This meeting took place in 2018



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HIV and Co-Infections: Pathogenesis, Inflammation and Persistence (X8)


Organizer(s) Irini Sereti, Nicolas Chomont and Michaela Müller-Trutwin
April 15—19, 2018
Fairmont Chateau Whistler • Whistler, British Columbia Canada
Discounted Abstract Deadline: Dec 13, 2017
Abstract Deadline: Jan 11, 2018
Scholarship Deadline: Dec 13, 2017
Discounted Registration Deadline: Feb 15, 2018

Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation


Summary of Meeting:
Better understanding of HIV pathogenesis is the cornerstone for advances in HIV prevention and vaccine design, long-term therapies and strategies for remission or eradication. Despite remarkable progress in the care of HIV-infected individuals and successful conversion of HIV into a chronic disease, gaps in knowledge regarding the mechanisms of evasion of immune responses, establishment of latency and persistence, pathways involved in chronic inflammation and the potential role of co-infections persist and hamper the design of targeted interventions. This meeting aims to: 1) Deepen understanding the mechanisms of establishment and maintenance of HIV reservoirs including viral evolution on ART, epigenetic regulations and metabolic states; 2) Provide updates on innovative strategies for HIV remission and control; 3) Determine the role of TB and other co-infections in inflammation and establishment of HIV viral reservoirs; and 4) Explore the pathways that induce chronic inflammation and the molecular interplays between inflammation and viral reservoirs in chronic HIV infection. The conference is novel because it is being paired with Keystone Symposia’s conference on “Tuberculosis: Translating Scientific Findings for Clinical and Public Health Impact.” Of the estimated 34 million people living with HIV in the world today, more than a third are also infected with Mycobacterium tuberculosis. Important questions related to HIV pathogenesis including pathways of inflammation and establishment of reservoirs may be greatly influenced by TB and other co-infections. Inflammation and viral persistence are likely fueled by each other, which provides a rationale for addressing these two topics in the same conference. In addition, the meeting’s joint pairing with one dedicated to TB should facilitate interdisciplinary interactions and highlight the importance of TB in HIV pathogenesis and vice versa.

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Scholarships/Awards

Keystone Symposia Future of Science Fund Scholarship Recipients

Gursev Anmole
Simon Fraser University, Canada

Heeva Baharlou
Westmead Institute for Medical Research, Australia

Collin Richard Diedrich
University of Pittsburgh, USA

Johanne Hovgaard Egedal
Aarhus University, Denmark

Daniela Mónaco
Emory University, USA

Pathogens and Immunity Scholarship Recipients

Rabiah Fardoos
Africa Health Research Institute, South Africa

Keystone Symposia Global Health Travel Award Recipients, funded by the Bill & Melinda Gates Foundation
Funded by Keystone Symposia Global Health Travel Award Recipients, funded by the Bill & Melinda Gates Foundation

Emmanuel Donbraye
Obafemi Awolowo University, Nigeria

Brhanu Teka Endallew
Addis Ababa University, Ethiopia

Sandra Milena Gonzalez Diaz
Universidad de Antioquia, Colombia

Henock Ambachew Haile
College of Medicine & Health Sciences, Hawassa University, Ethiopia

Nneka Uchenna Igboeli
University of Nigeria, Nsukka, Nigeria

Moses Nkechukwu Ikegbunam
Nnamdi Azikiwe University, Nigeria

Onalenna Natasha Moraka
Botswana Harvard AIDS Partnership Institute, Botswana

Susan Mugaba
Medical Research Council, Uganda

Lyle Murray
University of the Witwatersrand, South Africa

Harris Onywera
University of Cape Town, South Africa

Ngozi Mirabel Otuonye
Nigerian Institute of Medical Research, Nigeria

Federico Perdomo Celis
Universidad de Antioquia, Colombia

Abayomi Olusola Sijuade
Ekiti State University, Nigeria

Mai Quynh Trinh
National Institute of Hygiene and Epidemiology, Vietnam

Priyanka Tyagi
Indian Institute of Science, India

Angelica Beate Winter Boldt
Hospital de Clínicas, Brazil