cholinergic Signaling in Memory Disorders
Coffee Break
Khalil Ramadi,
Massachusetts Institute of Technology, USA
Short Talk: A Chronically Implanted, Remotely-Controlled, Drug Delivery System to Deep Brain Microstructures Elicits Repeatable Behavioral Modulation in a Volume-Dependent Manner
Short Talk: A Chronically Implanted, Remotely-Controlled, Drug Delivery System to Deep Brain Microstructures Elicits Repeatable Behavioral Modulation in a Volume-Dependent Manner
Noam D. Beckmann,
Icahn School of Medicine at Mount Sinai, USA
Short Talk: Multiscale Causal Networks Integrating DNA, RNA, and Proteomic Data Identify VGF as a Novel Key Driver of Alzheimer's Disease
Short Talk: Multiscale Causal Networks Integrating DNA, RNA, and Proteomic Data Identify VGF as a Novel Key Driver of Alzheimer's Disease
Summer Thyme,
Harvard University, USA
Short Talk: Shared Neurobiological Roles of Schizophrenia-Associated Genes
Short Talk: Shared Neurobiological Roles of Schizophrenia-Associated Genes
14:30—16:30
Workshop 2: Genetic Dissection of Circuits and Behavior
*
Lorna W. Role,
Stony Brook University, USA
Yoav Adam,
Harvard University, USA
All-Optical Electrophysiology in Behaving Mice with Enhanced Near Infrared Voltage Sensors
All-Optical Electrophysiology in Behaving Mice with Enhanced Near Infrared Voltage Sensors
Nikolaos Balaskas,
Columbia University, USA
Defining the Genetic Diversity of Spinal Presynaptic Inhibitory Interneurons
Defining the Genetic Diversity of Spinal Presynaptic Inhibitory Interneurons
Takaaki Miyazaki,
National Institute of Genetics, Japan
Anatomical Screening and Live Imaging of Gustatory 2nd-Order Neurons that Link Sugar Detection and Feeding/Reward Systems
Anatomical Screening and Live Imaging of Gustatory 2nd-Order Neurons that Link Sugar Detection and Feeding/Reward Systems
Jean-Francois Poulin,
Northwestern University, USA
Mapping Projections of Dopamine Neuron Subtypes using Intersectional Genetic Strategies
Mapping Projections of Dopamine Neuron Subtypes using Intersectional Genetic Strategies
Kazuki Katori,
University of Tokyo, Japan
Sharp Wave-Associated Activity Pattern of Olfactory Cortical Neurons in the Mouse Piriform Cortex
Sharp Wave-Associated Activity Pattern of Olfactory Cortical Neurons in the Mouse Piriform Cortex
Taehong Yang,
Stanford University, USA
Social Control of Hypothalamus-Mediated Male Aggression
Social Control of Hypothalamus-Mediated Male Aggression
17:00—18:45
From Genetic Dissection to the Clinic
Meeting has ended...abstracts no longer viewable online.
*
Freda D. Miller,
Hospital for Sick Children, Canada
Thomas Portmann,
Circuit Therapeutics, Inc., USA
A Circuit-Based Approach to CNS Drug Discovery: Integrating Optogenetics and Single-Cell Genomics
A Circuit-Based Approach to CNS Drug Discovery: Integrating Optogenetics and Single-Cell Genomics
Edward S. Boyden,
Massachusetts Institute of Technology, USA
Technologies for Analyzing and Controlling Neural Circuits
Technologies for Analyzing and Controlling Neural Circuits
18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Meeting has ended...abstracts no longer viewable online.
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.
*Session Chair †Invited, not yet responded.
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